89,645 results match your criteria working mechanism


2D/3D S-scheme heterojunction of carbon nitride/iodine-deficient bismuth oxyiodide for photocatalytic hydrogen production and bisphenol A degradation.

J Colloid Interface Sci 2022 Jan 6;612:722-736. Epub 2022 Jan 6.

School of Materials Engineering, Changshu Institute of Technology, Changshu, China; Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China. Electronic address:

A novel 2D/3D S-scheme carbon nitride/iodine-deficient bismuth oxyiodide (g-CN/BiOI) heterojunction was constructed for the first time by calcining a mixture of g-CN nanosheets and flower-like BiOI. Irradiated by visible light, this g-CN/BiOI heterojunction exhibited excellent photocatalytic hydrogen production and BPA degradation activity with high cycle stability. In particular, the photocatalytic activity of 0. Read More

View Article and Full-Text PDF
January 2022

Treatment of oily wastewaters by highly porous whisker-constructed ceramic membranes: Separation performance and fouling models.

Water Res 2022 Jan 6;211:118042. Epub 2022 Jan 6.

Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education, MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China. Electronic address:

Efficient treatment of challenging oily emulsion wastewater can alleviate water pollution to provide more chances for water reuse and resource recovery. Despite their promising application potential, conventional porous ceramic membranes have challenging bottleneck issues such as high cost and insufficient permeance. This study presents a new strategy for highly efficient treatment of not only synthetic but real oily emulsions via unexpensive whisker-constructed ceramic membranes, exhibiting exceptional permeance and less energy input. Read More

View Article and Full-Text PDF
January 2022

Determination of elemental bioavailability in soils and sediments by microwave induced plasma optical emission spectrometry (MIP-OES): Matrix effects and calibration strategies.

Talanta 2021 Dec 28;240:123166. Epub 2021 Dec 28.

Department of Chemistry, University of Girona, 17071, Girona, Spain.

In the past few years, microwave induced plasma optical emission spectrometry (MIP-OES) has generated great interest as an alternative technique to inductively coupled plasma-based techniques due to its lower operational cost. Since MIP-OES suffers from severe matrix effects due to easily ionizable elements (EIEs) (Na, Ca, etc.), it is unclear whether this technique could be employed for elemental bioavailability studies in soils and sediments since the main extractant solutions employed in such works may contain high levels of these elements. Read More

View Article and Full-Text PDF
December 2021

Optimal design of a multi-dimensional validated synergistic extraction process for the treatment of atmosphere-vacuum distillation wastewater.

Sci Total Environ 2022 Jan 12;817:152986. Epub 2022 Jan 12.

College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.

The wastewater discharged from atmosphere-vacuum distillation of oil refining process contains a high concentration of phenolic compounds, which are toxic and not eco-friendly. Direct discharge of the untreated wastewater will have an adverse impact on the surrounding environment. This paper proposes a multi-dimensional synergistic extraction solution to realize the effective disposal of atmosphere-vacuum distillation wastewater. Read More

View Article and Full-Text PDF
January 2022

Pomegranate-like structured NbO/[email protected] carbon composites as ultrastable anode for advanced sodium/potassium-ion batteries.

J Colloid Interface Sci 2022 Jan 7;613:84-93. Epub 2022 Jan 7.

School of Physics and Electronics, Gannan Normal University, Ganzhou 341000, PR China.

The distinctive pomegranate-like NbO/[email protected] carbon (NbO/[email protected]) composites are fabricated using hydrothermal method integrated with nitrogen doped carbon coating procedure. For the SIBs anode, the NbO/[email protected] composites present superior rate character and sustainable capacity (117 mAh g upon 1000 cycles at 5 A g). The in-situ X-ray diffraction (XRD) is utilized to research its sodium storage mechanism. Read More

View Article and Full-Text PDF
January 2022

Efficient pollutant degradation under ultraviolet to near-infrared light irradiation and dark condition using CuSe nanosheets: Mechanistic insight into degradation.

J Colloid Interface Sci 2022 Jan 7;613:103-116. Epub 2022 Jan 7.

College of Life and Environmental Science, Minzu University of China, Beijing 100081, PR China; School of Science, Minzu University of China, Beijing 100081, PR China. Electronic address:

The hydrothermally prepared two-dimensional copper selenide nanosheets (2D CuSe NSs) have been employed for the first time to degrade rhodamine B (RhB) in the presence of hydrogen peroxide (HO) under ultraviolet to near-infrared (NIR) light irradiation and dark condition. The experimental measurements demonstrate that 99.7% RhB is degraded under NIR light irradiation for 120 min. Read More

View Article and Full-Text PDF
January 2022

Study on the interaction between 2,6-dihydroxybenzoic acid nicotine salt and human serum albumin by multi-spectroscopy and molecular dynamics simulation.

Spectrochim Acta A Mol Biomol Spectrosc 2022 Jan 10;270:120868. Epub 2022 Jan 10.

School of Chemical Engineering, Sichuan University, Chengdu, Sichuan 610065, China.

As a new form of nicotine introduction for novel tobacco products, the interaction of nicotine salt with biological macromolecules may differ from that of free nicotine and thus affect its transport and distribution in vivo. Hence, the mechanism underlying the interaction between 2,6-dihydroxybenzoic acid nicotine salt (DBN) and human serum albumin (HSA) was investigated by multi-spectroscopy, molecular docking, and dynamic simulation. Experiments on steady-state fluorescence and fluorescence lifetime revealed that the quenching mechanism of DBN and HSA was dynamic quenching, and binding constant was in the order of 10^4 L mol. Read More

View Article and Full-Text PDF
January 2022

Lycopene attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/NF-κB balance in sulfamethoxazole-induced neurotoxicity in grass carp (Ctenopharyngodon Idella).

Fish Shellfish Immunol 2022 Jan 12. Epub 2022 Jan 12.

College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, Heilongjiang, PR China. Electronic address:

All drugs that can penetrate the blood-brain barrier (BBB) may lead to mental state changes, including the widely used anti-infective drug sulfamethoxazole (SMZ). Herein, we investigated whether lycopene (LYC) could ameliorate SMZ-induced brain injury and the postulated mechanisms involved. A total of 120 grass carps were exposed under SMZ (0. Read More

View Article and Full-Text PDF
January 2022

Transcriptomic analysis of salivary gland and proteomic analysis of oral secretion in Helicoverpa armigera under cotton plant leaves, gossypol, and tannin stresses.

Genomics 2022 Jan 12. Epub 2022 Jan 12.

State Key Laboratory of Cotton Biology/Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang 455000, Henan, China. Electronic address:

Gossypol and tannin are involved in important chemical defense processes in cotton plants. In this study, we used transcriptomics and proteomics to explore the changes in salivary gland functional genes and oral secretion (OS) proteins after feeding with artificial diet (containing gossypols and tannins) and cotton plant leaves. We found that dietary cotton plant leaves, gossypols and tannins exerted adverse impacts on the genes that regulated the functions of peptidase, GTPase, glycosyl hydrolases in the salivary glands of the Helicoverpa armigera (H. Read More

View Article and Full-Text PDF
January 2022

Degradation of toxic agrochemicals and pharmaceutical pollutants: Effective and alternative approaches toward photocatalysis.

Environ Pollut 2022 Jan 12:118844. Epub 2022 Jan 12.

Department of Biotechnology, Rajalakshmi Engineering College, Chennai, 602105, India.

Emerging concern regarding the remediation of environmental pollution has expanded tremendously in recent years. Pharmaceutical industries and agricultural sectors release an enormous amount of residues containing toxic pollutants at trace levels which poses a serious impact on the environment and human health. To cope with the effect of hazardous and toxic contaminants, numerous methodologies have been developed for the treatment of effluents released from the agrochemical and pharmaceutical industries. Read More

View Article and Full-Text PDF
January 2022

Combination of molecular docking and liver transcription sequencing analysis for the evaluation of salt-processed psoraleae fructus-induced hepatotoxicity in ovariectomized mice.

J Ethnopharmacol 2022 Jan 12:114955. Epub 2022 Jan 12.

Jiangsu Key Laboratory of Chinese Medicine Processing, Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. Electronic address:

Ethnopharmacological Relevance: Salt-processed Psoraleae fructus (SPF) is widely used as a phytoestrogen-like agent in the treatment of osteoporosis. However, SPF-associated hepatotoxicity is a known health hazard. Cholestasis is often associated with SPF-induced hepatotoxicity. Read More

View Article and Full-Text PDF
January 2022

Hypoglycemic and hypolipidemic effects of Epigynum auritum in high fat diet and streptozotocin-induced diabetic rats.

J Ethnopharmacol 2022 Jan 12:114986. Epub 2022 Jan 12.

Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, 650500, People's Republic of China. Electronic address:

Ethnopharmacological Relevance: Epigynum auritum is mainly distributed in Southwest China, and has been used as a "dai" folk medicine with promising Besides, the leaves and barks of E. auritum have detoxifying, analgesic and relieving swelling effects. Previous studies evidenced that E. Read More

View Article and Full-Text PDF
January 2022

In vitro anti-Helicobacter pylori activity of Syzygium aromaticum and the preliminary mechanism of action.

J Ethnopharmacol 2022 Jan 12:114995. Epub 2022 Jan 12.

School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China. Electronic address:

Ethnopharmacological Relevance: The dried flower bud of Syzygium aromaticum (L.) Merr. & L. Read More

View Article and Full-Text PDF
January 2022

DEHP-induced mitophagy and mitochondrial damage in the heart are associated with dysregulated mitochondrial biogenesis.

Food Chem Toxicol 2022 Jan 12:112818. Epub 2022 Jan 12.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, PR China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, Northeast Agricultural University, Harbin, 150030, PR China; Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Northeast Agricultural University, Harbin, 150030, PR China. Electronic address:

Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer widely used in agricultural and industrial plastic products. Many researchers have demonstrated that DEHP can cause varying degrees of harm to the heart. This research investigated the mechanism by which DEHP causes heart damage in quail. Read More

View Article and Full-Text PDF
January 2022

Use of activated carbon to reduce ammonia emissions and accelerate humification in composting digestate from food waste.

Bioresour Technol 2022 Jan 12:126701. Epub 2022 Jan 12.

Shenzhen Engineering Laboratory for Eco-efficient Recycled Materials, School of Environment and Energy, Peking University Shenzhen Graduate School, University Town, Xili, Nanshan District, Shenzhen 518055, China. Electronic address:

Management of digestate from food waste (DFW) is becoming the bottleneck of the food waste anaerobic digestion. Composting is a feasible method to dispose the DFW and convert it to organic fertilizer; however, high ammonia (NH) emissions and long composting time are key concerns in this process. In this study, the mechanism of activated carbon (AC) on the loss of NH and humification during DFW composting was investigated. Read More

View Article and Full-Text PDF
January 2022

Simultaneous recovery of vivianite and produce short-chain fatty acids from waste activated sludge using potassium ferrate as pre-oxidation treatment.

Environ Res 2022 Jan 12:112661. Epub 2022 Jan 12.

State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin, 150090, China; School of Civil Engineering, Lanzhou University of Technology, Lanzhou, 730070, PR China. Electronic address:

Recovery resources from waste active sludge (WAS) is an effective way to alleviate the predicament of WAS disposal, and it is also conducive to the carbon neutralization of wastewater treatment systems. This study discussed the strategy of WAS anaerobic fermentation after pre-oxidation with potassium ferrate (KFeO, PF), which can simultaneously recover vivianite and enhance SCFAs production. The results showed that PF pre-oxidation considerably shortened the fermentation time of SCFAs to 2 days, and the main Fe-P mineral was vivianite. Read More

View Article and Full-Text PDF
January 2022

Cerebral Blood Flow Self-regulation in Depression.

J Affect Disord 2022 Jan 12. Epub 2022 Jan 12.

Department of Neurology, The First Hospital of Jilin University, Changchun, China. Electronic address:

Background: Depression is a common neuropsychiatric disease with a high prevalence rate. Sleep problems, memory decline, dizziness and headaches are the most common neurological symptoms in depressed patients. Abnormality of cerebral blood flow (CBF) has been observed in depressive patients, but those patients did not have intracranial structural damage. Read More

View Article and Full-Text PDF
January 2022

Alhagi honey polysaccharides encapsulated into PLGA nanoparticle-based pickering emulsion as a novel adjuvant to induce strong and long-lasting immune responses.

Int J Biol Macromol 2022 Jan 12. Epub 2022 Jan 12.

College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

Alhagi honey polysaccharides, extracted from a perennial plant Alhagi pseudalhagi syn, possessed many biological activities such as immune enhancement, anti-tumor effect, and antioxygenation. In this study, we used Alhagi honey polysaccharide encapsulated (poly lactic-co-glycolic acid) (PLGA) nanoparticles to prepare an assembled particles-oil pickering emulsion: PPAS and PEI-PPAS. We investigated the characterization of two pickering emulsions, and the possible mechanism to enhance immune responses. Read More

View Article and Full-Text PDF
January 2022

Proteomic profiling reveals antitumor effects of RT2 peptide on a human colon carcinoma xenograft mouse model.

Eur J Pharmacol 2022 Jan 12:174753. Epub 2022 Jan 12.

Protein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand; Department of Integrated Science, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand. Electronic address:

A comparative study of human colon HCT-116 xenograft in nude mice treated with and without peptide RT2 at high doses is performed along with a label-free proteomic analysis of the tissue in order to understand the potential mechanisms by which RT2 acts in vivo against colorectal tumors. RT2 displays no significant systematic toxicity, but reduces tumor growth after either intraperitoneal or intratumoral injection demonstrating it is a safe and efficacious antitumor agent in vivo. Of the 3196 proteins identified by label-free proteomics, 61 proteins appear only in response to RT2 and are involved in cellular processes largely localized in the cells and cell parts. Read More

View Article and Full-Text PDF
January 2022

Role of systems biology and multi-omics analyses in delineating spatial interconnectivity and temporal dynamicity of ER stress mediated cellular responses.

Biochim Biophys Acta Mol Cell Res 2022 Jan 12:119210. Epub 2022 Jan 12.

Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, IICB TRUE Campus, CN-6, Sector 5, Salt Lake, Kolkata Pin 700091, WB, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India. Electronic address:

The endoplasmic reticulum (ER) is a membranous organelle involved in calcium storage, lipid biosynthesis, protein folding and processing. Many patho-physiological conditions and pharmacological agents are known to perturb normal ER function and can lead to ER stress, which severely compromise protein folding mechanism and hence poses high risk of proteotoxicity. Upon sensing ER stress, the different stress signaling pathways interconnect with each other and work together to preserve cellular homeostasis. Read More

View Article and Full-Text PDF
January 2022

Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle.

FASEB J 2022 Feb;36(2):e22133

Laboratory Genetic Metabolic Diseases, Amsterdam Gastroenterology, Endocrinology, and Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Shift-workers show an increased incidence of type 2 diabetes mellitus (T2DM). A possible mechanism is the disruption of the circadian timing of glucose homeostasis. Skeletal muscle mitochondrial function is modulated by the molecular clock. Read More

View Article and Full-Text PDF
February 2022

The Time Moving exhibit: Exploring perceptions of time in end-of-life experiences.

Health Expect 2022 Jan 15. Epub 2022 Jan 15.

Health Design Studio, OCAD University, Toronto, Ontario, Canada.

Background: Conversations about end of life rarely take place beyond healthcare spaces and in advance of imminent death. As the Canadian ageing population increases and new policies and options emerge for end-of-life choices, there will be an increasing need for supports for decision-making on end of life. Time Moving was a participatory art exhibit created to engage participants in reflections on end-of-life experiences and the ways in which their perception of time fluctuated within these moments. Read More

View Article and Full-Text PDF
January 2022

An integrated in silico analysis highlighted angiogenesis regulating miRNA-mRNA network in PCOS pathophysiology.

J Assist Reprod Genet 2022 Jan 15. Epub 2022 Jan 15.

Department of Molecular Endocrinology, Indian Council of Medical Research-National Institute for Research in Reproductive Health, J.M. Street, Parel, Mumbai, 400012, India.

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrinopathy and a leading cause of anovulatory infertility. Angiogenesis is vital for ovarian folliculogenesis. The expression of angiogenesis-associated genes/proteins is altered in the ovary of PCOS women. Read More

View Article and Full-Text PDF
January 2022

Designing Conductive-Bridge Phase-Change Memory to Enable Ultralow Programming Power.

Adv Sci (Weinh) 2022 Jan 14:e2103478. Epub 2022 Jan 14.

Center for Alloy Innovation and Design (CAID), State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, Xi'an, 710049, China.

Phase-change material (PCM) devices are one of the most mature nonvolatile memories. However, their high power consumption remains a bottleneck problem limiting the data storage density. One may drastically reduce the programming power by patterning the PCM volume down to nanometer scale, but that route incurs a stiff penalty from the tremendous cost associated with the complex nanofabrication protocols required. Read More

View Article and Full-Text PDF
January 2022

Tunable Assembly of Organic-Inorganic Molecules into Hierarchical Superstructures as Ligase Mimics for Enhancing Tumor Photothermal Therapy.

Small 2022 Jan 14:e2105304. Epub 2022 Jan 14.

MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Beijing Key Lab of Microanalytical Methods & Instrumentation, Department of Chemistry, Center for Synthetic and Systems Biology, Tsinghua University, Beijing, 100084, P. R. China.

The assembly of molecules into hierarchical superstructures is ubiquitous in the construction of novel geometrically complex hierarchical superstructures, attracting great attention. Herein, a metal-ligand cross-linking strategy is developed for the fabrication of ferric ion-dopamine coordination hierarchical superstructures. A range of superstructures with highly complex morphologies, such as flower-like, octopus-like, and hedgehog-like superstructures, are synthesized. Read More

View Article and Full-Text PDF
January 2022

Pathogen resistance in Sphagneticola trilobata (Singapore daisy): molecular associations and differentially expressed genes in response to disease from a widespread fungus.

Genetica 2022 Jan 15. Epub 2022 Jan 15.

School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, People's Republic of China.

Understanding the molecular associations underlying pathogen resistance in invasive plant species is likely to provide useful insights into the effective control of alien plants, thereby facilitating the conservation of native biodiversity. In the current study, we investigated pathogen resistance in an invasive clonal plant, Sphagneticola trilobata, at the molecular level. Sphagneticola trilobata (i. Read More

View Article and Full-Text PDF
January 2022

Temperature and interlayer coupling induced thermal transport across graphene/2D-SiC van der Waals heterostructure.

Sci Rep 2022 Jan 14;12(1):761. Epub 2022 Jan 14.

Department of Electrical and Biomedical Engineering, University of Nevada, Reno, NV, 89557, USA.

Graphene based two-dimensional (2D) van der Waals (vdW) materials have attracted enormous attention because of their extraordinary physical properties. In this study, we explore the temperature and interlayer coupling induced thermal transport across the graphene/2D-SiC vdW interface using non-equilibrium molecular dynamics and transient pump probe methods. We find that the in-plane thermal conductivity κ deviates slightly from the 1/T law at high temperatures. Read More

View Article and Full-Text PDF
January 2022

Calcium Selective Channel TRPV6: Structure, Function, and Implications in Health and Disease.

Gene 2022 Jan 11:146192. Epub 2022 Jan 11.

Division of Nephrology, Department of Medicine, Nephrology Research and Training Center, Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in transcellular calcium (Ca) transport, reuptake of Ca into cells, and maintaining a local low Ca environment for certain biological processes. Recent crystal and cryo-electron microscopy-based structures of TRPV6 have revealed mechanistic insights on how the protein achieves Ca selectivity, permeation, and inactivation by calmodulin. The TRPV6 protein is expressed in a range of epithelial tissues such as the intestine, kidney, placenta, epididymis, and exocrine glands such as the pancreas, prostate and salivary, sweat, and mammary glands. Read More

View Article and Full-Text PDF
January 2022

KEPI Plays a Negative Role in the Repression that Accompanies Translational Inhibition Guided by the uORF Element of Human chop Transcript during Stress Response.

Gene 2022 Jan 11:146160. Epub 2022 Jan 11.

Institute of Biomedical Sciences, Mackay Medical College, New Taipei City, Taiwan; Institute of Molecular and Cellular Biology, National Taiwan University, Taipei, Taiwan; Department of Life Science, Fu-Jen Catholic University, New Taipei City, Taiwan. Electronic address:

Translation of the downstream coding sequence of some mRNAs may be repressed by the upstream open reading frame (uORF) at their 5'-end. The mechanism underlying this uORF-mediated translational inhibition (uORF-MTI) is not fully understood in vivo. Recently, it was found that zebrafish Endouc or its human orthologue ENDOU (Endouc/ENDOU) plays a positive role in repressing the uORF-MTI of human chop (uORF-MTI) during stress by blocking its activity However, the repression of uORF-MTI assisted by an as-yet unidentified negative effector remains to be elucidated. Read More

View Article and Full-Text PDF
January 2022

Comparative transcriptome analysis reveals distinct responsive biological processes in radish genotypes contrasting for Plasmodiophora brassicae interaction.

Gene 2022 Jan 11:146170. Epub 2022 Jan 11.

Horticultural Research Institute, d, Kunming 650205, China. Electronic address:

Plasmodiophora brassicae is a protozoan pathogen that causes clubroot disease, which is one of the most destructive diseases for Brassica crops, including radish. However, little is known about the molecular mechanism of clubroot resistance in radish. In this study, we performed a comparative transcriptome analysis between resistant and susceptible radish inoculated with P. Read More

View Article and Full-Text PDF
January 2022