Vet Microbiol 2020 Apr 20;243:108616. Epub 2020 Feb 20.
Programa De Pós-Graduação Em Farmacologia, Centro De Ciências Da Saúde, Departamento De Microbiologia e Parasitologia, Universidade Federal De Santa Maria (UFSM), Santa Maria, RS, Brazil; Departamento De Medicina Veterinária Preventiva, Centro De Ciências Rurais, UFSM, Santa Maria, RS, Brazil. Electronic address:
This study examined the effect of minocycline alone and in combination with immunotherapy against pythiosis. Twenty rabbits, aged three months old and subcutaneously inoculated with Pythium insidiosum zoospores were divided into four groups (n = 5): treated with minocycline (10 mg/kg/day twice daily), treated with immunotherapy (34 mg subcutaneously every 14 days), treated with minocycline plus immunotherapy, and untreated (control group). The treatments were started 30 days after inoculation and continued for 70 days. Read More