Publications by authors named "Anna Zachariou"

26Publications

Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability.

Am J Hum Genet 2017 May;100(5):725-736

Division of Genetics and Epidemiology, Institute of Cancer Research, 15 Cotswold Road, London SM2 5NG, UK; Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK. Electronic address:

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May 2017

Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour.

Nat Commun 2014 Aug 7;5:4398. Epub 2014 Aug 7.

1] Division of Genetics and Epidemiology, Institute of Cancer Research, London SM2 5NG, UK [2] Cancer Genetics Unit, Royal Marsden Hospital NHS Foundation Trust, London SM2 5PT, UK.

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August 2014

IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.

Nat Cell Biol 2005 Jan 5;7(1):70-7. Epub 2004 Dec 5.

The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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January 2005

IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding.

EMBO J 2003 Dec;22(24):6642-52

The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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December 2003

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

Nat Cell Biol 2003 May;5(5):467-73

The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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May 2003

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1.

EMBO J 2002 Oct;21(19):5118-29

The Breakthrough Toby Robins Breast Cancer Research, Institute of Cancer Research, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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October 2002

The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis.

Nat Cell Biol 2002 Jun;4(6):445-50

The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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June 2002