Aziz Zaanan

Aziz Zaanan

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Aziz Zaanan

Publications by authors named "Aziz Zaanan"

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Exploring the best treatment options for BRAF-mutant metastatic colon cancer.

Br J Cancer 2019 Sep 29;121(6):434-442. Epub 2019 Jul 29.

Sorbonne Paris-Cité, Paris Descartes University, Assistance Publique Hôpitaux de Paris (APHP), Gastro-enterology and GI Oncology Department, Georges Pompidou European Hospital, Paris, France.

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http://dx.doi.org/10.1038/s41416-019-0526-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738120PMC
September 2019

Plasma clearance of RAS mutation under therapeutic pressure is a rare event in metastatic colorectal cancer.

Int J Cancer 2019 Aug 31. Epub 2019 Aug 31.

Centre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, F-75006, Paris, France.

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http://dx.doi.org/10.1002/ijc.32657DOI Listing
August 2019

[Microsatellite instability and cancer: from genomic instability to personalized medicine].

Med Sci (Paris) 2019 Jun-Jul;35(6-7):535-543. Epub 2019 Jul 5.

Sorbonne Université, UPMC Univ Paris 06, Inserm, UMRS 938, Équipe Instabilité des microsatellites et cancer, Centre de recherche Saint Antoine, 75012 Paris, France Équipe labellisée par la Ligue nationale ontre le cancer et SIRIC CURAMUS, APHP.6.

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http://dx.doi.org/10.1051/medsci/2019093DOI Listing
July 2019

Integration of elicited expert information via a power prior in Bayesian variable selection: Application to colon cancer data.

Stat Methods Med Res 2019 Apr 9:962280219841082. Epub 2019 Apr 9.

1 INSERM U1138, University Paris Descartes, Sorbonne University, Paris, France.

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http://dx.doi.org/10.1177/0962280219841082DOI Listing
April 2019

Comparison of three lymph node staging schemes for predicting the outcome in patients with small bowel adenocarcinoma: A population-based cohort and international multicentre cohort study.

EBioMedicine 2019 Mar 26;41:276-285. Epub 2019 Feb 26.

Department of Rheumatology and Immunology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.02.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443578PMC
March 2019

[Predictive and prognostic value of MSI phenotype in adjuvant colon cancer: Who and how to treat?]

Bull Cancer 2019 Feb 4;106(2):129-136. Epub 2018 Dec 4.

European Georges Pompidou Hospital, AP-HP, Department of Gastroenterology and Digestive Oncology, Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2018.10.011DOI Listing
February 2019

How to better select patients with advanced gastric cancer for immunotherapy.

Transl Gastroenterol Hepatol 2019 31;4. Epub 2019 Jan 31.

Department of Gastroenterology and Digestive Oncology, European Georges Pompidou Hospital, AP-HP, Paris, France.

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http://dx.doi.org/10.21037/tgh.2019.01.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378262PMC
January 2019

Role of circulating tumor DNA in the management of patients with colorectal cancer.

Clin Res Hepatol Gastroenterol 2018 10 5;42(5):396-402. Epub 2018 Apr 5.

INSERM UMR-S1147, CNRS SNC5014, Paris Descartes University, Equipe labellisée Ligue Nationale contre le cancer, Paris, France; Department of Gastroenterology and Digestive Oncology, European Georges Pompidou Hospital, AP-HP, Paris Descartes University, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2018.03.002DOI Listing
October 2018

Colorectal Cancer: Why Does Side Matter?

Drugs 2018 Jun;78(8):789-798

Department of Gastroenterology and Digestive Oncology, Assistance Publique-Hôpitaux De Paris, Hôpital Européen Georges Pompidou, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1007/s40265-018-0921-7DOI Listing
June 2018

Impact of an optimized colonoscopic screening program for patients with Lynch syndrome: 6-year results of a specialized French network.

Therap Adv Gastroenterol 2018 27;11:1756284818775058. Epub 2018 May 27.

Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service d'hépato-gastro-entérologie et d'endoscopie, Paris, France.

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http://dx.doi.org/10.1177/1756284818775058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974573PMC
May 2018

Trastuzumab in Combination with FOLFIRI in Patients with Advanced HER2-Positive Gastro-Esophageal Adenocarcinoma: A Retrospective Multicenter AGEO Study.

Target Oncol 2018 02;13(1):107-112

Department of Gastroenterology and Digestive Oncology, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, 20 rue Leblanc, 75015, Paris, France.

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http://dx.doi.org/10.1007/s11523-017-0531-4DOI Listing
February 2018

Early Evaluation of Circulating Tumor DNA as Marker of Therapeutic Efficacy in Metastatic Colorectal Cancer Patients (PLACOL Study).

Clin Cancer Res 2017 Sep 2;23(18):5416-5425. Epub 2017 Jun 2.

INSERM UMR-S1147, CNRS SNC5014; Paris Descartes University, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3155DOI Listing
September 2017

Small Bowel Adenocarcinoma.

Gastroenterol Clin North Am 2016 09;45(3):447-57

Translational Cancer Therapeutics department, The Beatson West of Scotland Cancer Centre, University of Glasgow, 1053 Great Western Road, Glasgow G12 0YN, UK.

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http://dx.doi.org/10.1016/j.gtc.2016.04.004DOI Listing
September 2016

Efficacy of Adjuvant Chemotherapy in Colon Cancer With Microsatellite Instability: A Large Multicenter AGEO Study.

J Natl Cancer Inst 2016 Jul 1;108(7). Epub 2016 Feb 1.

Affiliations of authors: Department of Gastroenterology (DT, GS, CS), Department of Medical Oncology (AF), and Department of Molecular Oncology (LKT), Poitiers University Hospital , Poitiers , France ; Laboratoire Inflammation, Tissus Epithéliaux et Cytokines (LITEC) - EA 4331, Poitiers University , Poitiers (DT, CS); Methodology and Quality of Life in Oncology Unit, Besançon University Hospital , Besançon , France (GM); Department of Gastroenterology, Ambroise Paré Hospital , Boulogne-Billancourt , France (IT); Department of Gastroenterology (TL) and Department of Biochemistry (JCP), Tours University Hospital , Tours , France , UMR GICC CNRS 7292, Tours François Rabelais University, Tours (TL); Paris Descartes University, Cochin Hospital , Paris , France (RC); Department of Gastroenterology (TA) and Department of Medical Oncology (CDG), Avicenne Hospital , Bobigny , France ; Department of Gastroenterology, Bordeaux Nord Aquitaine Clinic , Bordeaux , France (CL); Department of Gastroenterology, Jean Mermoz Lyon Hospital , Lyon , France (PA); Department of Gastroenterology, Nantes University Hospital , Nantes , France (EC, TMB); Department of Gastroenterology, Rouen University Hospital , Rouen , France (DS, PM); Department of Medical Oncology, Saint-Antoine Hospital , Paris , France (TB); Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, APHP , Paris , France (JT, AZ); Paris Descartes University, Sorbonne Paris Cité , Paris , France (RC, JT, AZ).

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http://dx.doi.org/10.1093/jnci/djv438DOI Listing
July 2016

Prognostic Effect of BRAF and KRAS Mutations in Patients With Stage III Colon Cancer Treated With Leucovorin, Fluorouracil, and Oxaliplatin With or Without Cetuximab: A Post Hoc Analysis of the PETACC-8 Trial.

JAMA Oncol 2016 May;2(5):643-653

Centre de Recherché UMR-S 1147, Médecine Personnalisée, Pharmacogénomique, Optimisation Thérapeutique, Institut National de la Santé et de la Recherche Médicale, Paris, France6Paris Descartes University, Department of Biology, European Georges Pompidou Ho.

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http://dx.doi.org/10.1001/jamaoncol.2015.5225DOI Listing
May 2016

Advanced small bowel adenocarcinoma: Molecular characteristics and therapeutic perspectives.

Clin Res Hepatol Gastroenterol 2016 Apr 4;40(2):154-60. Epub 2015 Nov 4.

Department of Gastroenterology and Digestive Oncology, European Georges Pompidou Hospital, AP-HP, 20, rue Leblanc, 75015 Paris, France; UMR-S 1147, Inserm, Paris, France; Paris Descartes University, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2015.09.008DOI Listing
April 2016

Efficacy of modern chemotherapy and prognostic factors in patients with ovarian metastases from gastric cancer: A retrospective AGEO multicentre study.

Dig Liver Dis 2016 Apr 29;48(4):441-5. Epub 2015 Dec 29.

Paris Descartes University, Sorbonne Paris Cité, Faculty of Medicine, Paris, France; Gastroenterology and Digestive Oncology Department, Georges Pompidou European Hospital, APHP, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2015.12.012DOI Listing
April 2016

Implications of mismatch repair-deficient status on management of early stage colorectal cancer.

J Gastrointest Oncol 2015 Dec;6(6):676-84

Mayo Clinic and Mayo Cancer Center, Rochester, MN 55905, USA.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2015.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671842PMC
December 2015

The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.

J Biol Chem 2015 Sep 5;290(39):23838-49. Epub 2015 Aug 5.

From the Departments of Medicine and Oncology, Gastroenterology Research Unit, and the Mayo Clinic Cancer Center and

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http://dx.doi.org/10.1074/jbc.M115.657833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583008PMC
September 2015

Microsatellite instability testing and its role in the management of colorectal cancer.

Curr Treat Options Oncol 2015 Jul;16(7):30

Mayo Clinic and Mayo Cancer Center, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s11864-015-0348-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594190PMC
July 2015

Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.

Mol Cancer Res 2015 Apr 29;13(4):659-69. Epub 2014 Dec 29.

Department of Medicine, GI Research Unit, Mayo Clinic and Mayo Cancer Center, Rochester, Minnesota. Department of Oncology, GI Research Unit, Mayo Clinic and Mayo Cancer Center, Rochester, Minnesota.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
Publisher Site
http://dx.doi.org/10.1158/1541-7786.MCR-14-0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398608PMC
April 2015

Sarcopenia is linked to treatment toxicity in patients with metastatic colorectal cancer.

Nutr Cancer 2014 7;66(4):583-9. Epub 2014 Apr 7.

a Service de Gastro-entérologie et Endoscopie Digestive, Hôpital Européen Georges Pompidou, Paris, France; Association des Gastroentérologues Oncologues, France; Assistance-publique Hôpitaux de Paris, Paris, France, and Université Paris-Descartes, Sorbonne Paris-Cité , France.

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http://dx.doi.org/10.1080/01635581.2014.894103DOI Listing
December 2014

Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in , and in Patients with Lymph Node-Positive Colon Cancer.

Curr Colorectal Cancer Rep 2014 Sep;10(3):346-353

Mayo Clinic and Mayo Cancer Center, Rochester, Minnesota, United States of America, 200 First St SW, Rochester, MN 55905. Telephone: 507-255-5713.

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http://dx.doi.org/10.1007/s11888-014-0237-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224319PMC
September 2014

ERBB2 gene as a potential therapeutic target in small bowel adenocarcinoma.

Eur J Cancer 2014 Jul 2;50(10):1740-1746. Epub 2014 May 2.

Université Paris Descartes, Sorbone Paris Cité, Paris, France; Inserm UMR-S775 Bases Moléculaires de la réponse aux xénobiotiques, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2014.04.007DOI Listing
July 2014

Sustained response with gemcitabine plus Nab-paclitaxel after folfirinox failure in metastatic pancreatic cancer: report of an effective new strategy.

Clin Res Hepatol Gastroenterol 2014 Apr 18;38(2):e23-6. Epub 2014 Feb 18.

Service d'hépatogastro-entérologie et d'oncologie digestive, université Paris Descartes, Sorbonne Paris-Cité, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2014.01.005DOI Listing
April 2014

Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.

Dig Liver Dis 2014 Feb 21;46(2):97-104. Epub 2013 Jun 21.

Oncology Unit, Saint Antoine Hospital, APHP, Paris, France.

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http://dx.doi.org/10.1016/j.dld.2013.04.013DOI Listing
February 2014

Immunity and squamous cell carcinoma of the anus: epidemiological, clinical and therapeutic aspects.

Clin Res Hepatol Gastroenterol 2014 Feb 8;38(1):18-23. Epub 2013 Aug 8.

Service d'Hépatogastro-entérologie et d'oncologie digestive, Hôpital Européen Georges-Pompidou, Université Paris Descartes, 20, rue Leblanc, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2013.07.002DOI Listing
February 2014

[MET signalling pathway and its therapeutic implications in gastrointestinal cancers].

Bull Cancer 2014 Jan;101(1):25-30

Hôpital européen Georges-Pompidou, AP-HP, Service de gastroentérologie et oncologie digestive, 20, rue Leblanc, 75015 Paris, France.

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http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/bd
Publisher Site
http://dx.doi.org/10.1684/bdc.2013.1870DOI Listing
January 2014

Chemosensitivity in ovarian metastases from gastric cancer: a case series.

Clin Res Hepatol Gastroenterol 2013 Jun 9;37(3):289-95. Epub 2012 Nov 9.

Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, University of Paris Descartes, 20, rue Leblanc, 75015 Paris, France.

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http://dx.doi.org/10.1016/j.clinre.2012.09.007DOI Listing
June 2013

Gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma: a large multicenter AGEO study.

J Hepatol 2013 Jan 16;58(1):81-8. Epub 2012 Sep 16.

Service d'Hépato-Gastroentérologie et Oncologie digestive, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2012.09.006DOI Listing
January 2013

Brain metastases from pancreatic adenocarcinoma.

BMJ Case Rep 2009 27;2009. Epub 2009 Feb 27.

Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Gastroentérologie, 20 rue Leblanc, 75015 Paris, France.

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http://dx.doi.org/10.1136/bcr.08.2008.0620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028083PMC
November 2011

Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications.

Cell Oncol (Dordr) 2011 Jun 12;34(3):155-76. Epub 2011 Apr 12.

INSERM, UMR_S, Centre de Recherche Saint-Antoine, Paris, France.

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http://dx.doi.org/10.1007/s13402-011-0024-xDOI Listing
June 2011

Medical treatment of pancreatic cancer: new hopes after 10 years of gemcitabine.

Clin Res Hepatol Gastroenterol 2011 May 23;35(5):364-74. Epub 2011 Mar 23.

Service d'oncologie digestive, hôpital européen Georges-Pompidou, AP-HP, université Paris V, 20, rue Leblanc, 75015 Paris, France.

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http://dx.doi.org/10.1016/j.clinre.2011.02.002DOI Listing
May 2011