Commun Biol 2021 Mar 26;4(1):423. Epub 2021 Mar 26.
Normal and Pathological Development of Melanocytes, Institut Curie, CNRS UMR3347, Inserm U1021, Université PSL, Orsay, France.
Skin pigmentation is dependent on cellular processes including melanosome biogenesis, transport, maturation and transfer to keratinocytes. However, how the cells finely control these processes in space and time to ensure proper pigmentation remains unclear. Here, we show that a component of the cytoplasmic dynein complex, Dynlt3, is required for efficient melanosome transport, acidity and transfer. Read More