Benjamin Raby

Benjamin Raby

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Benjamin Raby

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Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search.

Hum Hered 2018 22;83(3):130-152. Epub 2019 Jan 22.

Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1159/000489765DOI Listing
June 2019

The Genetics of Pneumothorax.

Am J Respir Crit Care Med 2019 Jun;199(11):1344-1357

5 Pulmonary Genetics Center, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and.

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https://www.atsjournals.org/doi/10.1164/rccm.201807-1212CI
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http://dx.doi.org/10.1164/rccm.201807-1212CIDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543724PMC
June 2019

Asthma severity, nature or nurture: genetic determinants.

Authors:
Benjamin A Raby

Curr Opin Pediatr 2019 Jun;31(3):340-348

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http://dx.doi.org/10.1097/MOP.0000000000000758DOI Listing
June 2019

DNA methylation is associated with inhaled corticosteroid response in persistent childhood asthmatics.

Clin Exp Allergy 2019 Jun 12. Epub 2019 Jun 12.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/cea.13447DOI Listing
June 2019

A bronchial-airway gene-expression classifier to improve the diagnosis of lung cancer: Clinical outcomes and cost-effectiveness analysis.

Int J Cancer 2019 Apr 11. Epub 2019 Apr 11.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/ijc.32333DOI Listing
April 2019

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-Exacerbated Respiratory Disease: A Prospective Trial.

Am J Respir Crit Care Med 2019 Apr 12. Epub 2019 Apr 12.

Brigham and Women's Hospital Department of Medicine, 370908, Division of Rheumatology, Immunology, and Allergy, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.201809-1755OCDOI Listing
April 2019

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

J Allergy Clin Immunol 2019 Mar 7;143(3):957-969. Epub 2018 Sep 7.

Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, Calif; Department of Medicine, University of California, San Francisco, San Francisco, Calif.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2016.08.057DOI Listing
March 2019

Asthma severity, nature or nurture: genetic determinants.

Authors:
Benjamin A Raby

Curr Opin Pediatr 2019 Mar 20. Epub 2019 Mar 20.

Division of Pulmonary Medicine, Department of Pediatrics, Boston Children's Hospital.

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http://dx.doi.org/10.1097/MOP.0000000000000758DOI Listing
March 2019

TFutils: Data structures for transcription factor bioinformatics.

F1000Res 2019 5;8:152. Epub 2019 Feb 5.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.12688/f1000research.17976.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600865.2PMC
February 2019

A trial of type 12 purinergic (P2Y) receptor inhibition with prasugrel identifies a potentially distinct endotype of patients with aspirin-exacerbated respiratory disease.

J Allergy Clin Immunol 2019 Jan 8;143(1):316-324.e7. Epub 2018 Jun 8.

Department of Medicine, Harvard Medical School, the Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, and the Jeff and Penny Vinik Center, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286686PMC
January 2019

Alpha-1 Antitrypsin Deficiency as an Incidental Finding in Clinical Genetic Testing.

Am J Respir Crit Care Med 2019 Jan;199(2):246-248

1 Brigham and Women's Hospital Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201809-1679LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353005PMC
January 2019

Novel eosinophilic gene expression networks associated with IgE in two distinct asthma populations.

Clin Exp Allergy 2018 Dec 21;48(12):1654-1664. Epub 2018 Nov 21.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/cea.13249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659730PMC
December 2018

Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.

Respir Res 2018 Oct 29;19(1):209. Epub 2018 Oct 29.

Channing Division of Network Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA, 02115, USA.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-018-0890-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206739PMC
October 2018

TREM-1 Response Signatures Common to Expression Profiles of Both Asthma Affection and Asthma Control.

Am J Respir Crit Care Med 2018 Aug;198(3):401-404

1 Brigham and Women's Hospital and Harvard Medical School Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201709-1964LEDOI Listing
August 2018

Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

J Allergy Clin Immunol 2018 06 31;141(6):2282-2286.e6. Epub 2018 Jan 31.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Pulmonary Genetics Center and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.11.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994185PMC
June 2018

A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data.

Sci Rep 2018 Jun 11;8(1):8826. Epub 2018 Jun 11.

Icahn Institute for Genomics and Multiscale Biology and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41598-018-27189-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995932PMC
June 2018

Familial pneumothorax: towards precision medicine.

Thorax 2018 03 28;73(3):270-276. Epub 2017 Dec 28.

Wellcome Trust/MRC Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, UK.

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http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2017-2111
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http://dx.doi.org/10.1136/thoraxjnl-2017-211169DOI Listing
March 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Detecting disease-associated genomic outcomes using constrained mixture of Bayesian hierarchical models for paired data.

PLoS One 2017 30;12(3):e0174602. Epub 2017 Mar 30.

Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174602PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373614PMC
August 2017

A new diagnosis of Williams-Beuren syndrome in a 49-year-old man with severe bullous emphysema.

Am J Med Genet A 2017 Aug 2;173(8):2235-2239. Epub 2017 Jun 2.

Pulmonary Genetics Center, Division of Pulmonary and Critical Care Medicine, and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajmg.a.38289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509496PMC
August 2017

Whole genome prediction and heritability of childhood asthma phenotypes.

Immun Inflamm Dis 2016 12 28;4(4):487-496. Epub 2016 Nov 28.

Channing Division of Network Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts.

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http://dx.doi.org/10.1002/iid3.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134727PMC
December 2016

Lung Metabolic Activation as an Early Biomarker of Acute Respiratory Distress Syndrome and Local Gene Expression Heterogeneity.

Anesthesiology 2016 11;125(5):992-1004

From the Departments of Anesthesia, Critical Care and Pain Medicine (T.J.W., M.T., T.W., G.M., L.F.d.R.F., J.G.V., M.F.V.M.) and Medicine (Pulmonary and Critical Care; R.S.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Medical Intensive Care Unit, Hôpital Henri Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France (N.d.P.); Department of Medicine (Pulmonary and Critical Care) (R.M.B., P.F.) and Channing Laboratory (B.R., J.-h.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and Laboratory of Histomorphometry and Lung Genomics, University of Sao Paulo, Sao Paulo, Brazil (V.C.).

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http://dx.doi.org/10.1097/ALN.0000000000001334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096592PMC
November 2016

Gene expression network analyses in response to air pollution exposures in the trucking industry.

Environ Health 2016 11 3;15(1):101. Epub 2016 Nov 3.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12940-016-0187-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093980PMC
November 2016

Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation.

PLoS One 2015 16;10(10):e0140758. Epub 2015 Oct 16.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; BWH Pulmonary Genetics Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140758PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608673PMC
June 2016

Increased expression of nuclear factor of activated T cells 1 drives IL-9-mediated allergic asthma.

J Allergy Clin Immunol 2016 06 15;137(6):1898-1902.e7. Epub 2016 Mar 15.

Laboratory of Cellular and Molecular Lung Immunology, Department of Molecular Pneumology, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.11.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889777PMC
June 2016

Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control.

J Allergy Clin Immunol 2016 05 12;137(5):1390-1397.e6. Epub 2016 Jan 12.

Department of Machine Learning, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pa.

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http://dx.doi.org/10.1016/j.jaci.2015.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860055PMC
May 2016

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Nuclear bioavailability of the glucocorticoid receptor in a pediatric asthma cohort with variable corticosteroid responsiveness.

Pediatr Res 2015 Nov 13;78(5):505-12. Epub 2015 Aug 13.

McGill University - Montreal Children's Hospital Research Institute, Montreal, Quebec, Canada.

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http://www.nature.com/articles/pr2015148
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http://dx.doi.org/10.1038/pr.2015.148DOI Listing
November 2015

Integrated microRNA and mRNA responses to acute human left ventricular ischemia.

Physiol Genomics 2015 Oct 14;47(10):455-62. Epub 2015 Jul 14.

Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.1152/physiolgenomics.00049.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593826PMC
October 2015

The metabolomics of asthma control: a promising link between genetics and disease.

Immun Inflamm Dis 2015 Sep 7;3(3):224-38. Epub 2015 May 7.

Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/iid3.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578522PMC
September 2015

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.

Hum Mol Genet 2015 Jun 12;24(11):3005-20. Epub 2015 Jan 12.

Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA Department of Theoretical Physics, Budapest University of Technology and Economics, H1111, Budapest, Hungary Center for Network Science, Central European University, Nador u. 9, 1051 Budapest, Hungary

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http://dx.doi.org/10.1093/hmg/ddv001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447811PMC
June 2015

Joint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases.

Genom Data 2014 Dec;2:202-211

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA ; Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.gdata.2014.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378545PMC
December 2014

Metabolomic derangements are associated with mortality in critically ill adult patients.

PLoS One 2014 30;9(1):e87538. Epub 2014 Jan 30.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America ; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087538PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907548PMC
September 2014

Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis.

Hum Mol Genet 2014 Sep 25;23(18):5017-24. Epub 2014 Apr 25.

Channing Division of Network Medicine and Pulmonary Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA 02115, USA

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http://dx.doi.org/10.1093/hmg/ddu191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140460PMC
September 2014

Gene expression profiling in asthma.

Adv Exp Med Biol 2014 ;795:157-81

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA,

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http://link.springer.com/10.1007/978-1-4614-8603-9_10
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http://dx.doi.org/10.1007/978-1-4614-8603-9_10DOI Listing
May 2014

Copy number variation genotyping using family information.

BMC Bioinformatics 2013 May 9;14:157. Epub 2013 May 9.

Channing Division of Network Medicine, Brigham and Women's Hospital, ,MA, USA.

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http://dx.doi.org/10.1186/1471-2105-14-157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668900PMC
May 2013

Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups.

Am J Physiol Lung Cell Mol Physiol 2012 Nov 14;303(10):L899-911. Epub 2012 Sep 14.

Departments of Human Genetics, Montreal Children’s Hospital Research Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1152/ajplung.00179.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517678PMC
November 2012

Very important pharmacogene summary for VDR.

Pharmacogenet Genomics 2012 Oct;22(10):758-63

Channing Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/FPC.0b013e328354455cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678550PMC
October 2012

Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.

J Clin Endocrinol Metab 2012 Sep 20;97(9):E1825-9. Epub 2012 Jun 20.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1210/jc.2012-1486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431565PMC
September 2012

A database of annotated promoters of genes associated with common respiratory and related diseases.

Am J Respir Cell Mol Biol 2012 Jul 1;47(1):112-9. Epub 2012 Mar 1.

Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield Clinic, Wisconsin 54449, USA.

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http://dx.doi.org/10.1165/rcmb.2011-0419OCDOI Listing
July 2012

On your marks, get set, go!

Authors:
Benjamin A Raby

Am J Respir Crit Care Med 2012 May;185(9):904-6

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http://dx.doi.org/10.1164/rccm.201202-0318EDDOI Listing
May 2012

Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses.

J Renin Angiotensin Aldosterone Syst 2011 Dec 13;12(4):564-71. Epub 2011 Apr 13.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115 , USA.

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http://dx.doi.org/10.1177/1470320311405873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444254PMC
December 2011

Finding disease variants in Mendelian disorders by using sequence data: methods and applications.

Am J Hum Genet 2011 Dec 1;89(6):701-12. Epub 2011 Dec 1.

Department of Biostatistics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234377PMC
December 2011

Identifying causal rare variants of disease through family-based analysis of Genetics Analysis Workshop 17 data set.

BMC Proc 2011 Nov 29;5 Suppl 9:S21. Epub 2011 Nov 29.

Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Building II, Boston, MA 02115, USA.

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http://dx.doi.org/10.1186/1753-6561-5-S9-S21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287856PMC
November 2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

Nat Genet 2011 Jul 31;43(9):887-92. Epub 2011 Jul 31.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.888DOI Listing
July 2011

Quantifying differential gene connectivity between disease states for objective identification of disease-relevant genes.

BMC Syst Biol 2011 May 31;5:89. Epub 2011 May 31.

Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128864PMC
May 2011

The CD4+ T-cell transcriptome and serum IgE in asthma: IL17RB and the role of sex.

BMC Pulm Med 2011 Apr 7;11:17. Epub 2011 Apr 7.

Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080837PMC
April 2011