Publications by authors named "Ashraf S Ibrahim"

100Publications

Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections.

J Fungi (Basel) 2020 Oct 22;6(4). Epub 2020 Oct 22.

The Lundquist Institute for Biomedical Innovation at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA 90502, USA.

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October 2020

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis.

mBio 2020 06 2;11(3). Epub 2020 Jun 2.

Division of Infectious Diseases, The Lundquist Institute for Biomedical Innovation, Harbor-University of California Los Angeles Medical Center, Torrance, California, USA

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June 2020

Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection.

Antimicrob Agents Chemother 2020 07 22;64(8). Epub 2020 Jul 22.

The Lundquist Institute for Biomedical Innovations at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, California, USA

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July 2020

Design and synthesis of new drugs inhibitors of Candida albicans hyphae and biofilm formation by upregulating the expression of TUP1 transcription repressor gene.

Eur J Pharm Sci 2020 May 6;148:105327. Epub 2020 Apr 6.

Division of Infectious Diseases, The Lundquist Institute for Biomedical Innovations, Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA 90502, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address:

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May 2020

Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus.

Antimicrob Agents Chemother 2020 05 21;64(6). Epub 2020 May 21.

The Lundquist Institute for Biomedical Innovations at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, California, USA

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May 2020

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis.

Antimicrob Agents Chemother 2020 02 21;64(3). Epub 2020 Feb 21.

Division of Infectious Diseases, The Lundquist Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and St. John's Cardiovascular Research Center, Torrance, California, USA

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February 2020

Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.

Lancet Infect Dis 2019 12 5;19(12):e405-e421. Epub 2019 Nov 5.

Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

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December 2019

The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.

PLoS Pathog 2019 08 5;15(8):e1007460. Epub 2019 Aug 5.

Division of Infectious Disease, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance, California, United States of America.

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August 2019

Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.

Sci Adv 2019 06 12;5(6):eaaw1327. Epub 2019 Jun 12.

Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA.

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June 2019

NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice.

Sci Rep 2019 04 17;9(1):6194. Epub 2019 Apr 17.

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.

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April 2019

Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS.

Molecules 2019 Jan 22;24(3). Epub 2019 Jan 22.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA, 90509, USA.

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January 2019

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis.

Antimicrob Agents Chemother 2019 02 29;63(2). Epub 2019 Jan 29.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and St. John's Cardiovascular Research Center, Torrance, California, USA

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February 2019

Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens.

mSphere 2018 10 31;3(5). Epub 2018 Oct 31.

Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles (UCLA) Medical Center, Torrance, California, USA

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October 2018

PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis.

J Clin Microbiol 2018 10 25;56(10). Epub 2018 Sep 25.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA

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October 2018

The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.

PLoS Pathog 2018 05 10;14(5):e1007056. Epub 2018 May 10.

Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles (UCLA) Medical Center, Torrance, California, United States of America.

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May 2018

Validation of the Endothelial Cell Receptor GRP78 in a Case of Rhinocerebral Mucormycosis.

Antimicrob Agents Chemother 2018 05 26;62(5). Epub 2018 Apr 26.

Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany

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May 2018

Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens.

Molecules 2017 Dec 20;22(12). Epub 2017 Dec 20.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90509, USA.

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December 2017

The mucormycete-host interface.

Curr Opin Microbiol 2017 Dec 4;40:40-45. Epub 2017 Nov 4.

School of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK. Electronic address:

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December 2017

Molecular mechanisms of mucormycosis-The bitter and the sweet.

PLoS Pathog 2017 08 3;13(8):e1006408. Epub 2017 Aug 3.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor, University of California Los Angeles (UCLA) Medical Center and the St. John's Cardiovascular Research Center, Torrance, California, United States of America.

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August 2017

Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Antimicrob Agents Chemother 2017 09 24;61(9). Epub 2017 Aug 24.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and St. John's Cardiovascular Research Center, Torrance, California, USA

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September 2017

Assessment of herbal drugs for promising anti-Candida activity.

BMC Complement Altern Med 2017 May 8;17(1):257. Epub 2017 May 8.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA, USA.

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May 2017

Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis.

Antimicrob Agents Chemother 2017 05 24;61(5). Epub 2017 Apr 24.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and St. John's Cardiovascular Research Center, Torrance, California, USA

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May 2017

Aspergillus fumigatus CalA binds to integrin αβ and mediates host cell invasion.

Nat Microbiol 2016 Nov 14;2:16211. Epub 2016 Nov 14.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA.

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November 2016

Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis.

J Antimicrob Chemother 2017 02 24;72(2):462-466. Epub 2016 Oct 24.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA, USA

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February 2017

Statin Concentrations Below the Minimum Inhibitory Concentration Attenuate the Virulence of Rhizopus oryzae.

J Infect Dis 2016 07 16;214(1):114-21. Epub 2016 Mar 16.

Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.

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July 2016

Molecular epidemiology and characterization of multiple drug-resistant (MDR) clinical isolates of Acinetobacter baumannii.

Int J Infect Dis 2015 Dec 27;41:42-9. Epub 2015 Oct 27.

Division of Adult Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, 1124 West Carson St., St. John's Cardiovascular Research Center, Torrance, CA 90502, USA; David Geffen School of Medicine at UCLA, Los Angeles, California, USA. Electronic address:

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December 2015

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Antimicrob Agents Chemother 2015 Dec 14;59(12):7815-7. Epub 2015 Sep 14.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and St. John's Cardiovascular Research Center, Torrance, California, USA David Geffen School of Medicine at UCLA, Los Angeles, California, USA

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December 2015

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus.

Infect Immun 2015 Nov 8;83(11):4427-37. Epub 2015 Sep 8.

Division of Molecular Medicine, Harbor-UCLA Medical Center, Torrance, California, USA Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance, California, USA St. John's Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

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November 2015

Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine.

PLoS Pathog 2015 May 14;11(5):e1004842. Epub 2015 May 14.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance, California, United States of America; David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America.

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May 2015

The genome sequence of four isolates from the family Lichtheimiaceae.

Pathog Dis 2015 Jul 9;73(5). Epub 2015 Apr 9.

Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

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July 2015

Iron starvation induces apoptosis in Rhizopus oryzae in vitro.

Virulence 2015 ;6(2):121-6

a Department of Infectious Diseases ; Infection Control and Employee Health; The University of Texas M D Anderson Cancer Center ; Houston , TX USA.

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January 2016

Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.

Proc Natl Acad Sci U S A 2014 Dec 8;111(51):E5555-63. Epub 2014 Dec 8.

Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095; Divisions of Infectious Diseases and St. John's Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502; and.

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December 2014

Human Fungal Pathogens of Mucorales and Entomophthorales.

Cold Spring Harb Perspect Med 2014 Nov 6;5(4). Epub 2014 Nov 6.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710.

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November 2014

Host-iron assimilation: pathogenesis and novel therapies of mucormycosis.

Authors:
Ashraf S Ibrahim

Mycoses 2014 Dec 1;57 Suppl 3:13-7. Epub 2014 Sep 1.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and the St. John's Cardiovascular Research Center, Torrance, CA, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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December 2014

Heat-killed yeast protects diabetic ketoacidotic-steroid treated mice from pulmonary mucormycosis.

Vaccine 2014 Jun 6;32(29):3573-6. Epub 2014 May 6.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA, United States; St. John's Cardiovascular Research Center, Torrance, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States. Electronic address:

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June 2014

Isavuconazole therapy protects immunosuppressed mice from mucormycosis.

Antimicrob Agents Chemother 2014 3;58(4):2450-3. Epub 2014 Feb 3.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles Medical Center, and St. John's Cardiovascular Research Center, Torrance, California, USA.

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November 2014

Update on mucormycosis pathogenesis.

Curr Opin Infect Dis 2013 Dec;26(6):508-15

aDivision of Infectious Diseases, Harbor-University of California Los Angeles Medical Center bSt. John's Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance cDavid Geffen School of Medicine at UCLA, Los Angeles, California dDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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December 2013

NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response.

Vaccine 2013 Nov 21;31(47):5549-56. Epub 2013 Sep 21.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and the St. John's Cardiovascular Research Center, Torrance, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States. Electronic address:

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November 2013

Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis.

Antimicrob Agents Chemother 2013 Jul 6;57(7):3340-7. Epub 2013 May 6.

Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, California, USA.

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July 2013

Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata.

Infect Immun 2013 Jul 29;81(7):2528-35. Epub 2013 Apr 29.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.

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July 2013

Risk factors for mortality in patients with mucormycosis.

Med Mycol 2012 Aug 21;50(6):611-8. Epub 2012 Mar 21.

Division of General Internal Medicine, Los Angeles Biomedical Research Institute, Harbor-University of California Los Angeles (UCLA) Medical Center, Los Angeles, CA, USA.

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August 2012

Diabetic murine models for Acinetobacter baumannii infection.

J Antimicrob Chemother 2012 Jun 2;67(6):1439-45. Epub 2012 Mar 2.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

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June 2012

Pathogenesis of mucormycosis.

Clin Infect Dis 2012 Feb;54 Suppl 1:S16-22

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, University of California-Los Angeles, 1124 W Carson St., Torrance, CA 90502, USA.

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February 2012

Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection.

PLoS One 2012 10;7(1):e29446. Epub 2012 Jan 10.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, California, United States of America.

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May 2012

Luminescent-activated transfected killer cells to monitor leukocyte trafficking during systemic bacterial and fungal infection.

J Infect Dis 2012 Jan 28;205(2):337-47. Epub 2011 Nov 28.

Department of Medicine, Division of General Internal Medicine, Los Angeles Biomedical Research Institute, Harbor-University of California at Los Angeles Medical Center, Torrance, CA, USA.

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January 2012

Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis.

PLoS One 2011 10;6(10):e25909. Epub 2011 Oct 10.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.

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February 2012

The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial.

J Antimicrob Chemother 2012 Mar 20;67(3):715-22. Epub 2011 Sep 20.

Division of General Internal Medicine, Los Angeles Biomedical Research Institute, Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA, USA.

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March 2012

Host cell invasion in mucormycosis: role of iron.

Authors:
Ashraf S Ibrahim

Curr Opin Microbiol 2011 Aug 30;14(4):406-11. Epub 2011 Jul 30.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, United States.

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August 2011

Recent advances in the treatment of mucormycosis.

Curr Infect Dis Rep 2010 Nov;12(6):423-9

The Division of General Internal Medicine, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles (UCLA) Medical Center, 1124 West Carson Street, Torrance, CA, 90502, USA,

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November 2010

Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins.

Antimicrob Agents Chemother 2011 Apr 24;55(4):1768-70. Epub 2011 Jan 24.

Los Angeles Biomedical Research Institute, Division of Infectious Diseases, Harbor-UCLA Medical Center, 1124 West Carson St., St. John's Cardiovascular Research Center, Torrance, CA 90502, USA.

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April 2011

Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis.

Mol Microbiol 2010 Nov 27;78(4):1038-54. Epub 2010 Sep 27.

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

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November 2010

The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis.

Mol Microbiol 2010 Aug 1;77(3):587-604. Epub 2010 Jun 1.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center, Torrance, CA, USA.

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August 2010

The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.

J Clin Invest 2010 Jun 17;120(6):1914-24. Epub 2010 May 17.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA.

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June 2010

Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target.

J Infect Dis 2010 Jun;201(11):1718-28

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA.

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June 2010

Safety and efficacy of activated transfected killer cells for neutropenic fungal infections.

J Infect Dis 2010 Jun;201(11):1708-17

Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-University of California at Los Angeles (UCLA) Medical Center, 1124 West Carson Street, Torrance, CA 90502, USA.

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June 2010

Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice.

PLoS Pathog 2009 Dec 24;5(12):e1000703. Epub 2009 Dec 24.

The Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.

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December 2009

Immunological reactivity of blood from healthy humans to the rAls3p-N vaccine protein.

J Infect Dis 2010 Feb;201(3):473-7

Divisions of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-University of California at Los Angeles (UCLA) Medical Center, USA.

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February 2010

The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis.

J Antimicrob Chemother 2010 Feb 26;65(2):289-92. Epub 2009 Nov 26.

Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles Medical Center, Torrance, CA 90502, USA.

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February 2010

Recent advances in the management of mucormycosis: from bench to bedside.

Clin Infect Dis 2009 Jun;48(12):1743-51

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, 1124 West Carson St., RB2, Torrance, CA 90502, USA.

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June 2009

Safety and outcomes of open-label deferasirox iron chelation therapy for mucormycosis.

Antimicrob Agents Chemother 2009 Jul 11;53(7):3122-5. Epub 2009 May 11.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 West Carson St., Torrance, CA 90502, USA.

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July 2009

Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment.

Curr Opin Infect Dis 2008 Dec;21(6):620-5

Division of Infectious Diseases, Harbor-UCLA Medical Center, 1124 West Carson St, RB2, Torrance, CA 90502, USA.

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December 2008

Posaconazole mono- or combination therapy for treatment of murine zygomycosis.

Antimicrob Agents Chemother 2009 Feb 20;53(2):772-5. Epub 2008 Oct 20.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles Medical Center, Torrance, 90502, USA.

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February 2009

Economic burden of mucormycosis in the United States: can a vaccine be cost-effective?

Med Mycol 2009 ;47(6):592-600

Division of Infectious Diseases, Harbor-University of California at Los Angeles Medical Center, and the Los Angeles Biomedical Research Institute, Torrance, California 90502, USA.

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March 2010

The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus.

Infect Immun 2008 Oct 21;76(10):4574-80. Epub 2008 Jul 21.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor, University of California at Los Angeles Medical Center, Torrance, California 90502, USA.

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October 2008

Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis.

Clin Infect Dis 2008 Aug;47(3):364-71

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor, University of California at Los Angeles Medical Center, Torrance, CA, USA.

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August 2008

Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity.

J Infect Dis 2008 Apr;197(7):967-71

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles, Medical Center, Torrance, CA 90502, USA.

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April 2008

Comparison of lipid amphotericin B preparations in treating murine zygomycosis.

Antimicrob Agents Chemother 2008 Apr 28;52(4):1573-6. Epub 2008 Jan 28.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California--Los Angeles Medical Center, Torrance, CA 90502, USA.

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April 2008

Combination echinocandin-polyene treatment of murine mucormycosis.

Antimicrob Agents Chemother 2008 Apr 22;52(4):1556-8. Epub 2008 Jan 22.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

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April 2008

Considerable differences in vaccine immunogenicities and efficacies related to the diluent used for aluminum hydroxide adjuvant.

Clin Vaccine Immunol 2008 Mar 9;15(3):582-4. Epub 2008 Jan 9.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson St., Torrance, CA 90502, USA.

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March 2008

Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans.

Eukaryot Cell 2008 Mar 4;7(3):483-92. Epub 2008 Jan 4.

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson St., Torrance, CA 90502, USA.

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March 2008

The iron chelator deferasirox protects mice from mucormycosis through iron starvation.

J Clin Invest 2007 Sep;117(9):2649-57

Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA.

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September 2007

Native and modified lactate dehydrogenase expression in a fumaric acid producing isolate Rhizopus oryzae 99-880.

Curr Genet 2007 Jul 6;52(1):23-33. Epub 2007 Jun 6.

Bioproducts and Biocatalysis Research Unit, National Center for Agricultural Utilization Research, USDA, Agricultural Research Service, 1815 N. University Street, Peoria, IL 61604, USA.

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July 2007

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells.

PLoS Biol 2007 Mar;5(3):e64

Department of Medicine, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, United States of America.

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March 2007

Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts.

J Leukoc Biol 2007 Mar 8;81(3):632-41. Epub 2006 Dec 8.

Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

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March 2007

Comparison of antifungal treatments for murine fusariosis.

J Antimicrob Chemother 2006 Nov 14;58(5):973-9. Epub 2006 Sep 14.

David Geffen School of Medicine at UCLA Los Angeles, CA, USA.

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November 2006

Deferiprone iron chelation as a novel therapy for experimental mucormycosis.

J Antimicrob Chemother 2006 Nov 23;58(5):1070-3. Epub 2006 Aug 23.

David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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November 2006

Plasmids for expression of heterologous proteins in Rhizopus oryzae.

Arch Microbiol 2006 Jul 28;186(1):41-50. Epub 2006 Jun 28.

Fermentation Biotechnology Research Unit, National Center for Agricultural Utilization Research, USDA, Agricultural Research Service, 1815 N. University St., Peoria, IL 61604, USA.

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July 2006

Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis.

J Infect Dis 2006 Jul 6;194(2):256-60. Epub 2006 Jun 6.

Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance, Torrance, CA 90502, USA.

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July 2006