Dr. Arati Sharma, MDS  - BP Koirala  Institute  of  Health  Sciences

Dr. Arati Sharma

MDS

BP Koirala Institute of Health Sciences

Dharan | Nepal

Main Specialties: Dentistry

Additional Specialties: MDS (PROSTHODONTICS )

ORCID logohttps://orcid.org/0000-0002-8530-5975

Dr. Arati Sharma, MDS  - BP Koirala  Institute  of  Health  Sciences

Dr. Arati Sharma

MDS

Introduction

Primary Affiliation: BP Koirala Institute of Health Sciences - Dharan , Nepal

Specialties:

Additional Specialties:

Metrics

Number of Publications

41

Publications

Number of Profile Views

189

Profile Views

Number of Article Reads

456

Reads

Number of Citations

3

Citations

Education

Feb 2015
BPKIHS
MDS

Experience

Feb 2015
BPKIHS
Assistant Professor

Top co-authors

Gavin P Robertson
Gavin P Robertson

The Pennsylvania State University College of Medicine

33
Subbarao V Madhunapantula
Subbarao V Madhunapantula

Pennsylvania State University College of Medicine

11
Raghavendra Gowda
Raghavendra Gowda

The Pennsylvania State University College of Medicine

10
Shantu Amin
Shantu Amin

Penn State College of Medicine

8
Mark Kester
Mark Kester

Penn State College of Medicine

7
Dhimant Desai
Dhimant Desai

Penn State College of Medicine

7
Omer F Kuzu
Omer F Kuzu

Penn State College of Medicine

6
Sung Jin Huh
Sung Jin Huh

The Pennsylvania State University College of Medicine

6
Mitchell Cheung
Mitchell Cheung

The Pennsylvania State College of Medicine

4
Cheng Dong
Cheng Dong

University Park

3

Publications

41Publications

456Reads

3PubMed Central Citations

Preferred Source and Perceived Need of More Information about Dental Implants by the Undergraduate Dental Students of Nepal: All Nepal Survey.

Int J Dent 2018 11;2018:6794682. Epub 2018 Mar 11.

Department of Prosthodontics, CODS, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

View Article
March 2018
67 Reads

Identification of WEE1 as a target to make AKT inhibition more effective in melanoma.

Cancer Biol Ther 2018 01 30;19(1):53-62. Epub 2017 Nov 30.

a The Pennsylvania State University College of Medicine , Department of Pharmacology , Hershey , PA.

View Article
January 2018
9 Reads
3 Citations
3.070 Impact Factor

Cost-effectiveness of pazopanib versus sunitinib for metastatic renal cell carcinoma in the United Kingdom.

PLoS One 2017 21;12(6):e0175920. Epub 2017 Jun 21.

Research, Policy Analysis Inc. (PAI), Brookline, Massachusetts, United States of America.

View Article
October 2017
26 Reads
3.230 Impact Factor

Improving pharmacological targeting of AKT in melanoma.

Cancer Lett 2017 09 11;404:29-36. Epub 2017 Jul 11.

Department of Pharmacology, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA; Department of Pathology, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA; Department of Dermatology, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA; Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA; The Melanoma Center, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA. Electronic address:

View Article
September 2017
15 Reads
5.620 Impact Factor

Electrochemical immunosensor based on poly (3,4-ethylenedioxythiophene) modified with gold nanoparticle to detect aflatoxin B.

Mater Sci Eng C Mater Biol Appl 2017 Jul 18;76:802-809. Epub 2017 Mar 18.

Analytical Chemistry Division, CSIR-North East Institute of Science & Technology, Academy of Scientific and Innovative Research, Jorhat 785006, Assam, India. Electronic address:

View Article
July 2017
15 Reads
3.090 Impact Factor

Nanoparticle-Based Celecoxib and Plumbagin for the Synergistic Treatment of Melanoma.

Mol Cancer Ther 2017 03 21;16(3):440-452. Epub 2016 Dec 21.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania.

View Article
March 2017
25 Reads
5.680 Impact Factor

Synergistic inhibitory effects of Celecoxib and Plumbagin on melanoma tumor growth.

Cancer Lett 2017 01 18;385:243-250. Epub 2016 Oct 18.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; Department of Dermatology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; The Penn State Melanoma Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; Penn State Melanoma Therapeutics Program, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states; Foreman Foundation for Melanoma Research, The Pennsylvania State University College of Medicine, Hershey, PA 17033, United states. Electronic address:

View Article
January 2017
4 Reads
5.620 Impact Factor

Current State of Animal (Mouse) Modeling in Melanoma Research.

Cancer Growth Metastasis 2015 6;8(Suppl 1):81-94. Epub 2015 Oct 6.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA, USA.

View Article
October 2015
9 Reads

Fabrication of Closed Hollow Bulb Obturator Using Thermoplastic Resin Material.

Case Rep Dent 2015 27;2015:504561. Epub 2015 Sep 27.

Department of Prosthodontics & Crown and Bridge, College of Dental Surgery, BPKIHS, Dharan, Nepal.

View Article
October 2015
9 Reads

Nanolipolee-007, a novel nanoparticle-based drug containing leelamine for the treatment of melanoma.

Mol Cancer Ther 2014 Oct 31;13(10):2328-40. Epub 2014 Jul 31.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. The Penn State Melanoma Center, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Penn State Melanoma Therapeutics Program, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Foreman Foundation for Melanoma Research, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Department of Dermatology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania.

View Article
October 2014
4 Reads
5.680 Impact Factor

Targeting multiple key signaling pathways in melanoma using leelamine.

Mol Cancer Ther 2014 Jul 31;13(7):1679-89. Epub 2014 Mar 31.

Authors' Affiliations: Departments of Pharmacology, Pathology, Dermatology, and Surgery, Penn State Hershey Melanoma Center, Penn State Melanoma Therapeutics Program, The Foreman Foundation for Melanoma Research, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania

View Article
July 2014
9 Reads
5.680 Impact Factor

Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.

Mol Cancer Ther 2014 Jul 31;13(7):1690-703. Epub 2014 Mar 31.

Authors' Affiliations: Departments of Pharmacology, Pathology, Dermatology, and Surgery; Penn State Hershey Melanoma Center; Penn State Melanoma Therapeutics Program; and The Foreman Foundation for Melanoma Research, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania

View Article
July 2014
4 Reads
5.680 Impact Factor

Identification of glycogen synthase kinase 3α as a therapeutic target in melanoma.

Pigment Cell Melanoma Res 2013 Nov 19;26(6):886-99. Epub 2013 Sep 19.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA, USA; Penn State Melanoma Center, The Pennsylvania State University College of Medicine, Hershey, PA, USA; Penn State Melanoma Therapeutics Program, The Pennsylvania State University College of Medicine, Hershey, PA, USA.

View Article
November 2013
10 Reads
4.620 Impact Factor

Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis.

Mol Ther 2013 Oct 18;21(10):1919-29. Epub 2013 Jun 18.

Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

View Article
October 2013
18 Reads
6.230 Impact Factor

Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.

Am J Pathol 2013 Apr 12;182(4):1151-62. Epub 2013 Feb 12.

Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
April 2013
7 Reads
4.590 Impact Factor

Realizing the clinical potential of cancer nanotechnology by minimizing toxicologic and targeted delivery concerns.

Cancer Res 2012 Nov 8;72(22):5663-8. Epub 2012 Nov 8.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
November 2012
5 Reads
9.330 Impact Factor

Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems.

Expert Opin Drug Metab Toxicol 2012 Jan 19;8(1):47-69. Epub 2011 Nov 19.

The Pennsylvania State University College of Medicine, Department of Pharmacology, R130, 500 University Drive, Hershey, PA 17033, USA.

View Article
January 2012
6 Reads
2.830 Impact Factor

eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206.

Cancer Res 2011 Apr 9;71(7):2654-63. Epub 2011 Feb 9.

Department of Pharmacology and The Penn State Hershey Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

View Article
April 2011
8 Reads
9.330 Impact Factor

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

Cancer Prev Res (Phila) 2011 Feb 19;4(2):248-58. Epub 2010 Nov 19.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article
February 2011
6 Reads

Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide.

Stem Cells Dev 2009 Jan-Feb;18(1):55-65

Department of Pharmacology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 17033-0850, USA.

View Article
October 2010
5 Reads
3.730 Impact Factor

Robust activation of the human but not mouse telomerase gene during the induction of pluripotency.

FASEB J 2010 Aug 30;24(8):2702-15. Epub 2010 Mar 30.

Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

View Article
August 2010
22 Reads
5.040 Impact Factor

Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development.

Cancer Res 2010 Jul 7;70(14):6071-82. Epub 2010 Jul 7.

Departments of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
July 2010
7 Reads
9.330 Impact Factor

Macrophage inhibitory cytokine-1 regulates melanoma vascular development.

Am J Pathol 2010 Jun 29;176(6):2948-57. Epub 2010 Apr 29.

The Pennsylvania State College of Medicine, Department of Pharmacology, Hershey, PA 17033, USA.

View Article
June 2010
4 Reads
4.590 Impact Factor

Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer.

Bioorg Med Chem Lett 2010 Mar 22;20(6):2038-43. Epub 2009 Sep 22.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article
March 2010
10 Reads
2.420 Impact Factor

Targeting Akt3 signaling in malignant melanoma using isoselenocyanates.

Clin Cancer Res 2009 Mar 10;15(5):1674-85. Epub 2009 Feb 10.

Department of Pharmacology, The Foreman Foundation for Melanoma Research, Hershey, Pennsylvania 17033, USA.

View Article
March 2009
7 Reads
8.720 Impact Factor

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.

J Med Chem 2008 Dec;51(24):7820-6

Department of Pharmacology, Penn State Hershey College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
December 2008
7 Reads
5.450 Impact Factor

Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.

Cancer Res 2008 Sep;68(18):7638-49

Department of Pharmacology, The Pennsylvania State University, Hershey, Pennsylvania 17033, USA.

View Article
September 2008
19 Reads
9.330 Impact Factor

Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.

Cancer Res 2008 May;68(9):3429-39

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article
May 2008
4 Reads
9.330 Impact Factor

PBISe, a novel selenium-containing drug for the treatment of malignant melanoma.

Mol Cancer Ther 2008 May;7(5):1297-308

Department of Pharmacology, The Pennsylvania State University College of Medicine, 500 University Drive, R130, Hershey, PA 17033, USA.

View Article
May 2008
3 Reads
5.680 Impact Factor

Models of melanoma metastasis: using a transient siRNA-based protein inhibition strategy in mice to validate the functional relevance of pharmacological agents.

Curr Protoc Pharmacol 2007 Sep;Chapter 14:Unit 14.6

The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania, USA.

View Article
September 2007
7 Reads

Targeting mutant (V600E) B-Raf in melanoma interrupts immunoediting of leukocyte functions and melanoma extravasation.

Cancer Res 2007 Jun;67(12):5814-20

Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

View Article
June 2007
8 Reads
9.330 Impact Factor

PRAS40 deregulates apoptosis in malignant melanoma.

Cancer Res 2007 Apr;67(8):3626-36

Department of Pharmacology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA.

View Article
April 2007
5 Reads
9.330 Impact Factor

Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.

Cancer Res 2006 Aug;66(16):8200-9

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article
August 2006
8 Reads
9.330 Impact Factor

Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

Clin Cancer Res 2005 May;11(9):3465-74

Department of Pharmacology, Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
May 2005
7 Reads
8.720 Impact Factor

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors.

Cancer Res 2005 Mar;65(6):2412-21

Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey 17033, USA.

View Article
March 2005
5 Reads
9.330 Impact Factor

Deregulated Akt3 activity promotes development of malignant melanoma.

Cancer Res 2004 Oct;64(19):7002-10

Department of Pharmacology, The Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
October 2004
5 Reads
9.330 Impact Factor

Loss of PTEN promotes tumor development in malignant melanoma.

Cancer Res 2003 Jun;63(11):2881-90

Department of Pharmacology, The Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA.

View Article
June 2003
6 Reads
9.330 Impact Factor

Top co-authors

Gavin P Robertson
Gavin P Robertson

The Pennsylvania State University College of Medicine

33
Subbarao V Madhunapantula
Subbarao V Madhunapantula

Pennsylvania State University College of Medicine

11
Raghavendra Gowda
Raghavendra Gowda

The Pennsylvania State University College of Medicine

10
Shantu Amin
Shantu Amin

Penn State College of Medicine

8
Mark Kester
Mark Kester

Penn State College of Medicine

7
Dhimant Desai
Dhimant Desai

Penn State College of Medicine

7
Omer F Kuzu
Omer F Kuzu

Penn State College of Medicine

6
Sung Jin Huh
Sung Jin Huh

The Pennsylvania State University College of Medicine

6
Mitchell Cheung
Mitchell Cheung

The Pennsylvania State College of Medicine

4
Cheng Dong
Cheng Dong

University Park

3