Publications by authors named "Chetan E Chitnis"

100Publications

Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity.

Nat Commun 2020 02 19;11(1):953. Epub 2020 Feb 19.

Malaria Molecular Epidemiology Unit, Malaria Translational Research Unit, Institut Pasteur du Cambodge, Institut Pasteur, Phnom Penh, Cambodia.

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http://dx.doi.org/10.1038/s41467-020-14574-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031336PMC
February 2020

Protein S-Palmitoylation Is Responsive to External Signals and Plays a Regulatory Role in Microneme Secretion in Merozoites.

ACS Infect Dis 2020 03 14;6(3):379-392. Epub 2020 Feb 14.

International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1021/acsinfecdis.9b00321DOI Listing
March 2020

Blood cytokine, chemokine and growth factor profiling in a cohort of pregnant women from tropical countries.

Cytokine 2020 01 9;125:154818. Epub 2019 Sep 9.

ISGlobal, Hospital Clínic - Universitat de Barcelona, Carrer del Rosselló, 132, 08036 Barcelona, Spain; Departmento de Medicina Preventiva y Salud Pública, Universidad de Granada, Facultad de Farmacia, Campus de Cartuja, 18071 Granada, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.154818DOI Listing
January 2020

Role of a patatin-like phospholipase in gametogenesis and malaria transmission.

Proc Natl Acad Sci U S A 2019 08 14;116(35):17498-17508. Epub 2019 Aug 14.

Malaria Parasite Biology and Vaccines Unit, Department of Parasites and Insect Vectors, Institut Pasteur, 75015 Paris, France;

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http://dx.doi.org/10.1073/pnas.1900266116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717283PMC
August 2019

Development of Blood Stage Malaria Vaccines.

Methods Mol Biol 2019 ;2013:199-218

Malaria Parasite Biology and Vaccines Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.

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http://link.springer.com/10.1007/978-1-4939-9550-9_15
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http://dx.doi.org/10.1007/978-1-4939-9550-9_15DOI Listing
March 2020

Recombinant measles vaccine expressing malaria antigens induces long-term memory and protection in mice.

NPJ Vaccines 2019 27;4:12. Epub 2019 Feb 27.

1Viral Genomics and Vaccination, Institut Pasteur, CNRS UMR-3569, 28 rue du Dr Roux, 75015 Paris, France.

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http://dx.doi.org/10.1038/s41541-019-0106-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393439PMC
February 2019

Calcium-dependent phosphorylation of serine repeat antigen 5 triggers merozoite egress.

J Biol Chem 2018 06 1;293(25):9736-9746. Epub 2018 May 1.

From the Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India and

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http://dx.doi.org/10.1074/jbc.RA117.001540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016463PMC
June 2018

Molecular Signaling Involved in Entry and Exit of Malaria Parasites from Host Erythrocytes.

Cold Spring Harb Perspect Med 2017 Oct 3;7(10). Epub 2017 Oct 3.

Department of Parasites and Insect Vectors, Institut Pasteur, 75015 Paris, France.

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http://dx.doi.org/10.1101/cshperspect.a026815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629987PMC
October 2017

Molecular mechanisms that mediate invasion and egress of malaria parasites from red blood cells.

Curr Opin Hematol 2017 May;24(3):208-214

Department of Parasites and Insect Vectors, Malaria Parasite Biology and Vaccines Unit, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1097/MOH.0000000000000334DOI Listing
May 2017

Development of vaccines for Plasmodium vivax malaria.

Vaccine 2015 Dec 1;33(52):7489-95. Epub 2015 Oct 1.

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India; Institut Pasteur, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.09.060DOI Listing
December 2015

The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes.

PLoS Pathog 2014 Dec 18;10(12):e1004520. Epub 2014 Dec 18.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India; Malaria Parasite Biology and Vaccines Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1371/journal.ppat.1004520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270784PMC
December 2014

Reticulocytes from cryopreserved erythroblasts support Plasmodium vivax infection in vitro.

Parasitol Int 2014 Apr 1;63(2):278-84. Epub 2013 Dec 1.

BioService, Malaria Research and Reference Reagent Resource Center (MR4), American Type Culture Collection (ATCC), Manassas, VA 20110-2209, USA.

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http://dx.doi.org/10.1016/j.parint.2013.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943572PMC
April 2014

Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion.

Cell Microbiol 2014 Jan 21;16(1):50-63. Epub 2013 Aug 21.

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

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http://dx.doi.org/10.1111/cmi.12177DOI Listing
January 2014

Key molecular events during host cell invasion by Apicomplexan pathogens.

Curr Opin Microbiol 2013 Aug 27;16(4):432-7. Epub 2013 Jul 27.

National Institute of Immunology, New Delhi, India.

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http://dx.doi.org/10.1016/j.mib.2013.07.004DOI Listing
August 2013

Talking to each other to initiate sexual differentiation.

Cell 2013 May;153(5):945-7

ICREA at Barcelona Centre for International Health Research (CRESIB, Hospital Clinic - Universitat de Barcelona), 08036 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cell.2013.05.013DOI Listing
May 2013

Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities.

Vaccine 2013 Apr;31 Suppl 2:B233-43

PATH Malaria Vaccine Initiative, Washington, DC 20001-2621, USA.

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http://dx.doi.org/10.1016/j.vaccine.2013.02.040DOI Listing
April 2013

Dealing with change: the different microenvironments faced by the malarial parasite.

Mol Microbiol 2013 Apr 11;88(1):1-4. Epub 2013 Mar 11.

International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India.

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http://dx.doi.org/10.1111/mmi.12179DOI Listing
April 2013

A thrombospondin structural repeat containing rhoptry protein from Plasmodium falciparum mediates erythrocyte invasion.

Cell Microbiol 2013 Aug 6;15(8):1341-56. Epub 2013 Mar 6.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

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http://dx.doi.org/10.1111/cmi.12118DOI Listing
August 2013

Ca(2+) -mediated exocytosis of subtilisin-like protease 1: a key step in egress of Plasmodium falciparum merozoites.

Cell Microbiol 2013 Jun 28;15(6):910-21. Epub 2012 Dec 28.

Malaria Group, International Centre for Genetic Engineering and Biotechnology ICGEB, New Delhi, India.

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http://doi.wiley.com/10.1111/cmi.12086
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http://dx.doi.org/10.1111/cmi.12086DOI Listing
June 2013

Flow cytometry-based methods for measurement of cytosolic calcium and surface protein expression in Plasmodium falciparum merozoites.

Methods Mol Biol 2013 ;923:281-90

International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

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http://dx.doi.org/10.1007/978-1-62703-026-7_19DOI Listing
January 2013

Development of quantitative receptor-ligand binding assay for use as a tool to estimate immune responses against Plasmodium vivax Duffy binding protein Region II.

J Immunoassay Immunochem 2012 ;33(4):403-13

Malaria Group, International Centre for Genetic Engineering & Biotechnology, New Delhi, India.

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http://dx.doi.org/10.1080/15321819.2012.659781DOI Listing
February 2013

Molecular basis of severe malaria.

Proc Natl Acad Sci U S A 2012 Jun 7;109(26):10130-1. Epub 2012 Jun 7.

Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.1207174109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387049PMC
June 2012

Signalling mechanisms involved in apical organelle discharge during host cell invasion by apicomplexan parasites.

Microbes Infect 2012 Aug 23;14(10):820-4. Epub 2012 May 23.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.micinf.2012.05.007DOI Listing
August 2012

Reduction of antimalarial antibodies by HIV infection is associated with increased risk of Plasmodium falciparum cord blood infection.

J Infect Dis 2012 Feb 11;205(4):568-77. Epub 2012 Jan 11.

Barcelona Centre for International Health Research (CRESIB, Hospital Clínic-Universitat de Barcelona), Spain.

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http://dx.doi.org/10.1093/infdis/jir815DOI Listing
February 2012

Molecular interactions and signaling mechanisms during erythrocyte invasion by malaria parasites.

Curr Opin Microbiol 2011 Aug 29;14(4):422-8. Epub 2011 Jul 29.

International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

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https://linkinghub.elsevier.com/retrieve/pii/S13695274110010
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http://dx.doi.org/10.1016/j.mib.2011.07.018DOI Listing
August 2011

Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor.

PLoS One 2011 Apr 29;6(4):e19422. Epub 2011 Apr 29.

Barcelona Centre for International Health Research (CRESIB), Hospital Clínic/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019422PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084855PMC
April 2011

Localization of apical sushi protein in Plasmodium falciparum merozoites.

Mol Biochem Parasitol 2010 Nov 9;174(1):66-9. Epub 2010 Jun 9.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.molbiopara.2010.06.003DOI Listing
November 2010

Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites.

PLoS Pathog 2010 Feb 5;6(2):e1000746. Epub 2010 Feb 5.

Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

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http://dx.doi.org/10.1371/journal.ppat.1000746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816683PMC
February 2010

The effect of intermittent preventive treatment during pregnancy on malarial antibodies depends on HIV status and is not associated with poor delivery outcomes.

J Infect Dis 2010 Jan;201(1):123-31

Barcelona Centre for International Health Research, Hospital Clínic/Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1086/648595DOI Listing
January 2010

Functional and immunological characterization of a Duffy binding-like alpha domain from Plasmodium falciparum erythrocyte membrane protein 1 that mediates rosetting.

Infect Immun 2009 Sep 22;77(9):3857-63. Epub 2009 Jun 22.

Barcelona Centre for International Health Research, Hospital Clínic/Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1128/IAI.00049-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738012PMC
September 2009

Structural insights into chondroitin sulphate A binding Duffy-binding-like domains from Plasmodium falciparum: implications for intervention strategies against placental malaria.

Malar J 2009 Apr 17;8:67. Epub 2009 Apr 17.

Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

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http://dx.doi.org/10.1186/1475-2875-8-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676308PMC
April 2009

Targeting the Plasmodium vivax Duffy-binding protein.

Trends Parasitol 2008 Jan 26;24(1):29-34. Epub 2007 Nov 26.

Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.pt.2007.10.004DOI Listing
January 2008

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax.

Mem Inst Oswaldo Cruz 2007 Jun;102(3):335-9

Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Súo Paulo, Brasil.

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http://dx.doi.org/10.1590/s0074-02762007005000040DOI Listing
June 2007

Immunogenicity of Plasmodium vivax combination subunit vaccine formulated with human compatible adjuvants in mice.

Vaccine 2007 Jul 21;25(28):5166-74. Epub 2007 May 21.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), P.O. Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.vaccine.2007.04.080DOI Listing
July 2007

Pfcrt haplotypes and in-vivo chloroquine response in Sundergarh district, Orissa, India.

Trans R Soc Trop Med Hyg 2007 Jul 10;101(7):650-4. Epub 2007 Apr 10.

Department of Biochemistry and Molecular Biology, Ispat General Hospital, Rourkela-769005, Orissa, India.

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http://dx.doi.org/10.1016/j.trstmh.2007.01.008DOI Listing
July 2007

Immunogenicity of a recombinant malaria vaccine based on receptor binding domain of Plasmodium falciparum EBA-175.

Vaccine 2007 Jan 27;25(5):806-13. Epub 2006 Sep 27.

Malaria Group, International Centre for Genetic Engineering and Biotechnology, P.O. Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.vaccine.2006.09.048DOI Listing
January 2007

Improvement in yield and purity of a recombinant malaria vaccine candidate based on the receptor-binding domain of Plasmodium vivax Duffy binding protein by codon optimization.

Biotechnol Lett 2006 Jul 23;28(14):1109-14. Epub 2006 Jun 23.

Malaria Research Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, India.

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http://link.springer.com/10.1007/s10529-006-9061-3
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http://dx.doi.org/10.1007/s10529-006-9061-3DOI Listing
July 2006

Epidemiology of malaria transmission in forest and plain ecotype villages in Sundargarh District, Orissa, India.

Trans R Soc Trop Med Hyg 2006 Oct 11;100(10):917-25. Epub 2006 May 11.

National Institute of Malaria Research (formerly Malaria Research Centre), Field Station, Sector-5, Rourkela 769002, District Sundargarh, Orissa, India.

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https://academic.oup.com/trstmh/article-lookup/doi/10.1016/j
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http://dx.doi.org/10.1016/j.trstmh.2006.01.007DOI Listing
October 2006

Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain.

Nature 2006 Feb 21;439(7077):741-4. Epub 2005 Dec 21.

Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi-110067, India.

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http://dx.doi.org/10.1038/nature04443DOI Listing
February 2006

Expression and characterization of human malaria parasite Plasmodium falciparum origin recognition complex subunit 1.

Biochem Biophys Res Commun 2005 Nov 30;337(3):955-66. Epub 2005 Sep 30.

Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 67, India.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.131DOI Listing
November 2005

Comparison of IgG reactivities to Plasmodium vivax merozoite invasion antigens in a Brazilian Amazon population.

Am J Trop Med Hyg 2005 Aug;73(2):244-55

Emory Vaccine Center & Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.

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August 2005

Targeted deletion of Plasmodium knowlesi Duffy binding protein confirms its role in junction formation during invasion.

Mol Microbiol 2005 Mar;55(6):1925-34

Malaria Research Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04523.xDOI Listing
March 2005

Mapping binding residues in the Plasmodium vivax domain that binds Duffy antigen during red cell invasion.

Mol Microbiol 2005 Mar;55(5):1423-34

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04484.xDOI Listing
March 2005

A high cell density fermentation strategy to produce recombinant malarial antigen in E. coli.

Biotechnol Lett 2004 Dec;26(24):1891-5

Malaria Research Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1007/s10529-004-6040-4DOI Listing
December 2004

Detection of a Plasmodium vivax erythrocyte binding protein by flow cytometry.

Cytometry A 2005 ;63(1):59-66

Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.

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http://dx.doi.org/10.1002/cyto.a.20098DOI Listing
September 2005

Structural analogs of sialic acid interfere with the binding of erythrocyte binding antigen-175 to glycophorin A, an interaction crucial for erythrocyte invasion by Plasmodium falciparum.

Mol Biochem Parasitol 2004 Nov;138(1):123-9

Malaria Research Group, International Centre for Genetic Engineering and Biotechnology, P.O. Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.molbiopara.2004.07.012DOI Listing
November 2004

Receptor-binding residues lie in central regions of Duffy-binding-like domains involved in red cell invasion and cytoadherence by malaria parasites.

Blood 2005 Mar 2;105(6):2557-63. Epub 2004 Sep 2.

Malaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), PO Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-05-17
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http://dx.doi.org/10.1182/blood-2004-05-1722DOI Listing
March 2005

Evaluation of immune responses elicited in mice against a recombinant malaria vaccine based on Plasmodium vivax Duffy binding protein.

Vaccine 2004 Sep;22(27-28):3727-37

Malaria Research Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), P.O. Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.vaccine.2004.03.030DOI Listing
September 2004