Axel Facius

Axel Facius

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Axel Facius

Axel Facius

Publications by authors named "Axel Facius"

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16Publications

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What Can Be Learned From Crowdsourced Population Asparagus Urinary Odor Kinetics?

CPT Pharmacometrics Syst Pharmacol 2019 06 23;8(6):407-414. Epub 2019 Apr 23.

Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1002/psp4.12401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617763PMC
June 2019

Use of a 4-week up-titration regimen of roflumilast in patients with severe COPD.

Int J Chron Obstruct Pulmon Dis 2018 6;13:813-822. Epub 2018 Mar 6.

Department of Clinical Sciences, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.2147/COPD.S154012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846760PMC
September 2018

Modeling and Simulation of Pivotal Clinical Trials Using Linked Models for Multiple Endpoints in Chronic Obstructive Pulmonary Disease With Roflumilast.

J Clin Pharmacol 2017 08 17;57(8):1042-1052. Epub 2017 Apr 17.

Takeda Pharmaceuticals International GmbH, Glattpark-Opfikon (Zürich), Switzerland.

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http://dx.doi.org/10.1002/jcph.885DOI Listing
August 2017

Population pharmacokinetic meta-analysis to bridge ferumoxytol plasma pharmacokinetics across populations.

Clin Pharmacokinet 2015 Apr;54(4):385-95

Takeda Pharmaceuticals International GmbH, Thurgauerstrasse 130, 8152, Glattpark-Opfikon (Zürich), Switzerland,

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http://dx.doi.org/10.1007/s40262-014-0203-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368844PMC
April 2015

Application of population pharmacokinetic modeling to explore the impact of alternative roflumilast dosing regimens on tolerability.

Int J Clin Pharmacol Ther 2013 Nov;51(11):832-6

Department of Pharmacometrics, Takeda Pharmaceuticals International GmbH, Zurich, Switzerland.

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http://dx.doi.org/10.5414/cp201906DOI Listing
November 2013

An innovative phase I population pharmacokinetic approach to investigate the pharmacokinetics of an intranasal fentanyl spray in healthy subjects.

Int J Clin Pharmacol Ther 2013 Jun;51(6):495-508

Takeda Pharmaceuticals International GmbH, Zürich, Switzerland.

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http://dx.doi.org/10.5414/CP201867DOI Listing
June 2013

Bioinformatics challenges in proteomics.

Comb Chem High Throughput Screen 2005 Dec;8(8):705-15

Institut für Bioinformatik, GSF -- Forschungszentrum für Umwelt und Gesundheit, Neuherberg, Germany.

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http://dx.doi.org/10.2174/138620705774962454DOI Listing
December 2005

Super paramagnetic clustering of protein sequences.

BMC Bioinformatics 2005 Apr 1;6:82. Epub 2005 Apr 1.

GSF National Research Center for Environment and Health, Institute for Bioinformatics, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-6-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084344PMC
April 2005

Gene selection from microarray data for cancer classification--a machine learning approach.

Comput Biol Chem 2005 Feb;29(1):37-46

Institute for Bioinformatics, German Research Center for Environment and Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.compbiolchem.2004.11.001DOI Listing
February 2005

PRIME: a graphical interface for integrating genomic/proteomic databases.

Proteomics 2005 Jan;5(1):76-80

Institute for Bioinformatics, GSF Research Center, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1002/pmic.200400862DOI Listing
January 2005