58,796 results match your criteria worldwide persons

Is a single COVID-19 vaccine dose enough in convalescents ?

Hum Vaccin Immunother 2021 May 5:1-3. Epub 2021 May 5.

Department of Medicine and Surgery, University of Insubria, Varese, Italy.

SARS-CoV-2 has infected more than 122 million persons worldwide. Most currently licensed COVID-19 vaccines require a two-dose course and many health systems are on a shortage of doses. The requirement for boosting the response after priming with the first dose is uncertain in convalescents already primed by the natural infection. Read More

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Potentially inappropriate proton-pump inhibitor prescription in the general population: a claims-based retrospective time trend analysis.

Therap Adv Gastroenterol 2021 15;14:1756284821998928. Epub 2021 Apr 15.

Institute of Primary Care, University of Zurich and University Hospital Zurich, Zurich, Switzerland.

Background: Proton-pump inhibitors (PPI) are among the most prescribed drugs worldwide, and a large body of evidence raises concerns about their inappropriate use. Previous estimates of inappropriate use varied due to different definitions and study populations.

Aims: We aimed to measure the population-based incidence and time trends of PPI and potentially inappropriate PPI prescriptions (PIPPI) with a novel method, continuously assessing excessive cumulative doses based on clinical practice guidelines. Read More

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Incidence of Guillain-Barré Syndrome in an Uruguayan population. A Prospective Cohort Study.

J Peripher Nerv Syst 2021 May 4. Epub 2021 May 4.

Department of Neurology, Clinical Professor of Neurology. Hospital de Clínicas, Montevideo, Uruguay.

Background And Aims: Guillain-Barre syndrome (GBS) is an acute autoimmune peripheral inflammatory neuropathy and the most frequent cause of non-poliovirus acute flaccid paralysis worldwide. Background annual GBS incidence rates (IRs) in Latin America (LA) varies from 0.40 to 2. Read More

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Epilepsy lifetime prevalence in Iran: a large population- based national survey.

Sci Rep 2021 May 3;11(1):9437. Epub 2021 May 3.

Shefa Neuroscience Research Center, Khatam-Ol-Anbia Hospital, Tehran, Iran.

Epilepsy has garnered increased public health focus because patients who suffer from epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment and care advances. The epidemiology of epilepsy is diverse in different countries and regions. This nationwide population-based cross-sectional study was conducted to determine the life time prevalence and health related factors of epilepsy for the first time in Iran through a two-phase door-to-door survey method. Read More

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Low rate of relapse after twelve-dose multidrug therapy for hansen's disease: A 20-year cohort study in a brazilian reference center.

PLoS Negl Trop Dis 2021 May 3;15(5):e0009382. Epub 2021 May 3.

Souza Araújo Outpatient Clinic, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.

The World Health Organization has raised concerns about the increasing number of Hansen disease (HD) relapses worldwide, especially in Brazil, India, and Indonesia that report the highest number of recurrent cases. Relapses are an indicator of MDT effectiveness and can reflect Mycobacterium leprae persistence or re-infection. Relapse is also a potential marker for the development or progression of disability. Read More

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Coupling hemodynamics with mechanobiology in patient-specific computational models of ascending thoracic aortic aneurysms.

Comput Methods Programs Biomed 2021 Apr 15;205:106107. Epub 2021 Apr 15.

Mines Saint-Étienne, Univ Lyon, Univ Jean Monnet, INSERM, U1059 Sainbiose, Saint-Étienne F - 42023 France. Electronic address:

Background And Objective: The prevention of ascending thoracic aortic aneurysms (ATAAs), which affect thousands of persons every year worldwide, remains a major issue. ATAAs may be caused by anything that weakens the aortic wall. Altered hemodynamics, which concerns a majority of patients with bicuspid aortic valves, has been shown to be related to such weakening and to contribute to ATAA development and progression. Read More

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Prospective pragmatic quasi-experimental study to assess the impact and effectiveness of an innovative large-scale public health intervention to foster healthy ageing in place: the SoBeezy program protocol.

BMJ Open 2021 Apr 29;11(4):e043082. Epub 2021 Apr 29.

University Hospital Centre Bordeaux Cardiology Hospital Anaesthesiology and Reanimation, Pessac, Nouvelle-Aquitaine, France.

Introduction: With the accelerating pace of ageing, healthy ageing has become a major challenge for all societies worldwide. Based on that Healthy Ageing concept proposed by the WHO, the SoBeezy intervention has been designed through an older person-centred and integrated approach. The programme creates the environments that maximise functional ability to enable people to be and do what they value and to stay at home in best possible conditions. Read More

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Med Clin North Am 2021 May 2;105(3):493-510. Epub 2021 Apr 2.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

Glaucoma is the leading cause of irreversible blindness worldwide. The global prevalence of glaucoma in people aged 40 to 80 years is estimated to be 3.5%. Read More

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COVID-2019 fundamentals.

J Am Dent Assoc 2021 05 5;152(5):354-363. Epub 2021 Feb 5.

Background: A novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified at the end of 2019. The disease caused by SARS-CoV-2 was named COVID-19. The main purpose of this review was to provide an overview of SARS-CoV-2. Read More

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Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital.

BMC Infect Dis 2021 Apr 29;21(1):397. Epub 2021 Apr 29.

Department of Nephrology, Division of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Road, Wuhan, 430030, Hubei, China.

Background: Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge.

Methods: Retrospective and prospective cohort study to patients with new-onset kidney disease during the COVID-19 hospitalization, admitted between January 28 to February 26, 2020. Read More

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Quality of Life and Symptoms of PTSD during the COVID-19 Lockdown in Italy.

Int J Environ Res Public Health 2021 04 20;18(8). Epub 2021 Apr 20.

Department of Development and Social Psychology, University of Padua, 35131 Padua, Italy.

The COVID-19 pandemic has led to a complete lockdown in many countries and Italy was the first country interested in Europe, as the cases spread very quickly with a high rate of mortality. While the lockdown strategy is an essential step to curb the exponential rise of COVID-19 cases, it can have a significative impact on mental health on the population involved, that is still not well known and must be explored. The objective of the present research is to investigate the Quality of Life (QoL) and Symptoms of PTSD (PTSS) encountered during the quarantine period (April 2020) due to the spread of COVID-19 in Italy. Read More

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CORONAcrisis-An Observational Study on the Experience of Healthcare Professionals in a University Hospital during a Pandemic Emergency.

Int J Environ Res Public Health 2021 04 16;18(8). Epub 2021 Apr 16.

Local Health Unit of Romagna, General Directorate, 48121 Ravenna, Italy.

The Coronavirus disease 2019 (COVID-19) pandemic continues to affect millions worldwide and has posed unique challenges to healthcare professionals. Caring for patients during a pandemic may have negative impacts on their mental health. We describe the first part of a study using a mixed-method sequential explanatory design (QUANT→QUAL). Read More

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Vaccination Prioritization Strategies for COVID-19 in Korea: A Mathematical Modeling Approach.

Int J Environ Res Public Health 2021 04 16;18(8). Epub 2021 Apr 16.

Department of Mathematical Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Korea.

Coronavirus disease 2019 (COVID-19) vaccination has recently started worldwide. As the vaccine supply will be limited for a considerable period of time in many countries, it is important to devise the effective vaccination strategies that reduce the number of deaths and incidence of infection. One of the characteristics of COVID-19 is that the symptom, severity, and mortality of the disease differ by age. Read More

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SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study.

Int J Environ Res Public Health 2021 04 25;18(9). Epub 2021 Apr 25.

Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 179, 45147 Essen, Germany.

SARS-CoV-2 is a worldwide challenge for the medical sector. Healthcare workers (HCW) are a cohort vulnerable to SARS-CoV-2 infection due to frequent and close contact with COVID-19 patients. However, they are also well trained and equipped with protective gear. Read More

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Effects of Home Confinement on the Intensity of Physical Activity during the COVID-19 Outbreak in Team Handball According to Country, Gender, Competition Level, and Playing Position: A Worldwide Study.

Int J Environ Res Public Health 2021 04 12;18(8). Epub 2021 Apr 12.

Department of Orthopaedic and Trauma Surgery, Martin-Luther-University Halle-Wittenberg, 06120 Halle, Germany.

This study investigated effects of home confinement on physical activity (PA) in Team Handball during the COVID-19 outbreak. A total of 1359 handball players participated (age: 23 ± 6 years). Participants from Europe, Western Asia, and North Africa answered an online version of the International Physical Activity Questionnaire (IPAQ) considering "before" and "during" confinement. Read More

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"If You Can't Control the Wind, Adjust Your Sail": Tips for Post-Pandemic Benefit Finding from Young Adults Living with Multiple Sclerosis. A Qualitative Study.

Int J Environ Res Public Health 2021 04 14;18(8). Epub 2021 Apr 14.

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, Italy.

The COVID-19 outbreak has impacted the wellbeing of people worldwide, potentially increasing maladaptive psychological responses of vulnerable populations. Although young adults with multiple sclerosis (yawMS) might be at greater risk of developing psychological distress linked to the pandemic, they might also be able to adapt to stress and find meaning in adverse life events. The aim of the present study was to explore benefit finding in response to the pandemic in a sample of yawMS. Read More

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Perspectives from Dentists, Dental Assistants, Students, and Patients on Dental Care Adapted to the COVID-19 Pandemic: A Cross-Sectional Survey.

Int J Environ Res Public Health 2021 04 9;18(8). Epub 2021 Apr 9.

Dental Clinic-Department of Pediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.

Dental care has been affected by SARS-CoV-2 (COVID-19) worldwide. In contrast to other dental clinics, the Justus-Liebig-University Giessen (Germany) decided not to limit dental treatment to emergencies alone, but to continue dental care for all patients, with increased safety measures. As such, health care professionals may be exposed to additional physical and mental stress. Read More

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COVID-19 Management in the Pediatric Age: Consensus Document of the COVID-19 Working Group in Paediatrics of the Emilia-Romagna Region (RE-CO-Ped), Italy.

Int J Environ Res Public Health 2021 04 8;18(8). Epub 2021 Apr 8.

Paediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.

Since December 2019, coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread, becoming the first pandemic of the 21st century by number of deaths (over 2,000,000 worldwide). Many aspects of SARS-CoV-2 infection in children and adolescents remain unclear, and optimal treatment has not yet been defined. Therefore, our goal was to develop a consensus document, practically synthesizing the accumulated data and clinical experience of our expert group. Read More

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SARS-CoV-2 Seroprevalence among Health Care Workers-A Voluntary Screening Study in a Regional Medical Center in Southern Germany.

Int J Environ Res Public Health 2021 04 8;18(8). Epub 2021 Apr 8.

Praxis Dr. J. Borde, Gesundheitszentrum Oberkirch, 77704 Oberkirch, Germany.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is associated with a potentially severe clinical manifestation, coronavirus disease 2019 (COVID-19), and currently poses a worldwide challenge. Health care workers (HCWs) are at the forefront of any health care system and thus especially at risk for SARS-CoV-2 infection due to their potentially frequent and close contact with patients suffering from COVID-19. Serum samples from 198 HCWs with direct patient contact of a regional medical center and several outpatient facilities were collected during the early phase of the pandemic (April 2020) and tested for SARS-CoV-2-specific antibodies. Read More

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Social Support and Optimism as Protective Factors for Mental Health among 7765 Healthcare Workers in Germany during the COVID-19 Pandemic: Results of the VOICE Study.

Int J Environ Res Public Health 2021 04 6;18(7). Epub 2021 Apr 6.

Department of Psychosomatic Medicine and Psychotherapy, University Hospital of Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.

Background: The COVID-19 pandemic is impacting mental health worldwide, particularly among healthcare workers (HCWs). Risk and protective factors for depression and generalized anxiety in healthcare workers need to be identified to protect their health and ability to work. Social support and optimism are known protective psychosocial resources, but have not been adequately studied in the context of the COVID-19 pandemic among healthcare workers in Germany. Read More

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SARS-CoV-2 Seroprevalence among Healthcare Workers in General Hospitals and Clinics in Japan.

Int J Environ Res Public Health 2021 04 5;18(7). Epub 2021 Apr 5.

SOUSEIKAI, 3-5-1 Kashiiteriha, Higashi-ku, Fukuoka 813-0017, Japan.

Coronavirus disease 2019 (COVID-19) has become a serious public health problem worldwide. In general, healthcare workers are considered to be at higher risk of COVID-19 infection. However, the prevalence of COVID-19 among healthcare workers in Japan is not well characterized. Read More

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[Lung ultrasound in patients with symptoms of covid-19].

Ned Tijdschr Geneeskd 2021 04 20;165. Epub 2021 Apr 20.

Radboudumc, afd. Interne Geneeskunde, Nijmegen.

The SARS-CoV-2 pandemic presents a challenge for healthcare worldwide. In this context, rapid, correct diagnosis and early isolation of infected persons is of great importance. Pneumonia as an expression of COVID-19 is responsible for the most part of morbidity and mortality. Read More

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Morbidity and mortality of parathyroid surgery - a retrospective analysis.

Rozhl Chir 2021 ;100(3):126-132

Introduction: The incidence of parathyroid - glandula parathyreoideae (PTG) diseases has been increasing worldwide. Unlike benign tumours, the incidence of malignant PTG tumours is rather a rare diagnosis. The morbidity of parathyroid surgery is associated with surgical removal of one or more pathologically altered parathyroid glands, particularly parathyroid adenoma associated with primary hyperparathyroidism (HPPT), but also hyperplasia associated with secondary or tertiary HPPT, and last but not least, HPPT due to parathyroid cancer. Read More

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Morbidity and mortality associated with thyroid surgery - retrospective analysis 19912010.

Rozhl Chir 2021 ;100(3):118-125

Introduction: The incidence of thyroid disorders has been rising worldwide. Unlike the incidence, mortality associated with malignant thyroid cancer shows only a modest increase. Between 1979 and 2009, mortality in Czech women increased from 1. Read More

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Arq Gastroenterol 2021 Jan-Mar;58(1):5-9

Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Background: Heartburn and acid regurgitation are typical symptoms usually associated with gastroesophageal reflux disease (GERD). GERD is one of the gastrointestinal diagnosis with higher prevalence worldwide, significantly impairing patients' quality of life.

Objective: The objective of this study was to analyze the impact of GERD-related symptoms in the Brazilian urban population. Read More

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Arq Gastroenterol 2021 Jan-Mar;58(1):26-31

Universidade Federal de São Paulo, Disciplina de Gastroenterologia, São Paulo, SP, Brasil.

Background: Worldwide, colorectal cancer (CRC) and gastric cancer (GC) are the third and the fifth most prevalent, respectively. Diarrhea is a common symptom in patients on chemotherapy or radiotherapy treatment and can reduce treatment tolerance. Surgical resections and chemotherapy change the intestinal microbiota that can lead to lactose intolerance, small intestinal bacterial overgrowth (SIBO). Read More

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[Pediatric inflammatory multisystem syndrome associated with COVID-19: A report of 10 cases in a Peruvian hospital].

Medwave 2021 Mar 30;21(2):e8142. Epub 2021 Mar 30.

Instituto de Investigación en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, Perú. ORCID: 0000-0002-1129-1427.

Pediatric inflammatory multisystem syndrome temporally associated with COVID-19 is a potentially severe and rare condition that still needs a better understanding to guide its management. Reports worldwide, and especially in Latin America, are still scarce. This report presents ten cases of pediatric inflammatory multisystem syndrome temporally associated with COVID-19 in children between 2 and 12 years old treated in a Peruvian hospital, diagnosed using the Centers for Disease Control and Prevention criteria. Read More

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Production of SARS-CoV-2 Antibodies and Emergence of the Clinical Symptoms of COVID-19.

Iran J Allergy Asthma Immunol 2021 Apr 17;20(2):244-248. Epub 2021 Apr 17.

Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran.

Coronavirus disease 2019 (COVID-19) is a worldwide public health problem that has attracted much attention due to its clinical findings. Measurement of IgG and IgM antibodies is of great importance for researchers and it will help to develop a new diagnostic and therapeutic method in clinical care. In this cross-sectional study, we aim to measure the IgG and IgM antibody levels in 401 suspected COVID-19 volunteers. Read More

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Clinical Presentation of Iranian Patients Affected with COVID-19: A Thousand Faces Disease.

Iran J Allergy Asthma Immunol 2021 Apr 17;20(2):140-146. Epub 2021 Apr 17.

Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.

The coronavirus disease 2019 (COVID-19) pandemic in Iran is part of the worldwide pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The present study aimed to demonstrate the clinical characteristics of patients affected by COVID-19, in our tertiary teaching hospital. Medical records and compiled data of 668 patients with suspected COVID-19 were obtained retrospectively between January to April 2020. Read More

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