Publications by authors named "Chao-Nan Qian"

100Publications

Cost-effectiveness analysis of proton beam therapy for treatment decision making in paranasal sinus and nasal cavity cancers in China.

BMC Cancer 2020 Jun 26;20(1):599. Epub 2020 Jun 26.

State Key Laboratory of Oncology in South China, 651 Dongfeng East Road, Guangzhou, Guangdong, 510060, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-020-07083-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320568PMC
June 2020

S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.

Oncogene 2020 Jul 17;39(30):5307-5322. Epub 2020 Jun 17.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy; Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-020-1363-8DOI Listing
July 2020

Antioxidants suppress radiation-induced apoptosis via inhibiting MAPK pathway in nasopharyngeal carcinoma cells.

Biochem Biophys Res Commun 2020 Jun 21;527(3):770-777. Epub 2020 May 21.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China; Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China; Guangzhou Concord Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2020.04.093DOI Listing
June 2020

ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner.

Cancer Lett 2020 Jul 17;482:74-89. Epub 2020 Apr 17.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, China; Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2020.04.002DOI Listing
July 2020

PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling.

Mol Cancer Res 2020 06 13;18(6):903-912. Epub 2020 Mar 13.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-19-1142DOI Listing
June 2020

Boron neutron capture therapy of cancer: Critical issues and future prospects.

Thorac Cancer 2019 12 3;10(12):2195-2199. Epub 2019 Nov 3.

Department of Radiation Oncology, Guangzhou Concord Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1759-7714.13232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885431PMC
December 2019

New frontiers in proton therapy: applications in cancers.

Cancer Commun (Lond) 2019 10 22;39(1):61. Epub 2019 Oct 22.

Department of Radiation Oncology, Guangzhou Concord Cancer Center, Guangzhou, 510045, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-019-0407-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805548PMC
October 2019

Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.

Cancer Lett 2020 01 8;468:27-40. Epub 2019 Oct 8.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, 651 Dongfeng Road East, Guangzhou, 510060, PR China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, 510060, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2019.10.008DOI Listing
January 2020

Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: long-term results of a phase III multicentre randomised controlled trial.

Eur J Cancer 2019 09 16;119:87-96. Epub 2019 Aug 16.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2019.07.007DOI Listing
September 2019

Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.

Cancer Manag Res 2019 21;11:5557-5572. Epub 2019 Jun 21.

Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CMAR.S203060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594015PMC
June 2019

Association between Pretreatment Serum High-density Lipoprotein Cholesterol and Treatment Outcomes in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma Treated with Chemoradiotherapy: Findings from a Randomised Trial.

J Cancer 2019 9;10(16):3618-3623. Epub 2019 Jun 9.

Department of Nasopharyngeal carcinoma, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/jca.32621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636306PMC
June 2019

Knockdown of Notch1 inhibits nasopharyngeal carcinoma cell growth and metastasis via downregulation of CCL2, CXCL16, and uPA.

Mol Carcinog 2019 10 3;58(10):1886-1896. Epub 2019 Jul 3.

School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.23082DOI Listing
October 2019

GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.

J Exp Clin Cancer Res 2019 Apr 8;38(1):152. Epub 2019 Apr 8.

State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13046-019-1157-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454633PMC
April 2019

A curative-intent endoscopic surgery for postradiation nasopharyngeal necrosis in patients with nasopharyngeal carcinoma.

Cancer Commun (Lond) 2018 12 22;38(1):74. Epub 2018 Dec 22.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P.R. China.

View Article

Download full-text PDF

Source
https://cancercommun.biomedcentral.com/articles/10.1186/s408
Publisher Site
http://dx.doi.org/10.1186/s40880-018-0338-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303844PMC
December 2018

Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication.

Mol Cell 2018 11 1;72(4):650-660.e8. Epub 2018 Nov 1.

Brain Tumor Center, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Cancer Biology Program, MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, The University of TX, Houston, Texas 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10972765183075
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2018.09.007DOI Listing
November 2018

Tumor vasculature: a sally port for inhibiting cancer cell spreading.

Cancer Commun (Lond) 2018 08 3;38(1):52. Epub 2018 Aug 3.

Nuffield Division of Clinical Laboratory Science, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-018-0322-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076415PMC
August 2018

p53, latent membrane protein 1, bcl-2, and prognosis in nasopharyngeal carcinoma: a meta-analysis.

Histol Histopathol 2019 Feb 31;34(2):103-110. Epub 2018 Jul 31.

Department of Experimental Research, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guang Zhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14670/HH-18-032DOI Listing
February 2019

FMNL1 mediates nasopharyngeal carcinoma cell aggressiveness by epigenetically upregulating MTA1.

Oncogene 2018 11 16;37(48):6243-6258. Epub 2018 Jul 16.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-018-0351-8DOI Listing
November 2018

Identification of a sodium pump Na/K ATPase α1-targeted peptide for PET imaging of breast cancer.

J Control Release 2018 07 17;281:178-188. Epub 2018 May 17.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2018.05.019DOI Listing
July 2018

Decreased macrophage inflammatory protein (MIP)-1α and MIP-1β increase the risk of developing nasopharyngeal carcinoma.

Cancer Commun (Lond) 2018 04 3;38(1). Epub 2018 Apr 3.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-018-0279-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993139PMC
April 2018

SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation.

Mol Cell 2018 05;70(3):502-515.e8

Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA; Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2018.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108545PMC
May 2018

OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma.

Theranostics 2018 8;8(8):2202-2216. Epub 2018 Mar 8.

Department of Experimental Research, Sun Yat-sen University Cancer Center, State Key Laboratory Oncology in South China, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/thno.24003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928881PMC
April 2019

Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression.

Cell Cycle 2018 31;17(8):963-973. Epub 2018 May 31.

a Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine , Sun Yat-Sen University Cancer Center , Guangzhou 510060 , China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384101.2018.1442629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103659PMC
November 2019

Beneficial effects of anti-EGFR agents, Cetuximab or Nimotuzumab, in combination with concurrent chemoradiotherapy in advanced nasopharyngeal carcinoma.

Oral Oncol 2018 05 13;80:1-8. Epub 2018 Mar 13.

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, PR China; Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center; Guangzhou 510060, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2018.03.002DOI Listing
May 2018

Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling.

J Exp Clin Cancer Res 2018 Feb 20;37(1):34. Epub 2018 Feb 20.

State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13046-018-0692-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819171PMC
February 2018

Pretreatment quality of life as a predictor of survival for patients with nasopharyngeal carcinoma treated with IMRT.

BMC Cancer 2018 01 31;18(1):114. Epub 2018 Jan 31.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-4003-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793429PMC
January 2018

The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.

Cancer Lett 2018 09 27;431:230-243. Epub 2017 Oct 27.

Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2017.10.016DOI Listing
September 2018

Concurrent chemoradiotherapy with or without cetuximab for stage II to IVb nasopharyngeal carcinoma: a case-control study.

BMC Cancer 2017 Aug 24;17(1):567. Epub 2017 Aug 24.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine,Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-017-3552-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571586PMC
August 2017

At-home cancer screening: a solution for China and other developing countries with a large population and limited number of healthcare practitioners.

Authors:
Chao-Nan Qian

Chin J Cancer 2017 Aug 21;36(1):68. Epub 2017 Aug 21.

Department of Nasopharyngeal Carcinoma, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-017-0235-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563903PMC
August 2017

BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer.

Cell Death Dis 2017 06 15;8(6):e2874. Epub 2017 Jun 15.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cddis.2017.271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520926PMC
June 2017

Cetuximab or nimotuzumab plus intensity-modulated radiotherapy versus cisplatin plus intensity-modulated radiotherapy for stage II-IVb nasopharyngeal carcinoma.

Int J Cancer 2017 09 23;141(6):1265-1276. Epub 2017 Jun 23.

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.30819DOI Listing
September 2017

Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.

Cell Death Dis 2017 06 1;8(6):e2834. Epub 2017 Jun 1.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cddis.2017.195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520881PMC
June 2017

Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.

Mol Cell 2017 Jun 25;66(5):684-697.e9. Epub 2017 May 25.

Brain Tumor Center, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521213PMC
June 2017

The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients.

Cancer Res Treat 2018 Jan 5;50(1):19-29. Epub 2017 Apr 5.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4143/crt.2016.595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784643PMC
January 2018

Establishment and validation of M1 stage subdivisions for de novo metastatic nasopharyngeal carcinoma to better predict prognosis and guide treatment.

Eur J Cancer 2017 05 7;77:117-126. Epub 2017 Apr 7.

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, PR China; Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.02.029DOI Listing
May 2017

Cancer metastasis: issues and challenges.

Chin J Cancer 2017 Apr 3;36(1):38. Epub 2017 Apr 3.

Center for Translational Medicine, Guangxi Medical University, and Key Laboratory of Longevity and Aging-related Diseases, Ministry of Education, Nanning, 530021, Guangxi, P. R. China.

View Article

Download full-text PDF

Source
https://cancercommun.biomedcentral.com/articles/10.1186/s408
Publisher Site
http://dx.doi.org/10.1186/s40880-017-0206-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379757PMC
April 2017

Combining cetuximab with chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma: A propensity score analysis.

Oral Oncol 2017 04 2;67:167-174. Epub 2017 Mar 2.

Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China; State Key Laboratory of Oncology in Southern China, Guangzhou 510060, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13688375173005
Publisher Site
http://dx.doi.org/10.1016/j.oraloncology.2017.02.026DOI Listing
April 2017

Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: A phase III multicentre randomised controlled trial.

Eur J Cancer 2017 04 16;75:14-23. Epub 2017 Feb 16.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China; Department of Clinical Trial Center, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2016.12.039DOI Listing
April 2017

Survival impact of waiting time for radical radiotherapy in nasopharyngeal carcinoma: A large institution-based cohort study from an endemic area.

Eur J Cancer 2017 03 3;73:48-60. Epub 2017 Feb 3.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China; Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2016.12.009DOI Listing
March 2017

Metformin targets multiple signaling pathways in cancer.

Chin J Cancer 2017 Jan 26;36(1):17. Epub 2017 Jan 26.

Key Laboratory of Longevity and Ageing-related Diseases, Ministry of Education, Nanning, 530021, Guangxi, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-017-0184-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270304PMC
January 2017

For robust big data analyses: a collection of 150 important pro-metastatic genes.

Chin J Cancer 2017 Jan 21;36(1):16. Epub 2017 Jan 21.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
https://cancercommun.biomedcentral.com/articles/10.1186/s408
Publisher Site
http://dx.doi.org/10.1186/s40880-016-0178-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251273PMC
January 2017

Defeating cancer: the 150 most important questions in cancer research and clinical oncology.

Chin J Cancer 2016 12 28;35(1):104. Epub 2016 Dec 28.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-016-0165-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192589PMC
December 2016

Establishment of an innovative staging system for extramedullary plasmacytoma.

BMC Cancer 2016 10 8;16(1):777. Epub 2016 Oct 8.

Department of Nasopharyngeal Carcinoma, State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://bmccancer.biomedcentral.com/articles/10.1186/s12885-0
Publisher Site
http://dx.doi.org/10.1186/s12885-016-2824-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055682PMC
October 2016

With or without reirradiation in advanced local recurrent nasopharyngeal carcinoma: a case-control study.

BMC Cancer 2016 10 7;16(1):774. Epub 2016 Oct 7.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-016-2803-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054630PMC
October 2016

SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor.

Cancer Res 2017 01 26;77(2):579-589. Epub 2016 Sep 26.

State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-16-1281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988090PMC
January 2017

IGFBP6 is a novel nasopharyngeal carcinoma prognostic biomarker.

Oncotarget 2016 Oct;7(42):68140-68150

Key Laboratory of Longevity and Aging-related Diseases, Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.11886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356544PMC
October 2016

Advanced-Stage Nasopharyngeal Carcinoma: Restaging System after Neoadjuvant Chemotherapy on the Basis of MR Imaging Determines Survival.

Radiology 2017 Jan 1;282(1):171-181. Epub 2016 Aug 1.

From the State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine (L.T.L., Q.Y.C., L.Q.T., L.Z., S.S.G., C.M.X., X.W.L., L.G., H.Y.M., M.Y.C., C.Z., X.G., K.J.C., C.N.Q., M.S.Z., J.X.B., M.H.H., J.Y.S., Y.S., J.M., H.Q.M.), Department of Nasopharyngeal Carcinoma (L.T.L., Q.Y.C., L.Q.T., L.Z., S.S.G., L.G., H.Y.M., M.Y.C., C.Z., X.G., K.J.C., C.N.Q., H.Q.M.), Imaging Diagnosis and Interventional Center (C.M.X., X.W.L.), Good Clinical Practice Center (M.H.H.), Department of Molecular Diagnostics (J.Y.S.), and Department of Radiation Oncology (Y.S., J.M.), Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, P.R. China (H.Q.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.2016152540DOI Listing
January 2017

The rationale for preventing cancer cachexia: targeting excessive fatty acid oxidation.

Authors:
Chao-Nan Qian

Chin J Cancer 2016 07 21;35(1):67. Epub 2016 Jul 21.

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-016-0129-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957313PMC
July 2016

Assessing Colorectal Cancer Screening Adherence of Medicare Fee-for-Service Beneficiaries Age 76 to 95 Years.

J Oncol Pract 2016 06 17;12(6):e670-80. Epub 2016 May 17.

South Carolina College of Pharmacy, Columbia, SC; University Hospitals Case Medical Center, Cleveland, OH; Duke University Medical Center, Durham, NC; Emory Rollins School of Public Health, Atlanta, GA; Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JOP.2015.009118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946705PMC
June 2016

Nomograms for predicting long-term survival in patients with non-metastatic nasopharyngeal carcinoma in an endemic area.

Oncotarget 2016 May;7(20):29708-19

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.8823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045427PMC
May 2016

A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Nat Cell Biol 2016 05 18;18(5):561-71. Epub 2016 Apr 18.

Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb3338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888794PMC
May 2016

PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival.

Oncotarget 2016 May;7(18):26604-16

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042002PMC
http://dx.doi.org/10.18632/oncotarget.8445DOI Listing
May 2016

Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new RORγ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation.

Eur J Med Chem 2016 Jun 21;116:13-26. Epub 2016 Mar 21.

Institute of Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou Science Park, Guangzhou, Guangdong 510530, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2016.03.052DOI Listing
June 2016

Critical weight loss predicts poor prognosis in nasopharyngeal carcinoma.

BMC Cancer 2016 Feb 29;16:169. Epub 2016 Feb 29.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-016-2214-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772285PMC
February 2016

Twenty years after: the beautiful hypothesis and the ugly facts.

Chin J Cancer 2016 Feb 24;35:22. Epub 2016 Feb 24.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China.

View Article

Download full-text PDF

Source
https://cancercommun.biomedcentral.com/articles/10.1186/s408
Publisher Site
http://dx.doi.org/10.1186/s40880-016-0087-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766607PMC
February 2016

Prognostic Significance of Preoperative Serum Lactate Dehydrogenase in Upper Urinary Tract Urothelial Carcinoma.

Clin Genitourin Cancer 2016 08 22;14(4):341-345.e3. Epub 2016 Jan 22.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clgc.2016.01.003DOI Listing
August 2016

Prognostic Value of Plasma Epstein-Barr Virus DNA for Local and Regionally Advanced Nasopharyngeal Carcinoma Treated With Cisplatin-Based Concurrent Chemoradiotherapy in Intensity-Modulated Radiotherapy Era.

Medicine (Baltimore) 2016 Feb;95(5):e2642

From the Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine (W-HC, L-QT, S-SG, Q-YC, LZ, L-TL, C-NQ, XG, DX, M-SZ, H-QM); and Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center (L-QT, S-SG, Q-YC, LZ, L-TL, C-NQ, XG , H-QM), Guangzhou, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000002642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748899PMC
February 2016

The effects of hemoglobin levels and their interactions with cigarette smoking on survival in nasopharyngeal carcinoma patients.

Cancer Med 2016 05 28;5(5):816-26. Epub 2016 Jan 28.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864811PMC
May 2016

Revisiting tumor angiogenesis: vessel co-option, vessel remodeling, and cancer cell-derived vasculature formation.

Chin J Cancer 2016 Jan 8;35:10. Epub 2016 Jan 8.

State Key Laboratory of Oncology in South China Collaborative, Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, Guangdong, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-015-0070-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706692PMC
January 2016

IL-8 suppresses E-cadherin expression in nasopharyngeal carcinoma cells by enhancing E-cadherin promoter DNA methylation.

Int J Oncol 2016 Jan 2;48(1):207-14. Epub 2015 Nov 2.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2015.3226DOI Listing
January 2016

The Prognostic Value of Plasma Epstein-Barr Viral DNA and Tumor Response to Neoadjuvant Chemotherapy in Advanced-Stage Nasopharyngeal Carcinoma.

Int J Radiat Oncol Biol Phys 2015 Nov 7;93(4):862-9. Epub 2015 Aug 7.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; and Collaborative Innovation Center for Cancer Medicine, Guangzhou, China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2015.08.003DOI Listing
November 2015

Establishment and Validation of Prognostic Nomograms for Endemic Nasopharyngeal Carcinoma.

J Natl Cancer Inst 2016 Jan 14;108(1). Epub 2015 Oct 14.

: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine (LQT, CFL, JL, WHC, QYC, LZ, SSG, LTL, LG, YSW, DHL, PYH, HYM, YQX, RS, MYC, YJH, XL, LW, CZ, KJC, CNQ, XG, YXZ, HQM, MSZ), Department of Nasopharyngeal Carcinoma (LQT, QYC, LZ, SSG, LTL, LG, YSW, DHL, PYH, HYM, YQX, RS, MYC, YJH, XL, LW, CZ, KJC, CNQ, XG, HQM), Department of Information Technology (CFL), Department of Medical Statistics and Epidemiology, the School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China (LXY); ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China (XPL, YH, YXXX, DPH, SHW, YTP).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv291DOI Listing
January 2016

COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells.

Oncoimmunology 2015 Nov 9;4(11):e1044712. Epub 2015 Jul 9.

State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Sun Yat-Sen University Cancer Center (SYSUCC) ; Guangzhou, China ; Department of Biotherapy; Sun Yat-Sen University Cancer Center (SYSUCC) ; Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2015.1044712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590030PMC
November 2015

Wnt3a: functions and implications in cancer.

Chin J Cancer 2015 Sep 14;34(12):554-62. Epub 2015 Sep 14.

Key Laboratory of Longevity and Ageing-related Diseases, Ministry of Education, Nanning, Guangxi, 530021, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-015-0052-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593336PMC
September 2015

Hepatitis B virus infection and risk of nasopharyngeal carcinoma in southern China.

Cancer Epidemiol Biomarkers Prev 2015 Nov 12;24(11):1766-73. Epub 2015 Sep 12.

Department of Cancer Prevention Center, Sun Yat-sen University Cancer Center, Guangzhou, China. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1055-9965.EPI-15-0344DOI Listing
November 2015

Tumor necrosis predicts poor clinical outcomes in patients with node-negative upper urinary tract urothelial carcinoma.

Jpn J Clin Oncol 2015 Nov 9;45(11):1069-75. Epub 2015 Sep 9.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jjco/hyv127DOI Listing
November 2015

TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma.

Oncotarget 2015 Oct;6(30):29240-53

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/5074
Publisher Site
http://dx.doi.org/10.18632/oncotarget.5074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745723PMC
October 2015

Is Hemoglobin Level in Patients with Nasopharyngeal Carcinoma Still a Significant Prognostic Factor in the Era of Intensity-Modulated Radiotherapy Technology?

PLoS One 2015 27;10(8):e0136033. Epub 2015 Aug 27.

Sun Yat-sen University Cancer Center;State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, P. R. China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P. R. China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136033PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552389PMC
May 2016

Quantitative Contrast-Enhanced Ultrasonic Imaging Reflects Microvascularization in Hepatocellular Carcinoma and Prognosis after Resection.

Ultrasound Med Biol 2015 Oct 23;41(10):2621-30. Epub 2015 Jul 23.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ultrasmedbio.2015.06.004DOI Listing
October 2015

Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area.

Eur J Cancer 2015 Sep 17;51(13):1760-70. Epub 2015 Jun 17.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, PR China; Department of Clinical Study, Sun Yat-sen University Cancer Center, Guangzhou, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2015.05.025DOI Listing
September 2015

MEK inhibitor diminishes nasopharyngeal carcinoma (NPC) cell growth and NPC-induced osteoclastogenesis via modulating CCL2 and CXCL16 expressions.

Tumour Biol 2015 Nov 10;36(11):8811-8. Epub 2015 Jun 10.

Key Laboratory of Longevity and Aging-related Diseases, Ministry of Education, Nanning, Guangxi, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13277-015-3595-8DOI Listing
November 2015

New surgical staging system for patients with recurrent nasopharyngeal carcinoma based on the AJCC/UICC rTNM classification system.

Eur J Cancer 2015 Sep 5;51(13):1771-9. Epub 2015 Jun 5.

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, PR China; Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2015.05.014DOI Listing
September 2015

Phase I trial of adoptively transferred tumor-infiltrating lymphocyte immunotherapy following concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma.

Oncoimmunology 2015 Feb 6;4(2):e976507. Epub 2015 Mar 6.

State Key Laboratory of Oncology in South China; Sun Yat-sen University Cancer Center ; Guangzhou, China ; Collaborative Innovation Center of Cancer Medicine; Sun Yat-sen University Cancer Center ; Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/23723556.2014.976507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404907PMC
February 2015

Elevated high-sensitivity C-reactive protein levels predict decreased survival for nasopharyngeal carcinoma patients in the intensity-modulated radiotherapy era.

PLoS One 2015 13;10(4):e0122965. Epub 2015 Apr 13.

State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122965PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395211PMC
January 2016

Different prognostic values of plasma Epstein-Barr virus DNA and maximal standardized uptake value of 18F-FDG PET/CT for nasopharyngeal carcinoma patients with recurrence.

PLoS One 2015 8;10(4):e0122756. Epub 2015 Apr 8.

The State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122756PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390333PMC
March 2016