Publications by authors named "Antonio Uccelli"

100Publications

The role of B cells in Multiple Sclerosis and related disorders.

Ann Neurol 2020 Oct 9. Epub 2020 Oct 9.

Department of Neurology, UCSF Weill Institute for Neuroscience, University of California, San Francisco, USA.

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http://dx.doi.org/10.1002/ana.25927DOI Listing
October 2020

COVID-19-related and not related Guillain-Barré syndromes share the same management pitfalls during lock down: The experience of Liguria region in Italy.

J Neurol Sci 2020 Sep 2;418:117114. Epub 2020 Sep 2.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy; IRCCS, Ospedale Policlinico San Martino, Genova, Italy.

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http://dx.doi.org/10.1016/j.jns.2020.117114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462770PMC
September 2020

Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS.

Ann Clin Transl Neurol 2020 Aug 23. Epub 2020 Aug 23.

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, NeuroCure Cluster of Excellence, Berlin, Germany.

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http://dx.doi.org/10.1002/acn3.51148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480923PMC
August 2020

Tailoring B cell depletion therapy in MS according to memory B cell monitoring.

Neurol Neuroimmunol Neuroinflamm 2020 Sep 4;7(5). Epub 2020 Aug 4.

From the Department of Neuroscience (G.N.), Ospedale Policlinico San Martino-IRCCS; Department of Health Sciences (DISSAL) (F.B., I.M., L.R., M.S.), University of Genova, Italy; Ospedale A. Micone (S.F., P.G.), Genova; Department of Neuroscience (F.T., N.B., G.B., C.L., M.C., A.L., E.C., G.M.), Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova; Ospedale Policlinico San Martino-IRCCS (F.T., N.B., L.R., A.L., E.C., M.S., M.I., A.U.), Genova, Italy; Ospedale San Paolo (D.C.), Savona; Autoimmunity Laboratory DiMI (G.P.), University of Genova, Italy; Monsignor Luigi Novarese Rehabilitation Center (C.S.), Moncrivello, Vercelli; Istituti Clinici Scientifici Maugeri (G.M.), IRCCS, Pavia; and Department of Neuroscience (M.I., A.U.), Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) and Center of Excellence for Biomedical Research (CEBR), University of Genova, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413707PMC
September 2020

Neuroaxonal Degeneration in Patients With Multiple Sclerosis: An Optical Coherence Tomography and in Vivo Corneal Confocal Microscopy Study.

Cornea 2020 Oct;39(10):1221-1226

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Eye Clinic, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1097/ICO.0000000000002396DOI Listing
October 2020

Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer's mice.

Cell Death Differ 2020 Jul 23. Epub 2020 Jul 23.

Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, via Mario Negri 2, 20156, Milan, Italy.

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http://dx.doi.org/10.1038/s41418-020-0592-2DOI Listing
July 2020

A randomized, placebo-controlled, phase 2 trial of laquinimod in primary progressive multiple sclerosis.

Neurology 2020 08 10;95(8):e1027-e1040. Epub 2020 Jul 10.

From Barts and The London School of Medicine and Dentistry (G.G.), Blizard Institute, Queen Mary University of London, UK; Teva Pharmaceuticals R&D (V.K.), Teva Pharmaceutical Industries (T.L.), Great Valley, PA; Department of Neurology, Medical Faculty (V.K., H.-P.H.), Heinrich-Heine Universität Düsseldorf, Germany; Teva Pharmaceutical Industries (J.R.S., A.P.T.), Malvern, PA; Corinne Goldsmith Dickinson Center for Multiple Sclerosis (S.K.) and Neurology (F.L.), Icahn School of Medicine at Mount Sinai, New York, NY; Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Health and Center of Excellence for Biomedical Research (A.U.) and Department of Health Sciences (M.P.S.), University of Genoa; Ospedale Policlinico San Martino-IRCCS (A.U.), Genoa, Italy; Department of Neurology (B.M.J.U.), MS Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Division of Neurology (X.M.), University of Toronto/MS Centre St Michael's Hospital, Canada; Neurology-Neuroimmunology Department and Neurorehabilitation Unit (X.M.), Multiple Sclerosis Centre of Catalonia; Department of Neurology (X.M.), Hospital Universitari de la Vall d'Hebron, Barcelona, Spain; Weill Institute for Neurosciences (B.A.C.C.), Department of Neurology, University of California San Francisco; Radiology & Nuclear Medicine (F.L.), VU University Medical Center, Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000010284DOI Listing
August 2020

CD56bright Natural Killer Cells: A Possible Biomarker of Different Treatments in Multiple Sclerosis.

J Clin Med 2020 May 13;9(5). Epub 2020 May 13.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health and Center of Excellence for Biomedical Research, University of Genova, 16132 Genova, Italy.

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http://dx.doi.org/10.3390/jcm9051450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291063PMC
May 2020

COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role?

Mult Scler Relat Disord 2020 Jul 15;42:102120. Epub 2020 Apr 15.

Ospedale Policlinico San Martino, IRCCS, Genova, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) and Center of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2020.102120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156942PMC
July 2020

Fingolimod and Dimethyl-Fumarate-Derived Lymphopenia is not Associated with Short-Term Treatment Response and Risk of Infections in a Real-Life MS Population.

CNS Drugs 2020 04;34(4):425-432

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1007/s40263-020-00714-8DOI Listing
April 2020

Effects of aging on finger movements in multiple sclerosis.

Mult Scler Relat Disord 2020 Jan 14;37:101449. Epub 2019 Oct 14.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2019.101449DOI Listing
January 2020

Impact of treatment on cellular immunophenotype in MS: A cross-sectional study.

Neurol Neuroimmunol Neuroinflamm 2020 05 5;7(3). Epub 2020 Mar 5.

From the Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (M.C., F.I., M.P., A.L., C.L., G.N., G.B., E.S., S.P., M.I., N.K.d.R.) and Center of Excellence for Biomedical Research (A.U.), University of Genoa, Italy; BD Biosciences Italy (G.R.), Milan; Institut d'Investigacions Biomediques August Pi Sunyer (G.V., P.V.), Barcelona, Spain; Charité Universitaetsmedizin Berlin and Max Delbrueck Center for Molecular Medicine (P.B.-K., S.A., F.P.), Germany; Department of Research, Innovation and Education (T.B.), Neuroscience Research Unit, Oslo University Hospital; Department of Mechanical Electronics and Chemical Engineering (T.B.), Oslo Metropolitan University, Norway; University of Oslo (E.H., H.F.H.) and Oslo University Hospital (H.F.H.), Norway; Department of Mathematics and Padova Neuroscience Center (C.C.), University of Padua, Italy; Department of Mathematics (M.P.), University of Genoa, Italy; and IRCCS Ospedale Policlinico San Martino (A.L., M.P., M.I., A.U.), Genoa, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136062PMC
May 2020

Ghost spasticity in multiple sclerosis.

J Electromyogr Kinesiol 2020 Apr 20;51:102408. Epub 2020 Feb 20.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Italy; Department of Neuroscience, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jelekin.2020.102408DOI Listing
April 2020

Ocrelizumab does not impair B- and T-cell responses to primary VZV infection in a patient with MS.

Neurol Neuroimmunol Neuroinflamm 2020 05 25;7(3). Epub 2020 Feb 25.

From the Department of Neuroscience (G.N.), Ospedale Policlinico San Martino-IRCCS, Genoa; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) (F.I., E.S., N.K.d.R.), University of Genoa; Department of Health Sciences (DISSAL) (M.M.), University of Genoa; Ospedale Policlinico San Martino-IRCCS (M.M., G.P., M.I., A.U.), Genoa; Autoimmunity Laboratory Department of Internal Medicine (DiMI) (G.P.), University of Genoa; and Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) and Center of Excellence for Biomedical Research (CEBR) (M.I., A.U.), University of Genoa, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051194PMC
May 2020

Relationship between retinal inner nuclear layer, age, and disease activity in progressive MS.

Neurol Neuroimmunol Neuroinflamm 2019 09 12;6(5). Epub 2019 Aug 12.

From the Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI) (M.C., C.C., G. Boffa, G. Bommarito, E.S., G.N., C.L., A.U., M.I.), University of Genoa, Italy; Department of Neurology (C.C.), Multiple Sclerosis Center, University of California, San Francisco; Departments of Neurology, Radiology and Neuroscience (M.P., M.I.), Icahn School of Medicine at Mount Sinai, New York; and Ospedale Policlinico San Martino-IRCCS (E.C., A.U., M.I.), Genoa, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705649PMC
September 2019

Different MRI patterns in MS worsening after stopping fingolimod.

Neurol Neuroimmunol Neuroinflamm 2019 07 16;6(4):e566. Epub 2019 Apr 16.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics (C.L., M.C., G.B., M.P., G.N., G.L.M., A.U., M.I.), Maternal and Child Health (DiNOGMI), University of Genoa; Multiple Sclerosis Centre (D.B., A.G., M.Z.), Gallarate Hospital, ASST of Valle Olona, Gallarate; Department of Neurology (M.C., G.B., M.P., G.L.M., A.U.), Ospedale Policlinico San Martino-Sistema Sanitario Regione; Liguria -Istituto di Ricovero e Cura a Carattere Scientifico per l'Oncologia; IRCCS Foundation C. Mondino National Neurological Institute (I.C.), Pavia; Department of Health Sciences (DISSAL) (M.P.S., L. R.), Ospedale Policlinico San Martino IRCCS, Genoa, Italy; Department of Radiology and Neuroscience (M.I.), Icahn School of Medicine at Mount Sinai, New York; and Department of Neuroradiology (L.R.), Ospedale Policlinico San Martino IRCCS, Genoa, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481223PMC
July 2019

Fulminant Hepatitis Associated With Echovirus 25 During Treatment With Ocrelizumab for Multiple Sclerosis.

JAMA Neurol 2019 07;76(7):866-867

Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health and Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1001/jamaneurol.2019.0522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583842PMC
July 2019

CSF oligoclonal bands and normal appearing white matter periventricular damage in patients with clinically isolated syndrome suggestive of MS.

Mult Scler Relat Disord 2019 Jun 2;31:93-96. Epub 2019 Apr 2.

IRCCS Ospedale Policlinico, San Martino, Genova; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health and CEBR, University of Genoa, Genoa, Italy; Departments of Neurology, Radiology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.1016/j.msard.2019.03.027DOI Listing
June 2019

Ecological impact of isolated cognitive relapses in MS.

Mult Scler 2020 01 15;26(1):114-117. Epub 2018 Nov 15.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Health, University of Genoa, Genoa, Italy/IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

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http://dx.doi.org/10.1177/1352458518813722DOI Listing
January 2020

Neurological manifestations in autoinflammatory diseases.

Clin Exp Rheumatol 2018 Jan-Feb;36 Suppl 110(1):61-67. Epub 2018 May 3.

UO Pediatria 2, G. Gaslini Institute, Genoa, Italy.

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July 2018

Overexpression of sphingosine-1-phosphate receptors on reactive astrocytes drives neuropathology of multiple sclerosis rebound after fingolimod discontinuation.

Mult Scler 2018 07 30;24(8):1133-1137. Epub 2018 Apr 30.

Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1177/1352458518763095DOI Listing
July 2018

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: I: Fetal risks.

Neurology 2018 03 7;90(10):e823-e831. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (F.P.), University of Catania; Department of Neurology (C.S.), ASL3 Genovese; Multiple Sclerosis Center (P.B.), IRCCS Neuromed, Pozzilli; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005067DOI Listing
March 2018

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: II: Maternal risks.

Neurology 2018 03 7;90(10):e832-e839. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (C.S.), ASL3 Genovese; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005068DOI Listing
March 2018

Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration.

Metabolism 2017 12 8;77:39-46. Epub 2017 Sep 8.

Laboratorio di Immunologia, Istituto per l'Endocrinologia e l'Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Napoli, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Napoli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800394PMC
December 2017

Teriflunomide treatment reduces B cells in patients with MS.

Neurol Neuroimmunol Neuroinflamm 2017 Nov 23;4(6):e403. Epub 2017 Oct 23.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Unit (I.G., A.L., F.B., G.M., N.K.d.R., A.U.), and Center of Excellence for Biomedical Research (CEBR) (F.I., A.L., G.M., A.U.), University of Genoa, Italy; Ospedale Policlinico San Martino-IRCCS (A.L., G.M., A.U.), Genoa, Italy; and Rehabilitation Unit (C.S.), Centro di Recupero e Rieducazione Funzionale, M.L. Novarese, Moncrivello, Italy.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656406PMC
November 2017

A bridge between evidence-based laboratory diagnostics and research in neuroimmunology: why standardizations and guidelines matter.

Neurol Sci 2017 10;38(Suppl 2):213-216

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Unit, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1007/s10072-017-3022-6DOI Listing
October 2017

Dramatic rebounds of MS during pregnancy following fingolimod withdrawal.

Neurol Neuroimmunol Neuroinflamm 2017 Sep 27;4(5):e377. Epub 2017 Jul 27.

Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) (N.G., C.L., G.L.M., A.U.), University of Genoa, Italy; Multiple Sclerosis Study Center (A.G., P.A.), Hospital of Gallarate, Italy; San Paolo Hospital (M.P., F.B.), Savona, Italy; and IRCCS AUO San Martino-IST (G.L.M., A.U.), Genoa, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532747PMC
September 2017

Composite MRI measures and short-term disability in patients with clinically isolated syndrome suggestive of MS.

Mult Scler 2018 04 10;24(5):623-631. Epub 2017 Apr 10.

Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy/IRCCS AOU San Martino-IST, Genoa, Italy/Departments of Neurology, Radiology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1177/1352458517704077DOI Listing
April 2018

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis.

Front Immunol 2016 19;7:606. Epub 2016 Dec 19.

Centre of Excellence for Biomedical Research, University of Genova, Genova, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy; IRCCS San Martino-IST, Genova, Italy.

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http://dx.doi.org/10.3389/fimmu.2016.00606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165263PMC
December 2016

In vitro VLA-4 blockade results in an impaired NK cell-mediated immune surveillance against melanoma.

Immunol Lett 2017 01 2;181:109-115. Epub 2016 Dec 2.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Unit, University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Universitaria San Martino - IST, Genoa, Italy.

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http://dx.doi.org/10.1016/j.imlet.2016.11.015DOI Listing
January 2017

Safety and tolerability of fingolimod in patients with relapsing-remitting multiple sclerosis: results of an open-label clinical trial in Italy.

Neurol Sci 2017 Jan 18;38(1):53-59. Epub 2016 Oct 18.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Largo Daneo 3, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s10072-016-2701-zDOI Listing
January 2017

IFN-γ orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways.

J Allergy Clin Immunol 2017 May 23;139(5):1667-1676. Epub 2016 Sep 23.

Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Facoltà di Medicina e Chirurgia, Università di Genova, Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), Genoa, Italy; IRCCS AOU San Martino-IST, Genoa, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749163102
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http://dx.doi.org/10.1016/j.jaci.2016.09.004DOI Listing
May 2017

Dysregulation of regulatory CD56(bright) NK cells/T cells interactions in multiple sclerosis.

J Autoimmun 2016 08 4;72:8-18. Epub 2016 May 4.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Largo Daneo 3, 16132 Genova, Italy; Centre of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 9, 1612 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.04.003DOI Listing
August 2016

Human mesenchymal stem cells target adhesion molecules and receptors involved in T cell extravasation.

Stem Cell Res Ther 2015 Dec 10;6:245. Epub 2015 Dec 10.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132, Genova, Italy.

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http://dx.doi.org/10.1186/s13287-015-0222-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676115PMC
December 2015

Mesenchymal stromal cells and immunity: Introductory overview.

Immunol Lett 2015 Dec 2;168(2):127-8. Epub 2015 Sep 2.

IRCSS G. Gaslini, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2015.08.010DOI Listing
December 2015

Mesenchymal stem cells for the treatment of neurological diseases: Immunoregulation beyond neuroprotection.

Immunol Lett 2015 Dec 18;168(2):183-90. Epub 2015 Aug 18.

Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Largo Daneo 3, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 5, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2015.08.007DOI Listing
December 2015

The immunomodulatory function of mesenchymal stem cells: mode of action and pathways.

Ann N Y Acad Sci 2015 Sep 6;1351:114-26. Epub 2015 Jul 6.

Department of Neurology, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Health (DINOGMI).

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http://doi.wiley.com/10.1111/nyas.12815
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http://dx.doi.org/10.1111/nyas.12815DOI Listing
September 2015

Low intensity lympho-ablative regimen followed by autologous hematopoietic stem cell transplantation in severe forms of multiple sclerosis: A MRI-based clinical study.

Mult Scler 2015 Oct 12;21(11):1423-30. Epub 2015 Jan 12.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health; University of Genova; Italy/Department of Health Sciences, University of Genova, Italy

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http://dx.doi.org/10.1177/1352458514564484DOI Listing
October 2015

Selective impairments of motor sequence learning in multiple sclerosis patients with minimal disability.

Brain Res 2014 Oct 20;1585:91-8. Epub 2014 Aug 20.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2014.08.031DOI Listing
October 2014

Cingulum bundle alterations underlie subjective fatigue in multiple sclerosis.

Mult Scler 2015 Apr 21;21(4):442-7. Epub 2014 Aug 21.

Magnetic Resonance Research Centre on Nervous System Diseases, University of Genoa/San Martino University Hospital/ University of Genoa, Genoa, Italy

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http://dx.doi.org/10.1177/1352458514546791DOI Listing
April 2015

Safety of the first dose of fingolimod for multiple sclerosis: results of an open-label clinical trial.

BMC Neurol 2014 Apr 1;14:65. Epub 2014 Apr 1.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Largo Daneo 3, 16132 Genoa, Italy.

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http://dx.doi.org/10.1186/1471-2377-14-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005629PMC
April 2014

Isolated cognitive relapses in multiple sclerosis.

J Neurol Neurosurg Psychiatry 2014 Sep 31;85(9):1035-7. Epub 2014 Mar 31.

Magnetic Resonance Research Centre on Nervous System Diseases, University of Genoa, Genoa, Italy Department of Diagnostic and Interventional Neuroradiology, San Martino University Hospital, Genoa, Italy Department of Health Sciences, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1136/jnnp-2013-307275DOI Listing
September 2014

Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis.

Immunology 2014 Mar;141(3):328-39

Department of Neurosciences, Ophthalmology, Genetics, Rehabilitation and Child Health, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/imm.12177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930371PMC
March 2014

CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.

Neuropharmacology 2013 Dec 16;75:337-46. Epub 2013 Aug 16.

Department of Pharmacy, Section of Pharmacology and Toxicology, University of Genoa, Viale Cembrano 4, Genoa 16148, Italy; Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, Genoa 16132, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2013.07.037DOI Listing
December 2013

Quantitative assessment of finger motor impairment in multiple sclerosis.

PLoS One 2013 31;8(5):e65225. Epub 2013 May 31.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065225PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669283PMC
January 2014

Fingolimod modulates peripheral effector and regulatory T cells in MS patients.

J Neuroimmune Pharmacol 2013 Dec 7;8(5):1106-13. Epub 2013 May 7.

Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s11481-013-9465-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889247PMC
December 2013

Towards clinical application of mesenchymal stem cells for treatment of neurological diseases of the central nervous system.

J Neuroimmune Pharmacol 2013 Dec 12;8(5):1062-76. Epub 2013 Apr 12.

Department of Neurosciences Ophthalmology, Genetics, Rehabilitation and Child Health, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1007/s11481-013-9456-6DOI Listing
December 2013

Mesenchymal stem cells as treatment for MS - progress to date.

Mult Scler 2013 Apr 1;19(5):515-9. Epub 2012 Nov 1.

Department of Neurosciences Ophthalmology and Genetics, University of Genoa, Italy.

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http://dx.doi.org/10.1177/1352458512464686DOI Listing
April 2013

Mesenchymal stem cells shape microglia effector functions through the release of CX3CL1.

Stem Cells 2012 Sep;30(9):2044-53

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1002/stem.1174DOI Listing
September 2012

T-cell trafficking in the central nervous system.

Immunol Rev 2012 Jul;248(1):216-27

Institute for Research in Biomedicine, Bellinzona, Switzerland.

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http://dx.doi.org/10.1111/j.1600-065X.2012.01140.xDOI Listing
July 2012

Reward responsiveness and fatigue in multiple sclerosis.

Mult Scler 2013 Feb 21;19(2):233-40. Epub 2012 Jun 21.

University of Genoa, Italy.

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http://dx.doi.org/10.1177/1352458512451509DOI Listing
February 2013

Neurorepair with mesenchymal stem cells: hope or hype?

Lancet Neurol 2012 Feb 10;11(2):123-5. Epub 2012 Jan 10.

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http://dx.doi.org/10.1016/S1474-4422(12)70001-7DOI Listing
February 2012

Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells.

Proc Natl Acad Sci U S A 2011 Oct 29;108(42):17384-9. Epub 2011 Sep 29.

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, 16132 Genoa, Italy.

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http://dx.doi.org/10.1073/pnas.1103650108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198360PMC
October 2011

Can we kill an extra bird with the same stone?

Inflamm Bowel Dis 2011 Sep 24;17(9):E124-5. Epub 2011 Jun 24.

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http://dx.doi.org/10.1002/ibd.21802DOI Listing
September 2011

Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases.

Lancet Neurol 2011 Jul;10(7):649-56

Department of Neurosciences, Ophthalmology, and Genetics, University of Genoa, Italy.

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http://dx.doi.org/10.1016/S1474-4422(11)70121-1DOI Listing
July 2011

Primary varicella zoster infection associated with fingolimod treatment.

Neurology 2011 Mar;76(11):1023-4

Department of Neuroscience, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132, Genoa, Italy.

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http://dx.doi.org/10.1212/WNL.0b013e31821043b5DOI Listing
March 2011

Neuroprotective features of mesenchymal stem cells.

Best Pract Res Clin Haematol 2011 Mar 25;24(1):59-64. Epub 2011 Feb 25.

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.beha.2011.01.004DOI Listing
March 2011

Systemic administration of mesenchymal stem cells increases neuron survival after global cerebral ischemia in vivo (2VO).

Neural Plast 2010 19;2010:534925. Epub 2010 Dec 19.

Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Via De Toni 5, 16132 Genova, Italy.

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http://dx.doi.org/10.1155/2010/534925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039275PMC
January 2012

Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?

Curr Opin Immunol 2010 Dec 17;22(6):768-74. Epub 2010 Nov 17.

Department of Neurosciences Ophthalmology and Genetics, University of Genoa, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S095279151000162
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http://dx.doi.org/10.1016/j.coi.2010.10.012DOI Listing
December 2010

Mesenchymal stem cells for multiple sclerosis: does neural differentiation really matter?

Curr Stem Cell Res Ther 2011 Mar;6(1):69-72

Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy.

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http://dx.doi.org/10.2174/157488811794480744DOI Listing
March 2011

Alterations of glutamate release in the spinal cord of mice with experimental autoimmune encephalomyelitis.

J Neurochem 2010 Oct 25;115(2):343-52. Epub 2010 Aug 25.

Department of Experimental Medicine, University of Genoa, Genoa, Italy.

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http://doi.wiley.com/10.1111/j.1471-4159.2010.06923.x
Publisher Site
http://dx.doi.org/10.1111/j.1471-4159.2010.06923.xDOI Listing
October 2010

Stem cell transplantation in multiple sclerosis.

Curr Opin Neurol 2010 Jun;23(3):218-25

Department of Neurosciences, Ophthalmology and Genetics, Italy.

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http://dx.doi.org/10.1097/WCO.0b013e328338b7edDOI Listing
June 2010

Immuno-therapeutic potential of haematopoietic and mesenchymal stem cell transplantation in MS.

Results Probl Cell Differ 2010 ;51:237-57

Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College Building 560/Burlington Danes, Room E415, Imperial College London, 160 Du Cane Road, London, UK.

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http://dx.doi.org/10.1007/400_2008_14DOI Listing
November 2010