Bernd Kreikemeyer

Bernd Kreikemeyer

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Bernd Kreikemeyer

Publications by authors named "Bernd Kreikemeyer"

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A Versatile Biocompatible Antibiotic Delivery System Based on Self-Assembling Peptides with Antimicrobial and Regenerative Potential.

Adv Healthc Mater 2019 Apr 15:e1900167. Epub 2019 Apr 15.

Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057, Rostock, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.2019001
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http://dx.doi.org/10.1002/adhm.201900167DOI Listing
April 2019

Resistant Gram-Negative Bacteria and Diagnostic Point-of-Care Options for the Field Setting during Military Operations.

Biomed Res Int 2018 12;2018:9395420. Epub 2018 Jun 12.

Department of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1155/2018/9395420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020508PMC
January 2019

Arginine-Depleting Enzymes - An Increasingly Recognized Treatment Strategy for Therapy-Refractory Malignancies.

Cell Physiol Biochem 2018 22;51(2):854-870. Epub 2018 Nov 22.

Department of Medicine, Clinic III-Hematology/ Oncology/Palliative Care, Rostock University Medical Center, University of Rostock, Rostock,

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http://dx.doi.org/10.1159/000495382DOI Listing
December 2018

Porphyromonas gingivalis Peptidyl Arginine Deiminase Can Modulate Neutrophil Activity via Infection of Human Dental Stem Cells.

J Innate Immun 2018 1;10(4):264-278. Epub 2018 Jun 1.

Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany.

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https://www.karger.com/Article/FullText/489020
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http://dx.doi.org/10.1159/000489020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158109PMC
June 2018

Vitamin D administration leads to a shift of the intestinal bacterial composition in Crohn's disease patients, but not in healthy controls.

J Dig Dis 2018 Apr 27;19(4):225-234. Epub 2018 Apr 27.

Division of Gastroenterology and Endocrinology, Department of Medicine II, Rostock University Medical Center, Rostock, Germany.

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http://dx.doi.org/10.1111/1751-2980.12591DOI Listing
April 2018

Microbiome and Culture Based Analysis of Chronic Rhinosinusitis Compared to Healthy Sinus Mucosa.

Front Microbiol 2018 17;9:643. Epub 2018 Apr 17.

Department of Otorhinolaryngology, Head and Neck Surgery, University Medicine Rostock, Rostock, Germany.

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http://dx.doi.org/10.3389/fmicb.2018.00643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932350PMC
April 2018

Streptavidin-coated surfaces suppress bacterial colonization by inhibiting non-specific protein adsorption.

J Biomed Mater Res A 2018 03 18;106(3):758-768. Epub 2017 Nov 18.

Laboratory of Biophysics, Faculty of Applied Natural Sciences, Westphalian University of Applied Sciences, Recklinghausen, D-45665, Germany.

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http://dx.doi.org/10.1002/jbm.a.36276DOI Listing
March 2018

Mechanical characteristics of beta sheet-forming peptide hydrogels are dependent on peptide sequence, concentration and buffer composition.

R Soc Open Sci 2018 Mar 14;5(3):171562. Epub 2018 Mar 14.

School of Life Sciences, Institute for Chemistry and Bioanalytics, University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland.

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http://dx.doi.org/10.1098/rsos.171562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882690PMC
March 2018

Investigating the association between African spontaneously fermented dairy products, faecal carriage of Streptococcus infantarius subsp. infantarius and colorectal adenocarcinoma in Kenya.

Acta Trop 2018 Feb 25;178:10-18. Epub 2017 Oct 25.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland; University of Basel, Petersplatz 1, 4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.actatropica.2017.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766739PMC
February 2018

Identification and Characterization of Serotype-Specific Variation in Group A Streptococcus Pilus Expression.

Infect Immun 2018 02 22;86(2). Epub 2018 Jan 22.

Department of Microbiology & Immunology, University of Nevada, Reno, School of Medicine, Reno, Nevada, USA

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http://dx.doi.org/10.1128/IAI.00792-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778356PMC
February 2018

A Glycine Riboswitch in Controls Expression of a Sodium:Alanine Symporter Family Protein Gene.

Front Microbiol 2018 20;9:200. Epub 2018 Feb 20.

Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Rostock, Germany.

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http://dx.doi.org/10.3389/fmicb.2018.00200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829553PMC
February 2018

Environmental Factors Support the Formation of Specific Bacterial Assemblages on Microplastics.

Front Microbiol 2017 19;8:2709. Epub 2018 Jan 19.

Biological Oceanography, Leibniz Institute for Baltic Sea Research Warnemuende (IOW), Rostock, Germany.

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http://dx.doi.org/10.3389/fmicb.2017.02709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785724PMC
January 2018

Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae.

Nat Commun 2017 12 12;8(1):2093. Epub 2017 Dec 12.

Division of Bioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Parkallee 1-40, 23845, Borstel, Germany.

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http://dx.doi.org/10.1038/s41467-017-01720-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727136PMC
December 2017

Port d'Entrée for Respiratory Infections - Does the Influenza A Virus Pave the Way for Bacteria?

Front Microbiol 2017 21;8:2602. Epub 2017 Dec 21.

Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.3389/fmicb.2017.02602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742597PMC
December 2017

Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase.

J Innate Immun 2016 18;8(6):589-600. Epub 2016 Aug 18.

University Medicine, Institute of Medical Microbiology, Virology and Hygiene, Rostock University, Rostock, Germany.

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http://dx.doi.org/10.1159/000448039DOI Listing
October 2017

LL-37 Triggers Formation of Streptococcus pyogenes Extracellular Vesicle-Like Structures with Immune Stimulatory Properties.

J Innate Immun 2016 8;8(3):243-57. Epub 2015 Dec 8.

Center for Infectious Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000441896DOI Listing
September 2017

Deletion of the L-Lactate Dehydrogenase Gene in Leads to a Loss of SpeB Activity and a Hypovirulent Phenotype.

Front Microbiol 2017 21;8:1841. Epub 2017 Sep 21.

Institute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical CentreRostock, Germany.

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http://journal.frontiersin.org/article/10.3389/fmicb.2017.01
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http://dx.doi.org/10.3389/fmicb.2017.01841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613712PMC
September 2017

African fermented dairy products - Overview of predominant technologically important microorganisms focusing on African Streptococcus infantarius variants and potential future applications for enhanced food safety and security.

Int J Food Microbiol 2017 Jun 21;250:27-36. Epub 2017 Mar 21.

Swiss Tropical and Public Health Institute, Socinstrasse 57, Basel, Switzerland; University of Basel, Petersplatz 1, 4003 Basel, Switzerland; Centre Suisse de Recherches Scientifiques en Côte d'Ivoire (CSRS), Km 17, Adiopodoumé, Rte Dabou, 01 BP 1303 Abidjan 01, Côte d'Ivoire. Electronic address:

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http://dx.doi.org/10.1016/j.ijfoodmicro.2017.03.012DOI Listing
June 2017

Thin magnesium layer confirmed as an antibacterial and biocompatible implant coating in a co‑culture model.

Mol Med Rep 2017 Apr 17;15(4):1624-1630. Epub 2017 Feb 17.

Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, University Medicine Rostock, D‑18057 Rostock, Germany.

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http://dx.doi.org/10.3892/mmr.2017.6218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365004PMC
April 2017

Fast corroding, thin magnesium coating displays antibacterial effects and low cytotoxicity.

Biofouling 2017 04 28;33(4):294-305. Epub 2017 Mar 28.

a Biomechanics and Implant Technology Research Laboratory, Department of Orthopedics , University Medicine Rostock , Rostock , Germany.

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http://dx.doi.org/10.1080/08927014.2017.1303832DOI Listing
April 2017

A Novel System for Comparative Analyses of Bone Cells and Bacteria under Electrical Stimulation.

Biomed Res Int 2016 4;2016:5178640. Epub 2016 Dec 4.

Research Laboratory for Biomechanics and Implant Technology, Department of Orthopedics, Rostock University Medical Center, 18057 Rostock, Germany.

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http://dx.doi.org/10.1155/2016/5178640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164905PMC
February 2017

Human dental stem cells suppress PMN activity after infection with the periodontopathogens Prevotella intermedia and Tannerella forsythia.

Sci Rep 2016 12 15;6:39096. Epub 2016 Dec 15.

Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Rostock, Rostock, Germany.

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http://dx.doi.org/10.1038/srep39096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156907PMC
December 2016

Mucosa-attached bacterial community in Crohn's disease coheres with the clinical disease activity index.

Environ Microbiol Rep 2016 Oct 26;8(5):614-621. Epub 2016 May 26.

Division of Gastroenterology and Endocrinology, Department of Medicine II, University Medical Center Rostock, Rostock, Germany.

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http://dx.doi.org/10.1111/1758-2229.12411DOI Listing
October 2016

Co-Culture of S. epidermidis and Human Osteoblasts on Implant Surfaces: An Advanced In Vitro Model for Implant-Associated Infections.

PLoS One 2016 16;11(3):e0151534. Epub 2016 Mar 16.

Biomechanics and Implant Technology Research Laboratory, Department of Orthopedics, University Medicine Rostock, Rostock, Mecklenburg-Western Pomerania, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151534PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794246PMC
July 2016

Alterations in the mucosa-associated bacterial composition in Crohn's disease: a pilot study.

Int J Colorectal Dis 2016 May 7;31(5):961-971. Epub 2016 Mar 7.

Division of Gastroenterology and Endocrinology, Department of Medicine II, University Medical Center Rostock, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany.

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http://dx.doi.org/10.1007/s00384-016-2548-zDOI Listing
May 2016

High intravascular tissue factor-but not extracellular microvesicles-in septic patients is associated with a high SAPS II score.

J Intensive Care 2016 23;4:34. Epub 2016 May 23.

Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1186/s40560-016-0160-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876565PMC
May 2016

Differential neutrophil responses to bacterial stimuli: Streptococcal strains are potent inducers of heparin-binding protein and resistin-release.

Sci Rep 2016 Feb 18;6:21288. Epub 2016 Feb 18.

Department of Medicine Huddinge, Centre for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital, S-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1038/srep21288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758080PMC
February 2016

Streptococcus pyogenes biofilms-formation, biology, and clinical relevance.

Front Cell Infect Microbiol 2015 11;5:15. Epub 2015 Feb 11.

Institute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre Rostock, Germany.

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http://dx.doi.org/10.3389/fcimb.2015.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324238PMC
September 2015

Do oral bacteria alter the regenerative potential of stem cells? A concise review.

J Cell Mol Med 2015 Sep 8;19(9):2067-74. Epub 2015 Jun 8.

Department of Operative Dentistry and Periodontology, University of Rostock, Rostock, Germany.

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http://dx.doi.org/10.1111/jcmm.12613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568911PMC
September 2015

Streptococcus pyogenes triggers activation of the human contact system by streptokinase.

Infect Immun 2015 Aug;83(8):3035-42

Institute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany

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http://dx.doi.org/10.1128/IAI.00180-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496597PMC
August 2015

TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.

J Immunol 2015 Aug 22;195(3):1092-9. Epub 2015 Jun 22.

Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, 69120 Heidelberg, Germany;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1403173
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http://dx.doi.org/10.4049/jimmunol.1403173DOI Listing
August 2015

Interactions of anaerobic bacteria with dental stem cells: an in vitro study.

PLoS One 2014 4;9(11):e110616. Epub 2014 Nov 4.

Department of Operative Dentistry and Periodontology, University of Rostock, Rostock, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110616PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219685PMC
July 2015

Genome-wide analyses of small non-coding RNAs in streptococci.

Front Genet 2015 20;6:189. Epub 2015 May 20.

Institute of Medical Microbiology, Virology, Hygiene and Bacteriology, Rostock University Medical Center Rostock, Germany.

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http://dx.doi.org/10.3389/fgene.2015.00189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438229PMC
June 2015

A dual function of copper in designing regenerative implants.

Biomaterials 2015 Mar 10;44:36-44. Epub 2015 Jan 10.

Laboratory of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.12.022DOI Listing
March 2015

Anaerobic co-culture of mesenchymal stem cells and anaerobic pathogens - a new in vitro model system.

PLoS One 2013 4;8(11):e78226. Epub 2013 Nov 4.

Katja Kriebel Department of Operative Dentistry and Periodontology, University Rostock, Rostock, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078226PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817215PMC
August 2014

A novel role for pro-coagulant microvesicles in the early host defense against streptococcus pyogenes.

PLoS Pathog 2013 1;9(8):e1003529. Epub 2013 Aug 1.

University Medicine, Institute of Medical Microbiology, Virology and Hygiene, Rostock University, Rostock, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1003529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731245PMC
March 2014

Inhibition of Growth and Gene Expression by PNA-peptide Conjugates in Streptococcus pyogenes.

Mol Ther Nucleic Acids 2013 Nov 5;2:e132. Epub 2013 Nov 5.

Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany.

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http://dx.doi.org/10.1038/mtna.2013.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889189PMC
November 2013

Kinetic characterization of arginine deiminase and carbamate kinase from Streptococcus pyogenes M49.

Protein Expr Purif 2013 Sep 16;91(1):61-8. Epub 2013 Jul 16.

Rostock University Medical Centre, Institute of Medical Microbiology, Virology, and Hygiene, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.pep.2013.07.002DOI Listing
September 2013

Heterologous expression of Ralp3 in Streptococcus pyogenes M2 and M6 strains affects the virulence characteristics.

PLoS One 2013 12;8(2):e55109. Epub 2013 Feb 12.

Institute of Medical Microbiology, Virology, and Hygiene, Rostock University Hospital, University of Rostock, Rostock, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055109PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570465PMC
August 2013

Rapid degradation of Streptococcus pyogenes biofilms by PlyC, a bacteriophage-encoded endolysin.

J Antimicrob Chemother 2013 Aug 4;68(8):1818-24. Epub 2013 Apr 4.

Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.

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http://dx.doi.org/10.1093/jac/dkt104DOI Listing
August 2013

Common regulators of virulence in streptococci.

Curr Top Microbiol Immunol 2013 ;368:111-53

Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1007/82_2012_295DOI Listing
July 2013

Regulation of the activity of lactate dehydrogenases from four lactic acid bacteria.

J Biol Chem 2013 Jul 17;288(29):21295-306. Epub 2013 May 17.

Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, 69118 Heidelberg, Germany.

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http://dx.doi.org/10.1074/jbc.M113.458265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774398PMC
July 2013

Protective mechanisms of respiratory tract Streptococci against Streptococcus pyogenes biofilm formation and epithelial cell infection.

Appl Environ Microbiol 2013 Feb 14;79(4):1265-76. Epub 2012 Dec 14.

University of Rostock, Institute of Medical Microbiology, Virology, and Hygiene, Rostock, Germany.

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http://dx.doi.org/10.1128/AEM.03350-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568619PMC
February 2013

The extracellular protein factor Epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an N-terminal domain containing a carbohydrate-binding module.

J Biol Chem 2012 Nov 12;287(45):38178-89. Epub 2012 Sep 12.

Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1074/jbc.M112.376434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488087PMC
November 2012

Heterologous expression of sahH reveals that biofilm formation is autoinducer-2-independent in Streptococcus sanguinis but is associated with an intact activated methionine cycle.

J Biol Chem 2012 Oct 31;287(43):36111-22. Epub 2012 Aug 31.

Institute of Medical Microbiology, Virology and Hygiene, Rostock University Hospital, 18057 Rostock, Germany.

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http://dx.doi.org/10.1074/jbc.M112.379230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476279PMC
October 2012

A five-species transcriptome array for oral mixed-biofilm studies.

PLoS One 2011 14;6(12):e27827. Epub 2011 Dec 14.

Institute of Medical Microbiology, Virology and Hygiene, University Hospital Rostock, Rostock, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027827PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237422PMC
August 2012

Purification, crystallization and preliminary crystallographic analysis of the adhesion domain of Epf from Streptococcus pyogenes.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Jul 28;68(Pt 7):793-7. Epub 2012 Jun 28.

School of Biological Sciences and Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1107/S1744309112020313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388924PMC
July 2012

Role of phosphate in the central metabolism of two lactic acid bacteria--a comparative systems biology approach.

FEBS J 2012 Apr 12;279(7):1274-90. Epub 2012 Mar 12.

Department of Modeling of Biological Processes, COS Heidelberg/BIOQUANT, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08523.xDOI Listing
April 2012

Combining bacterial-immunotherapy with therapeutic antibodies: a novel therapeutic concept.

Vaccine 2012 Apr 13;30(17):2786-94. Epub 2012 Feb 13.

Department of General, Vascular, Thoracic and Transplantation Surgery, Section of Molecular Oncology and Immunotherapy, University of Rostock, Rostock, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2012.01.071DOI Listing
April 2012

Involvement of T6 pili in biofilm formation by serotype M6 Streptococcus pyogenes.

J Bacteriol 2012 Feb 9;194(4):804-12. Epub 2011 Dec 9.

Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.

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http://jb.asm.org/cgi/doi/10.1128/JB.06283-11
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http://dx.doi.org/10.1128/JB.06283-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272948PMC
February 2012

Assembly mechanism of FCT region type 1 pili in serotype M6 Streptococcus pyogenes.

J Biol Chem 2011 Oct 31;286(43):37566-77. Epub 2011 Aug 31.

Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita-Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1074/jbc.M111.239780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199502PMC
October 2011

Avitalized bacteria mediate tumor growth control via activation of innate immunity.

Cell Immunol 2011 17;269(2):120-7. Epub 2011 Mar 17.

Department of General, Vascular, Thoracic and Transplantation Surgery, Section of Molecular Oncology and Immunotherapy, University of Rostock, 18055 Rostock, Germany.

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http://dx.doi.org/10.1016/j.cellimm.2011.03.014DOI Listing
August 2011

Streptococcus pyogenes M49 plasminogen/plasmin binding facilitates keratinocyte invasion via integrin-integrin-linked kinase (ILK) pathways and protects from macrophage killing.

J Biol Chem 2011 Jun 26;286(24):21612-22. Epub 2011 Apr 26.

Institute of Medical Microbiology, Virology and Hygiene, Rostock University Hospital, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1074/jbc.M110.202671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122219PMC
June 2011

Genomic organization, structure, regulation and pathogenic role of pilus constituents in major pathogenic Streptococci and Enterococci.

Int J Med Microbiol 2011 Mar 26;301(3):240-51. Epub 2010 Nov 26.

Institute of Medical Microbiology, Virology and Hygiene, University of Rostock, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2010.09.003DOI Listing
March 2011

Mutation of mitochondrial ATP8 gene improves hepatic energy status in a murine model of acute endotoxemic liver failure.

Life Sci 2011 Feb 15;88(7-8):343-9. Epub 2010 Dec 15.

Institute for Experimental Surgery, University of Rostock, Schillingallee 69 a, 18055 Rostock, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S002432051000539
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http://dx.doi.org/10.1016/j.lfs.2010.12.011DOI Listing
February 2011

Insights into Streptococcus pyogenes pathogenesis from transcriptome studies.

Future Microbiol 2010 Nov;5(11):1675-94

Institute of Medical Microbiology, Virology & Hospital Hygiene, University Hospital Rostock, Schillingallee 70, Rostock, Germany.

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http://dx.doi.org/10.2217/fmb.10.128DOI Listing
November 2010

Non-coding RNA detection methods combined to improve usability, reproducibility and precision.

BMC Bioinformatics 2010 Sep 29;11:491. Epub 2010 Sep 29.

Systems Biology and Bioinformatics Group, University of Rostock, Rostock, Germany.

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http://dx.doi.org/10.1186/1471-2105-11-491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955705PMC
September 2010

Typing of the pilus-protein-encoding FCT region and biofilm formation as novel parameters in epidemiological investigations of Streptococcus pyogenes isolates from various infection sites.

J Med Microbiol 2010 Apr 10;59(Pt 4):442-52. Epub 2009 Dec 10.

Institute of Medical Microbiology, Virology and Hygiene, University Hospital, Schillingallee 70, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1099/jmm.0.013581-0DOI Listing
April 2010

Impact of the Streptococcus pyogenes Mga regulator on human matrix protein binding and interaction with eukaryotic cells.

Int J Med Microbiol 2010 Apr 22;300(4):248-58. Epub 2010 Jan 22.

Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2009.07.004DOI Listing
April 2010

Myosin cross-reactive antigen of Streptococcus pyogenes M49 encodes a fatty acid double bond hydratase that plays a role in oleic acid detoxification and bacterial virulence.

J Biol Chem 2010 Apr 9;285(14):10353-61. Epub 2010 Feb 9.

Department for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, Georg-August-University, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1074/jbc.M109.081851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856241PMC
April 2010

Serotype- and strain- dependent contribution of the sensor kinase CovS of the CovRS two-component system to Streptococcus pyogenes pathogenesis.

BMC Microbiol 2010 Feb 1;10:34. Epub 2010 Feb 1.

University of Rostock, Medical Faculty, Institute of Medical Microbiology, Virology and Hygiene, Department of Med, Microbiology and Hospital Hygiene, Schillingallee 70, 18055 Rostock, Germany.

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http://dx.doi.org/10.1186/1471-2180-10-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823723PMC
February 2010

Plastid production of protein antibiotics against pneumonia via a new strategy for high-level expression of antimicrobial proteins.

Proc Natl Acad Sci U S A 2009 Apr 30;106(16):6579-84. Epub 2009 Mar 30.

Max-Planck-Institut für Molekulare Pflanzenphysiologie, Am Mühlenberg 1, D-14476 Potsdam-Golm, Germany.

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http://dx.doi.org/10.1073/pnas.0813146106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662961PMC
April 2009

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic.

Plant J 2009 Feb 30;57(3):436-45. Epub 2008 Oct 30.

Max-Planck-Institut für Molekulare Pflanzenphysiologie, Am Mühlenberg 1, D-14476 Potsdam-Golm, Germany.

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http://dx.doi.org/10.1111/j.1365-313X.2008.03702.xDOI Listing
February 2009

Lysates of S. pyogenes serotype M49 induce pancreatic tumor growth delay by specific and unspecific antitumor immune responses.

J Immunother 2008 Oct;31(8):704-13

Section of Molecular Oncology and Immunotherapy, Department of General Surgery, University of Rostock, Schillingallee, Rostock, Germany.

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http://dx.doi.org/10.1097/CJI.0b013e3181829f62DOI Listing
October 2008

PlyC, a novel bacteriophage lysin for compartment-dependent proteomics of group A streptococci.

Proteomics 2008 Jan;8(1):140-8

Department of Medical Microbiology and Hospital Hygiene, Hospital of Rostock University, Schillingallee 70, Rostock, Germany.

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http://dx.doi.org/10.1002/pmic.200700001DOI Listing
January 2008

Streptococcus pyogenes serotype-dependent and independent changes in infected HEp-2 epithelial cells.

ISME J 2007 Dec 18;1(8):678-92. Epub 2007 Oct 18.

Department of Medical Microbiology and Hospital Hygiene, Institute of Medical Microbiology, Virology and Hygiene, University Hospital Rostock, Schillingallee 70, Rostock, Germany.

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http://dx.doi.org/10.1038/ismej.2007.54DOI Listing
December 2007

Transcriptome analyses extend understanding of Streptococcus pyogenes regulatory mechanisms and behavior toward immunomodulatory substances.

Int J Med Microbiol 2007 Nov 21;297(7-8):513-23. Epub 2007 Jun 21.

Department of Medical Microbiology, Virology, and Hygiene, University Hospital Rostock, Schillingallee 70, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2007.04.005DOI Listing
November 2007

Characterization of biofilm formation by clinically relevant serotypes of group A streptococci.

Appl Environ Microbiol 2006 Apr;72(4):2864-75

Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1128/AEM.72.4.2864-2875.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449035PMC
April 2006

Streptococcus pyogenes collagen type I-binding Cpa surface protein. Expression profile, binding characteristics, biological functions, and potential clinical impact.

J Biol Chem 2005 Sep 21;280(39):33228-39. Epub 2005 Jul 21.

Department of Medical Microbiology and Hospital Hygiene, Hospital of Rostock University, Schillingallee 70, D-18057 Rostock, Germany.

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http://www.jbc.org/content/early/2005/07/21/jbc.M502896200.f
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http://dx.doi.org/10.1074/jbc.M502896200DOI Listing
September 2005

MsmR, a specific positive regulator of the Streptococcus pyogenes FCT pathogenicity region and cytolysin-mediated translocation system genes.

Mol Microbiol 2005 Aug;57(3):786-803

Department of Medical Microbiology and Hospital Hygiene, Hospital of the Rostock University, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04730.xDOI Listing
August 2005

Analysis of the growth phase-associated transcriptome of Streptococcus pyogenes.

Int J Med Microbiol 2005 Jun;295(3):161-77

Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2005.02.010DOI Listing
June 2005

The intracellular status of Streptococcus pyogenes: role of extracellular matrix-binding proteins and their regulation.

Int J Med Microbiol 2004 Sep;294(2-3):177-88

Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, D-18055 Rostock, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2004.06.017DOI Listing
September 2004

Function of the fibronectin-binding serum opacity factor of Streptococcus pyogenes in adherence to epithelial cells.

Infect Immun 2004 Jul;72(7):4302-8

Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, 18055 Rostock, Germany.

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http://dx.doi.org/10.1128/IAI.72.7.4302-4308.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC427420PMC
July 2004

Streptococcus pyogenes fibronectin-binding protein F2: expression profile, binding characteristics, and impact on eukaryotic cell interactions.

J Biol Chem 2004 Apr 28;279(16):15850-9. Epub 2004 Jan 28.

Department of Medical Microbiology and Hospital Hygiene, Hospital of the Rostock University, Schillingallee 70, 18057 Rostock, Germany.

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http://dx.doi.org/10.1074/jbc.M313613200DOI Listing
April 2004