Andrew Oberst

Andrew Oberst

UNVERIFIED PROFILE

Are you Andrew Oberst?   Register this Author

Register author
Andrew Oberst

Andrew Oberst

Publications by authors named "Andrew Oberst"

Are you Andrew Oberst?   Register this Author

42Publications

1299Reads

41Profile Views

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.

Immunity 2019 01 8;50(1):64-76.e4. Epub 2019 Jan 8.

Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10747613183052
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2018.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342485PMC
January 2019

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.

Immunity 2019 01 8;50(1):64-76.e4. Epub 2019 Jan 8.

Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10747613183052
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2018.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342485PMC
January 2019

Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling.

J Immunol 2018 04 14;200(8):2748-2756. Epub 2018 Mar 14.

Department of Immunology, University of Washington, Seattle, WA 98109;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1701492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893403PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Programmed Cell Death and Inflammation: Winter Is Coming.

Trends Immunol 2017 10 19;38(10):705-718. Epub 2017 Jul 19.

Immunity, Inflammation, and Disease Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, Durham, NC 27709, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710799PMC
October 2017

MK2 balances inflammation and cell death.

Authors:
Andrew Oberst

Nat Cell Biol 2017 Sep;19(10):1150-1152

Department of Immunology, University of Washington, Seattle, Washington 98109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb3619DOI Listing
September 2017

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.

J Cell Biol 2017 06 21;216(6):1795-1810. Epub 2017 Apr 21.

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, TX 77030

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201608095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461015PMC
June 2017

RIPK3 in cell death and inflammation: the good, the bad, and the ugly.

Immunol Rev 2017 05;277(1):102-112

Department of Immunology, University of Washington, Seattle, WA, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/imr.12536
Publisher Site
http://dx.doi.org/10.1111/imr.12536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419046PMC
May 2017

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.

Cell 2017 Apr 30;169(2):301-313.e11. Epub 2017 Mar 30.

Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405738PMC
April 2017

Controlled detonation: evolution of necroptosis in pathogen defense.

Immunol Cell Biol 2017 02 20;95(2):131-136. Epub 2016 Dec 20.

Department of Immunology, University of Washington, Seattle, WA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/icb.2016.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855669PMC
February 2017

Necroptosis in development, inflammation and disease.

Nat Rev Mol Cell Biol 2017 02 21;18(2):127-136. Epub 2016 Dec 21.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrm.2016.149DOI Listing
February 2017

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

Science 2015 Oct 24;350(6258):328-34. Epub 2015 Sep 24.

Laboratory of Dendritic Cell Biology, Department of Immunology, Institut Pasteur, 25 Rue du Docteur Roux, 75015 Paris, France. Institut National de la Santé et de la Recherche Médicale, U818, 25 Rue du Docteur Roux, 75015 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad0395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651449PMC
October 2015

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

Science 2015 Oct 24;350(6258):328-34. Epub 2015 Sep 24.

Laboratory of Dendritic Cell Biology, Department of Immunology, Institut Pasteur, 25 Rue du Docteur Roux, 75015 Paris, France. Institut National de la Santé et de la Recherche Médicale, U818, 25 Rue du Docteur Roux, 75015 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad0395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651449PMC
October 2015

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.

Mol Cell 2015 Mar 19;57(5):860-872. Epub 2015 Feb 19.

Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2015.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352766PMC
March 2015

Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels.

Cell Rep 2014 Apr 27;7(1):45-52. Epub 2014 Mar 27.

Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.02.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992854PMC
April 2014

RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts.

Mol Cell 2011 Oct;44(1):9-16

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2011.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192321PMC
October 2011

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

Nat Rev Mol Cell Biol 2011 10 21;12(11):757-63. Epub 2011 Oct 21.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrm3214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627210PMC
October 2011

Caspase 8 inhibits programmed necrosis by processing CYLD.

Nat Cell Biol 2011 Oct 30;13(12):1437-42. Epub 2011 Oct 30.

Immunology Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229661PMC
October 2011

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.

Nature 2011 Mar 2;471(7338):363-7. Epub 2011 Mar 2.

Dept. of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature09852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077893PMC
March 2011

FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity.

Biochem J 2011 Feb;433(3):447-457

Program in Apoptosis and Cell Death Research, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20101738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024219PMC
February 2011

Live to dead cell imaging.

Methods Mol Biol 2009 ;559:33-48

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60327-017-5_3DOI Listing
October 2009

Characterization of cytoplasmic caspase-2 activation by induced proximity.

Mol Cell 2009 Sep;35(6):830-40

Department of Immunology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2009.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755603PMC
September 2009

The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.

Proc Natl Acad Sci U S A 2007 Jul 25;104(27):11280-5. Epub 2007 Jun 25.

Biochemistry Laboratory, Istituto Dermopatico dell'Immacolata-Istituto di Ricovero e Cura a Carattere Scientifico, University of Rome Tor Vergata, 00133 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0701773104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040890PMC
July 2007

The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63.

Oncogene 2005 Oct;24(46):6982-6

Department of Pathology, Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1208843DOI Listing
October 2005

Regulation of the p73 protein stability and degradation.

Biochem Biophys Res Commun 2005 Jun;331(3):707-12

IDI-IRCCS Biochemistry Lab, c/o Department of Experimental Medicine, University of Rome Tor Vergata, Rome 00133, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2005.03.158DOI Listing
June 2005

Ubiquitin-dependent degradation of p73 is inhibited by PML.

J Exp Med 2004 Jun;199(11):1545-57

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20031943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211783PMC
June 2004