Epidemiology 2021 Dec 1. Epub 2021 Dec 1.
Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, KY, USA Danish Cancer Society Research Center, Copenhagen, Denmark Department of Environmental Science, Aarhus University, Roskilde, Denmark Center for Analytical Science, Research Triangle Institute, Research Triangle Park, NC, USA Department of Family Medicine, University of Colorado Denver, Denver, CO, USA Department of Public Health, Aarhus University, Aarhus, Denmark Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark Department of Public Health, University of Copenhagen, Copenhagen, Denmark Program in Public Health, Department of Family, Population, & Preventive Medicine, Stony Brook University, NY, USA Department of Environmental Health, Boston University, Boston, MA, USA.
Background: Epidemiologic studies suggest cadmium exposure is associated with cardiovascular disease risk, including heart failure. However, prior findings may be influenced by tobacco smoking, a dominant source of cadmium exposure and risk factor for heart failure. The present study leverages up to 20 years of follow-up in the Danish Diet, Cancer and Health cohort to examine the relationship between urinary cadmium and incident heart failure among people who never smoked. Read More