Publications by authors named "Arie B Brinkman"

33Publications

Terminal keratinocyte differentiation in vitro is associated with a stable DNA methylome.

Exp Dermatol 2020 Jul 17. Epub 2020 Jul 17.

Department of Dermatology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center (Radboudumc), Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/exd.14153DOI Listing
July 2020

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2019 02;566(7742):E1

Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

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http://www.nature.com/articles/s41586-019-0883-2
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http://dx.doi.org/10.1038/s41586-019-0883-2DOI Listing
February 2019

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.

Cell Stem Cell 2019 01 21;24(1):123-137.e8. Epub 2018 Nov 21.

Department of Molecular Biology, Faculty of Science, Radboud University, Radboud Institute for Molecular Life Sciences (RIMLS), 6525GA Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.10.017DOI Listing
January 2019

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2016 06 2;534(7605):47-54. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature17676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910866PMC
June 2016

Genome-wide binding of MBD2 reveals strong preference for highly methylated loci.

PLoS One 2014 13;9(6):e99603. Epub 2014 Jun 13.

Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099603PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057170PMC
October 2015

Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells.

Cell Stem Cell 2013 Sep 11;13(3):360-9. Epub 2013 Jul 11.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences NCMLS, Radboud University, 6525GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.stem.2013.06.002DOI Listing
September 2013

Dynamic binding of RBPJ is determined by Notch signaling status.

Genes Dev 2013 May;27(9):1059-71

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen 6525 GA, the Netherlands.

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http://dx.doi.org/10.1101/gad.211912.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656323PMC
May 2013

Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues.

Epigenetics 2012 Dec 18;7(12):1355-67. Epub 2012 Oct 18.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.

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http://dx.doi.org/10.4161/epi.22562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528691PMC
December 2012

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk.

Genome Res 2012 Jun 30;22(6):1128-38. Epub 2012 Mar 30.

Radboud University, Nijmegen Center for Molecular Life Sciences, Department of Molecular Biology, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1101/gr.133728.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371717PMC
June 2012

Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis.

Genome Res 2011 Aug 2;21(8):1313-27. Epub 2011 Jun 2.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, 6500 Nijmegen, The Netherlands.

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http://dx.doi.org/10.1101/gr.114843.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149498PMC
August 2011

Whole-genome DNA methylation profiling using MethylCap-seq.

Methods 2010 Nov 11;52(3):232-6. Epub 2010 Jun 11.

Radboud University, Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Faculty of Science, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ymeth.2010.06.012DOI Listing
November 2010

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

Mol Biosyst 2010 Sep 4;6(9):1700-6. Epub 2010 Jun 4.

Department of Physiological Chemistry and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1039/c004108dDOI Listing
September 2010

PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.

Cancer Cell 2010 Feb;17(2):173-85

Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, the Netherlands.

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http://dx.doi.org/10.1016/j.ccr.2009.12.042DOI Listing
February 2010

DNA methylation immediately adjacent to active histone marking does not silence transcription.

Nucleic Acids Res 2007 3;35(3):801-11. Epub 2007 Jan 3.

Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkl1014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807972PMC
March 2007

Molecular characterization of a conserved archaeal copper resistance (cop) gene cluster and its copper-responsive regulator in Sulfolobus solfataricus P2.

Microbiology (Reading) 2006 Jul;152(Pt 7):1969-1979

Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands.

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http://dx.doi.org/10.1099/mic.0.28724-0DOI Listing
July 2006

Histone modification patterns associated with the human X chromosome.

EMBO Rep 2006 Jun 28;7(6):628-34. Epub 2006 Apr 28.

Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, NCMLS M850/3.79, Radboud University, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/sj.embor.7400686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479594PMC
June 2006

Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family.

Nucleic Acids Res 2006 9;34(5):1439-49. Epub 2006 Mar 9.

Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

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http://dx.doi.org/10.1093/nar/gkl009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401507PMC
April 2006

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

Mol Cell Biol 2006 Feb;26(3):843-51

Department of Molecular Biology, NCMLS M850/3.79, Radboud University, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/MCB.26.3.843-851.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347035PMC
February 2006

Targeted discovery tools: proteomics and chromatin immunoprecipitation-on-chip.

BJU Int 2005 Dec;96 Suppl 2:16-22

Nijmegen Center for Molecular Life Sciences, Department of Molecular Biology, Radboud University Nijmegen, Geert Grooteplein 30, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2005.05942.xDOI Listing
December 2005

The Lrp family of transcriptional regulators.

Mol Microbiol 2003 Apr;48(2):287-94

Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL-6307 CT Wageningen, The Netherlands.

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http://dx.doi.org/10.1046/j.1365-2958.2003.03442.xDOI Listing
April 2003

A novel ligand-binding domain involved in regulation of amino acid metabolism in prokaryotes.

J Biol Chem 2002 Oct 23;277(40):37464-8. Epub 2002 Jul 23.

Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL-6307 CT Wageningen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M206063200DOI Listing
October 2002

The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability.

J Biol Chem 2002 Aug 31;277(33):29537-49. Epub 2002 May 31.

Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Hesselink van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M203528200DOI Listing
August 2002