Publications by authors named "Angelo Paci"

100Publications

Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects.

J Immunother Cancer 2020 Aug;8(2)

Molecular Radiotherapy and Innovative Therapeutics, Unité Mixte de Recherche 1030 INSERM, Gustave Roussy, F-94805, Villejuif, France

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http://dx.doi.org/10.1136/jitc-2020-000916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418776PMC
August 2020

Pharmacokinetics/Pharmacodynamic (PK/PD) relationship of therapeutic monoclonal antibodies used in oncology: what's new?

Eur J Cancer 2020 03 20;128:103-106. Epub 2020 Feb 20.

Gustave Roussy Cancer Campus, Department of Pharmacology, Villejuif, F-94805, France; University Paris-Saclay, Faculty of Pharmacy, Chatenay-Malabry, F-92290, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.01.004DOI Listing
March 2020

Pharmacokinetic/pharmacodynamic relationship of therapeutic monoclonal antibodies used in oncology: Part 2, immune checkpoint inhibitor antibodies.

Eur J Cancer 2020 03 6;128:119-128. Epub 2020 Feb 6.

University Paris-Saclay, Faculty of Pharmacy, Chatenay-Malabry, F-92290, France; Gustave Roussy Cancer Campus, Department of Pharmacology, Villejuif, F-94805, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.01.003DOI Listing
March 2020

Antidrug Antibodies Against Immune Checkpoint Blockers: Impairment of Drug Efficacy or Indication of Immune Activation?

Clin Cancer Res 2020 02 22;26(4):787-792. Epub 2019 Nov 22.

Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-2337DOI Listing
February 2020

Major pitfalls of protein kinase inhibitors prescription: A review of their clinical pharmacology for daily use.

Crit Rev Oncol Hematol 2019 Sep 16;141:112-124. Epub 2019 Jun 16.

AP-HP, Cochin Hospital, Department of gastroenterology and gastrointestinal oncology, Université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1016/j.critrevonc.2019.06.006DOI Listing
September 2019

Potentiation of mitotane action by rosuvastatin: New insights for adrenocortical carcinoma management.

Int J Oncol 2019 Jun 3;54(6):2149-2156. Epub 2019 Apr 3.

INSERM UMR‑S 1185, 94276 Le Kremlin‑Bicêtre Cedex, France.

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http://dx.doi.org/10.3892/ijo.2019.4770DOI Listing
June 2019

Intestinal bacterial β-glucuronidase as a possible predictive biomarker of irinotecan-induced diarrhea severity.

Pharmacol Ther 2019 07 1;199:1-15. Epub 2019 Mar 1.

Department of Medical Oncology, Gustave Roussy Cancer Campus, Villejuif, France; Department of Pharmacology, Gustave Roussy Cancer Campus, Villejuif, France; Department of Ambulatory Care, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1016/j.pharmthera.2019.03.002DOI Listing
July 2019

Biodegradable Pickering emulsions of Lipiodol for liver trans-arterial chemo-embolization.

Acta Biomater 2019 03 30;87:177-186. Epub 2019 Jan 30.

Institut Galien Paris-Sud, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 92296 Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.01.054DOI Listing
March 2019

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.

J Med Chem 2019 02 21;62(4):1902-1916. Epub 2018 Dec 21.

BioCIS, Université Paris-Sud, CNRS, Équipe Labellisée Ligue Contre le Cancer , Université Paris-Saclay , F-92290 Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01386DOI Listing
February 2019

Colchicine is an active treatment for everolimus-induced oral ulcers.

Eur J Cancer 2017 12 13;87:209-211. Epub 2017 Oct 13.

Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France; Department of Pharmacology, Gustave Roussy Cancer Campus, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.09.020DOI Listing
December 2017

Ultrasound-induced mild hyperthermia improves the anticancer efficacy of both Taxol® and paclitaxel-loaded nanocapsules.

J Control Release 2017 Oct 1;264:219-227. Epub 2017 Sep 1.

Institut Galien Paris-Sud, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 92296 Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.08.041DOI Listing
October 2017

Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies.

Int J Pharm 2017 Nov 22;532(2):748-756. Epub 2017 May 22.

Vectorologie des anticancéreux et des acides nucléiques, UMR 8203, CNRS, Université Paris-Sud, Gustave Roussy, Université Paris-Saclay, 94805 Villejuif, France; Service de Pharmacologie, Département de Biologie et Pathologie médicales, Gustave Roussy, 94805 Villejuif, France; Département de Pharmacocinétique & Pharmacie Clinique, Université Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 92296 Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.05.044DOI Listing
November 2017

Busulfan after HSCT in children and young adults.

Lancet Haematol 2017 03;4(3):e103

Département de Recherche Clinique, Gustave Roussy Cancer Campus, Université Paris Sud, Villejuif, France.

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http://dx.doi.org/10.1016/S2352-3026(16)30189-2DOI Listing
March 2017

Individualized Pazopanib Dosing-Letter.

Clin Cancer Res 2016 12;22(24):6298

Department of Pharmacology, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2104DOI Listing
December 2016

Early progression under mitotane and polychemotherapy does not mean failure in adrenocortical carcinoma patient.

Ann Endocrinol (Paris) 2017 Feb 22;78(1):67-69. Epub 2016 Nov 22.

Service de médecine nucléaire et de cancérologie endocrinienne, Gustave Roussy, université Paris-Saclay, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2016.10.001DOI Listing
February 2017

Safety of raltegravir-based antiretroviral therapy in HIV-infected patients receiving multi-kinase inhibitors.

Invest New Drugs 2017 04 12;35(2):247-249. Epub 2016 Nov 12.

Department of Cancer Medicine, Gustave Roussy Cancer Campus, 114, rue Edouard Vaillant, 94800, Villejuif, France.

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http://dx.doi.org/10.1007/s10637-016-0405-0DOI Listing
April 2017

Familial hematological malignancies: new IDH2 mutation.

Ann Hematol 2016 Dec 3;95(12):1943-1947. Epub 2016 Sep 3.

UR "Biologie moléculaire des leucémies et lymphomes," Laboratoire de Biochimie, Faculté de Médecine de Sousse, Université de Sousse - Tunisie, Avenue Mohamed Karoui, 4002, Sousse, Tunisia.

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http://dx.doi.org/10.1007/s00277-016-2813-9DOI Listing
December 2016

Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer.

Br J Cancer 2016 08 21;115(5):549-52. Epub 2016 Jul 21.

The Institute of Cancer Research, Clinical Pharmacology and Trials Team, London, SM2 5PT, UK.

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http://dx.doi.org/10.1038/bjc.2016.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997545PMC
August 2016

Dyslipidemia causes overestimation of plasma mitotane measurements.

Endocrinol Diabetes Metab Case Rep 2016 10;2016:150135. Epub 2016 Jun 10.

INSERM U1185, Fac Med Paris Sud, Le Kremlin-Bicêtre, France; Nuclear Medicine and Endocrine Oncology Department, Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1530/EDM-15-0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901334PMC
June 2016

Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Jun 23;1022:290-297. Epub 2016 Apr 23.

Gustave Roussy Cancer Campus Grand Paris, Service de Pharmacologie, Département de Biologie et Pathologie Médicales, Villejuif 94805, France; Université Paris-Sud, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif 94805, France; Centre National de la Recherche Scientifique (CNRS), Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif 94805, France; Gustave Roussy Cancer Campus Grand Paris, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif 94805, France. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.04.030DOI Listing
June 2016

[Tyrosine kinase inhibitors and pregnancy: A risk to the fetus?].

Bull Cancer 2016 May 8;103(5):478-83. Epub 2016 Mar 8.

Gustave-Roussy, service de pharmacologie et d'analyse du médicament, 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.02.001DOI Listing
May 2016

A case of melphalan sustained accumulation in an 80-year old patient.

Int J Clin Pharm 2015 Dec 22;37(6):984-7. Epub 2015 Sep 22.

Service de Pharmacie, Hôpital Saint-Antoine, Assistance Publique - Hôpitaux de Paris, 75012, Paris, France.

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http://link.springer.com/content/pdf/10.1007%2Fs11096-015-01
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http://link.springer.com/10.1007/s11096-015-0197-x
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http://dx.doi.org/10.1007/s11096-015-0197-xDOI Listing
December 2015

Stability of Melphalan in 0.9% Sodium Chloride Solutions Prepared in Polyvinyl Chloride Bags for Intravenous Injection.

Drugs R D 2015 Sep;15(3):253-9

Department of Clinical Pharmacy, Gustave Roussy Hospital, 114 Rue Edouard Vaillant, 94 805, Villejuif Cedex, France,

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http://dx.doi.org/10.1007/s40268-015-0098-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561048PMC
September 2015

Nilotinib versus imatinib for GIST.

Lancet Oncol 2015 Jul;16(7):e311

Gustave Roussy Cancer Campus, Villejuif, France; University Paris Descartes INSERM CIC1419, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00065-0DOI Listing
July 2015

Lipoprotein-Free Mitotane Exerts High Cytotoxic Activity in Adrenocortical Carcinoma.

J Clin Endocrinol Metab 2015 Aug 29;100(8):2890-8. Epub 2015 Jun 29.

Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche (INSERM UMR)-S 1185 (S.H., J.Y., E.B., M.L.), Le Kremlin-Bicêtre F-94276, France; Department of Nuclear Medicine and Endocrine Oncology (S.H., E.B.) and Department of Pharmacology (A.S., F.C., S.B., A.P., E.B.), Gustave Roussy, Villejuif F-94805, France; INSERM UMR-S Institute of Cardiometabolism and Nutrition/1166, (M.G., T.H.) Pitié-Salpetrière Hospital, Paris, F-75013, France; Department of Endocrinology (J.Y., M.L.), Centre Hospitalier Universitaire Bicêtre, Le Kremlin-Bicêtre F-94276, France.

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http://dx.doi.org/10.1210/JC.2015-2080DOI Listing
August 2015

Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.

J Vasc Interv Radiol 2015 Jul 4;26(7):1067-1075.e3. Epub 2015 May 4.

Departments of Neuroradiology, AP-HP Hôpital Lariboisère, Paris, France.; University Diderot-Paris 7, Paris, France.

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http://dx.doi.org/10.1016/j.jvir.2015.03.014DOI Listing
July 2015

Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study.

J Chromatogr B Analyt Technol Biomed Life Sci 2015 Jun 20;992:30-5. Epub 2015 Apr 20.

CNRS UMR 8203, Laboratory of Vectorology and Anticancer Therapeutics, Paris-Sud University, Gustave Roussy Cancer Campus Grand Paris, Villejuif, France; Pharmacology and Drug Analysis Department, Gustave Roussy Cancer Campus Grand Paris, Villejuif, France.

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http://dx.doi.org/10.1016/j.jchromb.2015.04.025DOI Listing
June 2015

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

J Med Chem 2015 Jan 23;58(2):705-17. Epub 2014 Dec 23.

Université Paris-Sud, Centre National de la Recherche Scientifique (CNRS), and Gustave Roussy Cancer Campus Grand Paris, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203 , Villejuif, France -94805.

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http://dx.doi.org/10.1021/jm501224xDOI Listing
January 2015

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies.

Eur J Cancer 2014 Aug 10;50(12):2020-36. Epub 2014 Jun 10.

Department of Pharmacy, CNRS-UMR 7054, School of Medicine Paris 12, Henri Mondor University Hospitals, Créteil, France.

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http://dx.doi.org/10.1016/j.ejca.2014.04.015DOI Listing
August 2014

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics.

Eur J Cancer 2014 Aug 2;50(12):2010-9. Epub 2014 Jun 2.

EA4553 Institut Claudius-Regaud, Université Paul-Sabatier, Toulouse, France.

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http://dx.doi.org/10.1016/j.ejca.2014.04.014DOI Listing
August 2014

Therapeutic drug monitoring in cancer--are we missing a trick?

Eur J Cancer 2014 Aug 27;50(12):2005-9. Epub 2014 May 27.

Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute/Stotervaart Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2014.04.013DOI Listing
August 2014

Stability of etoposide solutions in disposable infusion devices for day hospital cancer practices.

Drugs R D 2014 Mar;14(1):13-23

Service Interdépartemental de Pharmacologie et d'Analyse du Médicament (SIPAM), Institut Gustave-Roussy, 114, rue Edouard Vaillant, 94805, Villejuif Cedex, France.

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http://dx.doi.org/10.1007/s40268-014-0037-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964295PMC
March 2014

Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

Pediatr Blood Cancer 2014 Jun 3;61(6):1101-3. Epub 2013 Dec 3.

Pediatric and Adolescent Oncology Department, Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1002/pbc.24891DOI Listing
June 2014

Physico-chemical stability of busulfan in injectable solutions in various administration packages.

Drugs R D 2013 Mar;13(1):87-94

Pharmacology and Drug Analysis Department, Institut de Cancérologie Gustave Roussy, 114, rue Edouard Vaillant, 94805, Villejuif Cedex, France.

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http://dx.doi.org/10.1007/s40268-013-0003-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627013PMC
March 2013

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR NK cell levels correlate with disease outcome.

Oncoimmunology 2013 Feb;2(2):e23080

Institut de Cancérologie Gustave Roussy; Villejuif, France ; Centre d'Investigation Clinique Biothérapie CICBT 507; Institut de Cancérologie Gustave Roussy; Villejuif, France ; Unité de Thérapie Cellulaire; Institut de Cancérologie Gustave Roussy; Villejuif, France ; Institut National de la Santé et de la Recherche Médicale; U1015; Institut de Cancérologie Gustave Roussy; Villejuif, France.

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http://dx.doi.org/10.4161/onci.23080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601178PMC
February 2013

Comparative transplacental transfer of taxanes using the human perfused cotyledon placental model.

Am J Obstet Gynecol 2012 Dec 8;207(6):514.e1-7. Epub 2012 Oct 8.

Department of Clinical Pharmacology and Clinical Research Unit, INSERM Cliniques P 0901, Cochin Teaching Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1016/j.ajog.2012.10.007DOI Listing
December 2012

Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan.

Expert Opin Drug Metab Toxicol 2013 Mar 16;9(3):333-47. Epub 2012 Nov 16.

Collège de France, Center for Interdisciplinary Research in Biology, CNRS UMR 7241, INSERM U 1050, MEMOLIFE Laboratory of Excellence & Paris Science et Lettres Research University, Paris, France.

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http://dx.doi.org/10.1517/17425255.2013.737319DOI Listing
March 2013

Off-patent oral oncology drugs for kids (O3K FP7-project): from bedside to PUMA.

Int J Pharm 2012 Oct;435(2):148-50

Pharmacology and Drug Analysis Department, Institut de cancérologie Gustave Roussy, 114, rue Edouard Vaillant, 94805 Villejuif cedex, France.

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http://dx.doi.org/10.1016/j.ijpharm.2012.05.061DOI Listing
October 2012

Population pharmacokinetics of busulfan in children--letter.

Clin Cancer Res 2012 May;18(9):2715-6; author reply 2717-8

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http://dx.doi.org/10.1158/1078-0432.CCR-11-3297DOI Listing
May 2012

Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver tumor model.

Cardiovasc Intervent Radiol 2012 Dec 23;35(6):1448-59. Epub 2012 Feb 23.

Department of Interventional Radiology, Institute Gustave Roussy, Villejuif, 94805, France.

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http://dx.doi.org/10.1007/s00270-012-0343-yDOI Listing
December 2012

High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up.

Eur J Endocrinol 2012 Feb 2;166(2):261-8. Epub 2011 Nov 2.

Department of Nuclear Medicine and Endocrine Tumors, Institut Gustave Roussy, Univ. Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France.

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http://dx.doi.org/10.1530/EJE-11-0557DOI Listing
February 2012

Quantification of dimethyl-ifosfamide and its N-deschloropropylated metabolites in mouse plasma by liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2011 Apr 13;879(11-12):743-50. Epub 2011 Feb 13.

CNRS UMR 8203, Vectorologie et Thérapeutiques Anticancéreuses, Université Paris XI, Institut de Cancérologie Gustave Roussy, IRCIV, Villejuif, France.

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http://dx.doi.org/10.1016/j.jchromb.2011.02.012DOI Listing
April 2011

Prognostic markers of survival after combined mitotane- and platinum-based chemotherapy in metastatic adrenocortical carcinoma.

Endocr Relat Cancer 2010 Sep 16;17(3):797-807. Epub 2010 Aug 16.

Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, Villejuif Cedex, France.

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http://dx.doi.org/10.1677/ERC-09-0341DOI Listing
September 2010

Microbiological and physicochemical stability of oxycodone hydrochloride solutions for patient-controlled delivery systems.

J Pain Symptom Manage 2010 Jul 8;40(1):87-94. Epub 2010 Jun 8.

Department of Clinical Pharmacy, Institut Gustave-Roussy, Villejuif, France.

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http://linkinghub.elsevier.com/retrieve/pii/S088539241000260
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http://dx.doi.org/10.1016/j.jpainsymman.2009.11.323DOI Listing
July 2010

Oxazaphosphorines: new therapeutic strategies for an old class of drugs.

Expert Opin Drug Metab Toxicol 2010 Aug;6(8):919-38

Paris XI University and Integrated Research Cancer Institute Villejuif , France.

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http://dx.doi.org/10.1517/17425255.2010.487861DOI Listing
August 2010

Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.

Int J Pharm 2009 Sep 23;379(2):235-43. Epub 2009 May 23.

Université Paris-Sud, CNRS, UMR 8612, IFR 141, 5, rue J.B. Clément, F-92296 Châtenay-Malabry, France.

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http://dx.doi.org/10.1016/j.ijpharm.2009.05.030DOI Listing
September 2009

New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity.

J Pharmacol Exp Ther 2009 Feb 18;328(2):598-609. Epub 2008 Nov 18.

Unité Mixte de Recherche 8638 Centre National de Recherche Scientifique Medicinal Chemistry Laboratory-Faculty of Pharmacy, University Paris Descartes, Paris, France.

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http://dx.doi.org/10.1124/jpet.108.144170DOI Listing
February 2009

Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.

Drug Metab Dispos 2008 Aug 12;36(8):1570-7. Epub 2008 May 12.

Faculté de Pharmacie, Unité Mixte de Recherche Centre National de la Recherche Scientifique 8612, Institut Fédératif de Recherche 141, Université Paris XI, Châtenay-Malabry cedex, France.

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http://dx.doi.org/10.1124/dmd.108.020735DOI Listing
August 2008

Acoustic characterization of a new trisacryl contrast agent. Part II: Flow phantom study and in vivo quantification.

Ultrasonics 2008 Mar 4;48(1):26-34. Epub 2007 Dec 4.

Universite de Paris-Sud, Imaging Department and UPRES EA 4040, Orsay F-91405, Institut Gustave Roussy, 39, Rue Camille Desmoulins, 94805 Villejuif Cedex, France.

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http://www.cnuca.com/web/uca/ultrasounddata/fulltextpapers/A
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http://linkinghub.elsevier.com/retrieve/pii/S0041624X0700079
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http://dx.doi.org/10.1016/j.ultras.2007.10.006DOI Listing
March 2008

Acoustic characterization of a new trisacryl contrast agent. Part I: In vitro study.

Ultrasonics 2008 Mar 4;48(1):16-25. Epub 2007 Dec 4.

University Paris-Sud, Imaging Department and UPRES EA4040, 39 Rue Camille Desmoulins, Orsay, F-91405, Institut Gustave Roussy, 94805 Villejuif Cedex, France.

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http://dx.doi.org/10.1016/j.ultras.2007.10.007DOI Listing
March 2008

Busulphan-loaded long-circulating nanospheres, a very attractive challenge for both galenists and pharmacologists.

J Microencapsul 2007 Dec;24(8):715-30

CNRS & Université Paris XI, Pharmacotechnie, BiopharmacieChatenay Malabry, France.

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http://dx.doi.org/10.1080/02652040701500905DOI Listing
December 2007

Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography-tandem mass spectrometry in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Oct 22;858(1-2):71-8. Epub 2007 Aug 22.

UPRES EA3535 Pharmacology and New Cancer Treatments, Institute Gustave Roussy - IFR54 and Paris XI University, 94800 Villejuif, France.

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http://dx.doi.org/10.1016/j.jchromb.2007.08.018DOI Listing
October 2007

Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction.

Drug Metab Dispos 2007 Feb 28;35(2):306-14. Epub 2006 Nov 28.

Unité Propre de Recherche et de l'Enseignement Supérieur, Equipe d'Accueil 3535, Pharmacology and New Treatments of Cancers, IFR54, University Paris XI and Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1124/dmd.106.012880DOI Listing
February 2007

Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors.

Drug Metab Dispos 2006 Nov 8;34(11):1918-26. Epub 2006 Aug 8.

Unité Propre de Recherche et de l'Enseignement Supérieur, Equipe d'Accueil, Pharmacology and New Treatments of Cancer, l'Institut Fédératif de Recherches, Institute Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1124/dmd.106.010512DOI Listing
November 2006

Microbial growth tests in anti-neoplastic injectable solutions.

J Oncol Pharm Pract 2005 Mar;11(1):7-12

Department of Clinical Pharmacy, Institut Gustave-Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France.

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http://dx.doi.org/10.1191/1078155205jp143oaDOI Listing
March 2005

Liquid chromatography-tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Feb 24;832(1):67-74. Epub 2006 Jan 24.

UPRES EA3535 Pharmacology and New Cancer Treatments, Institute Gustave Roussy and Paris XI University, Villejuif, France.

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http://dx.doi.org/10.1016/j.jchromb.2005.12.037DOI Listing
February 2006

E.F.P.--European Fellowship for Pharmacists Promoting Clinical Pharmacy in Europe.

Pharm World Sci 2005 Aug;27(4):278

CHU de Reims-Fédération Pharmaceutique Unité Médicaments & Pharmacotechnie, Avenue du Général Koenig, 51092, Reims cedex, France.

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http://dx.doi.org/10.1007/s11096-005-1639-7DOI Listing
August 2005

Fluorescence detection combined with either HPLC or HPTLC for pharmaceutical quality control in a hospital chemotherapy production unit: application to camptothecin derivatives.

J Pharm Biomed Anal 2005 Sep;39(3-4):581-6

Department of Clinical Pharmacy, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94800 Villejuif, France.

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http://linkinghub.elsevier.com/retrieve/pii/S073170850500350
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http://dx.doi.org/10.1016/j.jpba.2005.05.010DOI Listing
September 2005

Quality control and stability study using HPTLC: applications to cyclophosphamide in various pharmaceutical products.

J Pharm Biomed Anal 2005 Jun;38(1):180-5

Department of Clinical Pharmacy, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94800 Villejuif, France.

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http://dx.doi.org/10.1016/j.jpba.2004.12.001DOI Listing
June 2005

High-performance thin-layer chromatography with a derivatization procedure, a suitable method for the identification and the quantitation of busulfan in various pharmaceutical products.

J Pharm Biomed Anal 2004 Feb;34(3):525-30

Department of Clinical Pharmacy, Institut Gustave Roussy, 39 Rue Camille Desmoulins, 94800 Villejuif, France.

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http://dx.doi.org/10.1016/s0731-7085(03)00630-7DOI Listing
February 2004