10,683 results match your criteria wilcoxon signed


Scatter-to-primary ratio in dentomaxillofacial cone-beam CT: effect of field of view and beam energy.

Dentomaxillofac Radiol 2021 Apr 21:20200597. Epub 2021 Apr 21.

Department of Radiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.

Objective: The aim of this study was to evaluate the effect of field of view (FOV) and beam energy on the scatter-to-primary ratio (SPR) in dental CBCT.

Methods: An anthropomorphic phantom representing an adult male (ATOM Max 711-HN) was scanned using the 3D Accuitomo 170 CBCT (J. Morita, Kyoto, Japan) using 11 FOVs. Read More

View Article and Full-Text PDF

Mechanics of guided growth of the distal femur for correction of fixed knee flexion deformities: an extra-articular technique.

Arch Orthop Trauma Surg 2021 Apr 21. Epub 2021 Apr 21.

Department of Orthopaedic and Trauma Surgery, Assiut University Hospitals, Assiut, Egypt.

Introduction: Anterior distal femoral hemiepiphysiodesis using intra-articular plates for correction of pediatric fixed knee flexion deformities (FKFD) has two documented complications: postoperative knee pain and implant loosening. The aim of this study is to investigate the mechanical properties of a novel extra-articular technique for anterior distal femoral hemiepiphysiodesis in patients with FKFD and to compare them to the conventional technique.

Materials And Methods: Sixteen femoral sawbones were osteotomized at the level of the distal femoral physis and fixed by rail frames to allow linear distraction simulating longitudinal growth. Read More

View Article and Full-Text PDF

Single Center Experience of Sirolimus Therapy in Head and Neck Low-flow Vascular Malformations.

Vasc Endovascular Surg 2021 Apr 21:15385744211010378. Epub 2021 Apr 21.

Department of Vascular Surgery, 4965Royal Free London NHS Foundation Trust, London, United Kingdom.

Objective: Recently, studies have shown that sirolimus is clinically efficacious in the treatment of some low-flow vascular malformations (LFVM). This study aimed to assess the efficacy and safety of sirolimus in treating complex head and neck (H&N) LFVM that were challenging and/or refractory to standard treatment.

Methods: Each patient had baseline and 6-months assessments consisting of clinical history and examination, quality of life (QoL) questionnaires, laboratory investigations, MRI and medical photography. Read More

View Article and Full-Text PDF

Evaluation of the efficacy of laser-assisted flapless corticotomy in accelerating canine retraction: a split-mouth randomized controlled clinical trial.

Oral Maxillofac Surg 2021 Apr 20. Epub 2021 Apr 20.

Department of Orthodontics, University of Damascus Dental School, Damascus, Syria.

Objective: To evaluate the efficacy of laser-assisted flapless corticotomy in the acceleration of canine retraction compared with the conventional technique and to evaluate patients' pain and discomfort levels after corticotomy.

Materials And Methods: A single-center randomized controlled trial was conducted on 18 class II division 1 patients (7 males, 11 females; age range: 16 to 24 years) who required the first-upper-premolar extraction followed by canine retraction. A split-mouth design was used in which the Er:YAG laser-assisted flapless corticotomy was randomly allocated to one side, whereas the other side served as the control side. Read More

View Article and Full-Text PDF

Photoacoustic needle improves needle tip visibility during deep peripheral nerve block.

Sci Rep 2021 Apr 19;11(1):8432. Epub 2021 Apr 19.

Department of Anesthesiology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka City, Tokyo, 181-8611, Japan.

We developed a novel technology using the photoacoustic effect that improve needle tip visibility. We evaluated whether this technology improves needle tip visibility when performing a deep peripheral nerve block in a cadaver model. A photoacoustic needle was developed using a conventional echogenic needle with an intraluminal optical fiber. Read More

View Article and Full-Text PDF

The Influence of Dissonance Induction and Assessment Reactivity in Improving Adherence to COVID-19 Precautionary Measures: A Cluster Randomised Controlled Trial.

Int Dent J 2021 Mar 20. Epub 2021 Mar 20.

Assistant Professor, Department of Periodontics, SIBAR Institute of Dental Sciences, Guntur, AP, India.

Background: During the coronavirus disease 2019 (COVID-19) pandemic, adherence to suggested precautionary measures has been emphasized as important in preventing and curtailing its spread. However, strict adherence to precautionary measures can be demanding.

Methods: This cluster randomised controlled trial done among 1517 undergraduate dental students tested the effectiveness of 'dissonance induction' (DI) and 'assessment reactivity' (AR) in improving adherence to World Health Organization (WHO) measures as compared to a control group. Read More

View Article and Full-Text PDF

[Effect analysis of early application of sequential laser treatment on hypertrophic scar of burn children].

Zhonghua Shao Shang Za Zhi 2021 Mar 24;37:1-6. Epub 2021 Mar 24.

Department of Burn Surgery, the First Hospital of Jilin University, Changchun 130061, China.

To explore the effects of early application of sequential treatment of intensive pulsed light and carbon dioxide laser on burn children. The retrospective cohort before-after study in the same patient was conducted. From January 2016 to December 2018, 145 burn children with hypertrophic scar in the early stage and met the inclusion criteria were admitted to the First Hospital of Jilin University. Read More

View Article and Full-Text PDF

[A prospective randomized controlled study on the effect of balance training on lower limb movement and balance dysfunction in severe burn patients].

Zhonghua Shao Shang Za Zhi 2021 Mar 30;37:1-7. Epub 2021 Mar 30.

Institute of Burns, Tongren Hospital of Wuhan University&Wuhan Third Hospital, Wuhan 430060, China.

To observe the rehabilitation effect of balance training on motor and balance function of lower extremities of deep burn patients. A prospective randomized controlled study was conducted. From January 2016 to January 2020, sixty-four patients with lower limb motor and balance dysfunction after deep burn were admitted to Tongren Hospital of Wuhan University&Wuhan Third Hospital, the burn area was 30% to 70% Total Body Surface Area, and the burn depth of more than one hip, knee and ankle joint of both lower limbs and their periphery were deep second or third degree. Read More

View Article and Full-Text PDF

Identification of patient benefit from proton beam therapy in brain tumour patients based on dosimetric and NTCP analyses.

Radiother Oncol 2021 Apr 16. Epub 2021 Apr 16.

OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Helmholtz Association / Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany. Electronic address:

Background: The limited availability of proton beam therapy (PBT) requires individual treatment selection strategies, such as the model-based approach. In this study, we assessed the dosimetric benefit of PBT compared to photon therapy (XRT), analysed the corresponding changes in normal tissue complication probability (NTCP) on a variety of available models, and illustrated model-based patient selection in an in-silico study for patients with brain tumours.

Methods: For 92 patients treated at two PBT centres, volumetric modulated arc therapy treatment plans were retrospectively created for comparison with the clinically applied PBT plans. Read More

View Article and Full-Text PDF

Effect of Applying Leakage Correction on rCBV Measurement Derived From DSC-MRI in Enhancing and Nonenhancing Glioma.

Front Oncol 2021 23;11:648528. Epub 2021 Mar 23.

Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands.

Purpose: Relative cerebral blood volume (rCBV) is the most widely used parameter derived from DSC perfusion MR imaging for predicting brain tumor aggressiveness. However, accurate rCBV estimation is challenging in enhancing glioma, because of contrast agent extravasation through a disrupted blood-brain barrier (BBB), and even for nonenhancing glioma with an intact BBB, due to an elevated steady-state contrast agent concentration in the vasculature after first passage. In this study a thorough investigation of the effects of two different leakage correction algorithms on rCBV estimation for enhancing and nonenhancing tumors was conducted. Read More

View Article and Full-Text PDF

Photon-Counting Computed Tomography for Coronary Stent Imaging: In Vitro Evaluation of 28 Coronary Stents.

Invest Radiol 2021 Apr 9. Epub 2021 Apr 9.

From the Departments of Diagnostic and Interventional Radiology Internal Medicine I, University Hospital Würzburg, Würzburg Siemens Healthcare GmbH, Forchheim, Germany.

Objectives: The aim of this study was to assess in-stent lumen visibility and quantitative image characteristics of different coronary stents using a novel photon-counting detector (PCD) computed tomography (CT) system in comparison to a state-of-the-art energy-integrating detector (EID) CT scanner.

Materials And Methods: In this in vitro phantom study, 28 different coronary stents ranging from 2.25 to 4. Read More

View Article and Full-Text PDF

The Development of iManage-PC, an Online Symptom Monitoring and Self-management Tool for Men With Clinically Localized Prostate Cancer.

Cancer Nurs 2021 Apr 8. Epub 2021 Apr 8.

Author Affiliations: Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine (Drs Murphy, Schalet, and Victorson and Ms Sauer), Chicago; Bright Outcome (Dr Yang and Ms Hass), Buffalo Grove; Division of Urology, NorthShore University Health System (Drs Novakovic and Helfand), Evanston; and Department of Urology, Northwestern University Feinberg School of Medicine (Dr Nadler), Chicago, Illinois; and Department of Social Sciences and Health Policy, Wake Forest School of Medicine (Dr Murphy), Winston Salem, North Carolina.

Background: Prostate cancer (PC) often impacts 4 major aspects of health-related quality of life (HRQL): urinary, sexual, and bowel dysfunction, and anxiety. Online tools may be helpful in supporting the development of self-management skills that can improve HRQL.

Objective: The aim of this study was to develop and pilot-test an online symptom monitoring and self-management program, iManage-PC. Read More

View Article and Full-Text PDF

Impact of a psychiatry elective on mental health stigma among pharmacy students.

Curr Pharm Teach Learn 2021 Jun 11;13(6):711-716. Epub 2021 Feb 11.

University of California San Diego, Skaggs School of Pharmacy & Pharmaceutical Sciences, 9500 Gilman Dr, La Jolla, CA 92093, United States.

Background And Purpose: Mental health stigma among healthcare providers remains a significant barrier to patients receiving optimal care for psychiatric conditions. This study's purpose is to evaluate the impact of a psychiatry elective on pharmacy students' attitudes toward patients with mental health disorders.

Educational Activity And Setting: This study cohort included pharmacy students enrolled in a Special Topics in Psychiatry elective. Read More

View Article and Full-Text PDF

Transcranial direct current stimulation for balance and gait in repetitive mild traumatic brain injury in rats.

BMC Neurosci 2021 Apr 17;22(1):26. Epub 2021 Apr 17.

Department of Rehabilitation Medicine, College of Medicine, Ewha Womans University, 1071 An-Yang-Cheon Ro, Yang-Cheon Gu, Seoul, 07985, Republic of Korea.

Background: Balance impairment and lack of postural orientation are serious problems in patients with repetitive mild traumatic brain injury (mTBI).

Objective: To investigate whether anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) can improve balance control and gait in repetitive mTBI rat models.

Methods: In this prospective animal study, 65 repetitive mTBI rats were randomly assigned to two groups: the tDCS group and the control group. Read More

View Article and Full-Text PDF

The effectiveness of PROLOTHERAPY for recalcitrant Medial TIBIAL Stress Syndrome: a prospective consecutive CASE series.

J Foot Ankle Res 2021 Apr 16;14(1):32. Epub 2021 Apr 16.

Centre for Sports and Exercise Medicine, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.

Background: Medial tibial stress syndrome (MTSS) is one of the most common lower leg injuries in sporting populations. It accounts for between 6 and 16% of all running injuries, and up to 53% of lower leg injuries in military recruits. Various treatment modalities are available with varying degrees of success. Read More

View Article and Full-Text PDF

Chemoradiation-induced changes in systemic inflammatory markers and their prognostic significance in oesophageal squamous cell carcinoma.

Br J Radiol 2021 Apr 16:20200314. Epub 2021 Apr 16.

Department of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, Singapore.

Objective: Chemoradiation (CRT) may induce a change in systemic inflammatory state which could affect clinical outcomes in oesophageal cancer. We aimed to evaluate the changes and prognostic significance of systemic inflammatory markers following definitive CRT in oesophageal squamous cell carcinoma.

Methods: A total of 53 patients treated with concurrent CRT were included in this retrospective analysis. Read More

View Article and Full-Text PDF

MR imaging of the quadriceps femoris tendon: distal tear characterization and clinical significance of rupture types.

Eur Radiol 2021 Apr 16. Epub 2021 Apr 16.

Department of Radiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI, 48103, USA.

Objective: To characterize quadriceps femoris tendon tears on magnetic resonance (MR) imaging regarding tear extent, location, and presence of bony avulsion.

Materials And Methods: IRB approval was obtained and informed consent was waived for this retrospective case series. Electronic medical records from all patients in our hospital system were searched for keywords: knee MR imaging, and quadriceps tendon rupture or tear. Read More

View Article and Full-Text PDF

Maternal knowledge of the child's heart defect over a 1-year time span, its development and associated factors.

Cardiol Young 2021 Apr 16:1-10. Epub 2021 Apr 16.

Medical Sociology Unit, Hannover, Hannover Medical School, Hannover, Germany.

Background: Mothers are the link between patients, physicians, and other caregivers. Therefore, they should be well informed about the child's heart defect and accompanying issues. This study aimed to assess the mothers' understanding of their child's heart defect at hospitalisation and one year later and to analyse the individual development and associated factors. Read More

View Article and Full-Text PDF

Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study.

Nutr Metab (Lond) 2021 Apr 15;18(1):41. Epub 2021 Apr 15.

Phynova Group Ltd, 16 Fenlock Court, Blenheim Office Park, Long Hanborough, OX29 8LN, UK.

Background: There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycaemia. Significant health-related lifestyle changes are often difficult to implement and functional ingredients that can reduce glycaemic and insulaemic responses may help at risk populations. The aim of this study was to investigate whether a mulberry leaf extract could lower the glycaemic and insulinaemic responses to 75 g sucrose in healthy individuals. Read More

View Article and Full-Text PDF

The diagnostic and prognostic value of H2AFY in hepatocellular carcinoma.

BMC Cancer 2021 Apr 15;21(1):418. Epub 2021 Apr 15.

Department of Technology Education Training, Luzhou People's Hospital, Section 2 of JiuGu Avenue, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.

Background: The potential correlation between H2AFY (also known as MacroH2A1) and the clinical characteristics of hepatocellular carcinoma (HCC) patients was analysed through gene expression profiles and clinical data in The Cancer Genome Atlas (TCGA) database, and the diagnostic and prognostic value of H2AFY in HCC was discussed.

Methods: The gene expression data of HCC and the corresponding clinical characteristics of HCC patients were downloaded from the TCGA database. The differences in H2AFY in normal liver tissues and HCC were analysed. Read More

View Article and Full-Text PDF

Disruption of Pharmacotherapy During the Transition from Adolescence to Early Adulthood in Patients with Attention-Deficit/Hyperactivity Disorder: A Claims Database Analysis Across the USA.

CNS Drugs 2021 Apr 15. Epub 2021 Apr 15.

Takeda Pharmaceuticals USA, 95 Hayden Ave, Lexington, MA, 02421, USA.

Background And Objective: Attention-deficit/hyperactivity disorder (ADHD) treatment rates in adults are low, possibly owing to discontinuation of pediatric care due to various circumstances (including inadequate health insurance coverage, poor disease insight, and patient/family resistance, as well as those who manage their ADHD independent of pharmacologic intervention) during the transition from adolescence to adulthood. To improve the understanding of treatment patterns during this transition, this study characterized pharmacotherapy use in patients with ADHD aged 16-21 years.

Methods: A retrospective claims analysis of the IBM MarketScan Commercial Databases, which represent all census regions of the USA, included patients aged 16-21 years with two or more ADHD diagnoses between 1/1/2008 and 12/31/2017 (one or more diagnoses during the year of age 17) who were continuously enrolled from ages 16-21 years and prescribed ADHD medication for ≥ 6 months at age 17 years. Read More

View Article and Full-Text PDF

Automatic segmentation of corneal dystrophy on photographic images based on texture analysis.

Int Ophthalmol 2021 Apr 15. Epub 2021 Apr 15.

Department of Ophthalmology, Kyung Hee University Medical Center, Kyung Hee University Hospital, Kyung Hee University, #23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 130-872, Korea.

Purpose: To develop an automatic algorithm to analyze dystrophic lesions on photographic images of corneal dystrophy.

Methods: The dataset included 32 images of corneal dystrophy. The dystrophic area was manually segmented twice. Read More

View Article and Full-Text PDF

Radiation dose reduction with the wide-volume scan mode for interstitial lung diseases.

Eur Radiol 2021 Apr 15. Epub 2021 Apr 15.

Department of Radiology, Bichat Claude-Bernard Hospital, APHP, 46 rue Henri Huchard, F-75018, Paris, France.

Objectives: The wide-volume mode, available on wide-area detector row CTs, has the advantage of reducing exposure time and radiation dose. It is infrequently used for lung diseases. The purpose of this study is to compare image quality and radiation dose of wide-volume chest CT to those of standard helical CT in the setting of interstitial lung diseases. Read More

View Article and Full-Text PDF

Free-Breathing Motion-Corrected Single-Shot Phase-Sensitive Inversion Recovery Late-Gadolinium-Enhancement Imaging: A Prospective Study of Image Quality in Patients with Hypertrophic Cardiomyopathy.

Korean J Radiol 2021 Apr 1. Epub 2021 Apr 1.

Department of Radiology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.

Objective: Motion-corrected averaging with a single-shot technique was introduced for faster acquisition of late-gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging while free-breathing. We aimed to evaluate the image quality (IQ) of free-breathing motion-corrected single-shot LGE (moco-ss-LGE) in patients with hypertrophic cardiomyopathy (HCM).

Materials And Methods: Between April and December 2019, 30 patients (23 men; median age, 48. Read More

View Article and Full-Text PDF

Symmetry of crown widths in subjects with unilateral maxillary lateral incisor agenesis.

J Orofac Orthop 2021 Apr 14. Epub 2021 Apr 14.

Department of Orthodontics, Faculty of Dentistry, Hacettepe University, Sihhiye, 06100, Ankara, Turkey.

Purpose: The aim of this study was to compare mesiodistal width and symmetry of maxillary and mandibular teeth in subjects with and without unilateral maxillary lateral incisor agenesis.

Patients And Methods: The study group consisted of 31 patients with unilateral maxillary lateral incisor agenesis (19 females, 12 males, mean age: 16.55 ± 5. Read More

View Article and Full-Text PDF

Effect of Benson's relaxation techniques on blood glucose levels in patients with diabetes mellitus.

Enferm Clin 2021 Apr;31 Suppl 2:S454-S456

Faculty of Nursing STIKes Yatsi, Tangerang, Banten, Indonesia.

This study aimed to determine the effect of Benson's relaxation techniques on blood glucose levels in patients with diabetes mellitus. This study is a quasi-experiment using a pre/posttest design with a control group. A sample of 30 individuals at risk of diabetes was divided into intervention and control groups. Read More

View Article and Full-Text PDF

Mindfulness Matters: Utilization and Perceptions of Mindfulness Practices Among Athletic Trainers.

J Athl Train 2021 Apr 13. Epub 2021 Apr 13.

Appalachian State University, Boone, NC.

Context: Mindfulness practices are effective for injury/illness recovery, decreasing stress and anxiety, and strengthening emotional resilience. They are also beneficial for healthcare professionals' well-being and improved patient outcomes and safety. However, mindfulness has not been studied in athletic trainers. Read More

View Article and Full-Text PDF

Myocardial T1 Values at 1.5 T: Normal Values for General Electric Scanners and Sex-Related Differences.

J Magn Reson Imaging 2021 Apr 13. Epub 2021 Apr 13.

Magnetic Resonance Imaging Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy.

Background: No data are available about normal ranges for native T1 in human myocardium using General Electric (GE) scanners.

Purpose: To establish normal ranges for myocardial T1 values and evaluate regional variability and the influence of physiological factors.

Study Type: Prospective. Read More

View Article and Full-Text PDF

Incongruous effect of phenylephrine on changes in cerebral blood volume measured by near-infrared spectroscopy (NIRS) indicating extracranial contamination.

J Clin Monit Comput 2021 Apr 12. Epub 2021 Apr 12.

Department of Anesthesia, University Hospital Ghent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.

We assessed extracranial contamination of the near-infrared spectroscopy (NIRS) signal during administration of phenylephrine. The study was performed with NIRO 200NX which employs both the Modified Beer-Lambert (MBL) method to measure total hemoglobin (tHb, expressed in µM), and Spatially Resolved Spectroscopy (SRS) to measure total hemoglobin content (nTHI, expressed in arbitrary units (a.u. Read More

View Article and Full-Text PDF

Comparison of Patient-Reported and Caregiver-Reported Swallowing-Related Quality of Life in Parkinson's Disease.

Dysphagia 2021 Apr 12. Epub 2021 Apr 12.

Department of Speech Pathology and Audiology, University of South Alabama, HAHN 1119, 5721 USA Drive North, Mobile, AL, 36688, USA.

This pilot study explored agreement on swallowing-related quality-of-life scores reported by individuals with Parkinson's disease (PD) and their caregivers. Thirty-six patient-caregiver pairs completed the Swallowing Quality of Life Questionnaire (SWAL-QOL) using an online survey format. Additional background and clinical information was ascertained. Read More

View Article and Full-Text PDF