Anna J Ucher

Anna J Ucher

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Anna J Ucher

Anna J Ucher

Publications by authors named "Anna J Ucher"

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Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.

PLoS One 2015 12;10(8):e0134397. Epub 2015 Aug 12.

Department of Microbiology and Physiological Systems, Univ. of Massachusetts Medical School, Worcester, MA, 01605, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134397PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534307PMC
May 2016

Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.

Proc Natl Acad Sci U S A 2014 Jun 9;111(25):9217-22. Epub 2014 Jun 9.

Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and

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http://dx.doi.org/10.1073/pnas.1405590111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078814PMC
June 2014

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

J Immunol 2014 May 11;192(10):4887-96. Epub 2014 Apr 11.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605.

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http://dx.doi.org/10.4049/jimmunol.1303481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049217PMC
May 2014

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.

DNA Repair (Amst) 2013 Dec 29;12(12):1087-93. Epub 2013 Sep 29.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, United States.

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http://dx.doi.org/10.1016/j.dnarep.2013.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000569PMC
December 2013

The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.

PLoS One 2012 20;7(4):e36061. Epub 2012 Apr 20.

Department of Microbiology and Physiological Systems, Medical School, University of Massachusetts, Worcester, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334981PMC
August 2012

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

J Immunol 2011 Sep 29;187(5):2464-75. Epub 2011 Jul 29.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.4049/jimmunol.1101406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159830PMC
September 2011

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells.

Mol Cell 2011 Jan;41(2):232-42

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655-0122, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109727651100008
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http://dx.doi.org/10.1016/j.molcel.2011.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044441PMC
January 2011