Publications by authors named "Antje Sucker"

90Publications

Clinical and genetic analysis of melanomas arising in acral sites.

Eur J Cancer 2019 09 14;119:66-76. Epub 2019 Aug 14.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany; Dermatological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.008DOI Listing
September 2019

Impact of American Joint Committee on Cancer 8th edition classification on staging and survival of patients with melanoma.

Eur J Cancer 2019 09 8;119:18-29. Epub 2019 Aug 8.

Department of Dermatology, University Hospital Essen, Essen, Germany and German Cancer Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.06.011DOI Listing
September 2019

Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters.

Eur J Cardiothorac Surg 2019 Dec;56(6):1104-1109

Department of Thoracic Surgery, University Medicine Essen-Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1093/ejcts/ezz211DOI Listing
December 2019

Tumor CDKN2A-Associated JAK2 Loss and Susceptibility to Immunotherapy Resistance.

J Natl Cancer Inst 2018 06;110(6):677-681

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, and German Cancer Consortium partner site Essen/Düsseldorf, Essen, Germany (DKTK).

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http://dx.doi.org/10.1093/jnci/djx271DOI Listing
June 2018

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling.

Clin Cancer Res 2018 09 11;24(18):4494-4504. Epub 2018 Jun 11.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0763DOI Listing
September 2018

Role of Elevated Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma.

Clin Cancer Res 2018 09 18;24(17):4119-4125. Epub 2018 May 18.

Center for Melanoma Research and Treatment, California Pacific Medical Center (CPMC) Research Institute, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125189PMC
September 2018

STAT5 expression correlates with recurrence and survival in melanoma patients treated with interferon-α.

Melanoma Res 2018 06;28(3):204-210

Department of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg.

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http://Insights.ovid.com/crossref?an=00008390-900000000-9931
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http://dx.doi.org/10.1097/CMR.0000000000000435DOI Listing
June 2018

Liquid Profiling of Circulating Tumor DNA in Plasma of Melanoma Patients for Companion Diagnostics and Monitoring of BRAF Inhibitor Therapy.

Clin Chem 2018 05 26;64(5):830-842. Epub 2018 Feb 26.

Department of Clinical Chemistry, University Medical Centre, Ruprecht-Karls University of Heidelberg, Mannheim, Germany;

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http://dx.doi.org/10.1373/clinchem.2017.281543DOI Listing
May 2018

Intraventricular melanocytoma diagnosis confirmed by gene mutation profile.

Neuropathology 2018 Jun 11;38(3):288-292. Epub 2017 Dec 11.

Institute of Pathology, Ruhr University Bochum, Bochum, Germany.

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http://dx.doi.org/10.1111/neup.12443DOI Listing
June 2018

PD-L1 status does not predict the outcome of BRAF inhibitor therapy in metastatic melanoma.

Eur J Cancer 2018 01 28;88:67-76. Epub 2017 Nov 28.

Skin Cancer Center Hannover, Dept. of Dermatology and Allergy, Hannover Medical School, Carl Neuberg Str. 1, 30625 Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.10.026DOI Listing
January 2018

Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma.

Invest Ophthalmol Vis Sci 2017 07;58(9):3464-3470

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany 8Dermatopathologie bei Mainz, Nieder-Olm, Germany.

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http://dx.doi.org/10.1167/iovs.17-21838DOI Listing
July 2017

Activating CYSLTR2 and PLCB4 Mutations in Primary Leptomeningeal Melanocytic Tumors.

J Invest Dermatol 2017 09 10;137(9):2033-2035. Epub 2017 May 10.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany; Dermatopathologie bei Mainz, Nieder-Olm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572104PMC
September 2017

Targeted next generation sequencing of mucosal melanomas identifies frequent NF1 and RAS mutations.

Oncotarget 2017 Jun;8(25):40683-40692

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), University of Duisburg-Essen, Duisburg/Essen, Germany.

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http://dx.doi.org/10.18632/oncotarget.16542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522195PMC
June 2017

IRF4 rs12203592 functional variant and melanoma survival.

Int J Cancer 2017 04 6;140(8):1845-1849. Epub 2017 Feb 6.

Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.30605DOI Listing
April 2017

Oncogene Status of an Interdigitating Dendritic Cell Sarcoma: Recurrent Mutations in NF1, TP53, and ARID2 Shared With Melanoma.

Am J Surg Pathol 2016 12;40(12):1721-1723

*Department of Dermatology Venerology and Allergology, University Hospital, University of Duisburg-Essen †German Cancer Consortium (DKTK) ‡Zentrum für Pathologie Essen-Mitte Essen, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000746DOI Listing
December 2016

Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA.

Oncotarget 2016 Sep;7(37):59115-59128

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.18632/oncotarget.10827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312299PMC
September 2016

Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency.

Cancer Res 2016 08 3;76(15):4347-58. Epub 2016 Jun 3.

Department of Dermatology, University Hospital Essen, University Duisburg-Essen and German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0008DOI Listing
August 2016

Inherited functional variants of the lymphocyte receptor CD5 influence melanoma survival.

Int J Cancer 2016 09 31;139(6):1297-302. Epub 2016 May 31.

Grup D'Immunoreceptors Del Sistema Innat I Adaptatiu, Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.30184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503133PMC
September 2016

Diagnosing a Primary Leptomeningeal Melanoma by Gene Mutation Signature.

J Invest Dermatol 2016 07 7;136(7):1526-1528. Epub 2016 Apr 7.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533509PMC
July 2016

Oncogene status as a diagnostic tool in ocular and cutaneous melanoma.

Eur J Cancer 2016 Apr 23;57:112-7. Epub 2016 Feb 23.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.01.010DOI Listing
April 2016

Phenotypic characterization and prognostic impact of circulating γδ and αβ T-cells in metastatic malignant melanoma.

Int J Cancer 2016 Feb 18;138(3):698-704. Epub 2015 Sep 18.

Department of Internal Medicine II, University Medical Center, Tübingen, Germany.

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http://doi.wiley.com/10.1002/ijc.29818
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http://dx.doi.org/10.1002/ijc.29818DOI Listing
February 2016

Frequent TERT Promoter Mutations in Ocular Surface Squamous Neoplasia.

Invest Ophthalmol Vis Sci 2015 Sep;56(10):5854-61

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany.

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http://dx.doi.org/10.1167/iovs.15-17469DOI Listing
September 2015

Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab.

Clin Cancer Res 2015 Dec 19;21(24):5453-9. Epub 2015 Aug 19.

Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg and Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0676DOI Listing
December 2015

Deciphering the genetic evolution of T-cell resistance in melanoma.

Oncoimmunology 2015 May 3;4(5):e1005510. Epub 2015 Feb 3.

Department of Dermatology; University Hospital; University Duisburg-Essen and German Cancer Consortium (DKTK) ; Essen, Germany.

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http://dx.doi.org/10.1080/2162402X.2015.1005510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485751PMC
May 2015

STAT3 Single Nucleotide Polymorphism rs4796793 SNP Does Not Correlate with Response to Adjuvant IFNα Therapy in Stage III Melanoma Patients.

Front Med (Lausanne) 2014 28;1:47. Epub 2014 Nov 28.

Department of Dermatology, University Hospital Essen , Essen , Germany ; Department of Dermatology, Medical University of Graz , Graz , Austria ; Department of Translational Skin Cancer Research, German Cancer Research Center , Heidelberg , Germany.

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http://dx.doi.org/10.3389/fmed.2014.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292185PMC
January 2015

Genetic evolution of T-cell resistance in the course of melanoma progression.

Clin Cancer Res 2014 Dec 7;20(24):6593-604. Epub 2014 Oct 7.

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany. German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0567DOI Listing
December 2014

TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.

J Natl Cancer Inst 2014 Sep 13;106(9). Epub 2014 Sep 13.

Department of Dermatology,University Hospital Essen, West German Cancer Center, University Duisburg-Essen, Essen and the German Cancer Consortium (KGG, BS, EL, TS, IM, MS, AS, UH, LZ, DS), Germany; Department of Pathology and Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY (RM); CIBER Enfermedades Raras, Instituto de Salud Carlos III, Barcelona, Spain (JAPB, MP, CC, CB, JM, SP); Department of Dermatology, Hospital Clinic Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, Spain (CC, JM, SP); Biochemistry and Molecular Genetics Department, Hospital Clinic Barcelona, IDIBAPS, Barcelona, Spain (CB); Integriertes Forschungs- und Behandlungszentrum (IFB) Sepsis und Sepsisfolgen Center for Sepsis Control and Care (CSCC) University Hospital Jena, Jena, Germany (AS).

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http://dx.doi.org/10.1093/jnci/dju246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200061PMC
September 2014

Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells.

Clin Cancer Res 2014 Mar 9;20(6):1601-9. Epub 2013 Dec 9.

Authors' Affiliations: Department of Dermatology, University Medical Center; Department of Internal Medicine II, Section for Transplantation Immunology and Immunohematology, University of Tübingen, Tübingen; German Cancer Research Center (DKFZ); German Cancer Consortium (DKTK), Heidelberg; Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen, Essen, Germany; Department of Medical Oncology and Immunotherapy, University Hospital of Siena, Istituto Toscano Tumori, Italy; and Skin Cancer Research Group, School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2508DOI Listing
March 2014

The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.

Cancer Discov 2014 Jan 21;4(1):94-109. Epub 2013 Nov 21.

1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; 2Department of Pathology, Massachusetts General Hospital Cancer Center, Boston; 3Broad Institute of MIT and Harvard; 4Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts; 5Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen, Essen; 6German Cancer Consortium (DKTK); 7Department of Dermatology, Heidelberg University Hospital, Heidelberg; 8Department of Dermatology and Allergy, Hannover Medical School, Hannover; 9Department of Dermatology, University of Wuerzburg, Wuerzburg; 10Department of Dermatology, Venerology and Allergology, University of Schleswig-Holstein Hospital, Kiel; 11Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich; 12Department of Dermatology, Venerology and Allergy, Charité Universitätsmedizin Berlin, Humboldt University, Berlin; 13Department of Dermatology, University of Mainz, Mainz; 14University Medical Center, University of Tübingen, Tübingen, Germany; 15Department of Genome Sciences, University of Washington, Seattle, Washington; 16Department of Dermatology, University Hospital Zurich, Zurich, Switzerland; and 17First Department of Medicine, Medical School, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947264PMC
January 2014

Conjunctival melanomas harbor BRAF and NRAS mutations--response.

Clin Cancer Res 2013 Nov 29;19(22):6331-2. Epub 2013 Oct 29.

Authors' Affiliations: Departments of Dermatology and Ophthalmology, University Hospital, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2368DOI Listing
November 2013

Genetic and clinico-pathologic analysis of metastatic uveal melanoma.

Mod Pathol 2014 Feb 26;27(2):175-83. Epub 2013 Jul 26.

1] Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA [2] Department of Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/modpathol.2013.138DOI Listing
February 2014

Lack of SF3B1 R625 mutations in cutaneous melanoma.

Diagn Pathol 2013 May 21;8:87. Epub 2013 May 21.

Department of Dermatology, University Hospital, University Duisburg-Essen, Hufelandstrasse 55, Essen 45147, Germany.

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http://link.springer.com/content/pdf/10.1186%2F1746-1596-8-8
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http://diagnosticpathology.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/1746-1596-8-87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671181PMC
May 2013

Vemurafenib reverses immunosuppression by myeloid derived suppressor cells.

Int J Cancer 2013 Oct 13;133(7):1653-63. Epub 2013 Apr 13.

Department of Dermatology, University Hospital, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/ijc.28168DOI Listing
October 2013

TERT promoter mutations in familial and sporadic melanoma.

Science 2013 Feb 24;339(6122):959-61. Epub 2013 Jan 24.

Division of Molecular Genetic Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1126/science.1230062DOI Listing
February 2013

Integrin genes and susceptibility to human melanoma.

Mutagenesis 2012 May 20;27(3):367-73. Epub 2011 Dec 20.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1093/mutage/ger090DOI Listing
May 2012

Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.

Genes Chromosomes Cancer 2010 Aug;49(8):733-45

Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.20785DOI Listing
August 2010

A multimarker prognostic assay for primary cutaneous melanoma.

Clin Cancer Res 2009 Nov 3;15(22):6987-92. Epub 2009 Nov 3.

Auerback Melanoma Research Laboratory and Melanoma Center, Comprehensive Cancer Center, and Departments of Pathology, Surgery, and Urology, University of California-San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784204PMC
November 2009

Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B.

Clin Cancer Res 2009 Aug 11;15(16):5208-15. Epub 2009 Aug 11.

Clinical Cooperation Unit Dermato-Oncology, German Cancer Research Center Heidelberg and University Medicine Mannheim, University Medicine Mannheim, Mannheim, Germany.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-09-0886DOI Listing
August 2009

Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma.

Clin Cancer Res 2009 Feb;15(4):1384-92

Joint Research Division of Vascular Biology, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.

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http://clincancerres.aacrjournals.org/content/15/4/1384.full
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-1615DOI Listing
February 2009

Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma.

Int J Cancer 2005 Dec;117(5):825-30

Skin Cancer Unit, German Cancer Research Center Heidelberg/Department of Dermatology, University Hospital Mannheim, Germany.

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http://dx.doi.org/10.1002/ijc.21073DOI Listing
December 2005

Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events.

Int J Cancer 2003 Mar;103(6):759-67

Skin Cancer Unit, German Cancer Research Center, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1002/ijc.10906DOI Listing
March 2003

Collection of autologous monocytes for dendritic cell vaccination therapy in metastatic melanoma patients.

Transfusion 2002 Apr;42(4):428-32

Institute of Transfusion Medicine and Immunology, Red Cross Blood Service of Baden-Württemberg, Faculty of Clinical Medicine Mannheim, Germany.

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http://dx.doi.org/10.1046/j.1525-1438.2002.00067.xDOI Listing
April 2002