18,503 results match your criteria women congenital


Perceptions of Health Care, Information, and Social Support Among Women Affected by Zika Virus Infection During Pregnancy in Two U.S. States.

Matern Child Health J 2021 Oct 20. Epub 2021 Oct 20.

Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Objectives: To understand the information needs and experiences with health care and social support among women with confirmed or possible Zika virus infection during pregnancy.

Methods: We conducted in-depth interviews with 18 women whose pregnancies were part of surveillance efforts in two states, Pennsylvania and Virginia. Using a semi-structured guide available in English and Spanish, we asked women about their experiences. Read More

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October 2021

Epidemiology of cytomegalovirus infection in pregnancy in Israel: real-world data from a large healthcare organization.

J Med Virol 2021 Oct 19. Epub 2021 Oct 19.

Merck & Co., Inc., Kenilworth, NJ, USA.

Objectives: Congenital cytomegalovirus infection (cCMVi) is the leading cause of nonhereditary sensorineural hearing loss among newborns. Women newly acquiring cytomegalovirus infection (CMVi) during pregnancy have the highest risk of vertical transmission. This study aimed to describe the epidemiology of CMVi in pregnancy in a large healthcare database. Read More

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October 2021

Association between adverse pregnancy outcomes and preceding risk factors: a cross-sectional study from Nashik District, India.

BMC Pregnancy Childbirth 2021 Oct 18;21(1):700. Epub 2021 Oct 18.

UNICEF Maharashtra, Mumbai, India.

Background: The preconception phase of women's life cycle is critical but comparatively ignored. The presence of health risks is judged as hazardous to the wellbeing of women and their offspring. This study aimed to estimate the prevalence of various pregnancy outcomes and assess the association between certain risk factors and adverse outcomes. Read More

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October 2021

Association Between Maternal Race and the Occurrence of Cyanotic Congenital Heart Disease in the USA.

SN Compr Clin Med 2021 Oct 13:1-8. Epub 2021 Oct 13.

Health Sciences Building, 2242, Central Michigan University, Mount Pleasant, MI 48859 USA.

Overall mortality due to congenital heart disease in the United States declined between 1999 and 2017. However, disparities still exist in occurrence and mortality rates among specific racial/ethnic groups in the USA. This study aims to find the association between maternal race and the occurrence of Cyanotic Congenital Heart Disease (CCHD) in the USA. Read More

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October 2021

Prevalence and risk factors of abdominal hernia among Saudi population.

J Family Med Prim Care 2021 Aug 27;10(8):3130-3136. Epub 2021 Aug 27.

Medical Student, College of Medicine, Taif University, Taif, Saudi Arabia.

Objective: Studies assessing prevalence and risk factors of abdominal hernia are scarce in Saudi Arabia, that is why this study aimed to find out the prevalence and risk factors of abdominal hernia among the Saudi Population in 2020.

Methods: A cross-sectional study was done on 500 participants. A pre-designed questionnaire included three sections: Section A consisted of sociodemographic, Section B had items for three dimensions: pain at the site of the hernia or the hernia repair, restriction of activities, cosmetic discomfort; Section C included medical history and other associated risk factors of hernia. Read More

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Congenital Transmission of Apicomplexan Parasites: A Review.

Front Microbiol 2021 29;12:751648. Epub 2021 Sep 29.

Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

Apicomplexans are a group of pathogenic protists that cause various diseases in humans and animals that cause economic losses worldwide. These unicellular eukaryotes are characterized by having a complex life cycle and the ability to evade the immune system of their host organism. Infections caused by some of these parasites affect millions of pregnant women worldwide, leading to various adverse maternal and fetal/placental effects. Read More

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September 2021

Dual burden of Zika and COVID-19 in India: challenges, opportunities and recommendations.

Trop Med Health 2021 Oct 18;49(1):83. Epub 2021 Oct 18.

Kabul University of Medical Sciences, 1001, Kabul, Afghanistan.

The COVID-19 pandemic has wreaked havoc in the world from last year, and any further insults like Zika virus will surely bring the apocalypse unto us. In July 2021, Zika began spreading in India, mainly in the state of Kerala. Zika infection resembles closely COVID-19 and other arboviral infections, which might lead to delayed and misdiagnosis, further leading to underreporting of cases. Read More

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October 2021

Hearing test results of newborns born from the coronavirus disease 2019 (COVID-19) infected mothers: A tertiary center experience in Turkey.

J Obstet Gynaecol Res 2021 Oct 16. Epub 2021 Oct 16.

Obstetrics and Gynecology Department, University of Health Sciences Kartal Dr. Lutfi Kirdar Research and Training Hospital, Istanbul, Turkey.

Objective: Congenital infections can cause newborn hearing loss. Although vertical transmission of coronavirus disease 2019 (COVID-19) infection is theoretically possible, this has not been proven yet. To our knowledge, there is no previous report on whether COVID-19 infection during pregnancy can cause congenital hearing loss. Read More

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October 2021

Prenatal uranium exposure and risk for fetal neural tube defects: A case-control study in women living in a rural area of northern China.

J Hazard Mater 2021 Oct 7;424(Pt B):127466. Epub 2021 Oct 7.

Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China. Electronic address:

The adverse effects of uranium exposure on human health are well-known; less is known, however, regarding its association with congenital malformations. We conducted a case-control study to examine the association between prenatal exposure to uranium and risk for fetal neural tube defects (NTDs) using the concentration of uranium in placental tissue as an exposure marker in 408 NTD cases and 593 healthy controls. Uranium concentration was quantified with an inductively coupled plasma mass spectrometer. Read More

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October 2021

Crinecerfont Lowers Elevated Hormone Markers in Adults with 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia.

J Clin Endocrinol Metab 2021 Oct 15. Epub 2021 Oct 15.

Neurocrine Biosciences, Inc.; El Camino Real, San Diego, CA.

Context: Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is characterized by impaired cortisol synthesis and excess androgen production. Corticotropin-releasing factor type 1 receptor (CRF1R) antagonism may decrease adrenal androgen production.

Objective: To evaluate the safety, tolerability, and efficacy of crinecerfont (NBI-74788), a selective CRF1R antagonist, in 21OHD. Read More

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October 2021

Perinatal and cardiac outcomes of women with hypertrophic cardiomyopathy.

J Matern Fetal Neonatal Med 2021 Oct 15:1-6. Epub 2021 Oct 15.

Department of Obstetrics and Gynecology, Maternal Fetal Medicine Division, University Hospital Centre Sainte-Justine, Montreal, Canada.

Rationale: Pregnancy causes important physiologic stress for women with hypertrophic cardiomyopathy. Data regarding the impact of this condition on obstetrical outcomes is missing.

Objectives: Our objective was to report obstetrical and cardiac outcomes in pregnant women with hypertrophic cardiomyopathy and to assess the possible adverse effects of left ventricular outflow tract obstruction in pregnancy. Read More

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October 2021

WeChat-assisted health education and preoperative care improve the mental state of parents of children with ventricular septal defect.

Psychol Health Med 2021 Oct 15:1-8. Epub 2021 Oct 15.

Department of Cardiac Surgery, Fujian Branch of Shanghai Children's Medical Center, Fuzhou, China.

Many studies have shown that parents of children with congenital heart disease have more stress, anxiety and depression. This study was aimed to explore the effect of implementing WeChat-assisted health education and preoperative care on parents of children with the restrictive ventricular septal defect to improve the psychological state. A prospective randomized controlled study was conducted in a provincial hospital in China. Read More

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October 2021

Leaning towards Cytomegalovirus serological screening in pregnancy to prevent congenital infection: a cost-effectiveness perspective.

BJOG 2021 Oct 15. Epub 2021 Oct 15.

EA7328, Imagine Institut, Université de Paris, Paris, France.

Objective: To assess the cost-effectiveness of prenatal detection of congenital cytomegalovirus (cCMV) following maternal primary infection in the first trimester within standard pregnancy follow-up or involving population-based screening (serological testing at 7 and 12 weeks of gestation), with or without secondary prevention (valaciclovir) in maternal CMV primary infection.

Design, Setting, And Population: From the perspective of the French national health insurance system, cost-effectiveness based on previously published probability estimates and associated plausible ranges that were applied to a hypothetical population of 1,000,000 pregnant women.

Methods: Cost-effectiveness of detecting fetal cCMV in terms of the total direct medical costs involved and associated expected outcomes. Read More

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October 2021

Clinical presentation of simple and combined or syndromic arteriovenous malformations.

J Vasc Surg Venous Lymphat Disord 2021 Oct 11. Epub 2021 Oct 11.

Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

Objectives: Arteriovenous malformations of the lower extremities (AVM) can present as simple or complex combined or syndromic forms (e.g. Parkes Weber Syndrome). Read More

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October 2021

Effect of hysteroscopic metroplasty on reproductive outcomes in women with septate uterus. Systematic review and meta-analysis.

J Minim Invasive Gynecol 2021 Oct 11. Epub 2021 Oct 11.

Hospital Universitario Ramón y Cajal. Madrid, Spain.

Objective: The aim of this systematic review with meta-analysis is to evaluate the impact of hysteroscopic metroplasty on adverse reproductive outcomes such as miscarriage, preterm birth and fetal malpresentation in patients with history of infertility or previous poor obstetrical outcomes.

Data Sources: A systematic electronic search from inception each database up to April 2021 including the following databases was conducted: PubMed-MEDLINE, EMBASE, Web of Science, The Cochrane Library, the CGF Specialized Register of Controlled Trials, Google Scholar and trial registries. A combination of the following keywords was used: `uterine septum´, `septate uterus´, `congenital uterine malformation´, `class 2 uterus´, `class V uterus´, `metroplasty´, `hysteroscopic´, `pregnancy´, `clinical pregnancy´, `ongoing pregnancy´, `miscarriage´, `live birth´, `preterm birth´, `cesarean section´, `cesarean delivery ´ and `fetal malpresentation´. Read More

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October 2021

Patho-Anatomic Spectrum of Branchial Cleft Anomalies: Proposal of Novel Classification System.

J Oral Maxillofac Surg 2021 Sep 17. Epub 2021 Sep 17.

Resident, Department of Pediatric Surgery, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.

Purpose: Histogenesis, nomenclature, and classification of branchial cleft anomalies (BCAs) have been subjects of controversy for decades. The purpose of this study was to investigate the accuracy of current developmental theories (congenital, lymph node, and hybrid "branchial inclusion" theories) in defining the anatomic and histopathological characteristics of BCAs.

Methods: Ninety consecutive patients with BCAs who underwent surgical excision were enrolled in this 2-center retrospective cohort study. Read More

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September 2021

The relationship between religious beliefs and mental state, care burden, and quality of life in parents of infant patients with congenital heart disease.

Cardiol Young 2021 Oct 14:1-5. Epub 2021 Oct 14.

Department of Cardiac Surgery, Fujian Branch of Shanghai Children's Medical Center, Fuzhou, China.

Objective: To evaluate the relationship between religious beliefs and mental state, care burden, and quality of life in parents of infantile patients with CHD.

Methods: A cross-sectional study was conducted at a provincial hospital in Fujian, China. In this study, 114 parents of infant patients with CHD were successfully enrolled. Read More

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October 2021

[ALPK3 gene-related pediatric cardiomyopathy with craniofacial-skeletal features: a report and literature review].

Zhonghua Er Ke Za Zhi 2021 Sep;59(9):787-792

Pediatric Cardiac Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

To explore the clinical characteristics and mutation spectrum of ALPK3-related pediatric cardiomyopathy and craniofacial-skeletal abnormalities in children. The clinical data during a follow-up of 11 years including clinical features, echocardiogram, electrocardiogram, cardiac magnetic resonance, genetic testing, and other data of a child firstly diagnosed with ALPK3 gene-related cardiomyopathy and craniofacial-skeletal abnormalities in China were collected retrospectively. The literatures containing the keyword of "ALPK3 gene" published in the China National Knowledge Infrastructure, Wanfang database and PubMed were collected up to November 2020. Read More

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September 2021

[Interim follow-up of fetal cardiac intervention in five fetuses with pulmonary atresia with intact ventricular septum].

Zhonghua Er Ke Za Zhi 2021 Sep;59(9):782-786

Department of Obstetrics, Women and Children's Hospital, Qingdao University, Qingdao 266034, China.

To summarize the interim outcome and right heart development of pulmonary atresia with intact ventricular septum (PA-IVS) in children after fetal cardiac intervention (FCI). The clinical data of 5 live births underwent FCI from October 2018 to April 2019 in Women and Children's Hospital, Qingdao University were analyzed retrospectively. The development of right ventricle (RV) and tricuspid valve (TV) in uterus after FCI, at birth, the age of 6 months, 1 year and 2 years, and the final outcome were assessed. Read More

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September 2021

Asthma and allergies in offspring conceived by ART: a systematic review and meta-analysis.

Hum Reprod Update 2021 Oct 13. Epub 2021 Oct 13.

Division of Obstetrics and Gynaecology, University of Western Australia, Perth, Western Australia, Australia.

Background: Currently, 1 in 25 children born in Australia are conceived through ARTs such as IVF and ICSI. Worldwide over 8 million children have been born after ART. There is evidence that these children are at an increased risk of congenital malformations, preterm birth, low birth weight and neonatal morbidity. Read More

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October 2021

Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).

Int J Mol Sci 2021 Sep 29;22(19). Epub 2021 Sep 29.

Laboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland.

Endometriosis is a "mysterious" disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed. It is believed that the primary mechanism of the formation of endometriosis foci is retrograde menstruation, i. Read More

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September 2021

Maternal and neonatal complications in women with congenital heart disease: a nationwide analysis.

Eur Heart J 2021 Oct 12. Epub 2021 Oct 12.

Department of Cardiology III, Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.

Aims: The aim of this study was to provide population-based data on maternal and neonatal complications and outcome in the pregnancies of women with congenital heart disease (CHD).

Methods And Results: Based on administrative data from one of the largest German Health Insurance Companies (BARMER GEK, ∼9 million members representative for Germany), all pregnancies in women with CHD between 2005 and 2018 were analysed. In addition, an age-matched non-CHD control group was included for comparison and the association between adult CHD (ACHD) and maternal or neonatal outcomes investigated. Read More

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October 2021

Promising perspectives on pregnancy in women with congenital heart disease.

Eur Heart J 2021 Oct 12. Epub 2021 Oct 12.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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October 2021

SLC4A11 mutations causative of congenital hereditary endothelial dystrophy (CHED) progressing to Harboyan syndrome in consanguineous Pakistani families.

Mol Biol Rep 2021 Oct 12. Epub 2021 Oct 12.

Department of Zoology, Faculty of Biological Sciences, Quaid-i-Azam University, University Road, Islamabad, 45320, Pakistan.

Background: Autosomal recessive corneal hereditary endothelial dystrophy (CHED) is a rare congenital disorder of cornea. Mutations in SLC4A11 gene are associated with CHED phenotype. CHED is also an early feature of Harboyan syndrome. Read More

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October 2021

Uterus transplantation worldwide: clinical activities and outcomes.

Curr Opin Organ Transplant 2021 Oct 11. Epub 2021 Oct 11.

Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Göteborg Stockholm IVF-EUGIN, Stockholm, Sweden Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Foch - Faculté de Medicine Paris Ouest (UVSQ), Suresnes, France.

Purpose Of Review: Women with absolute uterine factor infertility, because of uterine absence, or the presence of a nonfunctional uterus, were regarded as being untreatable until 2014 when the first birth following uterus transplantation (UTx) took place in Sweden. This proof-of-concept occurred in a woman with Mayer-Rokitansky-Küster-Hauser syndrome (MRKHs) with congenital uterine absence, who received a uterus from a 61-year-old live donor (LD). Since then, several births after UTx have occurred in Sweden and subsequently in other countries, including both LD and deceased donor (DD) transplants. Read More

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October 2021

Ethics in prenatal consultation for surgically correctable anomalies and fetal intervention.

Semin Pediatr Surg 2021 Oct 4;30(5):151102. Epub 2021 Sep 4.

Division of Pediatric Surgery, Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, United States; Northwestern University, Feinberg School of Medicine, United States. Electronic address:

Pediatric surgeons play an essential role in prenatal consultation for congenital anomalies likely to require surgery in the newborn period. The involvement of pediatric surgeons during multi-disciplinary prenatal meetings has been an important part of the evolution of comprehensive fetal care, characterized by detailed prenatal evaluation, diagnosis, prognosis, and planned perinatal and post-natal care. Advances in fetal diagnostics and treatments, as well as complex postnatal medical care and decision-making create a broad range of care options for pregnant women with fetal surgical anomalies. Read More

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October 2021

Congenital hemophilia A with low activity of factor XII: a case report and literature review.

Ital J Pediatr 2021 Oct 11;47(1):204. Epub 2021 Oct 11.

Department of Neonatology, Maoming People's Hospital, Weimin Road, Maonan District, Maoming, 525000, Guangdong, China.

Background: Congenital hemophilia A is a recessive inherited hemorrhagic disorder. According to the activity of functional coagulation factors, the severity of hemophilia A is divided into three levels: mild, moderate and severe. The first bleeding episode in severe and moderate congenital hemophilia A occurs mostly in early childhood and mainly involves soft tissue and joint bleeds. Read More

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October 2021

Caring for children with Congenital Zika Syndrome: The unmet needs of mothers in Southern Colombia.

Glob Public Health 2021 Oct 11:1-12. Epub 2021 Oct 11.

Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, University of Lleida, Lleida, Spain.

In Latin America, the Zika virus (ZIKV) epidemic of 2015-2016 resulted in children being born with a spectrum of neurological disorders called Congenital Zika Syndrome (CZS). Women are the primary caregivers of those children. The objective of the study was to identify the perceived needs of women to care for their children with CZS in Southern Colombia. Read More

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October 2021

Outcomes of the Surgical Management of Atrial Isomerism and Functional Single Ventricle: A Single-Centered Cohort From China.

Front Cardiovasc Med 2021 22;8:664752. Epub 2021 Sep 22.

Department of Cardiovascular Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong, China.

The management of atrial isomerism with complex congenital heart disease remains challenging. Experience has been largely obtained in advanced countries. The clinical diversity is greater in China. Read More

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September 2021

Skeletal manifestations of congenital syphilis: Rare but clinically relevant.

Radiol Case Rep 2021 Dec 1;16(12):3635-3637. Epub 2021 Oct 1.

Department of Radiology, Sabah Women & Children's Hospital, Kota Kinabalu, Sabah, Malaysia.

Congenital syphilis occurs as a result of maternal transmission of in utero. This condition is mainly diagnosed by treponemal and non-treponemal serologic tests. However, both maternal nontreponemal and treponemal IgG antibodies can be transferred through the placenta to the fetus, thus complicating its interpretation soon after birth. Read More

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December 2021