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Survey on sodium and potassium intake in patients with hypertension in China.

J Clin Hypertens (Greenwich) 2021 Sep 25. Epub 2021 Sep 25.

Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Sodium and potassium intake in hypertensive patients in China is not clear. The authors aimed to investigate the distribution of sodium and potassium intake in hypertensive patients in China, and to analyze the relationship between sodium and potassium intake and blood pressure. The study was performed in 130 hospitals from 23 provinces across China from 2016 to 2019. Read More

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September 2021

Portuguese Version of COVID-19 Perceived Risk Scale and COVID-19 Phobia Scale: Psychometric Properties.

Eur J Investig Health Psychol Educ 2021 Sep 11;11(3):1044-1060. Epub 2021 Sep 11.

Research Center in Business and Economics (CICEE), Universidade Autónoma de Lisboa, Rua Sta. Marta 47, 5° Andar, 1150-293 Lisboa, Portugal.

The COVID-19 pandemic scenario has a psychological impact on individuals and society. A higher level of perceived risk concerning COVID-19 has been found when compared to other potential health threats. A misperception of risk in contrast with the real risk may lead people to develop disruptive cognitive, affective, or behavioral responses to the COVID-19 pandemic, namely, coronaphobia. Read More

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September 2021

Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma.

Clin Pract 2021 Sep 13;11(3):631-639. Epub 2021 Sep 13.

1-st Surgical Oncology Unit, Regional Institute of Oncology, General Henri Mathias Berthelot 2-4, 700483 Iasi, Romania.

Background: Epithelioid trophoblastic tumor (ETT) is a rare and newly defined disease, which most commonly occurs in women of reproductive age and can be a sequela of any gestational event. ETT can be present in both intrauterine and extrauterine sites.

Case Report: A woman of reproductive age, without specific comorbidities and with a single pregnancy and natural childbirth eight years ago, was diagnosed initially with poorly differentiated pleomorphic leiomyosarcoma on the hemostatic uterine curettage. Read More

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September 2021

Postoperative Neutrophil to Lymphocyte Ratio as an Overall Mortality Midterm Prognostic Factor following OPCAB Procedures.

Clin Pract 2021 Sep 3;11(3):587-597. Epub 2021 Sep 3.

Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-848 Poznan, Poland.

Background: Off-pump coronary artery bypass grafting (OPCAB) is believed to limit inflammatory reaction. Neutrophil to lymphocyte ratio (NLR) is one of the more common and easily accessible markers of inflammatory response. The aim of the study was to compare postoperative results of NLR with mid-term OPCAB results. Read More

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September 2021

The Use of Patient Reported Outcome Measures (PROMs) 6 Months Post-Stroke and Their Association with the National Institute of Health Stroke Scale (NIHSS) on Admission to Hospital.

Geriatrics (Basel) 2021 Sep 7;6(3). Epub 2021 Sep 7.

Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London WC2R 2LS, UK.

Patient Reported Outcome Measures (PROMs) assess clinical outcomes from the perspective of the patient. The stroke community recommended fifteen questions for use in stroke survivors, based on the established PROMIS10 with five additional stroke-specific questions. This study aimed to determine its association with the National Institute of Health Stroke Scale (NIHSS) on admission. Read More

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September 2021

Functional Status among Polymedicated Geriatric Inpatients at Discharge: A Population-Based Hospital Register Analysis.

Geriatrics (Basel) 2021 Sep 3;6(3). Epub 2021 Sep 3.

School of Health Sciences, HES-SO Valais/Wallis, 1950 Sion, Switzerland.

This study explored and compared the functional status of polymedicated and non-polymedicated geriatric inpatients at hospital discharge. We used a cross-sectional registry of geriatric patients' hospital records from a multi-site public hospital center in Switzerland. The analysis included all inpatients aged 65 years old or more admitted between 1 January 2015 and 31 December 2017 (n = 53,690), of whom 67. Read More

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September 2021

The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing.

Geriatrics (Basel) 2021 Aug 27;6(3). Epub 2021 Aug 27.

The Global Brain Health Institute (GBHI), Trinity College Dublin, D02 PN40 Dublin, Ireland.

The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations in health status within individuals of the same age. The aims of this study were to assess whether the addition of age to an FI improves its mortality prediction and whether the associations of the individual FI items differ in strength. Read More

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Skin Adverse Reactions to Novel Messenger RNA Coronavirus Vaccination: A Case Series.

Diseases 2021 Aug 27;9(3). Epub 2021 Aug 27.

Dermatology Clinic, Department Medical Sciences and Public Health, Cagliari State University, 09124 Cagliari, Italy.

Vaccines are actually the most effective strategy to control the COVID-19 spread and reduce mortality, but adverse reactions can occur. Skin involvement with novel messenger RNA coronavirus vaccines seems frequent but is not completely characterized. A real-world experience in the recent vaccination campaign among health care workers in Sardinia (Italy) is reported. Read More

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Triglyceride/Glucose Index (TyG Index) as a marker of glucose status conversion among reproductive-aged women in Jakarta, Indonesia: The Bogor cohort study (2011-2016).

Diabetes Metab Syndr 2021 Sep 11;15(6):102280. Epub 2021 Sep 11.

Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Background And Aims: Reproductive-aged women are prone to type 2 diabetes mellitus. This study aims to evaluate the optimal cut off point of Triglyceride/Glucose Index for predicting glucose status conversion among women of reproductive age.

Methods: This study involved normoglycemic and prediabetes women aged 20-49 years from the Bogor Non-Communicable Diseases Cohort Study (West Java, Indonesia) conducted from 2011 to 2016. Read More

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September 2021

Ultrasound feature variants of the adductor longus tendon in asymptomatic sportive subjects: Management implications.

Eur J Radiol 2021 Sep 20;144:109928. Epub 2021 Sep 20.

Centre d'imagerie ostéo-articulaire, clinique du sport de Bordeaux, 2, rue Georges-Negrevergne, 33700 Mérignac, France.

Objectives: The potential contribution of ultrasound (US) to diagnose adductor longus (AL) tendinopathy in athletic pubalgia requires clarification. We investigate US findings from AL tendons of asymptomatic participants to identify the range and prevalence of common US features not associated with groin pain.

Methods: We consecutively enrolled 45 volunteers physically active participants with no history of groin pain. Read More

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September 2021

Structural brain abnormalities in epilepsy with myoclonic atonic seizures.

Epilepsy Res 2021 Sep 21;177:106771. Epub 2021 Sep 21.

Pediatric Neurology and Neurorehabilitation Unit, Woman-Mother-Child Department, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland. Electronic address:

Objective: Epilepsy with myoclonic atonic seizure (EMAS) occurs in young children with previously normal to subnormal development. The outcome ranges from seizure freedom with preserved cognitive abilities to refractory epilepsy with intellectual disability (ID). Routine brain imaging typically shows no abnormalities. Read More

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September 2021

Diagnosis of Endometriosis at Laparoscopy: A Validation Study Comparing Surgeon Visualization with Histologic Findings.

J Obstet Gynaecol Can 2021 Sep 22. Epub 2021 Sep 22.

Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON, Canada, K1H 8L6; Department of Obstetrics, Gynecology and Newborn Care, University of Ottawa, Rm 7236-3, 1967 Riverside Drive, Ottawa, ON, Canada, K1H 7W9; Minimally Invasive Gynecology, The Ottawa Hospital, 501 Smyth Rd, Ottawa, ON, Canada, K1H 8L6.

Objective: This study aimed to evaluate the validity of laparoscopic visualization for the diagnosis of endometriosis compared with histopathology.

Methods: We conducted a retrospective chart review at a tertiary care hospital in Canada for the period of April 1, 2016 to March 31, 2017. Of 1069 women, 96 were selected for having undergone laparoscopic visualization and concurrent histopathological biopsy for suspected endometriosis. Read More

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September 2021

Serum Level of Polyubiquitinated PTEN and Loss of Kidney Function in American Indians With Type 2 Diabetes.

Am J Kidney Dis 2021 Sep 17. Epub 2021 Sep 17.

Senior Scientist, Chronic Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ.

Rationale & Objective: Fibrosis is a major driver of chronic kidney disease and epithelial-mesenchymal transition (EMT) may contribute to its development. A polyubiquitinated form of phosphatase and tensin homolog (PTEN ) promotes EMT in vitro. Thus, it is a potentially useful biomarker of progressive kidney fibrosis and may predict loss of kidney function. Read More

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September 2021

A descriptive qualitative case study of the experiences, perceptions, and attitudes of pregnant women on Unguja island, Zanzibar, towards antischistosomal treatment.

Acta Trop 2021 Sep 22:106143. Epub 2021 Sep 22.

Department of Life Sciences, Wolfson Wellcome Biomedical Laboratories, The Natural History Museum, London, United Kingdom. Electronic address:

Many countries exclude pregnant and lactating women from mass drug administration (MDA) programmes with praziquantel against schistosomiasis due to historic safety concerns over drug use during gestation and breast feeding. More than 10 years of empirical evidence from the field and a growing body of dedicated research has prompted the World Health Organisation and schistosomiasis control initiatives to advocate the inclusion of this vulnerable group into MDA. This qualitative descriptive case study explored, over a five-week period, the subjective experiences, perceptions, opinions, and attitudes of pregnant women attending government supported clinics on Unguja island, United Republic of Tanzania, towards praziquantel use during pregnancy in MDA programmes. Read More

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September 2021

Factors linked to accessing COVID-19 recommendations among working migrants.

Public Health Nurs 2021 Sep 25. Epub 2021 Sep 25.

Anglo-List, Haifa, Israel.

Objectives: Guided by the Health Belief Model (HBM), this study explored factors associated with accessing COVID-19 health information.

Design/sample: A cross-sectional study design was used.

Sample: Migrants (n = 259) employed in Israel prior to the onset of the COVID-19 pandemic were recruited. Read More

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September 2021

A multistate transition model for statin-induced myopathy and statin discontinuation.

CPT Pharmacometrics Syst Pharmacol 2021 Sep 25. Epub 2021 Sep 25.

Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.

The overarching goal of this study was to simultaneously model the dynamic relationships among statin exposure, statin discontinuation, and potentially statin-related myopathic outcomes. We extracted data from the Indiana Network of Patient Care for 134,815 patients who received statin therapy between January 4, 2004, and December 31, 2008. All individuals began statin treatment, some discontinued statin use, and some experienced myopathy and/or rhabdomyolysis while taking the drug or after discontinuation. Read More

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September 2021

Time dependency in early major osteoporotic and hip re-fractures in women and men aged 50 years and older: a population-based observational study.

Osteoporos Int 2021 Sep 25. Epub 2021 Sep 25.

McGill University, Montreal, Canada.

We analyzed patterns in recurrent major osteoporotic fracture (MOF) following a first major osteoporotic fracture in a large population-based cohort. Re-fracture risk remained elevated over 10 years, with only modest and inconsistent attenuation in risk over time.

Introduction: Recurrent fracture risk remains elevated for up to 25 years, and is reportedly highest in the initial 2 years (imminent risk). Read More

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September 2021

Right bundle branch block and risk of cardiovascular mortality: the Ibaraki Prefectural Health Study.

Heart Vessels 2021 Sep 25. Epub 2021 Sep 25.

Ibaraki Health Plaza, Ibaraki Health Service Association, Mito, Japan.

Historically, a right bundle branch block has been considered a benign finding in asymptomatic individuals. However, this conclusion is based on a few old studies with small sample sizes. We examined the association between a complete right bundle branch block (CRBBB) and subsequent cardiovascular mortality in the general population in Japan. Read More

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September 2021

Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease.

Graefes Arch Clin Exp Ophthalmol 2021 Sep 25. Epub 2021 Sep 25.

Department of Physics of Condensed Matter, Optics Area, Pharmacy Faculty, University of Seville, Reina Mercedes Street, 41012, Seville, Spain.

Purpose: To study the treatment efficacy of hyaluronic acid 0.3%, cyanocobalamin (vitamin B12), electrolytes, and P-Plus in menopausal patients with moderate dry eye disease.

Methods: Thirty female patients of mean age 53. Read More

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September 2021

Long-term diet quality and its change in relation to late-life subjective cognitive decline.

Am J Clin Nutr 2021 Sep 25. Epub 2021 Sep 25.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Background: Evidence regarding the role of diet quality, especially its change, in subjective cognitive decline (SCD) is scarce.

Objectives: To examine associations of long-term diet qualities, including Alternate Mediterranean Diet (AMED), Dietary Approaches to Stop Hypertension (DASH), and Alternate Healthy Eating Index 2010 (AHEI-2010) with SCD in the Nurses' Health Study.

Methods: We followed 49,493 female registered nurses averaged 48 years from 1984 to 2014. Read More

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September 2021

Independent effects of adiposity measures on risk of atrial fibrillation in men and women: a study of 0.5 million individuals.

Int J Epidemiol 2021 Sep 25. Epub 2021 Sep 25.

Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Background: Atrial fibrillation (AF) has a higher prevalence in men than in women and is associated with measures of adiposity and lean mass (LM). However, it remains uncertain whether the risks of AF associated with these measures vary by sex.

Methods: Among 477 904 UK Biobank participants aged 40-69 without prior AF, 23 134 incident AF cases were identified (14 400 men, 8734 women; median follow-up 11. Read More

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September 2021

Objectively measured patterns of daily physical activity and phenotypic frailty.

J Gerontol A Biol Sci Med Sci 2021 Sep 25. Epub 2021 Sep 25.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Background: Self-reported low physical activity is a defining feature of phenotypic frailty but does not adequately capture physical activity performed throughout the day. This study examined associations between accelerometer-derived patterns of routine daily physical activity and frailty.

Methods: Wrist accelerometer and frailty data from 638 participants (mean age 77 (SD=5. Read More

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September 2021

METTL3-Induced miR-222-3p Upregulation Inhibits STK4 and Promotes the Malignant Behaviors of Thyroid Carcinoma Cells.

J Clin Endocrinol Metab 2021 Sep 25. Epub 2021 Sep 25.

Department of Thyroid Surgery, The Sun Yat-Sen Memorial Hospital Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, P. R. China.

Context: Abnormally high expression of N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3) has been implied to accompany thyroid carcinoma (TC) development.

Objective: This study aimed to explore the protumorigenic role and downstream signaling axis of METTL3 in TC.

Methods: This study was conducted at the Sun Yat-Sen Memorial Hospital Sun Yat-Sen University. Read More

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September 2021

Prediction of vaginal birth after cesarean for labor dystocia by sonographic estimated fetal weight.

Int J Gynaecol Obstet 2021 Sep 24. Epub 2021 Sep 24.

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat-Gan, Israel.

Objective: To estimate the association of the weight difference between the index TOLAC sonographic estimated fetal weight (sEFW) and prior delivery birthweight with TOLAC success rate, among women with previous labor dystocia and no prior vaginal delivery.

Methods: A retrospective cohort study including all women with prior cesarean for labor dystocia and no prior vaginal delivery undergoing TOLAC during 3/2011-6/2020 with a sonographic estimated fetal weight within one week from delivery.

Results: Overall 168 women were included, of those 107 (63. Read More

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September 2021

Patients' preferences for quality-of-life aspects in sarcopenia: a best-worst scaling study.

Eur Geriatr Med 2021 Sep 25. Epub 2021 Sep 25.

Division of Public Health, Epidemiology and Health Economics, World Health Organization Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, University of Liège, Liège, Belgium.

Purpose: As information on patients' preferences regarding quality-of-life aspects in sarcopenia is lacking, this study aims to assess the relative importance of the 14 items of a QoL questionnaire designed for sarcopenia (the SF-SarQoL) using a best-worst scaling (BWS) survey.

Methods: Participants, aged 65 years or older and community dwelling, who previously participated in the SarcoPhAge study, received a BWS survey via the mail. An object case BWS was selected in which participants completed 12 choice tasks, picking the most and least important aspect from 4 out of 14 SF-SarQoL items for each task. Read More

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September 2021

Headache disability, lifestyle factors, health perception, and mental disorder symptoms: a cross-sectional analysis of the 2013 National Health Survey in Brazil.

Neurol Sci 2021 Sep 24. Epub 2021 Sep 24.

Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, School of Medicine, Universidade de São Paulo, São Paulo, Brazil.

Objective: To evaluate the past 2-week headache disability and explore its association with lifestyle factors, health perception, and mental disorder symptoms in the PNS 2013 survey.

Background: The prevalence of headache disorders has been associated with lifestyle factors, mental disorders, and health perception. However, less is known regarding their influence on headache-related disability. Read More

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September 2021

Intraoperative Indocyanine Green Angiography of Parathyroid Glands and the Prevention of Post-Thyroidectomy Hypocalcemia.

World J Surg 2021 Sep 24. Epub 2021 Sep 24.

Unidad de Cirugía Endocrina. Hospital Universitari de Bellvitge, Universidad de Barcelona (UB), C/ Feixa Llarga s/n, 08907, Barcelona, Spain.

Background: We compared the reliability of indocyanine green (ICG) angiography and intraoperative PTH levels for predicting early post-thyroidectomy hypocalcemia.

Methods: Prospective study of 94 patients (71% women, mean age 53.7 years) undergoing total thyroidectomy. Read More

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September 2021

Prevalence of high-grade dysplasia in cytology-negative, HPV-positive cervical cancer screening.

Arch Gynecol Obstet 2021 Sep 25. Epub 2021 Sep 25.

University of Wisconsin, Madison, WI, USA.

Purpose: This study has two aims: determine the prevalence of CIN3 + in patients with discordant cotesting, defined as negative cytology and positive human papillomavirus (HPV) testing, and identify factors (including HPV strain) associated with CIN3 + , defined as cervical intraepithelial neoplasia (CIN) 3 or cancer within this population.

Methods: We conducted a retrospective chart review of women age 30-65 with intact cervices who had discordant cotesting results between January 1, 2013 and September 1, 2018, at an academic medical center. We used the t test for continuous variables and the Chi-square test for categorical variables to compare women with and without CIN3 + . Read More

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September 2021