Bengt Fadeel

Bengt Fadeel

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Bengt Fadeel

Publications by authors named "Bengt Fadeel"

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Tumor selective uptake of drug-nanodiamond complexes improves therapeutic outcome in pancreatic cancer.

Nanomedicine 2019 Mar 5. Epub 2019 Mar 5.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2019.02.020DOI Listing
March 2019

Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study.

Sci Rep 2019 Mar 13;9(1):4366. Epub 2019 Mar 13.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-019-40579-6DOI Listing
March 2019

Structure and function analysis of the aminophospholipid translocase TAT-1.

J Cell Sci 2019 Feb 28;132(5). Epub 2019 Feb 28.

Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80309, USA

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.227660
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http://dx.doi.org/10.1242/jcs.227660DOI Listing
February 2019

Hide and Seek: Nanomaterial Interactions With the Immune System.

Authors:
Bengt Fadeel

Front Immunol 2019 1;10:133. Epub 2019 Feb 1.

Nanosafety and Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2019.00133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367956PMC
February 2019

Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death.

Cell Death Discov 2019 8;5:65. Epub 2019 Feb 8.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41420-019-0146-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368547PMC
February 2019

Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment.

FASEB J 2019 Jan 18:fj201801741R. Epub 2019 Jan 18.

Department of Women's and Children's Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden.

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https://www.fasebj.org/doi/10.1096/fj.201801741R
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http://dx.doi.org/10.1096/fj.201801741RDOI Listing
January 2019

JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia.

J Leukoc Biol 2018 Dec 14;104(6):1199-1213. Epub 2018 Aug 14.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/JLB.4A0118-030RRDOI Listing
December 2018

Degradation of Single-Layer and Few-Layer Graphene by Neutrophil Myeloperoxidase.

Angew Chem Int Ed Engl 2018 Sep 1;57(36):11722-11727. Epub 2018 Aug 1.

University of Strasbourg, CNRS, Immunology, Immunopathology and Therapeutic Chemistry, UPR 3572, 67000, Strasbourg, France.

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http://dx.doi.org/10.1002/anie.201806906DOI Listing
September 2018

HAX-1 overexpression in multiple myeloma is associated with poor survival.

Br J Haematol 2018 Jun 19. Epub 2018 Jun 19.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/bjh.15430DOI Listing
June 2018

Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution.

Chemosphere 2018 Apr 29;196:482-493. Epub 2017 Dec 29.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2017.12.182DOI Listing
April 2018

RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells.

Sci Rep 2018 Apr 27;8(1):6668. Epub 2018 Apr 27.

Unit of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-018-25085-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923294PMC
April 2018

Nitric Oxide Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery.

Adv Healthc Mater 2018 Mar 15;7(6):e1700916. Epub 2018 Jan 15.

Nanosafety & Nanomedicine Laboratory-NNL, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1002/adhm.201700916DOI Listing
March 2018

Cytokine Profiling of Primary Human Macrophages Exposed to Endotoxin-Free Graphene Oxide: Size-Independent NLRP3 Inflammasome Activation.

Adv Healthc Mater 2018 Feb 21;7(4). Epub 2017 Dec 21.

Nanosafety & Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1002/adhm.201700815DOI Listing
February 2018

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic.

Nanoscale 2018 Jan;10(3):1180-1188

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://xlink.rsc.org/?DOI=C7NR03552G
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http://dx.doi.org/10.1039/c7nr03552gDOI Listing
January 2018

Nanoparticles and innate immunity: new perspectives on host defence.

Semin Immunol 2017 12 30;34:33-51. Epub 2017 Aug 30.

School of Medicine, Pharmacy and Health, Durham University, Queen's Campus, Stockton-on-Tees TS17 6BH, UK; Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S10445323173004
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http://dx.doi.org/10.1016/j.smim.2017.08.013DOI Listing
December 2017

Cytotoxicity screening and cytokine profiling of nineteen nanomaterials enables hazard ranking and grouping based on inflammogenic potential.

Nanotoxicology 2017 Aug 17;11(6):809-826. Epub 2017 Aug 17.

a Division of Molecular Toxicology , Institute of Environmental Medicine, Karolinska Institutet , Stockholm , Sweden.

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http://dx.doi.org/10.1080/17435390.2017.1363309DOI Listing
August 2017

[Nano for better or worse: opportunities and risks with nanotechnology].

Authors:
Bengt Fadeel

Lakartidningen 2017 07 4;114. Epub 2017 Jul 4.

Karolinska Institutet - Stockholm, Sweden Karolinska Institutet - Institute of Environmental Medicine Stockholm, Sweden.

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July 2017

Graphene and the Immune System: A Romance of Many Dimensions.

Front Immunol 2017 13;8:673. Epub 2017 Jun 13.

Nanosafety and Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2017.00673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468375PMC
June 2017

Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: Cytotoxicity or inflammation?

Chemosphere 2017 Mar 24;171:671-680. Epub 2016 Dec 24.

Exposure Assessment Branch/NIOSH/CDC, Morgantown, WV, USA; Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2016.12.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459363PMC
March 2017

Macrophage activation status determines the internalization of mesoporous silica particles of different sizes: Exploring the role of different pattern recognition receptors.

Biomaterials 2017 03 27;121:28-40. Epub 2016 Dec 27.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.12.029DOI Listing
March 2017

Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab.

Arthritis Res Ther 2017 03 7;19(1):44. Epub 2017 Mar 7.

Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14186, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13075-017-1241-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341184PMC
March 2017

Programmed cell clearance: From nematodes to humans.

Biochem Biophys Res Commun 2017 01 2;482(3):491-497. Epub 2016 Dec 2.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 17177, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476906PMC
January 2017

Editorial: Special issue on cell death in honor of Sten Orrenius.

Biochem Biophys Res Commun 2017 01 3;482(3):383. Epub 2017 Feb 3.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2016.12.159DOI Listing
January 2017

Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids.

Biochem Biophys Res Commun 2017 01 3;482(3):482-490. Epub 2017 Feb 3.

Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.bbrc.2016.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319735PMC
January 2017

Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk.

Toxicol Appl Pharmacol 2016 May 22;299:101-11. Epub 2015 Dec 22.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2015.12.014DOI Listing
May 2016

Biological interactions of carbon-based nanomaterials: From coronation to degradation.

Nanomedicine 2016 Feb 17;12(2):333-51. Epub 2015 Dec 17.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2015.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789123PMC
February 2016

Nanodrugs to target articular cartilage: An emerging platform for osteoarthritis therapy.

Nanomedicine 2016 Feb 18;12(2):255-68. Epub 2015 Dec 18.

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.nano.2015.09.013DOI Listing
February 2016

Single-Walled Carbon Nanotubes Inhibit the Cytochrome P450 Enzyme, CYP3A4.

Sci Rep 2016 Feb 22;6:21316. Epub 2016 Feb 22.

Nanosafety &Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1038/srep21316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761960PMC
February 2016

Systems biology in nanosafety research.

Authors:
Bengt Fadeel

Nanomedicine (Lond) 2015 ;10(7):1039-41

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http://dx.doi.org/10.2217/nnm.15.17DOI Listing
January 2016

Keeping it real: The importance of material characterization in nanotoxicology.

Biochem Biophys Res Commun 2015 Dec 15;468(3):498-503. Epub 2015 Jul 15.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2015.06.178DOI Listing
December 2015

Editorial: Brave new world - Focus on nanomedicine.

Biochem Biophys Res Commun 2015 Dec 28;468(3):409-10. Epub 2015 Oct 28.

Nanomedicine & Nanosafety Laboratory (NNL), Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.10.135DOI Listing
December 2015

Freewheelin' scientists: citing Bob Dylan in the biomedical literature.

BMJ 2015 Dec 14;351:h6505. Epub 2015 Dec 14.

Institute of Environmental Medicine, Karolinska Institutet.

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http://dx.doi.org/10.1136/bmj.h6505DOI Listing
December 2015

It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system.

Eur J Pharm Biopharm 2015 Sep 11;95(Pt A):3-12. Epub 2015 Mar 11.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Nobels väg 13, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2015.03.007DOI Listing
September 2015

Meeting report: BBRC Symposium on Trends in Biochemistry and Biophysics.

Biochem Biophys Res Commun 2015 Sep;465(1):v-vii

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September 2015

Recent nanomedicine articles of outstanding interest.

Nanomedicine (Lond) 2015 Jul;10(12):1859-61

Nanosafety & Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2217/nnm.15.79DOI Listing
July 2015

Next-generation sequencing reveals low-dose effects of cationic dendrimers in primary human bronchial epithelial cells.

ACS Nano 2015 Jan 30;9(1):146-63. Epub 2014 Dec 30.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, and ‡Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet , Stockholm, Sweden.

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http://dx.doi.org/10.1021/nn5061783DOI Listing
January 2015

Enzymatic 'stripping' and degradation of PEGylated carbon nanotubes.

Nanoscale 2014 Dec 7;6(24):14686-90. Epub 2014 Nov 7.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Nobels väg 13, Stockholm 171 77, Sweden.

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http://dx.doi.org/10.1039/c4nr03604bDOI Listing
December 2014

Targeted uptake of folic acid-functionalized iron oxide nanoparticles by ovarian cancer cells in the presence but not in the absence of serum.

Nanomedicine 2014 Oct 31;10(7):1421-31. Epub 2014 Jan 31.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2014.01.006DOI Listing
October 2014

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines.

Part Fibre Toxicol 2014 Sep 2;11:41. Epub 2014 Sep 2.

Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://particleandfibretoxicology.biomedcentral.com/articles
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http://dx.doi.org/10.1186/s12989-014-0041-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237954PMC
September 2014

Exploring the anti-apoptotic role of HAX-1 versus BCL-XL in cytokine-dependent bone marrow-derived cells from mice.

FEBS Lett 2014 Aug 6;588(17):2921-7. Epub 2014 Jun 6.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.05.042DOI Listing
August 2014

Classification framework for graphene-based materials.

Angew Chem Int Ed Engl 2014 Jul 10;53(30):7714-8. Epub 2014 Jun 10.

Laboratory for Materials-Biology Interactions Empa, Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, CH-9014 St. Gallen (Switzerland).

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http://dx.doi.org/10.1002/anie.201403335DOI Listing
July 2014

Extracellular entrapment and degradation of single-walled carbon nanotubes.

Nanoscale 2014 Jun;6(12):6974-83

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1039/c3nr06047kDOI Listing
June 2014

Proapoptotic effects of the novel proteasome inhibitor b-AP15 on multiple myeloma cells and natural killer cells.

Exp Hematol 2014 Mar 27;42(3):172-82. Epub 2013 Nov 27.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2013.11.010DOI Listing
March 2014

Bortezomib and IL-12 produce synergetic anti-multiple myeloma effects with reduced toxicity to natural killer cells.

Anticancer Drugs 2014 Mar;25(3):282-8

Departments of aOncology bHematology, Qilu Hospital, Shandong University cDepartment of Hematology, The Second Hospital of Shandong University, Jinan, People's Republic of China dChildhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska University Hospital eDivision of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1097/CAD.0000000000000058DOI Listing
March 2014

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release.

Part Fibre Toxicol 2014 Feb 17;11:11. Epub 2014 Feb 17.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1186/1743-8977-11-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933429PMC
February 2014

Dexamethasone differentially regulates Bcl-2 family proteins in human proliferative chondrocytes: role of pro-apoptotic Bid.

Toxicol Lett 2014 Jan 27;224(2):196-200. Epub 2013 Oct 27.

Department of Women's and Children's Health, Pediatric Endocrinology Unit, Astrid Lindgren Children's Hospital, Karolinska Institutet, Stockholm 171 76, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2013.10.020DOI Listing
January 2014

Research highlights: Highlights from the last year in nanomedicine.

Nanomedicine (Lond) 2014 Jan;9(1):17-20

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2217/nnm.13.188DOI Listing
January 2014

Mechanisms of carbon nanotube-induced toxicity: focus on pulmonary inflammation.

Adv Drug Deliv Rev 2013 Dec 7;65(15):2087-97. Epub 2013 Jun 7.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.addr.2013.05.012DOI Listing
December 2013

Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro.

Cell Biochem Biophys 2013 Nov;67(2):461-76

Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), M/L 2015, 1095 Willowdale Road, Morgantown, WV, 26505, USA.

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http://dx.doi.org/10.1007/s12013-012-9367-9DOI Listing
November 2013

Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential.

Toxicology 2013 Nov 16;313(1):15-23. Epub 2012 Nov 16.

CSIRO Materials Science and Engineering, Clayton, Australia; Monash Institute of Pharmaceutical Science, Parkville, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0300483X120039
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http://dx.doi.org/10.1016/j.tox.2012.11.005DOI Listing
November 2013

Nanotoxicology.

Toxicology 2013 Nov 21;313(1):1-2. Epub 2013 Sep 21.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.tox.2013.09.010DOI Listing
November 2013

Macrophage clearance of neutrophil extracellular traps is a silent process.

J Immunol 2013 Sep 31;191(5):2647-56. Epub 2013 Jul 31.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.1300436DOI Listing
September 2013

Bridge over troubled waters: understanding the synthetic and biological identities of engineered nanomaterials.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2013 Mar-Apr;5(2):111-29. Epub 2013 Jan 17.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/wnan.1206DOI Listing
August 2013

AIF and Scythe (Bat3) regulate phosphatidylserine exposure and macrophage clearance of cells undergoing Fas (APO-1)-mediated apoptosis.

PLoS One 2012 15;7(10):e47328. Epub 2012 Oct 15.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047328PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471829PMC
July 2013

Interactions of engineered nanoparticles with organs protected by internal biological barriers.

Small 2013 May 23;9(9-10):1557-72. Epub 2012 Oct 23.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1002/smll.201201463DOI Listing
May 2013

Geoengineering: perilous particles.

Science 2013 May;340(6132):548-9

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http://dx.doi.org/10.1126/science.340.6132.548-bDOI Listing
May 2013

Programmed cell death: molecular mechanisms and implications for safety assessment of nanomaterials.

Acc Chem Res 2013 Mar 21;46(3):733-42. Epub 2012 Jun 21.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1021/ar300020bDOI Listing
March 2013

Broaden the discussion.

Nat Nanotechnol 2013 Feb;8(2):71

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http://dx.doi.org/10.1038/nnano.2013.2DOI Listing
February 2013

Ovarian failure in HAX1-deficient patients: is there a gender-specific difference in pubertal development in severe congenital neutropenia or Kostmann disease?

Acta Paediatr 2013 Jan;102(1):78-82

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://doi.wiley.com/10.1111/apa.12050
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http://dx.doi.org/10.1111/apa.12050DOI Listing
January 2013

Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells.

Mol Pharmacol 2013 Jan 23;83(1):245-55. Epub 2012 Oct 23.

Division of Molecular Toxicology, Institute of Environmental Medicine, Nobels väg 13, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1124/mol.112.080788DOI Listing
January 2013

Clear and present danger? Engineered nanoparticles and the immune system.

Authors:
Bengt Fadeel

Swiss Med Wkly 2012 26;142:w13609. Epub 2012 Jun 26.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://doi.emh.ch/smw.2012.13609
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http://dx.doi.org/10.4414/smw.2012.13609DOI Listing
October 2012

Towards the clinic: intelligent design of nanomedicines for cancer treatment.

Nanomedicine (Lond) 2012 Sep;7(9):1293

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2217/nnm.12.113DOI Listing
September 2012

Perinatal nanomedicine: dendrimer-based therapy for neuroinflammatory disorders.

Nanomedicine (Lond) 2012 Sep;7(9):1294

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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September 2012

The importance of size: nanomedicine for delivery of anticancer drugs in solid tumors.

Nanomedicine (Lond) 2012 Sep;7(9):1294-5

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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September 2012

DNA origami: self-assembled nucleic acid nanoparticles for siRNA delivery.

Nanomedicine (Lond) 2012 Sep;7(9):1295

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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September 2012

Trimodal imaging of brain tumors using multifunctional nanoparticles.

Nanomedicine (Lond) 2012 Sep;7(9):1295-6

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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September 2012

Incidence of severe congenital neutropenia in Sweden and risk of evolution to myelodysplastic syndrome/leukaemia.

Br J Haematol 2012 Aug 25;158(3):363-9. Epub 2012 May 25.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1365-2141.2012.09171.xDOI Listing
August 2012

Safety assessment of nanomaterials: implications for nanomedicine.

J Control Release 2012 Jul 25;161(2):403-8. Epub 2012 Jan 25.

Swedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jconrel.2012.01.027DOI Listing
July 2012

Ablation of the pro-apoptotic protein Bax protects mice from glucocorticoid-induced bone growth impairment.

PLoS One 2012 19;7(3):e33168. Epub 2012 Mar 19.

Pediatric Endocrinology Unit, Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033168PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307731PMC
July 2012

Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.

Cancer Lett 2012 Jun 20;319(2):232-241. Epub 2012 Jan 20.

Department of Oncology, Clinical Sciences, Lund University, Lund, Sweden; CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835120004
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http://dx.doi.org/10.1016/j.canlet.2012.01.015DOI Listing
June 2012

Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress.

Toxicol Appl Pharmacol 2012 Jun 6;261(2):121-33. Epub 2012 Apr 6.

Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.taap.2012.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686133PMC
June 2012

Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos.

Part Fibre Toxicol 2012 Apr 10;9:10. Epub 2012 Apr 10.

Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.

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http://dx.doi.org/10.1186/1743-8977-9-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379937PMC
April 2012

Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers.

Biomaterials 2012 Mar 15;33(7):1970-81. Epub 2011 Dec 15.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.biomaterials.2011.11.054DOI Listing
March 2012

Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis.

FEBS Lett 2012 Mar 26;586(6):747-52. Epub 2012 Jan 26.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.febslet.2012.01.034DOI Listing
March 2012