Publications by authors named "Alexandre Aalam"

5 Publications

  • Page 1 of 1

Use of platelet-rich fibrin in regenerative dentistry: a systematic review.

Clin Oral Investig 2017 Jul 27;21(6):1913-1927. Epub 2017 May 27.

Pain Clinic, Nice, France.

Objectives: Research across many fields of medicine now points towards the clinical advantages of combining regenerative procedures with platelet-rich fibrin (PRF). This systematic review aimed to gather the extensive number of articles published to date on PRF in the dental field to better understand the clinical procedures where PRF may be utilized to enhance tissue/bone formation.

Materials And Methods: Manuscripts were searched systematically until May 2016 and separated into the following categories: intrabony and furcation defect regeneration, extraction socket management, sinus lifting procedures, gingival recession treatment, and guided bone regeneration (GBR) including horizontal/vertical bone augmentation procedures. Only human randomized clinical trials were included for assessment.

Results: In total, 35 articles were selected and divided accordingly (kappa = 0.94). Overall, the use of PRF has been most investigated in periodontology for the treatment of periodontal intrabony defects and gingival recessions where the majority of studies have demonstrated favorable results in soft tissue management and repair. Little to no randomized clinical trials were found for extraction socket management although PRF has been shown to significantly decrease by tenfold dry sockets of third molars. Very little to no data was available directly investigating the effects of PRF on new bone formation in GBR, horizontal/vertical bone augmentation procedures, treatment of peri-implantitis, and sinus lifting procedures.

Conclusions: Much investigation now supports the use of PRF for periodontal and soft tissue repair. Despite this, there remains a lack of well-conducted studies demonstrating convincingly the role of PRF during hard tissue bone regeneration. Future human randomized clinical studies evaluating the use of PRF on bone formation thus remain necessary.

Clinical Relevance: PRF was shown to improve soft tissue generation and limit dimensional changes post-extraction, with little available data to date supporting its use in GBR.
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http://dx.doi.org/10.1007/s00784-017-2133-zDOI Listing
July 2017

Full mouth rehabilitation of a young patient with partial expressions of ectodermal dysplasia: a clinical report.

J Prosthet Dent 2014 Sep 19;112(3):449-54. Epub 2014 Jun 19.

Ralph and Jean Bleak Professor of Restorative Dentistry, Program Director, Advanced Prosthodontics, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, Calif.

Ectodermal dysplasia (ED) is a hereditary disorder characterized by the abnormal development of specific tissues and structures of ectodermal origin. This clinical report describes the multidisciplinary approach to the diagnosis and treatment of a 24-year-old patient with partial expression of ED. The treatment plan used dental implants to support fixed prostheses and ceramic restorations to establish acceptable esthetics and provide function.
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http://dx.doi.org/10.1016/j.prosdent.2014.01.028DOI Listing
September 2014

A multidisciplinary approach for the rehabilitation of a patient with an excessively worn dentition: a clinical report.

J Prosthet Dent 2014 Apr 14;111(4):259-63. Epub 2014 Feb 14.

Ralph and Jean Bleak Professor of Restorative Dentistry, Program Director, Advanced Prosthodontics, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, Calif.

This clinical report describes a multidisciplinary approach to the diagnosis and treatment of a patient with a severely worn dentition. The treatment included osteotomy and immediate implant placement and loading in the mandible. The definitive restorations were implant- and tooth-supported metal ceramic restorations. These restorations were fabricated with metal occlusal surfaces at an increased occlusal vertical dimension, which provided acceptable esthetics and function.
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http://dx.doi.org/10.1016/j.prosdent.2013.11.006DOI Listing
April 2014

Fabrication of the mandibular implant-supported fixed restoration using CAD/CAM technology: a clinical report.

J Prosthet Dent 2009 Nov;102(5):271-8

Division of Primary Oral Health Care, University of Southern California, School of Dentistry, Los Angeles, CA 90089-0641, USA.

The mandibular implant-supported fixed restoration is an appropriate treatment choice for patients with inadequate bone volume in the posterior mandible. Computer-aided design/computer-aided manufacturing (CAD/CAM) technology has broadened the scope and application for this treatment option. A milled titanium bar retaining individual all-ceramic zirconium oxide crowns, with composite resin replicating gingival tissues, is recommended as an acceptable variation for this type of prosthesis. An alternative method for fabricating a mandibular implant-supported fixed restoration using CAD/CAM technology is described.
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http://dx.doi.org/10.1016/S0022-3913(09)00123-1DOI Listing
November 2009

Periodontal antimicrobials--finding the right solutions.

Int Dent J 2005 Feb;55(1):3-12

University of Southern California, School of Dentistry, Los Angeles, CA 90089-0641, USA.

Strengthened by promising research data and commercial backing, interest in the field of anti-infective periodontal therapy is rapidly expanding. Management of the periodontal microbiota with antibiotic drugs and antiseptic agents in conjunction with mechanical debridement seems to be more effective than mechanical therapy alone, at least in the treatment of advanced periodontal disease. The choice of a periodontal chemotherapeutic regimen requires an understanding of the usual infecting flora, available antimicrobial agents, and pathogen susceptibility patterns. Systemic administration of combinations of metronidazole and either amoxicillin or ciprofloxacin has been widely used with great success; however the presence of subgingival yeasts and resistant bacteria can be a problem in some periodontitis patients. Valuable antiseptic agents for subgingival application include 10% povidone-iodine for professional use and 0.1-0.5% sodium hypochlorite for patient self-care. These antiseptics have significantly broader spectra of antimicrobial action, are less likely to induce development of resistant bacteria and adverse host reactions, and are considerably less expensive than commercially available antibiotics in controlled release devices. In practice, mechanical debridement combined with subgingival povidone-iodine application in the dental office and sodium hypochlorite irrigation for patient self-care are valuable antimicrobial remedies in the treatment of virtually all types of periodontal disease. Management of moderate to severe periodontitis may require additional systemic antibiotic and/or surgical treatment.
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http://dx.doi.org/10.1111/j.1875-595x.2005.tb00025.xDOI Listing
February 2005
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