1,429,224 results match your criteria young

[Young Respiratory Physicians in Germany - Current Situation and Future Perspectives].

Pneumologie 2021 Apr 14. Epub 2021 Apr 14.

Charité - Universitätsmedizin Berlin, Mitglied der Freien Universität Berlin, Humboldt-Universität zu Berlin und des Berlin Institute of Health, Medizinische Klinik m. S. Infektiologie und Pneumologie, Berlin.

Background:  Demographic changes in the society and among doctors, as well as changing attitudes towards and norms of how living should be structured are creating challenges regarding the organization of work environment in the hospital. In addition, organization of medical training is increasingly being influenced by economic considerations as well as a high level of medical specialization. We asked young respiratory physicians how they assessed their current situation with respect to quality of medical training and organization of their work environment. Read More

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Transition Services for Paediatric Inflammatory Bowel Disease; A Multicentre Study of Practice in the United Kingdom.

J Pediatr Gastroenterol Nutr 2021 Apr 12. Epub 2021 Apr 12.

Department of Paediatric Gastroenterology, Southampton Children's Hospital, Southampton, UK Human Genetics and Genomic Medicine, University of Southampton, Southampton, UK Department of Paediatric Gastroenterology, Sheffield Children's NHS Foundation Trust, Sheffield, UK Department of Paediatric Gastroenterology, Great Ormond Street Hospital, London, UK Department of Paediatric Gastroenterology, Bristol Royal Hospital for Children, Bristol, UK Department of Paediatric Gastroenterology, The Royal Hospital for Sick Children, 9 Sciennes Rd, Edinburgh, UK Department of Paediatric Gastroenterology, Royal Hospital for Children Glasgow, 1345 Govan Road, Glasgow, UK Department of Paediatric Gastroenterology, Oxford University Hospitals, Oxford, UK Department of Paediatric Gastroenterology, Addenbrooke's Hospital, Cambridge, UK Department of Paediatric Gastroenterology, The Royal London Hospital, Barts Health NHS Trust, London, UK Department of Paediatric Gastroenterology, Alderhey Children's Hospital NHS Foundation Trust, West Derby, Eaton road, Liverpool L12 2AP,UK Department of Paediatric Gastroenterology, Birmingham Children's Hospital, Birmingham, UK Department of Paediatric Gastroenterology, St. Georges University Hospital NHS Foundation Trust, London, UK Department of Paediatric Gastroenterology, Chelsea and Westminster Hospital, 369 Fulham Road, London, UK Department of Paediatric Gastroenterology, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK Department of Paediatric Gastroenterology, University Hospitals of North Staffordshire NHS Trust, Stoke-On-Trent, UK Department of Paediatric Gastroenterology, Leeds Children's Hospital, Leeds Teaching Hospitals NHS trust, Leeds, UK Department of Paediatric Gastroenterology, Manchester Children's Hospital, Manchester, UK Department of Paediatric Gastroenterology, Nottingham Children's Hospital, Queens Medical Centre, Nottingham, UK Department of Paediatric Gastroenterology, University Hospitals of Leicester NHS Trust, Leicester, UK Department of Paediatric Gastroenterology, Evelina London Children's Hospital, UK.

Objectives: Patients with paediatric inflammatory bowel disease (IBD) constitute one of the largest cohorts requiring transition from paediatric to adult services. Standardised transition care improves short and long-term patient outcomes. This study aimed to detail the current state of transition services for IBD in the United Kingdom (UK). Read More

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Facial Skin Biophysical Profile of Women in Malaysia: Significance of Facial Skincare Product Use.

Skin Pharmacol Physiol 2021 Apr 14:1-12. Epub 2021 Apr 14.

Discipline of Pharmaceutical Technology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

Introduction: At present, there is a lack of baseline data on the facial skin biophysical profile of women in Malaysia. The implications related to the daily habits and facial skincare product use on the skin biophysical condition are, thus, unknown. In this study, we aim to evaluate facial skin biophysical parameters of Malaysian women and examine the influence of demographic characteristics, daily habits, and facial skincare product use on these parameters. Read More

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Track and Teach: Identifying Key Movement Patterns in Endoscopic Transurethral Enucleation of the Prostate.

Urol Int 2021 Apr 14:1-11. Epub 2021 Apr 14.

Department of Urology, Department of Surgery, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Purpose: We evaluated a system for noninvasive quantitative motion tracking to recognize differences in the movement pattern of experienced surgeons and beginners. Since performing endoscopic procedures requires extensive training, and tissue damage due to disruptive movements with sudden acceleration is possible, the learning curve for beginners is of clinical relevance. Steepening this curve may improve patient outcome. Read More

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Prevalence and Sociodemographic Determinants of Substance Use in Turkey.

Eur Addict Res 2021 Apr 14:1-10. Epub 2021 Apr 14.

Institute of Social Sciences/Feneryolu Health Center, Üsküdar University, Istanbul, Turkey.

Background: Substance use disorder is a serious public health problem. It is essential to know who is prone to substance use in order to adopt appropriate measures.

Objectives: This study aims to determine the use prevalence ratios of substance use (tobacco, alcohol, cannabis, cocaine, synthetic cannabinoids, ecstasy, and others) in a large-scale sample of a general population. Read More

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The role of radiation protection societies in tackling the skills shortage and development of young professionals and researchers.

J Radiol Prot 2021 Apr 14. Epub 2021 Apr 14.

Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Over the last 10 years there have been increasing concerns raised of a potential skills gap in field of radiation protection. Noting these concerns in 2019 the Society for Radiological Protection, the UK's Chartered Professional Body, launched a study to determine the radiation protection demand in the UK going forward along with the capacity of the profession. The initial results show that over 50% of the SRP membership retires in the next 10 -15 years, coupled with an increase in radiation protection demand across the nuclear fuel cycle, medical sector and advancement of new technologies or applications requiring radiation protection advice. Read More

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Gender Affirming Surgeries in Transgender and Gender Diverse Adolescent and Yong Adults: A Pediatric and Adolescent Gynecology Primer.

J Pediatr Adolesc Gynecol 2021 Apr 11. Epub 2021 Apr 11.

Center for Gender Surgery, Boston Children's Hospital, Boston, MA, USA; Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA, USA; Department of Surgery, Harvard Medical School, Boston, MA, USA.

Transgender and gender diverse adolescent and young adults (AYA) may seek gender affirming surgeries (GAS) as part of their gender affirmation. A number of GAS are related to reproductive and sexual health and pediatric and adolescent gynecology (PAG) clinicians are well positioned as sexual and reproductive health experts to provide care in this area. PAG clinicians may encounter patients presenting for preoperative counseling (including discussions regarding fertility, family building, future sexual function, and choice of oophorectomy at time of hysterectomy), requesting referrals to GAS clinicians, requiring GAS aftercare, or seeking general sexual and reproductive health care who have a history of GAS. Read More

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Outpatient antibiotic use attributable to viral acute lower respiratory tract infections during the cold season in France, 2010-2017.

Int J Antimicrob Agents 2021 Apr 11:106339. Epub 2021 Apr 11.

Epidemiology and Modeling of bacterial Evasion to Antibacterials Unit (EMEA), Institut Pasteur; 25 rue du docteur Roux, 75015, Paris, France; Université Paris-Saclay, UVSQ, Inserm, CESP; 16 Avenue Paul Vaillant Couturier, 94800 Villejuif, France. Electronic address:

Antibiotic stewardship requires clear insight into antibiotic overuse and into which syndromes lead to prescription. We aim to estimate the proportion of antibiotic prescriptions attributable to acute lower respiratory tract infections (LRTI) during the cold seasons. Using individual data from the French national health insurance, we constructed weekly time series of outpatient antibiotic (beta-lactams and macrolides) prescriptions between January 2010 and December 2017. Read More

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"Have We Done Enough?" A Cross-condition Exploration of the Experiences of Parents Caring for A Child with an Appearance-affecting Condition or Injury.

Dev Neurorehabil 2021 Apr 14:1-11. Epub 2021 Apr 14.

Centre for Appearance Research, Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK.

Children and young people (CYP) with appearance-affecting conditions/injuries report common pervasive psychosocial difficulties, regardless of cause, nature or extent of their visible differences. Parents or carers can also experience psychosocial difficulties and challenges specific to having CYP with a visible difference. Current literature is confined to exploring condition-specific concerns of parents, typically in more prevalent appearance-affecting conditions/injuries, whilst the experiences of parents of CYP with other visible differences are unknown. Read More

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Types of dental procedures provided to adults with autism spectrum condition: A descriptive study.

Spec Care Dentist 2021 Apr 14. Epub 2021 Apr 14.

The University of Iowa College of Dentistry and Dental Clinics, Iowa City, Iowa, USA.

Purpose/aim: To investigate demographic and systemic health characteristics, and the types of dental procedures performed for adults with autism that had sought care at a dental school.

Materials And Methods: De-identified data were collected from the records of patients aged 18+ who have self-reported autism. Each patient's age, gender, BMI, mental health, heart disease, xerostomia, tobacco use, alcohol use, diabetes, use of drugs, seizures, and total number of medications, as well as the type and number of dental codes used in the care of that patient within each code category were included as variables. Read More

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Pilot Randomized Clinical Trial of a Text Messaging-Based Intervention for Smoking Cessation Among Young People Experiencing Homelessness.

Nicotine Tob Res 2021 Apr 14. Epub 2021 Apr 14.

RAND Corporation; Santa Monica, CA.

Introduction: Smoking rates are alarmingly high among young people experiencing homelessness (YEH), yet there are no evidence-based cessation programs for this population. This paper presents results from a pilot evaluation of a text messaging-based smoking cessation treatment, as an adjunct to brief group cessation counseling, to improve abstinence rates among 18-25 year old smokers experiencing homelessness. The goal of this study was to estimate effect sizes for a larger trial and it was not powered to detect group differences. Read More

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Topical Imiquimod Does not Provide an Adjuvant Effect when Administered with Inactivated Influenza A/H5N1 Vaccine in Healthy Young Adults.

J Infect Dis 2021 Apr 14. Epub 2021 Apr 14.

Departments of Molecular Virology and Microbiology and Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

Background: Safe, effective and easy to deploy adjuvants are needed for influenza pre-pandemic preparedness. Based on recent reports we hypothesized that pre-application of topical imiquimod followed by intradermal (ID) vaccination with monovalent inactivated influenza A/H5N1 vaccine (MIV A/H5N1) results in improved serologic responses.

Methods: We randomized 50 healthy adults in a 1:1 ratio to receive topical imiquimod (Group 1) or control cream (Group 2) followed by ID injection of 9µg of the hemagglutinin (HA) MIV A/H5N1 in two doses, 21 days apart. Read More

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Factors associated with stress, anxiety, and depression during social distancing in Brazil.

Rev Saude Publica 2021 9;55. Epub 2021 Apr 9.

Universidade Católica de Pernambuco. Centro de Ciências Biológicas e da Saúde. Recife, Pernambuco, PE, Brasil.

Objective: To estimate the prevalence of clinical signs and symptoms of severe/extreme stress, anxiety, and depression, as well as their associated factors, among Brazilians during social distancing.

Methods: This is a cross-sectional study conducted in April/May 2020 with 3,200 Brazilians over 18 years old. Respondents' sociodemographic and clinical data were collected using an online questionnaire, which also included the 21-item Depression, Anxiety and Stress Scale (DASS-21) to assess emotional symptoms. Read More

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Recent HIV infection among pregnant women in the 2017 antenatal sentinel cross-sectional survey, South Africa: Assay-based incidence measurement.

PLoS One 2021 14;16(4):e0249953. Epub 2021 Apr 14.

Center for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa.

Introduction: New HIV infection during pre-conception and pregnancy is a significant contributor of mother-to-child transmission of HIV in South Africa. This study estimated HIV incidence (defined as new infection within the last one year from the time of the survey which included both new infections occurred during pregnancy or just before pregnancy) among pregnant women and described the characteristics of recently infected pregnant women at national level.

Methods: Between 1 October and 15 November 2017, we conducted a national cross-sectional survey among pregnant women aged 15-49 years old attending antenatal care at 1,595 public facilities. Read More

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Koala cathelicidin PhciCath5 has antimicrobial activity, including against Chlamydia pecorum.

PLoS One 2021 14;16(4):e0249658. Epub 2021 Apr 14.

School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.

Devastating fires in Australia over 2019-20 decimated native fauna and flora, including koalas. The resulting population bottleneck, combined with significant loss of habitat, increases the vulnerability of remaining koala populations to threats which include disease. Chlamydia is one disease which causes significant morbidity and mortality in koalas. Read More

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Ovarian Primitive Neuroectodermal Tumor: Are You Central or Peripheral?

Int J Gynecol Pathol 2021 Apr 12. Epub 2021 Apr 12.

Department of Pathology, Brigham & Women's Hospital, Boston, Massachusetts (S.E.B.) Departments of Obstetrics and Gynecology (L.A.B.) Pathology and Laboratory Medicine (J.C.D., D.W.P.), University of Kentucky, Lexington, Kentucky.

Primitive neuroectodermal tumors (PNETs) of the ovary are rare, highly aggressive neoplasms with fewer than 100 cases described. PNETs of the ovary can be classified as either peripheral or central types. The peripheral PNETs have small round cells with or without rosette formation, and the central PNETs can be further delineated based on the CNS tumor they morphologically resemble. Read More

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Selection of Mediastinal Lymphoma Patients for Proton Therapy Within the Proton Collaborative Group Registry: Concordance With the ILROG Guidelines.

Am J Clin Oncol 2021 Apr 13. Epub 2021 Apr 13.

Department of Radiation Oncology, University of Washington Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA Department of Radiation Oncology, University of Maryland School of Medicine and Maryland Proton Treatment Center, Baltimore, MD Oklahoma Proton Center, Oklahoma City, OK Procure Proton Therapy Center, Somerset, NJ Department of Radiation Oncology, Willis-Knighton Cancer Center, Shreveport, LA Northwestern Medicine Proton Center, Warrenville, IL Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ Department of Radiation Oncology, Scripps Health, San Diego, CA Department of Radiation Oncology, Emory Winship Cancer Institute, Atlanta, GA Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Radiation Oncology, Beaumont Health, Royal Oak, MI.

Purpose: As patients with mediastinal lymphoma are typically young with curable disease, advanced radiation techniques such as proton therapy are often considered to minimize subacute and late toxicity. However, it is unclear which mediastinal lymphoma patients are treated with proton therapy. Within a prospective, multi-institutional proton registry, we characterized mediastinal lymphoma patients treated with proton therapy and assessed concordance with consensus recommendations published in 2018 by the International Lymphoma Radiation Oncology Group (ILROG). Read More

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Hallux Sesamoid Injury Characteristics in Young Athletes Presented to the Sports Medicine Clinic.

Clin J Sport Med 2021 Mar 1. Epub 2021 Mar 1.

The Micheli Center for Sports Injury Prevention, Waltham, Massachusetts; Faculty of Sport Sciences,Waseda University, Tokyo, Japan; ARFID Program, Department of GI/Nutrition, Boston Children's Hospital, Boston, Massachusetts; Division of Sports Medicine, Department of Orthopaedics and Sports Medicine, Boston Children's Hospital, Boston, Massachusetts; and Harvard Medical School, Boston, Massachusetts.

Objective: To investigate clinical diagnoses, sports participation, and return to sport timeline associated with hallux sesamoid injuries with sex comparisons.

Design: Descriptive epidemiology study.

Setting: Sports medicine clinics at a tertiary-level pediatric medical center. Read More

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Additive effect of low skeletal muscle mass and abdominal obesity on coronary artery calcification.

Eur J Endocrinol 2021 Apr 1. Epub 2021 Apr 1.

J Kim, Medicine, Division of Endocrinology and Metabolism, Samsung Medical Center, Seoul, Korea (the Republic of).

Objective We aimed to investigate the interaction of reduced skeletal muscle mass and abdominal obesity on coronary artery calcification (CAC). Design and methods A total of 19,728 adults free of cardiovascular disease (CVD) who contemporaneously underwent cardiac tomography and bioelectrical impedance analysis were enrolled in a cross-sectional and longitudinal cohort. Skeletal muscle mass index (SMI) was calculated the following formula: SMI (%) = total appendicular muscle mass (kg)/body weight (kg) x 100 according to sex. Read More

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Bridging the digital divide with data-free platforms: Online survey reaching families with young children during the COVID-19 pandemic.

JMIR Pediatr Parent 2021 Apr 12. Epub 2021 Apr 12.

DSI-NRF Centre for Excellence in Human Development, University of the Witwatersrand, Office 154, First Floor, East Wing, Wits School of Public Health Education Campus27 St Andrews Road, Parktown, Johannesburg, ZA.

Background: The COVID-19 pandemic and containment measures have severely affected families around the world. It is frequently assumed that digital technologies can supplement and perhaps even replace services for families. This is challenging in conditions of high device and data costs as well as poor internet provision and access, raising concerns about widening inequalities in availability of support and consequent effects on child and family outcomes. Read More

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Disparities Between Provider Assessment and Documentation of Care Needs in the Care of Adolescent and Young Adult Patients With Sarcoma.

JCO Oncol Pract 2021 Apr 14:OP2000938. Epub 2021 Apr 14.

Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.

Purpose: Given the occurrence of cancer during a complex developmental time, adolescent and young adult (AYA) patients have unique psychosocial needs that necessitate supportive care, which is optimally provided using National Comprehensive Cancer Network (NCCN) AYA guidelines. We sought to explore compliance with NCCN AYA guidelines and compare with oncology providers' perceptions of AYA care needs.

Methods: Retrospective chart reviews of AYA patients (15-39 years at time of cancer diagnosis) with sarcoma seen at least once in 2019 at the University of Wisconsin identified documentation of discussions deemed critical per NCCN AYA guidelines. Read More

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Establishing Normal Testicular F-FDG PET/CT SUVs.

AJR Am J Roentgenol 2021 Apr 14:1-7. Epub 2021 Apr 14.

Department of Radiology, Mayo Clinic, 200 First St, Rochester, MN 55905.

Knowledge of normal testicular F-FDG PET/CT (FDG PET/CT) SUVs is crucial for accurate examination interpretation. The objective of this study was to establish normal testicular SUV ranges among adult men receiving health care in North America. A retrospective review of an institutional electronic database identified adult men undergoing pretreatment clinical FDG PET/CT examinations from March 15, 2013, through March 15, 2018. Read More

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Asynchronous Teledermatology Assessment of Young Adult Acne Likely Concordant With In-Person Evaluation.

J Drugs Dermatol 2021 Apr;20(4):432-435

Telemedicine, defined as practicing medicine at a distance, has grown in popularity over the past ten years, as advances in consumer technology have permitted its expansion. Dermatology is a field that especially lends itself to this method of care, as many common dermatological diagnoses can be made upon visual inspection. With social distancing becoming the new standard in this age of COVID-19, telemedicine emerges as a key tool in continuing patient care without interruption. Read More

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Frequency and characterization of mutations in genes in a large cohort of patients referred to MODY registry.

J Pediatr Endocrinol Metab 2021 Apr 12. Epub 2021 Apr 12.

Department of Pediatrics, Division of Molecular Genetics, Columbia University Medical Center, New York, NY,USA.

Objectives: There have been few large-scale studies utilizing exome sequencing for genetically undiagnosed maturity onset diabetes of the young (MODY), a monogenic form of diabetes that is under-recognized. We describe a cohort of 160 individuals with suspected monogenic diabetes who were genetically assessed for mutations in genes known to cause MODY.

Methods: We used a tiered testing approach focusing initially on and and then expanding to exome sequencing for those individuals without identified mutations in or . Read More

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C3 Glomerulopathy, a pathology with scarce evidence. A case report.

G Ital Nefrol 2021 Apr 14;38(2). Epub 2021 Apr 14.

MD, Internist, Nephrologist, Hospital Universitario de La Samaritana - Grupo de investigación UROHUS, Bogotá, Colombia.

C3 Glomerulonephritis (C3GN) is a rare disease with an estimated incidence of 1-2 cases per million, caused by an alteration in the alternative complement pathway, although its complete physiopathology remains uncertain. Treatment evidence is poor. Immunosuppressive therapy can be initiated in more severe cases. Read More

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Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans.

Diabetes Obes Metab 2021 Apr 14. Epub 2021 Apr 14.

Department of Internal Medicine, Clinic for Diabetes and Endocrinology, Viborg Regional Hospital, DK, Viborg, Denmark.

Context: Ketosis appears to decrease appetite and facilitate weight loss. Potential underlying mechanisms include decreases in plasma levels of the orexigenic hormone ghrelin and increases in appetite-inhibiting glucagon-like peptide-1 (GLP-1) levels. The effect of acute ketosis as compared to an isocaloric and isovolumetric beverage on both acyl ghrelin and total GLP-1 plasma concentrations has not been previously measured. Read More

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Parent and practitioner perspectives on Circle of Security Parenting (COS-P): A qualitative study.

Infant Ment Health J 2021 Apr 14. Epub 2021 Apr 14.

Centre for Emotional Health, Department of Psychology, Macquarie University, Sydney, New South Wales, Australia.

Circle of Security Parenting (COS-P) is an attachment-theory-informed program for parents of infants and young children. Designed for scalability, COS-P has been widely adopted internationally. Evidence for the program's effectiveness is limited, however, restricting capacity to make informed decisions about program allocation, and threatening ongoing program funding. Read More

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Treatment of Active Idiopathic Inflammatory Myopathies by Low-Dose Interleukin-2: A Prospective Cohort Pilot Study.

Rheumatol Ther 2021 Apr 14. Epub 2021 Apr 14.

Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, 100044, China.

Introduction: Treatment of idiopathic inflammatory myopathies (IIMs) is challenging due to a lack of safe and efficacious medication. Low-dose interleukin-2 (IL-2) treatment emerges as a new option in active IIMs. This study aims to explore the clinical and immunological effects of low-dose IL-2 in patients with active IIMs. Read More

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Diversity and functional structure of soil animal communities suggest soil animal food webs to be buffered against changes in forest land use.

Oecologia 2021 Apr 14. Epub 2021 Apr 14.

J.F. Blumenbach Institute of Zoology and Anthropology, University of Göttingen, Untere Karspüle 2, 37073, Göttingen, Germany.

Forest soil and litter is inhabited by a diverse community of animals, which directly and indirectly rely on dead organic matter as habitat and food resource. However, community composition may be driven by biotic or abiotic forces, and these vary with changes in habitat structure and resource supply associated with forest land use. To evaluate these changes, we compiled comprehensive data on the species composition of soil animal communities and environmental factors in forest types varying in land-use intensity in each of three regions in Germany, i. Read More

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Elution study of acrylic monomers from orthodontic materials using high performance liquid chromatography (HPLC).

J Orofac Orthop 2021 Apr 14. Epub 2021 Apr 14.

Institute of Dental, Oral and Maxillary Medicine, Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Aßmannshauser Str. 4-6, 14197, Berlin, Germany.

Purpose: Main goal of the study was the identification and quantitative analysis of monomer elution from materials commonly used in fixed orthodontic therapy. Studies have shown severe health effects of monomers including cytotoxic, allergenic or mutagenic potential and endocrine changes. This in vitro study focusses primarily on five resins which are usually processed intraorally and remain in the oral cavity long-term. Read More

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