Allan Vaag

Allan Vaag

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Allan Vaag

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Type 2 diabetes remission 1 year after an intensive lifestyle intervention: A secondary analysis of a randomized clinical trial.

Diabetes Obes Metab 2019 Jun 5. Epub 2019 Jun 5.

Centre of Inflammation and Metabolism and Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/dom.13802DOI Listing
June 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Prospective study of gestational diabetes and fatty liver scores 9 to 16 years after pregnancy.

J Diabetes 2019 Apr 19. Epub 2019 Apr 19.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1753-0407.12
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http://dx.doi.org/10.1111/1753-0407.12934DOI Listing
April 2019

In utero exposure to extra vitamin D from food fortification and the risk of subsequent development of gestational diabetes: the D-tect study.

Nutr J 2018 11 2;17(1):100. Epub 2018 Nov 2.

Research Unit for Dietary Studies at The Parker Institute Bispebjerg and Frederiksberg Hospital, part of the Copenhagen University Hospital - The capital Region, Nordre Fasanvej 57, vej 8, entrance 11, 2000, Frederiksberg, Denmark.

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http://dx.doi.org/10.1186/s12937-018-0403-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215342PMC
November 2018

Fish Intake in Pregnancy and Offspring Metabolic Parameters at Age 9⁻16-Does Gestational Diabetes Modify the Risk?

Nutrients 2018 Oct 17;10(10). Epub 2018 Oct 17.

Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, DK-2300 Copenhagen, Denmark.

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http://dx.doi.org/10.3390/nu10101534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213471PMC
October 2018

Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations.

Diabetologia 2018 08 12;61(8):1758-1768. Epub 2018 Jun 12.

Division of Intramural Population Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, 6710 Rockledge Dr, Bethesda, MD, 20817, USA.

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http://dx.doi.org/10.1007/s00125-018-4637-8DOI Listing
August 2018

Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.

BMC Med Genomics 2018 Aug 8;11(1):64. Epub 2018 Aug 8.

Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1186/s12920-018-0380-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083526PMC
August 2018

Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy.

Diabetes Care 2018 07 4;41(7):1378-1384. Epub 2018 May 4.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.2337/dc17-2629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014536PMC
July 2018

Perspectives on diabetes mortality as the result of residual confounding and reverse causality by common disease.

Diabetes Obes Metab 2018 06 25;20(6):1342-1349. Epub 2018 Feb 25.

Cardiovascular and Metabolic Disease (CVMD) Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/dom.13238DOI Listing
June 2018

Telomere length is reduced in 9- to 16-year-old girls exposed to gestational diabetes in utero.

Diabetologia 2018 04 23;61(4):870-880. Epub 2018 Jan 23.

Department of Endocrinology (Diabetes and Metabolism), Section 7652, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00125-018-4549-7DOI Listing
April 2018

MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism?

Eur J Endocrinol 2018 Apr 25;178(4):R113-R125. Epub 2018 Jan 25.

Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1530/EJE-17-0832DOI Listing
April 2018

Plasma ceramide levels are altered in low and normal birth weight men in response to short-term high-fat overfeeding.

Sci Rep 2018 02 22;8(1):3452. Epub 2018 Feb 22.

Department of Endocrinology, Diabetes and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41598-018-21419-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823847PMC
February 2018

36 h fasting of young men influences adipose tissue DNA methylation of and in a birth weight-dependent manner.

Clin Epigenetics 2017 21;9:40. Epub 2017 Apr 21.

Epigenetics and Diabetes and Islet Cell Exocytosis, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Jan Waldentröms gata 35, SE-20502 Malmö, Sweden.

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http://dx.doi.org/10.1186/s13148-017-0340-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399392PMC
January 2018

Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations.

J Clin Endocrinol Metab 2018 01;103(1):115-124

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1210/jc.2017-01438DOI Listing
January 2018

Dnmt3a is an epigenetic mediator of adipose insulin resistance.

Elife 2017 11 1;6. Epub 2017 Nov 1.

Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States.

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http://dx.doi.org/10.7554/eLife.30766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730374PMC
November 2017

Ponderal index at birth associates with later risk of gestational diabetes mellitus.

Arch Gynecol Obstet 2017 Aug 17;296(2):249-256. Epub 2017 Jun 17.

Department of Gynecology and Obstetrics, Copenhagen University Hospital Herlev, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00404-017-4427-4DOI Listing
August 2017

Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes.

Mol Metab 2017 07 27;6(7):770-779. Epub 2017 Apr 27.

The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen Denmark.

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http://dx.doi.org/10.1016/j.molmet.2017.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485225PMC
July 2017

Diagnosing gestational diabetes mellitus in the Danish National Birth Cohort.

Acta Obstet Gynecol Scand 2017 May 9;96(5):563-569. Epub 2017 Feb 9.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA.

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http://dx.doi.org/10.1111/aogs.13083DOI Listing
May 2017

Childhood body mass index and development of type 2 diabetes throughout adult life-A large-scale danish cohort study.

Obesity (Silver Spring) 2017 05 27;25(5):965-971. Epub 2017 Mar 27.

Department of Clinical Epidemiology (formerly the Institute of Preventive Medicine), Bispebjerg and Frederiksberg Hospitals, The Capital Region, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/oby.21820DOI Listing
May 2017

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men.

Sci Rep 2017 04 27;7(1):1235. Epub 2017 Apr 27.

Rigshospitalet, Faculty of Health and Medical Sciences University of Copenhagen, Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Copenhagen N, 2200, Denmark.

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http://dx.doi.org/10.1038/s41598-017-01382-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430872PMC
April 2017

A retrospective analysis of a societal experiment among the Danish population suggests that exposure to extra doses of vitamin A during fetal development may lower type 2 diabetes mellitus (T2DM) risk later in life.

Br J Nutr 2017 Mar 27;117(5):731-736. Epub 2017 Mar 27.

1Research Unit for Dietary Studies,The Parker Institute and Department of Clinical Epidemiology (formerly 'Institute of Preventive Medicine'),Bispebjerg and Frederiksberg University Hospitals - the Capital Region,Nordre Fasanvej 57, Hovedvejen, entrance 5, ground floor, 2000 Frederiksberg,Denmark.

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http://dx.doi.org/10.1017/S000711451700037XDOI Listing
March 2017

EMPA-REG: Glucose excretion and lipid mobilization - not storage - saves lives.

J Diabetes Complications 2016 May-Jun;30(4):753. Epub 2016 Feb 23.

Department of Endocrinology, Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jdiacomp.2016.02.015DOI Listing
January 2017

Epigenetic programming of adipose-derived stem cells in low birthweight individuals.

Diabetologia 2016 12 14;59(12):2664-2673. Epub 2016 Sep 14.

Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet - Section 7652, Tagensvej 20, DK-2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00125-016-4099-9DOI Listing
December 2016

Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes.

Epigenomics 2016 12 17;8(12):1601-1617. Epub 2016 Nov 17.

Department of Endocrinology, Diabetes & Metabolism, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.2217/epi-2016-0077DOI Listing
December 2016

Plasma amino acid levels are elevated in young, healthy low birth weight men exposed to short-term high-fat overfeeding.

Physiol Rep 2016 12;4(23)

Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.14814/phy2.13044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260087PMC
December 2016

Gene Expression and DNA Methylation of PPARGC1A in Muscle and Adipose Tissue From Adult Offspring of Women With Diabetes in Pregnancy.

Diabetes 2016 10 7;65(10):2900-10. Epub 2016 Jul 7.

Center for Pregnant Women with Diabetes, Rigshospitalet, Copenhagen, Denmark Department of Obstetrics, Rigshospitalet, Copenhagen, Denmark Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.2337/db16-0227DOI Listing
October 2016

Genome-wide associations for birth weight and correlations with adult disease.

Authors:
Momoko Horikoshi Robin N Beaumont Felix R Day Nicole M Warrington Marjolein N Kooijman Juan Fernandez-Tajes Bjarke Feenstra Natalie R van Zuydam Kyle J Gaulton Niels Grarup Jonathan P Bradfield David P Strachan Ruifang Li-Gao Tarunveer S Ahluwalia Eskil Kreiner Rico Rueedi Leo-Pekka Lyytikäinen Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Jouke-Jan Hottenga Natalia Vilor-Tejedor Peter K Joshi Eileen Tai Hui Boh Ioanna Ntalla Niina Pitkänen Anubha Mahajan Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Michael Nodzenski Louise A Diver Krina T Zondervan Mariona Bustamante Pedro Marques-Vidal Josep M Mercader Amanda J Bennett Nilufer Rahmioglu Dale R Nyholt Ronald Ching Wan Ma Claudia Ha Ting Tam Wing Hung Tam Santhi K Ganesh Frank Ja van Rooij Samuel E Jones Po-Ru Loh Katherine S Ruth Marcus A Tuke Jessica Tyrrell Andrew R Wood Hanieh Yaghootkar Denise M Scholtens Lavinia Paternoster Inga Prokopenko Peter Kovacs Mustafa Atalay Sara M Willems Kalliope Panoutsopoulou Xu Wang Lisbeth Carstensen Frank Geller Katharina E Schraut Mario Murcia Catharina Em van Beijsterveldt Gonneke Willemsen Emil V R Appel Cilius E Fonvig Caecilie Trier Carla Mt Tiesler Marie Standl Zoltán Kutalik Sílvia Bonas-Guarch David M Hougaard Friman Sánchez David Torrents Johannes Waage Mads V Hollegaard Hugoline G de Haan Frits R Rosendaal Carolina Medina-Gomez Susan M Ring Gibran Hemani George McMahon Neil R Robertson Christopher J Groves Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Frank D Mentch Scott M MacKenzie Rebecca M Reynolds William L Lowe Anke Tönjes Michael Stumvoll Virpi Lindi Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Thorkild Ia Sørensen Harri Niinikoski Katja Pahkala Olli T Raitakari Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Mads Melbye Harry Campbell James F Wilson Martine Vrijheid Eco Jcn de Geus Dorret I Boomsma Haja N Kadarmideen Jens-Christian Holm Torben Hansen Sylvain Sebert Andrew T Hattersley Lawrence J Beilin John P Newnham Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Mika Kähönen Jorma S Viikari Terho Lehtimäki Peter Vollenweider Klaus Bønnelykke Hans Bisgaard Dennis O Mook-Kanamori Albert Hofman Fernando Rivadeneira André G Uitterlinden Charlotta Pisinger Oluf Pedersen Christine Power Elina Hyppönen Nicholas J Wareham Hakon Hakonarson Eleanor Davies Brian R Walker Vincent Wv Jaddoe Marjo-Riitta Jarvelin Struan Fa Grant Allan A Vaag Debbie A Lawlor Timothy M Frayling George Davey Smith Andrew P Morris Ken K Ong Janine F Felix Nicholas J Timpson John Rb Perry David M Evans Mark I McCarthy Rachel M Freathy

Nature 2016 10 28;538(7624):248-252. Epub 2016 Sep 28.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/nature19806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164934PMC
October 2016

Criterion validity and reliability of a smartphone delivered sub-maximal fitness test for people with type 2 diabetes.

BMC Sports Sci Med Rehabil 2016 7;8:31. Epub 2016 Oct 7.

Centre for Physical Activity Research, Finsen Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1186/s13102-016-0056-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290632PMC
October 2016

Disproportionately increased 24-h energy expenditure and fat oxidation in young men with low birth weight during a high-fat overfeeding challenge.

Eur J Nutr 2016 Sep 22;55(6):2045-52. Epub 2015 Aug 22.

Steno Diabetes Center, Niels Steensens Vej 2, 2820, Gentofte, Denmark.

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http://dx.doi.org/10.1007/s00394-015-1018-7DOI Listing
September 2016

Endocrine and metabolic diurnal rhythms in young adult men born small vs appropriate for gestational age.

Eur J Endocrinol 2016 Jul;175(1):29-40

Department of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark Steno Diabetes CenterGentofte, Denmark.

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http://dx.doi.org/10.1530/EJE-16-0177DOI Listing
July 2016

Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects.

J Clin Endocrinol Metab 2016 05 22;101(5):2254-64. Epub 2016 Mar 22.

Department of Endocrinology, Diabetes, and Metabolism (N.S.H., L.H., C.B., L.G., M.S., S.W.J., A.V.), Rigshospitalet, 2200 Copenhagen, Denmark; Faculty of Health and Medical Sciences (N.S.H., L.H., A.V.) University of Copenhagen, 1165 Copenhagen, Denmark; The Danish Diabetes Academy (L.H.), 5000 Odense, Denmark; Steno Diabetes Center A/S (B.M., S.W.J.), 2820 Gentofte, Denmark; The August Center (M.F., J.F.P.W.), Department of Nutrition, Exercise, and Sports, University of Copenhagen, 2200 Copenhagen, Denmark; The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research (B.K.P.), Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, 2200 Copenhagen, Denmark; Center for Diabetes Research (B.M.), Gentofte Hospital, University of Copenhagen, 2200 Copenhagen, Denmark; and Novo Nordisk A/S (H.S.S.), 2880 Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2015-4214DOI Listing
May 2016

Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study.

PLoS One 2015 1;10(6):e0128631. Epub 2015 Jun 1.

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospitals, The Capital Region, Frederiksberg, Denmark; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, The Capital Region, Frederiksberg, Denmark; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark; Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, University of Sydney, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128631PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452099PMC
April 2016

Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Diabetologia 2016 Apr 11;59(4):799-812. Epub 2016 Jan 11.

Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University, Jan Waldenströms gata 35, SE-20502, Malmö, Sweden.

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http://dx.doi.org/10.1007/s00125-015-3852-9DOI Listing
April 2016

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.

Nat Commun 2016 Mar 31;7:11089. Epub 2016 Mar 31.

Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, CRC 91:12, Jan Waldenströms gata 35, 20502 Malmö, Sweden.

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http://dx.doi.org/10.1038/ncomms11089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821875PMC
March 2016

Parental smoking during pregnancy and the risk of gestational diabetes in the daughter.

Int J Epidemiol 2016 Feb 9;45(1):160-9. Epub 2016 Jan 9.

Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA,

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http://dx.doi.org/10.1093/ije/dyv334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881834PMC
February 2016

Microchimerism of male origin in a cohort of Danish girls.

Chimerism 2015 Oct 11;6(4):65-71. Epub 2016 Aug 11.

d University of Copenhagen , Department of Public Health , Copenhagen , Denmark.

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http://dx.doi.org/10.1080/19381956.2016.1218583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293315PMC
October 2015

No evidence of seasonality of birth in adult type 2 diabetes in Denmark.

Diabetologia 2015 Sep 16;58(9):2045-50. Epub 2015 Jun 16.

Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Nordre Fasanvej 57, Hovedvejen, Entrance 5, 2000, Frederiksberg, Denmark,

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http://dx.doi.org/10.1007/s00125-015-3661-1DOI Listing
September 2015

Prevalence and risk factors of gestational diabetes in Punjab, North India: results from a population screening program.

Eur J Endocrinol 2015 Aug 26;173(2):257-67. Epub 2015 May 26.

Deep Hospital481-Model Town, Ludhiana, Punjab, IndiaDepartment of Clinical SciencesDiabetes and Endocrinology, Clinical Research Centre, Lund University, Malmö, SwedenDepartment of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark Deep Hospital481-Model Town, Ludhiana, Punjab, IndiaDepartment of Clinical SciencesDiabetes and Endocrinology, Clinical Research Centre, Lund University, Malmö, SwedenDepartment of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1530/EJE-14-0428DOI Listing
August 2015

WITHDRAWN: Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus.

Cochrane Database Syst Rev 2015 Jul 29(7):CD008143. Epub 2015 Jul 29.

Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 7812, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark, DK-2100.

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http://dx.doi.org/10.1002/14651858.CD008143.pub4DOI Listing
July 2015

WITHDRAWN: Sulphonylurea monotherapy for patients with type 2 diabetes mellitus.

Cochrane Database Syst Rev 2015 Jul 29(7):CD009008. Epub 2015 Jul 29.

Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 7812, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark, DK-2100.

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http://dx.doi.org/10.1002/14651858.CD009008.pub3DOI Listing
July 2015

Long-term risk of type 2 diabetes mellitus in relation to BMI and weight change among women with a history of gestational diabetes mellitus: a prospective cohort study.

Diabetologia 2015 Jun 22;58(6):1212-9. Epub 2015 Mar 22.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 6100 Executive Boulevard, Rockville, MD, 20852, USA.

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http://dx.doi.org/10.1007/s00125-015-3537-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629783PMC
June 2015

Impaired cerebral blood flow and oxygenation during exercise in type 2 diabetic patients.

Physiol Rep 2015 Jun;3(6)

Department of Internal Medicine, AMC Center for Heart Failure Research Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands Department of Anatomy, Embryology & Physiology, AMC Center for Heart Failure Research Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands Laboratory for Clinical Cardiovascular Physiology, AMC Center for Heart Failure Research Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands MRC/Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Life Sciences University of Nottingham Medical School Queen's Medical Centre, Nottingham, UK

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http://dx.doi.org/10.14814/phy2.12430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510631PMC
June 2015

Carotid intima-media thickness is reduced 12 months after gastric bypass surgery in obese patients with type 2 diabetes or impaired glucose tolerance.

J Diabetes Complications 2014 Jul-Aug;28(4):517-22. Epub 2014 Mar 12.

Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark; Department of Medicine F, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark.

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http://dx.doi.org/10.1016/j.jdiacomp.2014.03.005DOI Listing
February 2015

Sulfonylurea in combination with insulin is associated with increased mortality compared with a combination of insulin and metformin in a retrospective Danish nationwide study.

Diabetologia 2015 Jan 10;58(1):50-8. Epub 2014 Sep 10.

The Heart Centre, Department of Cardiology, University Hospital Rigshospitalet, 9441, Blegdamsvej 9, 2100, Copenhagen, Denmark,

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http://dx.doi.org/10.1007/s00125-014-3372-zDOI Listing
January 2015

Metabolic response to 36 hours of fasting in young men born small vs appropriate for gestational age.

Diabetologia 2015 Jan 7;58(1):178-87. Epub 2014 Oct 7.

Department of Endocrinology (Diabetes and Metabolism), Rigshospitalet, Tagensvej 20, 2200, Copenhagen N, Denmark,

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http://dx.doi.org/10.1007/s00125-014-3406-6DOI Listing
January 2015

Rationale, design, and method of the Diabetes & Women's Health study--a study of long-term health implications of glucose intolerance in pregnancy and their determinants.

Acta Obstet Gynecol Scand 2014 Nov 9;93(11):1123-30. Epub 2014 Jun 9.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA.

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http://dx.doi.org/10.1111/aogs.12425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205761PMC
November 2014

Genetic, nongenetic and epigenetic risk determinants in developmental programming of type 2 diabetes.

Acta Obstet Gynecol Scand 2014 Nov 30;93(11):1099-108. Epub 2014 Sep 30.

Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet University Hospital/Copenhagen University, Copenhagen, Denmark; Department of Clinical Sciences, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1111/aogs.12494DOI Listing
November 2014

Physical inactivity affects skeletal muscle insulin signaling in a birth weight-dependent manner.

J Diabetes Complications 2014 Jan-Feb;28(1):71-8. Epub 2013 Oct 10.

Steno Diabetes Center, Gentofte, Denmark; Rigshospitalet, Department of Endocrinology, Denmark.

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http://dx.doi.org/10.1016/j.jdiacomp.2013.09.002DOI Listing
August 2014

Association of heart failure severity with risk of diabetes: a Danish nationwide cohort study.

Diabetologia 2014 Aug 22;57(8):1595-600. Epub 2014 May 22.

Department of Cardiology-post 635, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900, Hellerup, Denmark,

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http://dx.doi.org/10.1007/s00125-014-3259-zDOI Listing
August 2014

Targeting intensive versus conventional glycaemic control for type 1 diabetes mellitus: a systematic review with meta-analyses and trial sequential analyses of randomised clinical trials.

BMJ Open 2014 Aug 19;4(8):e004806. Epub 2014 Aug 19.

Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 7812, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1136/bmjopen-2014-004806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139659PMC
August 2014

Physical activity and sedentary behaviors associated with risk of progression from gestational diabetes mellitus to type 2 diabetes mellitus: a prospective cohort study.

JAMA Intern Med 2014 Jul;174(7):1047-55

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland.

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http://dx.doi.org/10.1001/jamainternmed.2014.1795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209161PMC
July 2014

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.

Proc Natl Acad Sci U S A 2014 Jul 30;111(28):10305-10. Epub 2014 Jun 30.

Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark,Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; and

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http://dx.doi.org/10.1073/pnas.1402571111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104872PMC
July 2014

Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.

J Clin Endocrinol Metab 2014 Jun 11;99(6):2198-207. Epub 2014 Mar 11.

Department of Paediatrics (A.T., D.C., M.L.M., K.M., D.B.D.) and Wolfson Brain Imaging Centre (A.S.), University of Cambridge, CB2 0QQ, Cambridge, United Kingdom; Medical Research Council (MRC) Metabolic Diseases Unit (G.S.H.Y.), University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, United Kingdom; MRC Human Nutrition Research of Growth and Reproduction (L.B.); and National Institute for Health Research Cambridge Comprehensive Biomedical Research Centre (D.B.D.), Cambridge, CB1 9NL, United Kingdom; Department of Endocrinology (S.W.J., A.V.), Rigshospitalet and Copenhagen University, DK-2100 Denmark; Oxford Centre for Diabetes, Endocrinology, and Metabolism (N.R.H.), University of Oxford, Oxford, OX3 7LE, United Kingdom; and Department of Growth and Reproduction (A.J.), Rigshospitalet, Faculty of Health and Medical Sciences, DK-2100 Denmark.

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http://dx.doi.org/10.1210/jc.2013-4542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413372PMC
June 2014

Prepregnancy low-carbohydrate dietary pattern and risk of gestational diabetes mellitus: a prospective cohort study.

Am J Clin Nutr 2014 Jun 9;99(6):1378-84. Epub 2014 Apr 9.

From the Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Rockville, MD (WB, MK, and CZ); the Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (KB); the Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA (DKT and JC); the Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (SFO); the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (JC); and the Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark (AV).

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http://dx.doi.org/10.3945/ajcn.113.082966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021782PMC
June 2014

[In Process Citation].

Ugeskr Laeger 2014 Jun;176(11A)

Jens Steen Nielsen, DD2-Centret, Odense Universitetshospital, Kløvervænget 10, 3. sal, 5000 Odense C.

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June 2014

Subclinical inflammation during third trimester of pregnancy was not associated with markers of the metabolic syndrome in young adult offspring.

Obesity (Silver Spring) 2014 May 5;22(5):1351-8. Epub 2013 Dec 5.

Department of Medical Endocrinology, Rigshospitalet, Copenhagen, Denmark; Department of Epidemiology Research, Statens Serum Institute, Artillerivej 5, 2300 S, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/oby.20650DOI Listing
May 2014

PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects--impact of 5 days of high-fat overfeeding.

Metabolism 2014 Feb 23;63(2):263-71. Epub 2013 Oct 23.

Department of Endocrinology, Rigshospitalet, Tagensvej 20, DK-2200 Copenhagen, Denmark; Steno Diabetes Center, Niels Steensensvej 2, DK-2820 Gentofte, Denmark; Department of Clinical Sciences, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden; Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.metabol.2013.10.003DOI Listing
February 2014

Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight.

Diabetes 2014 Jan 23;63(1):111-21. Epub 2013 Sep 23.

Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.2337/db13-0621DOI Listing
January 2014

Treating allergic rhinitis with depot-steroid injections increase risk of osteoporosis and diabetes.

Respir Med 2013 Dec 20;107(12):1852-8. Epub 2013 Sep 20.

Respiratory Research Unit, Bispebjerg University Hospital, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2013.09.007DOI Listing
December 2013

Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus.

Cochrane Database Syst Rev 2013 Nov 11(11):CD008143. Epub 2013 Nov 11.

Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 7812, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark, DK-2100.

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http://dx.doi.org/10.1002/14651858.CD008143.pub3DOI Listing
November 2013

Insulin resistance and impaired pancreatic β-cell function in adult offspring of women with diabetes in pregnancy.

J Clin Endocrinol Metab 2013 Sep 24;98(9):3793-801. Epub 2013 Jun 24.

Center for Pregnant Women with Diabetes, Department of Obstetrics, Research Unit 7821, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2013-1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763979PMC
September 2013