Ana M Valdes

Ana M Valdes

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Ana M Valdes

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Metabolic syndrome and osteoarthritis pain: common molecular mechanisms and potential therapeutic implications.

Authors:
Ana M Valdes

Osteoarthritis Cartilage 2019 Aug 10. Epub 2019 Aug 10.

School of Medicine, University of Nottingham; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals, NHS Trust. Electronic address:

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http://dx.doi.org/10.1016/j.joca.2019.06.015DOI Listing
August 2019

The Metabolomic Signatures of Weight Change.

Metabolites 2019 Apr 4;9(4). Epub 2019 Apr 4.

Department of Twin Research, King's College London, London SE1 7EH, UK.

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https://www.mdpi.com/2218-1989/9/4/67
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http://dx.doi.org/10.3390/metabo9040067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523676PMC
April 2019

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity.

Gut Microbes 2019 Apr 29:1-8. Epub 2019 Apr 29.

a Department of Twin Research and Genetic Epidemiology , King's College London , London , UK.

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http://dx.doi.org/10.1080/19490976.2019.1586038DOI Listing
April 2019

Inflammatory markers and mediators in heart disease.

Aging (Albany NY) 2018 Nov;10(11):3061-3062

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.

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http://dx.doi.org/10.18632/aging.101640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286839PMC
November 2018

Familial aggregation and heritability of type 1 diabetes mellitus and coaggregation of chronic diseases in affected families.

Clin Epidemiol 2018 10;10:1447-1455. Epub 2018 Oct 10.

Division or Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK,

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http://dx.doi.org/10.2147/CLEP.S172207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186906PMC
October 2018

Big data boost for osteoarthritis genetics.

Nat Rev Rheumatol 2018 07;14(7):387-388

Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/s41584-018-0023-7DOI Listing
July 2018

Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes.

Nat Rev Rheumatol 2018 06;14(6):327-340

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1038/s41584-018-0001-0DOI Listing
June 2018

Role of the gut microbiota in nutrition and health.

BMJ 2018 Jun 13;361:k2179. Epub 2018 Jun 13.

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000740PMC
http://dx.doi.org/10.1136/bmj.k2179DOI Listing
June 2018

First validation of the gout activity score against gout impact scale in a primary care based gout cohort.

Joint Bone Spine 2018 May 17;85(3):323-325. Epub 2017 May 17.

Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, NG5 1PB Nottingham, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2017.05.010DOI Listing
May 2018

Genetic and microbiome influence on lipid metabolism and dyslipidemia.

Physiol Genomics 2018 02 20;50(2):117-126. Epub 2017 Dec 20.

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, Westminster Bridge Road, London , United Kingdom.

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http://dx.doi.org/10.1152/physiolgenomics.00053.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867613PMC
February 2018

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Authors:
Xia Jiang Paul F O'Reilly Hugues Aschard Yi-Hsiang Hsu J Brent Richards Josée Dupuis Erik Ingelsson David Karasik Stefan Pilz Diane Berry Bryan Kestenbaum Jusheng Zheng Jianan Luan Eleni Sofianopoulou Elizabeth A Streeten Demetrius Albanes Pamela L Lutsey Lu Yao Weihong Tang Michael J Econs Henri Wallaschofski Henry Völzke Ang Zhou Chris Power Mark I McCarthy Erin D Michos Eric Boerwinkle Stephanie J Weinstein Neal D Freedman Wen-Yi Huang Natasja M Van Schoor Nathalie van der Velde Lisette C P G M de Groot Anke Enneman L Adrienne Cupples Sarah L Booth Ramachandran S Vasan Ching-Ti Liu Yanhua Zhou Samuli Ripatti Claes Ohlsson Liesbeth Vandenput Mattias Lorentzon Johan G Eriksson M Kyla Shea Denise K Houston Stephen B Kritchevsky Yongmei Liu Kurt K Lohman Luigi Ferrucci Munro Peacock Christian Gieger Marian Beekman Eline Slagboom Joris Deelen Diana van Heemst Marcus E Kleber Winfried März Ian H de Boer Alexis C Wood Jerome I Rotter Stephen S Rich Cassianne Robinson-Cohen Martin den Heijer Marjo-Riitta Jarvelin Alana Cavadino Peter K Joshi James F Wilson Caroline Hayward Lars Lind Karl Michaëlsson Stella Trompet M Carola Zillikens Andre G Uitterlinden Fernando Rivadeneira Linda Broer Lina Zgaga Harry Campbell Evropi Theodoratou Susan M Farrington Maria Timofeeva Malcolm G Dunlop Ana M Valdes Emmi Tikkanen Terho Lehtimäki Leo-Pekka Lyytikäinen Mika Kähönen Olli T Raitakari Vera Mikkilä M Arfan Ikram Naveed Sattar J Wouter Jukema Nicholas J Wareham Claudia Langenberg Nita G Forouhi Thomas E Gundersen Kay-Tee Khaw Adam S Butterworth John Danesh Timothy Spector Thomas J Wang Elina Hyppönen Peter Kraft Douglas P Kiel

Nat Commun 2018 01 17;9(1):260. Epub 2018 Jan 17.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-02662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772647PMC
January 2018

Association between ultrasound-detected synovitis and knee pain: a population-based case-control study with both cross-sectional and follow-up data.

Arthritis Res Ther 2017 Dec 19;19(1):281. Epub 2017 Dec 19.

Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1186/s13075-017-1486-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738097PMC
December 2017

Triggers of acute attacks of gout, does age of gout onset matter? A primary care based cross-sectional study.

PLoS One 2017 12;12(10):e0186096. Epub 2017 Oct 12.

Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186096PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638318PMC
October 2017

Neuropathic pain-like symptoms and pre-surgery radiographic severity contribute to patient satisfaction 4.8 years post-total joint replacement.

World J Orthop 2017 Oct 18;8(10):761-769. Epub 2017 Oct 18.

Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham NG5 1PB, United Kingdom.

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http://dx.doi.org/10.5312/wjo.v8.i10.761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656491PMC
October 2017

Association of Beta-Blocker Use With Less Prevalent Joint Pain and Lower Opioid Requirement in People With Osteoarthritis.

Arthritis Care Res (Hoboken) 2017 07 7;69(7):1076-1081. Epub 2017 Jun 7.

University of Nottingham, Nottingham City Hospital, and Arthritis Research UK Pain Centre, Nottingham, UK.

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http://dx.doi.org/10.1002/acr.23091DOI Listing
July 2017

Mitochondrial DNA haplogroups and ageing mechanisms in osteoarthritis.

Ann Rheum Dis 2017 06 9;76(6):939-941. Epub 2017 Jan 9.

Hospital for Special Surgery, HSS Research Institute, New York, New York, USA.

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http://dx.doi.org/10.1136/annrheumdis-2016-210783DOI Listing
June 2017

Mixing omics: combining genetics and metabolomics to study rheumatic diseases.

Nat Rev Rheumatol 2017 Mar 2;13(3):174-181. Epub 2017 Feb 2.

The Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.5DOI Listing
March 2017

Genetic association studies in osteoarthritis: is it fairytale?

Curr Opin Rheumatol 2017 01;29(1):103-109

aAcademic Rheumatology, University of Nottingham bArthritis Research UK Pain Centre, Nottingham, UK.

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http://pdfs.journals.lww.com/co-rheumatology/2017/01000/Gene
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http://dx.doi.org/10.1097/BOR.0000000000000352DOI Listing
January 2017

Association of Serum Uric Acid and Disease Duration With Frequent Gout Attacks: A Case-Control Study.

Arthritis Care Res (Hoboken) 2016 10 2;68(10):1573-7. Epub 2016 Sep 2.

University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1002/acr.22855DOI Listing
October 2016

Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health.

Obesity (Silver Spring) 2016 06 30;24(6):1380-8. Epub 2016 Apr 30.

Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.

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http://dx.doi.org/10.1002/oby.21488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914926PMC
June 2016

Low omega-3 fatty acid levels associate with frequent gout attacks: a case control study.

Ann Rheum Dis 2016 Apr 29;75(4):784-5. Epub 2015 Dec 29.

Academic Rheumatology, University of Nottingham, Nottingham, UK.

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http://ard.bmj.com/content/75/4/784.full.pdf
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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2015-20876
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http://dx.doi.org/10.1136/annrheumdis-2015-208767DOI Listing
April 2016

Use of prescription analgesic medication and pain catastrophizing after total joint replacement surgery.

Semin Arthritis Rheum 2015 Oct 20;45(2):150-5. Epub 2015 May 20.

Academic Rheumatology, Nottingham City Hospital, Clinical Sciences Building, Hucknall Rd, Nottingham NG5 1PB, UK; Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1016/j.semarthrit.2015.05.004DOI Listing
October 2015

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families.

JAMA Intern Med 2015 Sep;175(9):1518-26

Division of Rheumatology, Orthopaedics, and Dermatology, School of Medicine, University of Nottingham, Nottingham, England.

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http://dx.doi.org/10.1001/jamainternmed.2015.3528DOI Listing
September 2015

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate.

Hypertension 2015 Aug 1;66(2):422-9. Epub 2015 Jun 1.

From the Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom (C.M., M.M., M.P., T.D.S., A.M.V.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (D.G., N.H.J.A., S.M.A., M.M.B., A.F.D., S.P.); Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Germany (G.K., K.S.); Faculty of Medicine, University of Southampton, Southampton, United Kingdom (P.T., M.H.E., C.C.); Wellcome Trust Sanger Institute Human Genetics, Hinxton, United Kingdom (S.-Y.S., N.S.); MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom (S.-Y.S.); Chemical Analytics, Seibersdorf Labor GmbH, Seibersdorf, Austria (T.G., A.H., C.R.); Institute of Epidemiology II, Helmholtz Zentrum München, Germany (A.P., C.G.); Research Unit Molecular Epidemiology, Helmholtz Zentrum München, Germany (A.P., R.W.-S., T.X.); Cardiovascular and Metabolic Diseases, Pfizer Worldwide Research and Development, Cambridge, MA (M.J.B.); Edison Pharmaceuticals, Mountain View, CA (J.T.); Metabolon, Inc, Durham, NC (R.P.M.); Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom (C.C.); Scottish Pulmonary Vascular Unit, Golden jubilee Hospital, Glasgow, United Kingdom (A.C.C.); Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, Qatar (K.S.); and Academic Rheumatology, University of Nottingham, Nottingham, United Kingdom (A.M.V.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490909PMC
August 2015

Metabolomic study of carotid-femoral pulse-wave velocity in women.

J Hypertens 2015 Apr;33(4):791-6; discussion 796

aDepartment of Twin Research and Genetic Epidemiology bDepartment of Clinical Pharmacology, King's College London, London, UK cPfizer Worldwide Research and Development, Cambridge, Massachusetts dEdison Pharmaceuticals, Mountain View, California eMetabalon, Inc., Durham, North Carolina, USA fInstitute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow gAcademic Rheumatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1097/HJH.0000000000000467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354457PMC
April 2015

Cardiovascular disease and osteoarthritis: common pathways and patient outcomes.

Eur J Clin Invest 2015 Apr 20;45(4):405-14. Epub 2015 Feb 20.

Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1111/eci.12413DOI Listing
April 2015

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

Ann Rheum Dis 2015 Feb 21;74(2):369-74. Epub 2013 Nov 21.

Department of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20406
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http://dx.doi.org/10.1136/annrheumdis-2013-204067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316854PMC
February 2015

SMAD3 is associated with the total burden of radiographic osteoarthritis: the Chingford study.

PLoS One 2014 22;9(5):e97786. Epub 2014 May 22.

Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada; Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097786PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031234PMC
January 2015

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.

Ann Rheum Dis 2014 Dec 29;73(12):2130-6. Epub 2013 Aug 29.

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK Department of Academic Rheumatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-203114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251181PMC
December 2014

Variants close to NTRK2 gene are associated with birth weight in female twins.

Twin Res Hum Genet 2014 Aug 20;17(4):254-61. Epub 2014 Jun 20.

Department of Twin Research and Genetic Epidemiology,King's College London,St Thomas' Hospital,London,UK.

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http://dx.doi.org/10.1017/thg.2014.34DOI Listing
August 2014

History of knee surgery is associated with higher prevalence of neuropathic pain-like symptoms in patients with severe osteoarthritis of the knee.

Semin Arthritis Rheum 2014 Apr 8;43(5):588-92. Epub 2013 Oct 8.

Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital Hucknall Road, Nottingham NG5 1PB, UK.

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http://dx.doi.org/10.1016/j.semarthrit.2013.10.001DOI Listing
April 2014

The genetic contribution to severe post-traumatic osteoarthritis.

Ann Rheum Dis 2013 Oct 26;72(10):1687-90. Epub 2013 Jan 26.

Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-202562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786638PMC
October 2013

Receiver operating characteristic analysis of HLA, CTLA4, and insulin genotypes for type 1 diabetes.

Diabetes Care 2013 Sep 29;36(9):2504-7. Epub 2013 Apr 29.

Academic Rheumatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.2337/dc12-2284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747897PMC
September 2013

HLA class II genotyping of African American type 1 diabetic patients reveals associations unique to African haplotypes.

Diabetes 2013 Sep 25;62(9):3292-9. Epub 2013 Jun 25.

Children's Hospital Oakland Research Institute, Oakland, California, USA.

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http://dx.doi.org/10.2337/db13-0094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749336PMC
September 2013

Omics technologies and the study of human ageing.

Nat Rev Genet 2013 Sep 13;14(9):601-7. Epub 2013 Aug 13.

1] Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK. [2] Academic Rheumatology, University of Nottingham, Nottingham NG5 1PB, UK.

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http://dx.doi.org/10.1038/nrg3553DOI Listing
September 2013

Metabolomic markers reveal novel pathways of ageing and early development in human populations.

Int J Epidemiol 2013 Aug 8;42(4):1111-9. Epub 2013 Jul 8.

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK, Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg, Germany, Pfizer Research Laboratories, Groton, CT, USA, Worldwide R&D, Pfizer Inc., Cambridge, MA, USA, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia, Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK, Metabolon Inc., 617 Davis Drive, Durham, NC 27713, USA; Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, State of Qatar and Academic Rheumatology, University of Nottingham, Nottingham City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1093/ije/dyt094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781000PMC
August 2013

Prediction of type 1 diabetes.

Diabetes 2013 Apr;62(4):1020-1

Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.2337/db12-1593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609574PMC
April 2013

Identification of seven loci affecting mean telomere length and their association with disease.

Authors:
Veryan Codd Christopher P Nelson Eva Albrecht Massimo Mangino Joris Deelen Jessica L Buxton Jouke Jan Hottenga Krista Fischer Tõnu Esko Ida Surakka Linda Broer Dale R Nyholt Irene Mateo Leach Perttu Salo Sara Hägg Mary K Matthews Jutta Palmen Giuseppe D Norata Paul F O'Reilly Danish Saleheen Najaf Amin Anthony J Balmforth Marian Beekman Rudolf A de Boer Stefan Böhringer Peter S Braund Paul R Burton Anton J M de Craen Matthew Denniff Yanbin Dong Konstantinos Douroudis Elena Dubinina Johan G Eriksson Katia Garlaschelli Dehuang Guo Anna-Liisa Hartikainen Anjali K Henders Jeanine J Houwing-Duistermaat Laura Kananen Lennart C Karssen Johannes Kettunen Norman Klopp Vasiliki Lagou Elisabeth M van Leeuwen Pamela A Madden Reedik Mägi Patrik K E Magnusson Satu Männistö Mark I McCarthy Sarah E Medland Evelin Mihailov Grant W Montgomery Ben A Oostra Aarno Palotie Annette Peters Helen Pollard Anneli Pouta Inga Prokopenko Samuli Ripatti Veikko Salomaa H Eka D Suchiman Ana M Valdes Niek Verweij Ana Viñuela Xiaoling Wang H-Erich Wichmann Elisabeth Widen Gonneke Willemsen Margaret J Wright Kai Xia Xiangjun Xiao Dirk J van Veldhuisen Alberico L Catapano Martin D Tobin Alistair S Hall Alexandra I F Blakemore Wiek H van Gilst Haidong Zhu Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Philippa J Talmud Nancy L Pedersen Markus Perola Willem Ouwehand Jaakko Kaprio Nicholas G Martin Cornelia M van Duijn Iiris Hovatta Christian Gieger Andres Metspalu Dorret I Boomsma Marjo-Riitta Jarvelin P Eline Slagboom John R Thompson Tim D Spector Pim van der Harst Nilesh J Samani

Nat Genet 2013 Apr;45(4):422-7, 427e1-2

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

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http://www.ideal-ageing.eu/uploads/publicaties/2013_codd_nat
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http://www.nature.com/doifinder/10.1038/ng.2528
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http://dx.doi.org/10.1038/ng.2528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006270PMC
April 2013

Cohort Profile: TwinsUK and healthy ageing twin study.

Int J Epidemiol 2013 Feb 9;42(1):76-85. Epub 2012 Jan 9.

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, London, UK.

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https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/
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http://dx.doi.org/10.1093/ije/dyr207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600616PMC
February 2013

Genetic contribution to radiographic severity in osteoarthritis of the knee.

Ann Rheum Dis 2012 Sep 21;71(9):1537-40. Epub 2012 May 21.

Correspondence to Dr Ana M Valdes, Kings College London, Twin Research Unit, St Thomas Hospital, Lambeth Palace Rd, London SE1 7EH, UK.

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http://ard.bmj.com/content/71/9/1537.full.pdf
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http://ard.bmj.com/cgi/doi/10.1136/annrheumdis-2012-201382
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http://dx.doi.org/10.1136/annrheumdis-2012-201382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414227PMC
September 2012

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

Lancet 2012 Sep 3;380(9844):815-23. Epub 2012 Jul 3.

Wellcome Trust Sanger Institute, Morgan Building, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://linkinghub.elsevier.com/retrieve/pii/S014067361260681
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http://dx.doi.org/10.1016/S0140-6736(12)60681-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443899PMC
September 2012

Genetic factors in OA pathogenesis.

Bone 2012 Aug 8;51(2):258-64. Epub 2011 Dec 8.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.bone.2011.11.026DOI Listing
August 2012

Variants in the genes encoding TNF-α, IL-10, and GSTP1 influence the effect of α-tocopherol on inflammatory cell responses in healthy men.

Am J Clin Nutr 2012 Jun 9;95(6):1461-7. Epub 2012 May 9.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, IDS Building, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.3945/ajcn.111.012781DOI Listing
June 2012

Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty.

Semin Arthritis Rheum 2012 Feb 24;41(4):568-75. Epub 2011 Aug 24.

Department of Twin Research, King's College London, St. Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1016/j.semarthrit.2011.07.002DOI Listing
February 2012

Genetics of the HLA region in the prediction of type 1 diabetes.

Curr Diab Rep 2011 Dec;11(6):533-42

Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA.

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http://dx.doi.org/10.1007/s11892-011-0223-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233362PMC
December 2011

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

Ann Rheum Dis 2011 Feb 10;70(2):349-55. Epub 2010 Nov 10.

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.

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http://dx.doi.org/10.1136/ard.2010.132787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615180PMC
February 2011

Genetic epidemiology of hip and knee osteoarthritis.

Nat Rev Rheumatol 2011 Jan 16;7(1):23-32. Epub 2010 Nov 16.

Department of Twin Research & Genetic Epidemiology, St. Thomas' Hospital, Kings College London School of Medicine, London SE1 7EH, UK.

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http://dx.doi.org/10.1038/nrrheum.2010.191DOI Listing
January 2011