Andreas Laupacis

Andreas Laupacis

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Andreas Laupacis

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priorities for 2020.

Authors:
Andreas Laupacis

CMAJ 2019 Dec;191(49):E1344

Editor-in-Chief, CMAJ.

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http://dx.doi.org/10.1503/cmaj.191561DOI Listing
December 2019

Where do goals of care conversations belong? A case for the emergency department.

CJEM 2019 Nov;21(6):698-700

St. Michael's Hospital, Department of Palliative Care, Li Ka Shing Knowledge Institute, Toronto, ON.

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http://dx.doi.org/10.1017/cem.2019.364DOI Listing
November 2019

Web Exclusive. Annals Story Slam - Caring.

Authors:
Andreas Laupacis

Ann Intern Med 2019 11;171(9):SS1

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http://dx.doi.org/10.7326/W19-0021DOI Listing
November 2019

Temporal Trends of Women Enrollment in Major Cardiovascular Randomized Clinical Trials.

Can J Cardiol 2019 May 30;35(5):653-660. Epub 2019 Jan 30.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Terrence Donnelly Heart Centre, St. Michael's Hospital, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2019.01.010DOI Listing
May 2019

Trends in site of death and health care utilization at the end of life: a population-based cohort study.

CMAJ Open 2019 Apr-Jun;7(2):E306-E315. Epub 2019 Apr 26.

Departments of Critical Care Medicine (Hill, Scales, Rubenfeld, Wunsch, Dev, Fowler) and of Medicine (Gandhi, Berry), Sunnybrook Health Sciences Centre; Sunnybrook Research Institute (Hill); ICES (Stukel, Fu, Scales); Institute of Health Policy, Management and Evaluation (Stukel, Fowler), Interdepartmental Division of Critical Care (Scales, Rubenfeld, Wunsch, Dev, Fowler), Faculty of Medicine (Laupacis), Department of Anesthesia (Wunsch), Department of Medicine (Sinha, Gandhi, La Delfa), Division of Palliative Medicine, Department of Medicine (Zimmermann), and Division of Palliative Care, Department of Family Medicine, Faculty of Medicine (Myers), University of Toronto; Li Ka Shing Knowledge Institute (Laupacis) and Department of Palliative Care (La Delfa), St. Michael's Hospital, Toronto, Ont.; Departments of Medicine and Critical Care (Downar), Division of Palliative Care, University of Ottawa, Ottawa, Ont.; Divisions of Geriatric Medicine and Neurology (Rockwood), Department of Medicine, Dalhousie University, Halifax, NS; Department of Critical Care Medicine (Heyland), Queen's University, Kingston Ont.; Department of Medicine (Sinha) and Division of Palliative Care (Myers), Sinai Health System; Department of Medicine (Sinha), Division of Palliative Care, Department of Supportive Care (Zimmermann), and Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre (Ross), University Health Network, Toronto, Ont.; School of Population and Public Health (Kozak), University of British Columbia; Department of Family and Community Medicine (Kozak), Providence Health Care, Vancouver, BC.

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http://cmajopen.ca/lookup/doi/10.9778/cmajo.20180097
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http://dx.doi.org/10.9778/cmajo.20180097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488480PMC
April 2019

Intensive care utilization following major noncardiac surgical procedures in Ontario, Canada: a population-based study.

Intensive Care Med 2018 Sep 27;44(9):1427-1435. Epub 2018 Jul 27.

Department of Anesthesia and Pain Management, Toronto General Hospital, 3-EN 200 Elizabeth St, Toronto, ON, M5G 2C4, Canada.

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http://dx.doi.org/10.1007/s00134-018-5330-6DOI Listing
September 2018

Patient and Public Involvement in Identifying Dementia Research Priorities.

J Am Geriatr Soc 2018 08 7;66(8):1608-1612. Epub 2018 Aug 7.

Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1111/jgs.15453
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http://dx.doi.org/10.1111/jgs.15453DOI Listing
August 2018

Top 10 research priorities in head and neck cancer: Results of an Alberta priority setting partnership of patients, caregivers, family members, and clinicians.

Head Neck 2018 03 17;40(3):544-554. Epub 2017 Nov 17.

Steering Committee Members: Roxana Anderson, Katherine Cowan, Brock Debenham, Sharon Dixon, Tina Huizinga, Bernie Krewski, Andreas Laupacis, Leah Lechelt, Wayne Matthews, Suresh Nayar, Sandra Rees, Akhila Regunathan, Jana Rieger, Hadi Seikaly, Ameeta Singh, and Jim Traub.

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http://dx.doi.org/10.1002/hed.24998DOI Listing
March 2018

Laying the digital and analytical foundations for Canada's future health care system.

CMAJ 2018 01;190(1):E1-E2

Editorial Advisory Board member (Mamdani) CMAJ; Li Ka Shing Knowledge Institute (Mamdani, Laupacis), St. Michael's Hospital; Faculty of Medicine (Mamdani, Laupacis), University of Toronto; Institute of Health Policy, Management, and Evaluation (Mamdani, Laupacis), University of Toronto; Institute for Clinical Evaluative Sciences (Mamdani, Laupacis); Leslie Dan Faculty of Pharmacy (Mamdani), University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.170955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760252PMC
January 2018

Setting Research Priorities for Kidney Cancer.

Eur Urol 2017 12 8;72(6):861-864. Epub 2017 May 8.

Departments of Surgery and Surgical Oncology (Division of Urology), Princess Margaret Cancer Centre, University Health Network, and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.eururo.2017.04.011DOI Listing
December 2017

The kidney cancer research priority-setting partnership: Identifying the top 10 research priorities as defined by patients, caregivers, and expert clinicians.

Can Urol Assoc J 2017 Dec 1;11(12):379-387. Epub 2017 Nov 1.

Departments of Surgery and Surgical Oncology (Division of Urology), Princess Margaret Cancer Centre, University Health Network, and the University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.4590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962944PMC
December 2017

Patient characteristics, resource use and outcomes associated with general internal medicine hospital care: the General Medicine Inpatient Initiative (GEMINI) retrospective cohort study.

CMAJ Open 2017 Dec 13;5(4):E842-E849. Epub 2017 Dec 13.

Affiliations: Li Ka Shing Centre for Healthcare Analytics Research and Training (Verma, Mamdani), St. Michael's Hospital; Eliot Phillipson Clinician-Scientist Training Program (Verma), Department of Medicine, University of Toronto; Li Ka Shing Knowledge Institute (Guo, Dhalla, Hwang, Laupacis, Mamdani, Razak), St. Michael's Hospital; Department of Medicine (Kwan), Sinai Health System; Department of Medicine (Kwan, Lapointe-Shaw, Rawal, Razak, Tang, Weinerman), University of Toronto; Division of General Internal Medicine (Rawal), University Health Network; Institute for Better Health (Tang, Reid), Trillium Health Partners; Sunnybrook Health Sciences Centre (Weinerman); University Health Network, Sinai Health System (Cram), University of Toronto; Health Quality Ontario (Dhalla); Sunnybrook Health Sciences Centre (Shadowitz), University of Toronto; Bridgepoint Health (Upshur), University of Toronto, Toronto, Ont.; Harvard Center for Population and Development Studies (Razak), Cambridge, Mass.

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http://dx.doi.org/10.9778/cmajo.20170097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741428PMC
December 2017

Patients' Perspectives on Outcomes of Care After Discharge From the Emergency Department: A Qualitative Study.

Ann Emerg Med 2017 Nov 14;70(5):648-658.e2. Epub 2017 Jul 14.

Li Ka Shing Knowledge Institute, St. Michael's Hospital; Institute for Health Policy, Management and Evaluation, University of Toronto.

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http://dx.doi.org/10.1016/j.annemergmed.2017.05.034DOI Listing
November 2017

Temporal Trends in Use of Composite End Points in Major Cardiovascular Randomized Clinical Trials in Prominent Medical Journals.

Circ Cardiovasc Qual Outcomes 2017 Oct;10(10)

From the Terrence Donnelly Heart Centre, Department of Medicine, St Michael's Hospital (N.S.T., A.T.Y.), Applied Health Research Centre, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital (G.L.), Institute of Health Policy, Management and Evaluation (G.L., M.M., A.L.), The Leslie Dan Faculty of Pharmacy (M.M.), and Li Ka Shing Knowledge Institute, St Michael's Hospital (M.M., A.L.), University of Toronto, Canada; and Department of Medicine, St Mary's General Hospital, Kitchener, Canada (S.H.A.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.117.003753DOI Listing
October 2017

A qualitative study of emergency physicians' perspectives on PROMS in the emergency department.

BMJ Qual Saf 2017 Sep 9;26(9):714-721. Epub 2017 Feb 9.

St Michael's Hospital, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjqs-2016-006012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574389PMC
September 2017

Priority setting in paediatric preventive care research.

Arch Dis Child 2017 08 12;102(8):748-753. Epub 2017 Apr 12.

Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1136/archdischild-2016-312284DOI Listing
August 2017

Finding the right balance between precision medicine and personalized care.

CMAJ 2017 08;189(33):E1065-E1068

Division of General Internal Medicine (McAlister), Faculty of Medicine and Dentistry, University of Alberta; Canadian VIGOUR Centre, Department of Medicine - Cardiology (McAlister, Armstrong), University of Alberta, Edmonton, Alta.; St. Michael's Hospital and Faculty of Medicine (Laupacis), University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.170107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566606PMC
August 2017

Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children.

JAMA 2017 Jul;318(3):245-254

Department of Pediatrics, St Michael's Hospital, Pediatric Research, Toronto, Ontario, Canada2Pediatric Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, the Hospital for Sick Children, Toronto, Ontario, Canada3Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada4Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada8The La Ka Shing Knowledge Institute of St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.2017.8708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817430PMC
July 2017

Engaging Patients and Clinicians in Establishing Research Priorities for Gestational Diabetes Mellitus.

Can J Diabetes 2017 Apr 21;41(2):156-163. Epub 2016 Nov 21.

School of Public Health, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcjd.2016.08.219DOI Listing
April 2017

Meta-analysis of timing of endovascular aneurysm treatment in subarachnoid haemorrhage: inconsistent results of early treatment within 1 day.

J Neurol Neurosurg Psychiatry 2017 Mar 18;88(3):241-248. Epub 2017 Jan 18.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2016-314596
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http://dx.doi.org/10.1136/jnnp-2016-314596DOI Listing
March 2017

Development of a preliminary essential medicines list for Canada.

CMAJ Open 2017 Jan-Mar;5(1):E137-E143. Epub 2017 Feb 16.

Faculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20160122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378503PMC
February 2017

Potential Cost-Effectiveness of Ambulatory Cardiac Rhythm Monitoring After Cryptogenic Stroke.

Stroke 2016 09 28;47(9):2380-5. Epub 2016 Jul 28.

From the Centre for Excellence in Economic Analysis Research (CLEAR), Toronto, ON, Canada (J.H.E.Y, J.S.H.); Applied Health Research Centre, Toronto, ON, Canada (K.E.T.); HUB Research Solutions, Li Ka Shing Centre for Healthcare Analytics Research and Training (LKS-CHART) (M.M.), Li Ka Shing Knowledge Institute, Toronto, ON, Canada (A.L.); St. Michael's Hospital, Toronto, ON, Canada (P.D.); Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital; School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa; Institute of Clinical and Evaluative Sciences (ICES UOttawa), ON, Canada (K.T.); Institute of Health Policy, Management, and Evaluation (J.S.H., M.M., A.L.), Dalla Lana School of Public Health (K.E.T.), Leslie Dan Faculty of Pharmacy (J.S.H., M.M.), Division of Neurology (D.J.G.), and Department of Medicine (M.M., P.D., A.L., D.J.G.), University of Toronto, ON, Canada; Department of Public Health Sciences and Center for Healthcare Policy and Research, University of California, Davis, CA (J.S.H.); Division of Neurology, Department of Medicine, McMaster University, Hamilton, ON, Canada (M.S.); and Division of Neurology, Department of Medicine, Hurvitz Brain Sciences Program, and Regional Stroke Centre, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, ON, Canada (D.J.G.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011979DOI Listing
September 2016

Predictors of diagnostic neuroimaging delays among adults presenting with symptoms suggestive of acute stroke in Ontario: a prospective cohort study.

CMAJ Open 2016 Apr-Jun;4(2):E331-7. Epub 2016 Jun 20.

Institute of Health Policy, Management and Evaluation (Burton, Kapral, Krahn, Laupacis), University of Toronto; Departments of Medical Imaging (Burton, Moody) and Medicine (Kapral, Krahn, Laupacis), University of Toronto; Institute for Clinical Evaluative Sciences (Kapral, Li, Fang); Institute of Medical Sciences (Moody), University of Toronto; Toronto Health Economics and Technology Assessment Collaborative (Krahn), University of Toronto; Li Ka Shing Knowledge Institute (Laupacis), St. Michael's Hospital, Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20150110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933639PMC
July 2016

Immune Sensitization and Mortality in Wait-Listed Kidney Transplant Candidates.

J Am Soc Nephrol 2016 Feb 8;27(2):570-8. Epub 2015 Jun 8.

Division of Nephrology and the Kidney Transplant Program, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada; Institute of Health Policy, Management, and Evaluation, and Division of Nephrology, Departments of Medicine and Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1681/ASN.2014090894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731107PMC
February 2016

Early Cholecystectomy for Acute Cholecystitis Offers the Best Outcomes at the Least Cost: A Model-Based Cost-Utility Analysis.

J Am Coll Surg 2016 Feb 25;222(2):185-94. Epub 2015 Nov 25.

Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, Canada; Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada; Institute for Clinical Evaluative Sciences, Toronto, Canada; Faculty of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jamcollsurg.2015.10.015DOI Listing
February 2016

Determining research priorities through partnership with patients: an overview.

Semin Dial 2015 Mar-Apr;28(2):141-6. Epub 2014 Nov 30.

Department of Medicine, University of Calgary, Calgary, Alberta, Canada; Interdisciplinary Chronic Disease Collaboration, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/sdi.12325DOI Listing
December 2015

Public engagement in Ontario's hospitals--opportunities and challenges.

Healthc Q 2012 ;15 Spec No:16-20

Member of the Department of Medicine, University of Toronto; the Li Ka Shing Knowledge Institute of St. Michael's Hospital; and the Institute for Clinical Evaluative Sciences.

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http://dx.doi.org/10.12927/hcq.2012.23159DOI Listing
November 2015

Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores.

Stroke 2015 Nov 13;46(11):3105-10. Epub 2015 Oct 13.

From the Division of Neuroradiology and Department of Medical Imaging (T.J.H., R.I.A., S.P.S.) and Division of Neurology, Department of Medicine and Brain Sciences Program (D.J.G.), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada; Calgary Stroke Program, Department of Clinical Neurosciences, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada (M.D.H., A.M.D.); Department of Medicine (Neurology) (D.D.) and Department of Diagnostic Imaging, Neuroradiology Section, The Ottawa Hospital (C.L.), University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Canada; Department of Medicine and Institute of Health Policy Management and Evaluation, University of Toronto and Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada (A.L.); Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada (A.K.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital and Vall d'Hebron Research Institute, Barcelona, Spain (C.A.M., D.R.-L.); Department Neurology, Elblandklinikum Meissen, Academic Teaching Hospital of University of Dresden, Meissen, Germany (I.D.); Department of Neurology, Dr Josep Trueta University Hospital, Institut d'Investigació Biomèdica Girona (IDIBGi) Foundation, Girona, Spain (Y.S.); Second Department of Neurology, Institute of Psychiatry and Neurology of Warsaw, Warsaw, Poland (A.K.); Department of Medicine, Charles LeMoyne Hospital, University of Sherbrooke, Montreal, Canada (J.-M.B.); Division of Neurology, Department of Medicine, Dalhousie University, Halifax, Canada (G.G.); Department of Neurology, All India Institute of Medical Sciences, New Delhi, India (R.B., V.P.); Department of Neuromedicine, AMRI Hospitals, Mukundapur, Kolkata, India (J.R.); and Department of Neurology, Boston Medical Center, MA (C.S.K.).

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http://stroke.ahajournals.org/content/46/11/3105.full.pdf
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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.115.009893DOI Listing
November 2015

Prevalence of Body Mass Index Lower Than 16 Among Women in Low- and Middle-Income Countries.

JAMA 2015 Nov;314(20):2164-71

Harvard Centre for Population and Development Studies, Harvard University, Cambridge, Massachusetts.

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http://dx.doi.org/10.1001/jama.2015.15666DOI Listing
November 2015

Assessing the extent to which current clinical research is consistent with patient priorities: a scoping review using a case study in patients on or nearing dialysis.

Can J Kidney Health Dis 2015 1;2:35. Epub 2015 Oct 1.

University of Calgary, Cumming School of Medicine, Division of Nephrology, Health Sciences Building, 3330 Hospital Drive NW, Calgary, T2N 4N1 AB Canada ; Department of Community Health Sciences, University of Calgary, Calgary, AB Canada.

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http://dx.doi.org/10.1186/s40697-015-0070-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590701PMC
October 2015

Preoperative testing before low-risk surgical procedures.

CMAJ 2015 Aug 1;187(11):E349-E358. Epub 2015 Jun 1.

Department of Anesthesia and Pain Management (Kirkham), Toronto Western Hospital, University of Toronto, Toronto, Ont.; Department of Anesthesia (Kirkham) and Institute for Health System Solutions and Virtual Care (Pendrith, Bhatia), Women's College Hospital, Toronto, Ont.; Li Ka Shing Knowledge Institute (Wijeysundera, Laupacis), St. Michael's Hospital, Toronto, Ont.; Department of Anesthesia and Pain Management (Wijeysundera), Toronto General Hospital, University of Toronto, Toronto, Ont.; Department of Medicine (Wijeysundera, Tu, Laupacis, Schull, Levinson), University of Toronto, Toronto, Ont.; Institute for Clinical Evaluative Sciences (Ng, Tu, Laupacis, Schull, Bhatia), Toronto, Ont.; Division of Cardiology (Tu), Sunnybrook Schulich Heart Centre, Toronto, Ont.; Sunnybrook Research Institute (Schull), Toronto, Ont.; Division of Cardiology (Bhatia), University Health Network, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.150174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527930PMC
August 2015

Views of Canadian patients on or nearing dialysis and their caregivers: a thematic analysis.

Can J Kidney Health Dis 2014 7;1. Epub 2014 Apr 7.

Department of Medicine, University of Calgary, Calgary, Alberta Canada ; Interdisciplinary Chronic Disease Collaboration, Kragujevac, Alberta Canada ; Department of Community Health Sciences, University of Calgary, Calgary, Canada ; Libin Cardiovascular Institute and Institute of Public Health, University of Calgary, Calgary, Canada ; Foothills Medical Centre, 1403 29th St., NW, Calgary, Alberta T2N 2T9 Canada.

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http://dx.doi.org/10.1186/2054-3581-1-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346298PMC
March 2015

A systematic review of the role of C4d in the diagnosis of acute antibody-mediated rejection.

Kidney Int 2015 Jan 14;87(1):182-94. Epub 2014 May 14.

1] Division of Nephrology and the Kidney Transplant Program, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada [2] Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada [3] Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada [4] Division of Nephrology and the Renal Transplant Program, St Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ki.2014.166DOI Listing
January 2015

The evidence, ethics and politics of mandatory health care worker vaccination.

J Health Serv Res Policy 2015 Jan 11;20(1):1-3. Epub 2014 Sep 11.

Executive Director, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Faculty of Medicine, University of Toronto, Canada.

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http://dx.doi.org/10.1177/1355819614546960DOI Listing
January 2015

Perfusion CT for selecting patients with acute ischemic stroke for intravenous thrombolytic therapy.

Radiology 2015 Jan 19;274(1):103-14. Epub 2014 Sep 19.

From the Institute for Health Policy, Management and Evaluation (K.R.B., M.K.K., A.L.), Department of Medical Imaging (K.R.B., R.I.A., A.R.M.), Institute of Medical Sciences (R.I.A., A.R.M.), and Department of Medicine (M.K.K., A.L.), University of Toronto, 263 McCaul St, 4th Floor, Toronto, ON, Canada M5T 1W7; Department of Medical Imaging, Fraser Health Authority, Vancouver, British Columbia, Canada (D.D.); Department of Medical Imaging, University of British Columbia, Vancouver, British Columbia, Canada (D.D.); Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (M.K.K.); and Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (A.L.).

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http://dx.doi.org/10.1148/radiol.14140728DOI Listing
January 2015

Setting research priorities for patients on or nearing dialysis.

Clin J Am Soc Nephrol 2014 Oct 15;9(10):1813-21. Epub 2014 May 15.

Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2215/CJN.01610214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186509PMC
October 2014

Effect of a postdischarge virtual ward on readmission or death for high-risk patients: a randomized clinical trial.

JAMA 2014 Oct;312(13):1305-12

Department of Medicine, University of Toronto, Toronto, Ontario, Canada2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto4Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto5Institute for Clinical Evaluati.

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http://www.gim.utoronto.ca/Assets/GIM+Digital+Assets/VW+JAMA
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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
Publisher Site
http://dx.doi.org/10.1001/jama.2014.11492DOI Listing
October 2014

The Ontario Drug Policy Research Network: bridging the gap between Research and Drug Policy.

Health Policy 2014 Sep 8;117(3):392-8. Epub 2014 Jul 8.

Li KaShing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada; Department of Medicine, St. Michael's Hospital, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada; Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.healthpol.2014.06.007DOI Listing
September 2014

Printed educational messages aimed at family practitioners fail to increase retinal screening among their patients with diabetes: a pragmatic cluster randomized controlled trial [ISRCTN72772651].

Implement Sci 2014 Aug 6;9:87. Epub 2014 Aug 6.

Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, 1465 Richmond Street, London, Ontario N6A 3K7, Canada.

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http://dx.doi.org/10.1186/1748-5908-9-87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261896PMC
August 2014

Atrial fibrillation in patients with cryptogenic stroke.

N Engl J Med 2014 Jun;370(26):2467-77

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., A.L., M.S., J.A.B., L.K.C., D.S., M. Mehdiratta, K.B., M.K.K.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, the University of Toronto Stroke Program (D.J.G.), Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute (D.J.G., R.A.), the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (D.J.G.), and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital (V.P., K.E.T., J.H., H.V., A.L., M. Mamdani), Toronto, McMaster University, Hamilton, ON (M.S., D.J.S.), McGill University, Montreal (R.C.), University of Alberta, Edmonton (A.S., B.B.), Western University, London, ON (V.H., J.D.S.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB (S.B.C.), University of British Columbia, Vancouver (P.T., S.Y.), Queen's University, Kingston, ON (A.J.), Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON (D.H.), Université Laval, Quebec City (S.V.), and Vancouver Island Health Research Centre, Victoria, BC (A.P.) - all in Canada; and the National University of Ireland, Galway (M.O.).

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http://dx.doi.org/10.1056/NEJMoa1311376DOI Listing
June 2014

Systematic review, critical appraisal, and analysis of the quality of economic evaluations in stroke imaging.

Stroke 2014 Mar 11;45(3):807-14. Epub 2014 Feb 11.

From the Institute of Health Policy, Management and Evaluation (K.R.B., N.P., M.K.K., M.D.K., A.L.), Departments of Medical Imaging (K.R.B., R.I.A., A.R.M.), Surgery, Division of Urology (N.P.), Institute of Medical Science (R.I.A., A.R.M.), Medicine (M.K.K., M.D.K., A.L.), and Toronto Health Economics and Technology Assessment Collaborative (M.D.K.), University of Toronto, Toronto, ON, Canada; Institute for Clinical and Evaluative Sciences, Toronto, ON, Canada (M.K.K.); and Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada (A.L.).

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.113.004027
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http://dx.doi.org/10.1161/STROKEAHA.113.004027DOI Listing
March 2014

Comparative operative outcomes of early and delayed cholecystectomy for acute cholecystitis: a population-based propensity score analysis.

Ann Surg 2014 Jan;259(1):10-5

*Sunnybrook Research Institute, Sunnybrook Health Sciences Center †Li Ka Shing Knowledge Institute, St Michael's Hospital; and ‡Institute for Clinical Evaluative Sciences, Toronto, Canada.

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http://dx.doi.org/10.1097/SLA.0b013e3182a5cf36DOI Listing
January 2014

Impact of provider volume on operative mortality after radical cystectomy in a publicly funded healthcare system.

Can Urol Assoc J 2013 Nov-Dec;7(11-12):425-9

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON; ; Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, ON; ; Institute for Clinical Evaluative Sciences, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876442PMC
January 2014

Randomized feasibility study of de-escalated (every 12 wk) versus standard (every 3 to 4 wk) intravenous pamidronate in women with low-risk bone metastases from breast cancer.

Am J Clin Oncol 2013 Oct;36(5):436-42

*Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Hospital ‡Ambulatory Care, Princess Margaret Hospital §Toronto General Research Institute, University of Toronto and University Health Network ∥Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto †Department of Medical Oncology, R.S. McLaughlin Durham Regional Cancer Centre, Oshawa ¶Division of Medical Oncology, University of Ottawa and The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.

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http://dx.doi.org/10.1097/COC.0b013e3182568f7aDOI Listing
October 2013

Higher surgeon and hospital volume improves long-term survival after radical cystectomy.

Cancer 2013 Oct 9;119(19):3546-54. Epub 2013 Jul 9.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.28235DOI Listing
October 2013

What do letters to the editor publish about randomized controlled trials? A cross-sectional study.

BMC Res Notes 2013 Oct 14;6:414. Epub 2013 Oct 14.

Li Ka Shing Knowledge Institute (LKSKI) of St, Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/1756-0500-6-414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852599PMC
October 2013

Early cholecystectomy for acute cholecystitis: a population-based retrospective cohort study of variation in practice.

CMAJ Open 2013 May 16;1(2):E62-7. Epub 2013 May 16.

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont. ; Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ont. ; Institute for Clinical Evaluative Sciences, Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20130001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985913PMC
May 2013

Toward safer transitions: how can we reduce post-discharge adverse events?

Healthc Q 2012 ;15 Spec No:63-7

Department of Medicine, University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.12927/hcq.2012.22839DOI Listing
January 2013

SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.

BMJ 2013 Jan 8;346:e7586. Epub 2013 Jan 8.

Women's College Research Institute at Women's College Hospital, Department of Medicine, University of Toronto, Toronto, Canada M5G 1N8.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541470PMC
http://dx.doi.org/10.1136/bmj.e7586DOI Listing
January 2013

Systematic review and evaluation of web-accessible tools for management of diabetes and related cardiovascular risk factors by patients and healthcare providers.

J Am Med Inform Assoc 2012 Jul-Aug;19(4):514-22. Epub 2012 Jan 3.

Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1136/amiajnl-2011-000307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384097PMC
December 2012

Public payments to physicians in Ontario adjusted for overhead costs.

Healthc Policy 2012 Nov;8(2):30-6

Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517870PMC
November 2012

The average lifespan of patients discharged from hospital with heart failure.

J Gen Intern Med 2012 Sep 2;27(9):1171-9. Epub 2012 May 2.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s11606-012-2072-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515002PMC
September 2012

Radial artery and saphenous vein patency more than 5 years after coronary artery bypass surgery: results from RAPS (Radial Artery Patency Study).

J Am Coll Cardiol 2012 Jul;60(1):28-35

Division of Cardiac and Vascular Surgery and Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2012.03.037DOI Listing
July 2012

Designing and evaluating a web-based self-management site for patients with type 2 diabetes--systematic website development and study protocol.

BMC Med Inform Decis Mak 2012 Jun 24;12:57. Epub 2012 Jun 24.

Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, 30 Bond Street, Toronto, ON M5B 1W8, Canada.

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http://dx.doi.org/10.1186/1472-6947-12-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473319PMC
June 2012

Patient and physician predictors of peritoneal dialysis technique failure: a population based, retrospective cohort study.

Perit Dial Int 2011 Sep-Oct;31(5):565-73. Epub 2010 Oct 14.

Institute for Clinical Evaluative Sciences, University Health Network and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3747/pdi.2010.00096DOI Listing
February 2012

Variation in the practice of preoperative medical consultation for major elective noncardiac surgery: a population-based study.

Anesthesiology 2012 Jan;116(1):25-34

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/ALN.0b013e31823cfc03DOI Listing
January 2012

Evaluation of CT and MRI scanning among cancer patients in Ontario.

Clin Imaging 2011 Jul-Aug;35(4):301-8

Institute for Clinical Evaluative Sciences, 2075 Bayview Ave., Toronto, Ontario, Canada M4N 3M5.

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http://dx.doi.org/10.1016/j.clinimag.2010.07.007DOI Listing
December 2011

Clinical prediction rules for children: a systematic review.

Pediatrics 2011 Sep 22;128(3):e666-77. Epub 2011 Aug 22.

Department of Pediatrics, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.

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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2011-0043DOI Listing
September 2011

Selection bias explains apparent differential mortality between dialysis modalities.

J Am Soc Nephrol 2011 Aug 22;22(8):1534-42. Epub 2011 Jul 22.

University of Calgary, Foothills Medical Centre, Calgary, Alberta, T2N 2T9 Canada.

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http://dx.doi.org/10.1681/ASN.2010121232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148708PMC
August 2011

The rise of people power.

Nature 2011 Apr;472(7344):410-1

Memorial University of Newfoundland, St John's, Newfoundland and Labrador A1B 3V6, Canada.

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http://dx.doi.org/10.1038/472410aDOI Listing
April 2011

Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women.

JAMA 2011 Feb;305(8):783-9

Institute for Clinical Evaluative Sciences, and Li Ka Shing Knowledge Institute of St. Michael's Hospital, 30 Bond St, Toronto, Ontario, M5B 1W8.

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http://dx.doi.org/10.1001/jama.2011.190DOI Listing
February 2011

Accepting new patients: What does the public think about Ontario's policy?

Can Fam Physician 2011 Feb;57(2):e68-73

Memorial University of Newfoundland, Division of Pediatrics, 300 Prince Phillip Dr, St John's, NL A1B 3V6; e-mail

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038835PMC
February 2011

Patterns of care and outcomes after computed tomography scans for headache.

Am J Med 2011 Jan 19;124(1):58-63.e1. Epub 2010 Oct 19.

Departments of Medicine and of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.amjmed.2010.08.010DOI Listing
January 2011

How to use an article about quality improvement.

JAMA 2010 Nov;304(20):2279-87

Division of Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, 1830 E Monument St, Fifth Floor, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1001/jama.2010.1692DOI Listing
November 2010