Dr. ASM Alamgir, PhD - IEDCR - PSO and Coordinator, One Health Laboratory

Dr. ASM Alamgir

PhD

IEDCR

PSO and Coordinator, One Health Laboratory

DHAKA, DHAKA | Bangladesh

Additional Specialties: Virology

Dr. ASM Alamgir, PhD - IEDCR - PSO and Coordinator, One Health Laboratory

Dr. ASM Alamgir

PhD

Introduction

Primary Affiliation: IEDCR - DHAKA, DHAKA , Bangladesh

Additional Specialties:

Research Interests:

Publications

21Publications

410Reads

30Profile Views

250PubMed Central Citations

An epidemic of chikungunya in northwestern Bangladesh in 2011.

PLoS One 2019 11;14(3):e0212218. Epub 2019 Mar 11.

Infectious Diseases Division (IDD), icddr,b, Dhaka, Bangladesh.

Background: In November 2011, a government hospital physician in Shibganj sub-district of Bangladesh reported a cluster of patients with fever and joint pain or rash. A multi-disciplinary team investigated to characterize the outbreak; confirm the cause; and recommend control and prevention measures.

Methods: Shibganj's residents with new onset of fever and joint pain or rash between 1 September and 15 December 2011 were defined as chikungunya fever (CHIKF) suspect cases. To estimate the attack rate, we identified 16 outpatient clinics in 16 selected wards across 16 unions in Shibganj and searched for suspect cases in the 80 households nearest to each outpatient clinic. One suspect case from the first 30 households in each ward was invited to visit the nearest outpatient clinic for clinical assessment and to provide a blood sample for laboratory testing and analyses.

Results: We identified 1,769 CHIKF suspect cases from among 5,902 residents surveyed (30%). Their median age was 28 (IQR:15-42) years. The average attack rate in the sub-district was 30% (95% CI: 27%-33%). The lowest attack rate was found in children <5 years (15%). Anti-CHIKV IgM antibodies were detected by ELISA in 78% (264) of the 338 case samples tested. In addition to fever, predominant symptoms of serologically-confirmed cases included joint pain (97%), weakness (54%), myalgia (47%), rash (42%), itching (37%) and malaise (31%). Among the sero-positive patients, 79% (209/264) sought healthcare from outpatient clinics. CHIKV was isolated from two cases and phylogenetic analyses of full genome sequences placed these viruses within the Indian Ocean Lineage (IOL). Molecular analysis identified mutations in E2 and E1 glycoproteins and contained the E1 A226V point mutation.

Conclusion: The consistently high attack rate by age groups suggested recent introduction of chikungunya in this community. Mosquito control efforts should be enhanced to reduce the risk of continued transmission and to improve global health security.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212218PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411100PMC
March 2019
18 Reads
3.234 Impact Factor

Outbreak of mass sociogenic illness in a school feeding program in northwest Bangladesh, 2010.

PLoS One 2013 14;8(11):e80420. Epub 2013 Nov 14.

Centre for Communicable Diseases (CCD), icddr,b, Dhaka, Bangladesh ; Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080420PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828262PMC
February 2015
29 Reads
3 Citations
3.234 Impact Factor

Bronchiolitis outbreak caused by respiratory syncytial virus in southwest Bangladesh, 2010.

Int J Infect Dis 2012 Dec 29;16(12):e866-71. Epub 2012 Aug 29.

Centre for Communicable Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijid.2012.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629474PMC
December 2012
7 Reads
1 Citation
2.330 Impact Factor

Influenza-associated mortality in 2009 in four sentinel sites in Bangladesh.

Bull World Health Organ 2012 Apr;90(4):272-8

International Centre for Diarrhoeal Disease Research, Bangladesh, Saheed Tajuddin Ahmed Sarani, Mohakhalai, Dhaka-1212, Bangladesh.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2471/BLT.11.095653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324868PMC
April 2012
17 Reads
15 Citations
5.090 Impact Factor

Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh.

Am J Trop Med Hyg 2012 Jan;86(1):58-64

International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4269/ajtmh.2012.11-0190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247110PMC
January 2012
8 Reads
10 Citations
2.700 Impact Factor

Hepatitis B among pregnant women attending health care facilities in rural Bangladesh.

Southeast Asian J Trop Med Public Health 2011 Nov;42(6):1410-3

Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

View Article

Download full-text PDF

Source
November 2011
7 Reads
0.550 Impact Factor

Co-circulation of G1, G2 and G9 rotaviruses in hospitalized patients in Bangladesh during 2006-2009.

Hum Vaccin 2011 Sep 1;7(9):929-33. Epub 2011 Sep 1.

Laboratory of Virology, ICDDR,B: International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka, Bangladesh.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/hv.7.9.15988DOI Listing
September 2011
4 Reads
1 Citation
3.643 Impact Factor

Precise identification of endogenous proviruses of NFS/N mice participating in recombination with moloney ecotropic murine leukemia virus (MuLV) to generate polytropic MuLVs.

J Virol 2005 Apr;79(8):4664-71

Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, 903 S. 4th St., Hamilton, MT 59840, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.79.8.4664-4671.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069548PMC
April 2005
7 Reads
12 Citations
4.440 Impact Factor

Antigenic subclasses of polytropic murine leukemia virus (MLV) isolates reflect three distinct groups of endogenous polytropic MLV-related sequences in NFS/N mice.

J Virol 2003 Oct;77(19):10327-38

Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC228382PMC
http://dx.doi.org/10.1128/jvi.77.19.10327-10338.2003DOI Listing
October 2003
2 Reads
12 Citations
4.440 Impact Factor

Phylogenetic analysis of influenza C virus nonstructural (NS) protein genes and identification of the NS2 protein.

J Gen Virol 2000 Aug;81(Pt 8):1933-40

Department of Bacteriology, Yamagata University School of Medicine, Iida-Nishi, Yamagata 990-9585, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/0022-1317-81-8-1933DOI Listing
August 2000
7 Reads
15 Citations
3.183 Impact Factor