Anna C Need

Anna C Need

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Anna C Need

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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 Aug;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
August 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Cell Rep 2017 Nov;21(9):2597-2613

Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789458PMC
November 2017

The importance of dynamic re-analysis in diagnostic whole exome sequencing.

J Med Genet 2017 03 29;54(3):155-156. Epub 2016 Nov 29.

Institute for Genomic Medicine, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1136/jmedgenet-2016-104306DOI Listing
March 2017

Neuropsychiatric genomics in precision medicine: diagnostics, gene discovery, and translation.

Dialogues Clin Neurosci 2016 09;18(3):237-252

Institute for Genomic Medicine, Columbia University, New York, NY, 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067142PMC
September 2016

Where now for schizophrenia research?

Eur Neuropsychopharmacol 2014 Aug 28;24(8):1181-7. Epub 2014 May 28.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2014.05.012DOI Listing
August 2014

Schizophrenia genetics comes of age.

Neuron 2014 Aug;83(4):760-3

Center for Human Genome Variation, Duke University Medical School, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.08.015DOI Listing
August 2014

One gene, many neuropsychiatric disorders: lessons from Mendelian diseases.

Nat Neurosci 2014 Jun 27;17(6):773-81. Epub 2014 May 27.

Center for Human Genome Variation, Duke University School of Medicine, Durham, North Carolina, USA.

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http://psych.colorado.edu/~carey/pdffiles/mendelianpsychiatr
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http://www.nature.com/doifinder/10.1038/nn.3713
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http://dx.doi.org/10.1038/nn.3713DOI Listing
June 2014

A comparison of the Cambridge Automated Neuropsychological Test Battery (CANTAB) with "traditional" neuropsychological testing instruments.

J Clin Exp Neuropsychol 2013 27;35(3):319-28. Epub 2013 Feb 27.

Division of Medical Psychology, Duke University School of Medicine, Durham, NC 27710, USA.

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http://www.tandfonline.com/doi/abs/10.1080/13803395.2013.771
Publisher Site
http://dx.doi.org/10.1080/13803395.2013.771618DOI Listing
August 2013

Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks.

Hippocampus 2011 Sep 20;21(9):980-9. Epub 2010 May 20.

Department of Psychology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1002/hipo.20809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010486PMC
September 2011

SVA: software for annotating and visualizing sequenced human genomes.

Bioinformatics 2011 Jul 29;27(14):1998-2000. Epub 2011 May 29.

Center for Human Genome Variation, Duke University School of Medicine, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129530PMC
July 2011

Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

J Alzheimers Dis 2010 ;19(1):69-77

Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University Medical Center, Durham, NC 27708, USA.

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http://dx.doi.org/10.3233/JAD-2010-1212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883723PMC
August 2010

Common genetic variation and performance on standardized cognitive tests.

Eur J Hum Genet 2010 Jul 3;18(7):815-20. Epub 2010 Feb 3.

Center for Human Genome Variation, Duke Institute for Genome Sciences & Policy, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1038/ejhg.2010.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987367PMC
July 2010

Whole genome association studies in complex diseases: where do we stand?

Dialogues Clin Neurosci 2010 ;12(1):37-46

Institute for Genome Sciences and Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina 27708, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181943PMC
April 2010

Next generation disparities in human genomics: concerns and remedies.

Trends Genet 2009 Nov;25(11):489-94

Institute for Genome Sciences and Policy, Center for Human Genome Variation, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.tig.2009.09.012DOI Listing
November 2009

Common variants conferring risk of schizophrenia.

Nature 2009 Aug 1;460(7256):744-7. Epub 2009 Jul 1.

deCODE genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/nature08186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077530PMC
August 2009

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

Eur J Hum Genet 2009 Jul 21;17(7):946-57. Epub 2009 Jan 21.

Center for Human Genome Variation, Institute for Genome Sciences & Policy, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1038/ejhg.2008.264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986499PMC
July 2009

Large recurrent microdeletions associated with schizophrenia.

Nature 2008 Sep;455(7210):232-6

CNS Division, deCODE genetics, Sturlugata 8, IS-101 Reykjavík, Iceland.

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http://dx.doi.org/10.1038/nature07229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687075PMC
September 2008

Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.

Am J Med Genet B Neuropsychiatr Genet 2008 Jul;147B(5):667-8

Institute for Genome Sciences and Policy, Center for Population Genomics and Pharmacogenetics, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1002/ajmg.b.30658DOI Listing
July 2008

WGAViewer: software for genomic annotation of whole genome association studies.

Genome Res 2008 Apr 6;18(4):640-3. Epub 2008 Feb 6.

Center for Population Genomics & Pharmacogenetics, Institute for Genome Sciences & Policy, Duke University, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1101/gr.071571.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279251PMC
April 2008

Potential genetic causes of heterogeneity of treatment effects.

Am J Med 2007 Apr;120(4 Suppl 1):S21-5

Center for Population Genomics and Pharmacogenetics, Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1016/j.amjmed.2007.02.004DOI Listing
April 2007

Genome-wide tagging for everyone.

Nat Genet 2006 Nov;38(11):1227-8

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http://dx.doi.org/10.1038/ng1106-1227DOI Listing
November 2006

Priorities and standards in pharmacogenetic research.

Nat Genet 2005 Jul;37(7):671-81

Institute for Genome Sciences & Policy, Center for Population Genomics & Pharmacogenetics, Duke University, 103 Research Drive, DUMC Box 3471, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/ng1593DOI Listing
July 2005

Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing.

Eur J Neurosci 2003 Sep;18(6):1640-4

Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK.

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http://dx.doi.org/10.1046/j.1460-9568.2003.02889.xDOI Listing
September 2003