Andrew J Peacock

Andrew J Peacock

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Andrew J Peacock

Publications by authors named "Andrew J Peacock"

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Multicentre trials on specialised exercise training and rehabilitation are useful in patients with pulmonary hypertension.

Eur Respir J 2019 Nov 7;54(5). Epub 2019 Nov 7.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://dx.doi.org/10.1183/13993003.01631-2019DOI Listing
November 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Pulmonary hypertension in chronic lung disease and hypoxia.

Eur Respir J 2019 Jan 24;53(1). Epub 2019 Jan 24.

University of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig University Giessen and Member of the German Center for Lung Research (DZL), Giessen, Germany.

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http://dx.doi.org/10.1183/13993003.01914-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351338PMC
January 2019

Validation of impedance cardiography in pulmonary arterial hypertension.

Clin Physiol Funct Imaging 2018 Mar 6;38(2):254-260. Epub 2017 Feb 6.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://dx.doi.org/10.1111/cpf.12408DOI Listing
March 2018

A novel single-beat approach to assess right ventricular systolic function.

J Appl Physiol (1985) 2018 02 12;124(2):283-290. Epub 2017 Oct 12.

Department of Biomedical Engineering, University of Wisconsin-Madison , Madison, Wisconsin.

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http://dx.doi.org/10.1152/japplphysiol.00258.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867365PMC
February 2018

Social deprivation and prognosis in Scottish patients with pulmonary arterial hypertension.

Eur Respir J 2018 02 31;51(2). Epub 2018 Jan 31.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://dx.doi.org/10.1183/13993003.00444-2017DOI Listing
February 2018

A study of clinical and physiological relations of daily physical activity in precapillary pulmonary hypertension.

J Appl Physiol (1985) 2017 Oct 29;123(4):851-859. Epub 2017 Jun 29.

Faculty of Physical Education and Sports Sciences, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1152/japplphysiol.00986.2016DOI Listing
October 2017

Non-invasive imaging of global and regional cardiac function in pulmonary hypertension.

Pulm Circ 2018 Jan-Mar;8(1):2045893217742000. Epub 2017 Oct 24.

41444 Cardiac and Vascular Imaging Group, Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://dx.doi.org/10.1177/2045893217742000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753990PMC
October 2017

Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

J Heart Lung Transplant 2017 Jul 31;36(7):770-779. Epub 2016 Dec 31.

National Pulmonary Hypertension Service (Newcastle), The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.12.014DOI Listing
July 2017

Measuring the effects of treatment in patients with PAH: should we image the right ventricle?

Authors:
Andrew J Peacock

Eur Respir J 2017 06 29;49(6). Epub 2017 Jun 29.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK

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http://dx.doi.org/10.1183/13993003.00805-2017DOI Listing
June 2017

Ambrisentan use for pulmonary arterial hypertension in a post-authorization drug registry: The VOLibris Tracking Study.

J Heart Lung Transplant 2017 Apr 6;36(4):399-406. Epub 2016 May 6.

Department of Experimental, Diagnostic and Specialty Medicine, Bologna University Hospital, Bologna, Italy.

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http://dx.doi.org/10.1016/j.healun.2016.04.013DOI Listing
April 2017

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.

Circulation 2017 01 21;135(5):460-475. Epub 2016 Nov 21.

From the Department of Medicine, Imperial College London, Hammersmith Campus, United Kingdom (C.J.R., P.G., J.W., K.C.R.-A., G.W., M.R.W.); Department of Medicine, University of Cambridge School of Clinical Medicine, United Kingdom (C.H., M.B., M.H., M.R.T., S.G., N.W.M.); Cardiology Department, Royal Free Hospital, London, United Kingdom (G.C.); Institute of Cellular Medicine, Newcastle University and the Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom (P.A.C.); National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom (L.S.H., J.S.R.G.); National Heart and Lung Institute, Imperial College London, Hammersmith Campus, United Kingdom (L.S.H., J.S.R.G.); Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, United Kingdom (D.G.K.); Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, United Kingdom (D.G.K., A.L.); Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom (A.J.P.); Pulmonary Vascular Disease Unit, Papworth Hospital, Cambridge, United Kingdom (J.P.Z., M.R.T.); Pulmonary Hypertension Service, Royal Brompton Hospital, London, United Kingdom (S.J.W.); and Department of Haematology, University of Cambridge, United Kingdom (S.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287439PMC
January 2017

Pulmonary vascular and cardiac impairment in interstitial lung disease.

Eur Respir Rev 2017 Jan 17;26(143). Epub 2017 Jan 17.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://err.ersjournals.com/lookup/doi/10.1183/16000617.0053-
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http://dx.doi.org/10.1183/16000617.0053-2016DOI Listing
January 2017

Imaging right ventricular function to predict outcome in pulmonary arterial hypertension.

Int J Cardiol 2016 Sep 13;218:206-211. Epub 2016 May 13.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

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http://dx.doi.org/10.1016/j.ijcard.2016.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001160PMC
September 2016

Ambrisentan for the treatment of adults with pulmonary arterial hypertension: a review.

Curr Med Res Opin 2015 27;31(9):1793-807. Epub 2015 Aug 27.

c c Pulmonary Hypertension Unit, Department of Cardiovascular and Respiratory Disease, Sapienza University of Rome , Rome , Italy.

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http://dx.doi.org/10.1185/03007995.2015.1074890DOI Listing
May 2016

Imaging the heart in pulmonary hypertension: an update.

Eur Respir Rev 2015 Dec;24(138):653-64

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK

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http://err.ersjournals.com/content/24/138/653.full.pdf
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http://err.ersjournals.com/lookup/doi/10.1183/16000617.0058-
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http://dx.doi.org/10.1183/16000617.0058-2015DOI Listing
December 2015

Severe pulmonary hypertension in lung disease: phenotypes and response to treatment.

Eur Respir J 2015 Nov 20;46(5):1378-89. Epub 2015 Aug 20.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK Both authors contributed equally

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http://dx.doi.org/10.1183/13993003.02307-2014DOI Listing
November 2015

Respiratory and limb muscle dysfunction in pulmonary arterial hypertension: a role for exercise training?

Pulm Circ 2015 Sep;5(3):424-34

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Clydebank, United Kingdom.

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http://journals.sagepub.com/doi/10.1086/682431
Publisher Site
http://dx.doi.org/10.1086/682431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556495PMC
September 2015

Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension.

N Engl J Med 2015 Aug;373(9):834-44

From the Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna, Italy (N.G.); Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer and University of Barcelona, Barcelona, and Biomedical Research Networking Center on Respiratory Diseases, Madrid (J.A.B.); Baylor College of Medicine, Houston (A.E.F.); Universities of Giessen and Marburg Lung Center, Giessen (H.-A.G.), Hanover Medical School and German Center of Lung Research, Hanover (M.M.H.), and Thoraxklinik at University Hospital Heidelberg, Heidelberg (E.G.) - all in Germany; University of Michigan Health System, Ann Arbor (V.V.M.); Regional Heart and Lung Centre, Glasgow (A.J.P.), and GlaxoSmithKline, Uxbridge (J.H.N.H., J.L.) - both in the United Kingdom; Université Paris-Sud, Faculté de Médecine, and Assistance Publique-Hôpitaux de Paris, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, INSERM Unité Mixté de Recherche S 999, Laboratoire d'Excellence en Recherche sur le Médicament et l'Innovation Thérapeutique, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson - all in France (G.S.); Universitaires de Bruxelles-Hôpital Erasme, Brussels (J.-L.V.); Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance (R.J.O.), Gilead Sciences, Foster City (C.B., H.G., K.L.M.), and University of California at San Diego, La Jolla (L.J.R.) - all in California; VU University Medical Center, Amsterdam (A.V.-N.); and the University of Rochester, Rochester, NY (R.J.W.).

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http://dx.doi.org/10.1056/NEJMoa1413687DOI Listing
August 2015

Medical Therapies for the Treatment of Pulmonary Arterial Hypertension: How Do We Choose?

Curr Hypertens Rep 2015 Jul;17(7):56

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Agamemnon Street, Clydebank, Glasgow, G81 4DY, Scotland, UK.

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http://dx.doi.org/10.1007/s11906-015-0560-2DOI Listing
July 2015

Pulmonary hypertension in POEMS syndrome: resolution following radiotherapy.

Pulm Circ 2014 Dec;4(4):732-5

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.

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http://dx.doi.org/10.1086/678553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278633PMC
December 2014

Endpoints in PAH clinical trials in the era of combination therapy: how do we decide whether something is working without going bankrupt?

Drug Discov Today 2014 Aug 9;19(8):1236-40. Epub 2014 May 9.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, G81 4HX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.04.020DOI Listing
August 2014

Cardiac magnetic resonance imaging in pulmonary arterial hypertension.

Eur Respir Rev 2013 Dec;22(130):526-34

Scottish Pulmonary Vascular Unit, Glasgow, UK. 2 Dept of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1183/09059180.00006313DOI Listing
December 2013

Pulmonary arterial hypertension: epidemiology and registries.

J Am Coll Cardiol 2013 Dec;62(25 Suppl):D51-9

Universite Paris-Sud, Inserm U999, LabEx LERMIT, AP-HP, DHU Thorax Innovation, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1016/j.jacc.2013.10.023DOI Listing
December 2013

Cellular responses to hypoxia in the pulmonary circulation.

High Alt Med Biol 2013 Jun;14(2):111-6

Scottish Pulmonary Vascular Unit, Regional Heart and Lung Center, Glasgow, United Kingdom.

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http://dx.doi.org/10.1089/ham.2013.1016DOI Listing
June 2013

Low-dose fluvastatin reverses the hypoxic pulmonary adventitial fibroblast phenotype in experimental pulmonary hypertension.

Am J Respir Cell Mol Biol 2012 Aug 1;47(2):140-8. Epub 2012 Mar 1.

Scottish Pulmonary Vascular Unit, Western Infirmary, Glasgow, Scotland, UK.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2011-0411OC
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http://dx.doi.org/10.1165/rcmb.2011-0411OCDOI Listing
August 2012

Survival in pulmonary hypertension registries: the importance of incident cases.

Chest 2011 Jun;139(6):1547-1548

Pulmonary Vascular Disease Unit, Papworth Hospital, Cambridge, England.

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http://dx.doi.org/10.1378/chest.10-3348DOI Listing
June 2011

Non-invasive stroke volume measurement by cardiac magnetic resonance imaging and inert gas rebreathing in pulmonary hypertension.

Clin Physiol Funct Imaging 2011 May 7;31(3):221-6. Epub 2011 Jan 7.

Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Clydebank, West Dunbartonshire, Scotland, UK.

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http://dx.doi.org/10.1111/j.1475-097X.2010.01004.xDOI Listing
May 2011

Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy.

Am J Respir Crit Care Med 2010 Nov 25;182(9):1171-7. Epub 2010 Jun 25.

Pulmonary Hypertension Division, Medical Clinic II/V, University Hospital Giessen und Marburg GmbH, Giessen, Germany.

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http://dx.doi.org/10.1164/rccm.201001-0123OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001259PMC
November 2010

Inhibition of p38 MAPK reverses hypoxia-induced pulmonary artery endothelial dysfunction.

Am J Physiol Heart Circ Physiol 2009 May 6;296(5):H1312-20. Epub 2009 Feb 6.

Scottish Pulmonary Vascular Unit, Level 8, Western Infirmary, Dumbarton Rd., Glasgow G11 6NT, UK.

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http://dx.doi.org/10.1152/ajpheart.00977.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685327PMC
May 2009

NT-proBNP does not rise on acute ascent to high altitude.

High Alt Med Biol 2008 ;9(4):307-10

Pulmonary Vascular Diseases Unit, Papworth Hospital, Cambridgeshire, England, UK.

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http://dx.doi.org/10.1089/ham.2008.1054DOI Listing
April 2009

Surrogate and combined end points in pulmonary arterial hypertension.

Proc Am Thorac Soc 2008 Jul;5(5):617-22

Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1513/pats.200803-029SKDOI Listing
July 2008

The relationship between the components of pulmonary artery pressure remains constant under all conditions in both health and disease.

Chest 2008 Mar 7;133(3):633-9. Epub 2007 Nov 7.

Scottish Pulmonary Vascular Unit, Western Infirmary, Dumbarton Rd, Glasgow G11 6NT, Scotland, UK.

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http://dx.doi.org/10.1378/chest.07-1367DOI Listing
March 2008

Pulmonary artery pressure in healthy subjects at 4250 m measured by Doppler echocardiography.

Wilderness Environ Med 2007 ;18(4):305-11

Department of Anesthesia, University of California, San Francisco, CA 94143-1605, USA.

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http://dx.doi.org/10.1580/07-WEME-OR-094R1.1DOI Listing
February 2008

p38 MAP kinase: essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation.

Pulm Pharmacol Ther 2007 8;20(6):718-25. Epub 2006 Sep 8.

Scottish Pulmonary Vascular Unit, Level 8, Western Infirmary, Glasgow, G11 6NT, Scotland, UK.

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http://dx.doi.org/10.1016/j.pupt.2006.08.007DOI Listing
January 2008

Pulmonary arterial pulse pressure and mortality in pulmonary arterial hypertension.

Respir Med 2007 Dec 24;101(12):2495-501. Epub 2007 Aug 24.

Scottish Pulmonary Vascular Unit, Western Infirmary, Dumbarton Road, G11 6NT Glasgow, UK.

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http://dx.doi.org/10.1016/j.rmed.2007.07.004DOI Listing
December 2007

Fluvastatin inhibits hypoxic proliferation and p38 MAPK activity in pulmonary artery fibroblasts.

Am J Respir Cell Mol Biol 2007 Oct 7;37(4):447-56. Epub 2007 Jun 7.

Scottish Pulmonary Vascular Unit, Western Infirmary, Glasgow, UK.

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http://dx.doi.org/10.1165/rcmb.2007-0012OCDOI Listing
October 2007

p38 MAP kinase isoform activity and cell cycle regulators in the proliferative response of pulmonary and systemic artery fibroblasts to acute hypoxia.

Pulm Pharmacol Ther 2006 20;19(2):128-38. Epub 2005 Jun 20.

Scottish Pulmonary Vascular Unit, Western Infirmary, Glasgow, UK.

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http://dx.doi.org/10.1016/j.pupt.2005.04.008DOI Listing
April 2006

Contrast enhanced-cardiovascular magnetic resonance imaging in patients with pulmonary hypertension.

Eur Heart J 2005 Oct 17;26(19):1993-9. Epub 2005 May 17.

Scottish Pulmonary Vascular Unit, Level 8, Western Infirmary, Glasgow G11 6NT, UK.

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http://dx.doi.org/10.1093/eurheartj/ehi328DOI Listing
October 2005

High altitude pulmonary edema triggered by vocal cord stenosis.

High Alt Med Biol 2004 ;5(4):450-2

Department of Otolaryngology, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1089/ham.2004.5.450DOI Listing
May 2005

Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter.

Am J Respir Crit Care Med 2004 Aug 15;170(3):252-9. Epub 2004 Apr 15.

Scottish Pulmonary Vascular Unit and Department of Immunology, Western Infirmary, and Institute of Biomedical and Life Sciences, University of Glasgow, Scotland, UK.

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http://dx.doi.org/10.1164/rccm.200302-264OCDOI Listing
August 2004

The genetic basis of high-altitude pulmonary oedema.

Pharmacol Ther 2004 Feb;101(2):183-92

Scottish Pulmonary Vascular Unit, Western Infirmary, Dumbarton Road, Glasgow G11 6NT, UK.

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http://dx.doi.org/10.1016/j.pharmthera.2003.11.003DOI Listing
February 2004