Publications by authors named "Antonio Daga"

68Publications

Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells.

Cancers (Basel) 2019 Jun 24;11(6). Epub 2019 Jun 24.

Laboratory of Tumor Epigenetics, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.

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http://dx.doi.org/10.3390/cancers11060878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627323PMC
June 2019

The efficacy and toxicity of ATM inhibition in glioblastoma initiating cells-driven tumor models.

Crit Rev Oncol Hematol 2019 Jun 21;138:214-222. Epub 2019 Apr 21.

Regenerative Medicine, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2019.04.015DOI Listing
June 2019

Radiosensitization of orthotopic GIC-driven glioblastoma by doxycycline causes skin damage.

Radiat Oncol 2019 Apr 8;14(1):58. Epub 2019 Apr 8.

Cell Oncology, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy.

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http://dx.doi.org/10.1186/s13014-019-1266-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454723PMC
April 2019

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma.

Int J Cancer 2019 06 9;144(12):3146-3159. Epub 2019 Jan 9.

Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/ijc.32058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491995PMC
June 2019

An RGD small-molecule integrin antagonist induces detachment-mediated anoikis in glioma cancer stem cells.

Int J Oncol 2018 Dec 3;53(6):2683-2694. Epub 2018 Oct 3.

Department of Drug Sciences, University of Pavia, I-27100 Pavia, Italy.

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http://dx.doi.org/10.3892/ijo.2018.4583DOI Listing
December 2018

Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation.

Drug Deliv Transl Res 2018 10;8(5):1345-1354

Department of Health Sciences, University of Genoa, via A. Pastore, 1, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s13346-018-0535-3DOI Listing
October 2018

In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity.

Exp Cell Res 2018 02 4;363(1):48-64. Epub 2018 Jan 4.

Section of Pharmacology, Department of Internal Medicine, and Center of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.01.002DOI Listing
February 2018

Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors.

Front Cell Neurosci 2017 13;11:312. Epub 2017 Oct 13.

Section of Pharmacology, Department of Internal Medicine and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.

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http://dx.doi.org/10.3389/fncel.2017.00312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645520PMC
October 2017

Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.

Sci Rep 2017 10 25;7(1):14049. Epub 2017 Oct 25.

Dipartimento di terapie oncologiche integrate, IRCCS A.O.U. San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Largo R. Benzi 10, 16132, Genova, Italy.

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http://dx.doi.org/10.1038/s41598-017-14417-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656588PMC
October 2017

Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas.

Mol Neurobiol 2017 09 11;54(7):4879-4895. Epub 2016 Aug 11.

Pharmacology Section, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s12035-016-0025-xDOI Listing
September 2017

Carnosic acid induces proteasomal degradation of Cyclin B1, RB and SOX2 along with cell growth arrest and apoptosis in GBM cells.

Phytomedicine 2016 Jun 6;23(7):679-85. Epub 2016 Apr 6.

IRCCS AOU - San Martino - IST, Largo Rosanna Benzi, 10, 16132 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2016.03.007DOI Listing
June 2016

Emx2 as a novel tool to suppress glioblastoma.

Oncotarget 2016 Jul;7(27):41005-41016

Department of Neuroscience, SISSA, 34136 Trieste, Italy.

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http://dx.doi.org/10.18632/oncotarget.9322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173038PMC
July 2016

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells.

Oncotarget 2016 Mar;7(12):14366-79

Department of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", 28100 Novara, Italy.

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http://dx.doi.org/10.18632/oncotarget.7321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924721PMC
March 2016

Anti-Tumor Effects of Bak-Proteoliposomes against Glioblastoma.

Molecules 2015 Sep 1;20(9):15893-909. Epub 2015 Sep 1.

The Rex Laboratory, TIMC IMAG, UMR5525, UJF/CNRS, Joseph Fourier University, CHU-Grenoble, BP217, Grenoble Cedex 9 38043, France.

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http://www.mdpi.com/1420-3049/20/9/15893
Publisher Site
http://dx.doi.org/10.3390/molecules200915893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332045PMC
September 2015

Molecular Pharmacology of Malignant Pleural Mesothelioma: Challenges and Perspectives From Preclinical and Clinical Studies.

Curr Drug Targets 2016 ;17(7):824-49

Section of Pharmacology, Department of. Internal Medicine (Di.M.I.), University of Genova, Viale Benedetto XV, 2 16132 Genova, Italy.

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http://dx.doi.org/10.2174/1389450116666150804110714DOI Listing
December 2016

Agonist activation of estrogen receptor beta (ERβ) sensitizes malignant pleural mesothelioma cells to cisplatin cytotoxicity.

Mol Cancer 2014 Oct 2;13:227. Epub 2014 Oct 2.

Department of Pharmaceutical Sciences, University of Piemonte Orientale "A, Avogadro", Lgo Donegani 2, 28100 Novara, Italy.

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http://dx.doi.org/10.1186/1476-4598-13-227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197308PMC
October 2014

Predictability, efficacy and safety of radiosensitization of glioblastoma-initiating cells by the ATM inhibitor KU-60019.

Int J Cancer 2014 Jul 8;135(2):479-91. Epub 2014 Jan 8.

Mutagenesis Unit, IRCCS Azienda Ospedaliera Universitaria San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.1002/ijc.28680DOI Listing
July 2014

Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity.

Toxicology 2013 Dec 21;314(2-3):209-20. Epub 2013 Oct 21.

Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.tox.2013.10.003DOI Listing
December 2013

Amniotic fluid stem cells in a bone microenvironment: driving host angiogenic response.

Stem Cell Res 2013 Jul 24;11(1):540-51. Epub 2013 Feb 24.

Department of Experimental Medicine (DIMES), University of Genova, 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.scr.2013.02.006DOI Listing
July 2013

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.

Cell Cycle 2013 Feb 16;12(3):491-500. Epub 2013 Jan 16.

Department of Experimental Medicine (DIMES), University of Genova, Genova, Italy.

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http://dx.doi.org/10.4161/cc.23372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587450PMC
February 2013

Antagonistic modulation of gliomagenesis by Pax6 and Olig2 in PDGF-induced oligodendroglioma.

Int J Cancer 2012 Oct 17;131(7):E1078-87. Epub 2012 May 17.

Department of Experimental Medicine, DIMES, University of Genoa, Genoa 16132, Italy.

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http://dx.doi.org/10.1002/ijc.27606DOI Listing
October 2012

Isolation of stem-like cells from spontaneous feline mammary carcinomas: phenotypic characterization and tumorigenic potential.

Exp Cell Res 2012 Apr 16;318(7):847-60. Epub 2012 Feb 16.

Section of Pharmacology, Dept. of Internal Medicine Di.M.I., and Center of Excellence for Biomedical Research - University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S001448271200064
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http://dx.doi.org/10.1016/j.yexcr.2012.02.008DOI Listing
April 2012

New perspectives in glioma immunotherapy.

Curr Pharm Des 2011 ;17(23):2439-67

Department of Translational Oncology, National Institute for Cancer Research, 16132 Genova, Italy.

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http://dx.doi.org/10.2174/138161211797249206DOI Listing
May 2012

In vitro and in vivo characterization of highly purified human mesothelioma derived cells.

BMC Cancer 2010 Feb 22;10:54. Epub 2010 Feb 22.

Department of Oncology, Biology and Genetics, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1186/1471-2407-10-54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850899PMC
February 2010

Comparative analysis of DNA repair in stem and nonstem glioma cell cultures.

Mol Cancer Res 2009 Mar 10;7(3):383-92. Epub 2009 Mar 10.

Molecular Mutagenesis and DNA Repair Laboratory, Istituto Nazionale Ricerca Cancro, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0409DOI Listing
March 2009

MR and iron magnetic nanoparticles. Imaging opportunities in preclinical and translational research.

Tumori 2008 Mar-Apr;94(2):226-33

Department of Diagnostic Imaging, Istituto Nazionale per la Ricerca sul Cancro, IST, Genoa, Italy.

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July 2008

Ligand-targeted liposomal therapies of neuroblastoma.

Curr Med Chem 2007 ;14(29):3070-8

Differentiation Therapy Unit, Laboratory of Oncology, G. Gaslini Children's Hospital, Genoa, Italy.

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http://dx.doi.org/10.2174/092986707782793916DOI Listing
March 2008

Glioma immunotherapy by IL-21 gene-modified cells or by recombinant IL-21 involves antibody responses.

Int J Cancer 2007 Oct;121(8):1756-63

Department of Translational Oncology, IST-National Institute for Cancer Research, Genova, Italy.

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http://dx.doi.org/10.1002/ijc.22901DOI Listing
October 2007

DNase I behaves as a transcription factor which modulates Fas expression in human cells.

Eur J Immunol 2004 Jan;34(1):273-9

Department of Experimental Medicine, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1002/eji.200223817DOI Listing
January 2004