Publications by authors named "Anjum Aara"

3 Publications

  • Page 1 of 1

Antioxidant activity of eugenol in leaf extract.

J Family Med Prim Care 2020 Jan 28;9(1):327-331. Epub 2020 Jan 28.

Department Oral and Maxillofacial Pathology, Faculty of Dentistry, Annamalai University, Chidambaram, Tamil Nadu, India.

Background: Extracts of Piper betel are used for the treatment of various ailments since ages due to its essential properties like antioxidant, anticancer, anti-allergic etc. In the present study antioxidant activity for Piper betel leaf extract and Eugenol was assessed. Eugenol was taken as marker compound.

Methods: Nitric oxide, Hydroxyl radical and Reducing power assay methods were carried out for assessment of antioxidant activity of Piper betel.

Results: The antioxidant activity for Nitric oxide, Hydroxyl radical and Reducing power assay at 1000 to 62.5μg/ml was performed. The antioxidant activity of Piper betel leaf extract exhibited the IC50 value for Nitric oxide and Hydroxyl radical >1000 whereas Eugenol exhibited the IC50 value 114.34± 0.46 and 306.44 ± 5.28 respectively, for reducing power assay (RPA) Piper betel leaf extract and Eugenol revealed the RPA value ranging from 0.44-0.08 and 0.53-0.12.

Conclusion: The benefits of Piper betel have been mentioned in our ancient texts. Keeping in view the emergence of various diseases and the benefits of Piper betei, there is need that every effort should be made to revive this treasure of nature into our daily supplement.
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January 2020

Primary tuberculous lymphadenitis: A case report.

Clin Cosmet Investig Dent 2010 10;2:21-5. Epub 2010 May 10.

Department of Oral Medicine and radiology, Sri Sai College of Dental Surgery, Kothrepally, Vikarabad, Andhra Pradesh, India.

Tuberculosis (TB) is a prevalent systemic bacterial infectious disease usually caused by Mycobacterium tuberculosis. It is estimated that approximately 8 million people develop TB each year, and 3 million people die of complications associated with the disease. In this article we report a case of a 17-year-old female patient with a painful swelling in her right submandibular region. She was diagnosed with right submandibular tuberculous lymphadenitis. Tuberculous lymphadenitis, when occurring in the cervical region, continues to be a common cause of extrapulmonary TB. TB is a recognized occupational risk for dentists, as they work in close proximity to the nasal and oral cavities of patients, with the possible generation of potentially infectious sprays during routine operative procedures.
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May 2013

Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: in vitro and in vivo studies.

World J Gastroenterol 2008 Apr;14(16):2566-71

Centre for Liver Research and Diagnostics, Deccan college of Medical Sciences and Allied Hospitals, Kanchanbagh, Hyderabad 500058, Andhra Pradesh, India.

Aim: To study the hepatoprotective capacity of Sapindus mukorossi (S. mukorossi) and Rheum emodi (R. emodi) extracts in CCl(4) treated male rats.

Methods: The dried powder of S. mukorossi and R. emodi was extracted successively with petroleum ether, benzene, chloroform, and ethanol and concentrated in vacuum. Primary rat hepatocyte monolayer cultures were used for in vitro studies. In vivo, the hepatoprotective capacity of the extract of the fruit pericarp of S. mukorossi and the rhizomes of R. emodi was analyzed in liver injured CCl(4)-treated male rats.

Results: In vitro: primary hepatocytes monolayer cultures were treated with CCl(4) and extracts of S. mukorossi & R. emodi. A protective activity could be demonstrated in the CCl(4) damaged primary monolayer culture. In vivo: extracts of the fruit pericarp of S. mukorossi (2.5 mg/mL) and rhizomes of R. emodi (3.0 mg/mL) were found to have protective properties in rats with CCl(4) induced liver damage as judged from serum marker enzyme activities.

Conclusion: The extracts of S. mukorossi and R. emodi do have a protective capacity both in vitro on primary hepatocytes cultures and in in vivo in a rat model of CCl(4) mediated liver injury.
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April 2008