115,332 results match your criteria weight pregnancy


Comparative study of pregnancy outcomes in women with inflammatory bowel disease treated with thiopurines and/or anti-TNF: a French nationwide study 2010-2018.

Aliment Pharmacol Ther 2021 Jun 23. Epub 2021 Jun 23.

EPIPHARE, Épidémiologie des produits de santé, ANSM-CNAM, Denis, France.

Background: Data about thiopurines or anti-TNF use during pregnancy in women with inflammatory bowel diseases (IBD) are reassuring. However, many studies are based upon small sample sizes.

Aims: To assess IBD medication safety during pregnancy. Read More

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Risk factors for the lack of adherence to breastfeeding.

Rev Assoc Med Bras (1992) 2021 Jan;67(1):107-114

Centro Universitário Saúde ABC - Santo André (SP), Brasil.

Objective: To evaluate the prevalence of breastfeeding in a metropolitan region in Brasil and to identify factors influencing the lack of adherence to exclusive breastfeeding for 6 months and total breastfeeding for 2 years.

Methods: In this cross-sectional study, demographic and socioeconomic characteristics of mothers and children in pediatric outpatient clinics were analyzed. Logistic regression was performed using the backward stepwise method to analyze factors associated with the lack of breastfeeding compliance. Read More

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January 2021

What are the causes for low birthweight in Japan? A single hospital-based study.

PLoS One 2021 23;16(6):e0253719. Epub 2021 Jun 23.

Department of Obstetrics and Gynaecology, Keio University School of Medicine, Tokyo, Japan.

Low-birthweight (LBW; <2,500 g) babies are at a higher risk of poor educational achievement, disability, and metabolic diseases than normal-birthweight babies in the future. However, reliable data on factors that contribute to LBW have not been considered previously. Therefore, we aimed to examine the distribution of the causes for LBW. Read More

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Burden of Rubella virus infection among females attending tertiary care hospitals of Odisha, India: a need for adult women vaccination.

Hum Vaccin Immunother 2021 Jun 23:1-4. Epub 2021 Jun 23.

Division of Virology, ICMR-Regional Medical Research Centre, Bhubaneswar, India.

Rubella is a contagious disease caused by rubella virus leading to adverse outcomes among pregnant women including abortions, low birth weight, stillbirths and congenital rubella syndrome (CRS) in the baby. If not pregnant, the clinical manifestations are mild and self-limiting. In this hospital based cross-sectional study, 1985 blood samples were collected from females attending outpatient services of various hospitals to serologically detect Rubella infection. Read More

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Meta-analysis on aspirin combined with low-molecular-weight heparin for improving the live birth rate in patients with antiphospholipid syndrome and its correlation with d-dimer levels.

Medicine (Baltimore) 2021 Jun;100(25):e26264

The Department of Clinical Laboratory Medicine, Yongchuan Hospital, Chongqing Medical University, Yongchuan, Chongqing, China.

Background: Antiphospholipid antibody syndrome (APS) is a systemic, autoimmune, prothrombotic disease characterized by persistent antiphospholipid antibodies, thrombosis, recurrent abortion, complications during pregnancy, and occasionally thrombocytopenia. At present, there is no consensus on the treatment of this disease. Long-term anticoagulation is recommended in most cases in patients with thrombotic APS. Read More

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ELECTROCARDIOGRAPHIC CHANGES IN NEWBORNS FROM MOTHERS WITH METABOLIC SYNDROME.

Wiad Lek 2021 ;74(6):1349-1354

POLTAVA STATE MEDICAL UNIVERSITY, POLTAVA, UKRAINE.

Objective: The aim: Analysis of electrocardiographic parameters in newborns from mothers with metabolic syndrome.

Patients And Methods: Materials and methods: We conducted a prospective cohort trial of 125 newborns, which included the study of their anthropometric, clinical and laboratory indicators and, in particular, ECG parameters. The main group consisted of 40 children, born from mothers with diagnosed metabolic syndrome, the comparison group included 2 subgroups: 28 term newborn and 57 preterm, from mothers without metabolic syndrome. Read More

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Ultrasound prediction of adverse outcome and perinatal complications at diagnosis of late-onset fetal growth restriction: a cohort study.

Ultrasound Obstet Gynecol 2021 Jun 22. Epub 2021 Jun 22.

Department of Medicine and Surgery, Unit of Surgical Sciences, Obstetrics and Gynecology, University of Parma, Italy.

Background: Abnormal umbilical, cerebral and uterine artery Doppler findings and fetal biometry below the 3 percentile have been proposed as risk factors for perinatal complications in late-onset fetal growth restriction (FGR). Recent evidence has allowed to reach a consensus on the clinical use of Doppler ultrasound for the monitoring and timing of delivery in early-onset FGR, however there is limited data on the relationship between abnormal Doppler and severity of the growth restriction and adverse outcome when a diagnosis of late-onset FGR is made.

Objective: To evaluate the relationship between the ultrasound parameters measured at diagnosis and perinatal adverse outcome within a cohort of late-onset FGR fetuses. Read More

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Different Protein Sources in the Maternal Diet of the Rat during Gestation and Lactation Affect Milk Composition and Male Offspring Development during Adulthood.

Reprod Sci 2021 Jun 22. Epub 2021 Jun 22.

Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Vasco de Quiroga 15, Sección XVI, Tlalpan, 14080, México City, D.F, México.

Protein sources in maternal diet are important for mammary gland differentiation and milk protein; however, few studies have examined the metabolic and cellular adaptations of mothers based on protein source diets during pregnancy and lactation, and leptin concentration in offspring. We evaluated metabolic parameters and maternal key organs and milk components in mothers at the end of lactation, who were fed different sources of proteins. In postnatal day 110 and 250, we studied development parameters and leptin in male offspring. Read More

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MiR-590-3p and its targets VEGF, PIGF, and MMP9 in early, middle, and late pregnancy: their longitudinal changes and correlations with risk of fetal growth restriction.

Ir J Med Sci 2021 Jun 22. Epub 2021 Jun 22.

Department of Gynecology, Shanghai First Maternity and Infant Hospital, 2699 West Gaoke Road, Shanghai, 201204, China.

Aims: The term "fetal growth restriction (FGR)" is commonly used to describe fetuses with an estimated fetal weight that is less than 10th percentile for gestational age. This study aimed to investigate the longitudinal change of microRNA-590-3p (miR-590-3p), vascular endothelial growth factor (VEGF), placental growth factor (PIGF), and matrix metalloproteinase (MMP)9 expressions in early, middle, and late pregnancy, and their correlations with the fetal growth restriction (FGR) risk.

Methods: Totally, 970 pregnant women in early pregnancy were enrolled, and their plasma samples were, respectively, acquired in early pregnancy (at 10th or 11th week of gestational age), middle pregnancy (at 20th or 21st week of gestational age), and late pregnancy (at 33th or 34th week of gestational age) for miR-590-3p, VEGF, PIGF, and MMP9 determinations. Read More

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Knowledge, Perception and Practice towards the Risks of Excessive Weight Gain during Pregnancy among Pregnant Mothers at Myung Sung Christian Medical General Hospital, Addis Ababa, Ethiopia.

Ethiop J Health Sci 2021 Mar;31(2):371-380

St. Paul's Hospital Millennium Medical College, Research Directorate.

Background: Being overweight and obese represents a severe public health deterioration affecting all population in general and vulnerable groups, such as pregnant women in particular. This study aimed to assess the knowledge, perception and practice towards the risks of excessive weight gain during pregnancy among pregnant mothers at Myung Sung Christian Medical General Hospital.

Methods: An institution based cross-sectional study was conducted from July to August, 2019. Read More

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The in-utero experience of piglets born from sows with lameness shapes their life trajectory.

Sci Rep 2021 Jun 22;11(1):13052. Epub 2021 Jun 22.

Center for Comparative Studies in Sustainability, Health and Welfare, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of São Paulo, Campus Fernando Costa, Av. Duque de Caxias Norte, 225 Caixa Postal 23, Pirassununga, SP, CEP 13635-900, Brazil.

Experiences during gestation can alter the mother's behavior and physiology, thereby potentially affecting the behavioral and physiological development of the offspring. In livestock, one common challenge for pregnant animals is lameness: a multifactorial condition that causes pain, stress, resulting in poor welfare outcomes. Since maternal pain can affect offspring development, we aimed to quantify the behavioral response in 142 piglets born from sows with different degrees of lameness during pregnancy. Read More

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Fetal growth standards for Chinese twin pregnancies.

BMC Pregnancy Childbirth 2021 Jun 22;21(1):436. Epub 2021 Jun 22.

Department of Fetal Medicine and Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, 2699 West Gaoke Rd, Shanghai, 201204, China.

Background: The common use of singleton fetal growth standard to access twin growth might lead to over-monitoring and treatment. We aimed to develop fetal growth standards for Chinese twins based on ultrasound measurements, and compare it with Zhang's and other twin fetal growth charts.

Methods: A cohort of uncomplicated twin pregnancies were prospectively followed in 2014-2017. Read More

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Severe Maternal Morbidity and Mortality During Delivery Hospitalization of Class I, II, III, and Super Obese Women.

Am J Obstet Gynecol MFM 2021 Jun 19:100420. Epub 2021 Jun 19.

Yale School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, New Haven, Connecticut.

Background: Previous studies show that obesity predisposes patients to higher risks of adverse pregnancy outcomes. Data on the relationship between increasing degrees of obesity and risks of severe maternal morbidity (SMM), including mortality, are limited.

Objective: We examined the association of increasing classes of obesity, especially super obesity, with the risk of SMM and mortality at the time of delivery hospitalization. Read More

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Long-term growth in offspring of infertile parents: a 20-year follow-up study.

Acta Obstet Gynecol Scand 2021 Jun 22. Epub 2021 Jun 22.

Department of Obstetrics and Gynecology, Aalborg University Hospital, Aalborg, Denmark.

Introduction: Long-term growth has been poorly investigated in boys and girls born by parents receiving fertility treatment. This study aimed to investigate the growth of children born following fertility treatment up to adulthood hypothesizing comparable growth in children born by parents receiving fertility treatment or by subfertile parents conceiving spontaneously to that of children spontaneously conceived by fertile parents.

Material And Methods: In this historical long-term follow-up study the study population consisted of 4151 singletons born at term in the Aarhus Birth Cohort between 1990 and 1992. Read More

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Offspring birthweight and placental weight - does the type of maternal diabetes matter? A population-based study of 319,076 pregnancies.

Acta Obstet Gynecol Scand 2021 Jun 22. Epub 2021 Jun 22.

Department of Obstetrics and Gynecology, Akershus University Hospital, Lørenskog, Norway.

Introduction: Our aim was to estimate the difference in birthweight and in placental weight in pregnancies with type 1 diabetes, type 2 diabetes and gestational diabetes as compared to pregnancies without diabetes.

Material And Methods: By using data from the Medical Birth Registry of Norway during the years 2009-2017, we included 319,076 singleton pregnancies with delivery after the 21 week of pregnancy. We used linear regression analyses to estimate the difference in birthweight and in placental weight in grams (g) in pregnancies with type 1 diabetes, type 2 diabetes, and gestational diabetes, using pregnancies without diabetes as the reference. Read More

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Pregnancy outcomes in children, adolescents, and young adults that survived cancer: A nationwide survey in Japan.

J Obstet Gynaecol Res 2021 Jun 21. Epub 2021 Jun 21.

Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Aim: Recent advances in cancer treatment have improved the prognosis of child, adolescent, and young adult (CAYA) cancer survivors. This study aimed to examine the current status of pregnancy outcomes among female cancer survivors in Japan.

Methods: The first questionnaire was sent to 633 major tertiary institutions certified by the Japan Society of Obstetrics and Gynecology to identify institutions managing cases of pregnant cancer survivors between January 2011 and December 2015. Read More

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Paternal exposure to microcystin-LR induces fetal growth restriction partially through inhibiting cell proliferation and vascular development in placental labyrinth.

Environ Sci Pollut Res Int 2021 Jun 21. Epub 2021 Jun 21.

Department of Toxicology & Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei, 230032, China.

Microcystin-leucine arginine (MC-LR) has reproductive and developmental toxicities. Previous studies indicated that gestational exposure to MC-LR induced fetal growth restriction in mice. The aim of this study was to further evaluate the effect of paternal MC-LR exposure before mating on fetal development. Read More

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Recombinant human luteinizing hormone co-treatment in ovarian stimulation for assisted reproductive technology in women of advanced reproductive age: a systematic review and meta-analysis of randomized controlled trials.

Reprod Biol Endocrinol 2021 Jun 21;19(1):91. Epub 2021 Jun 21.

University of Naples Federico II, Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, Naples, Italy.

Introduction: Several studies suggest that luteinizing hormone (LH) could improve IVF outcome in women of advanced reproductive age by optimizing androgen production. In this review, we assessed the role of recombinant-human LH (r-hLH) and recombinant human follicle stimulating hormone (r-hFSH) co-treatment in ovarian stimulation for assisted reproductive technology in women of advanced reproductive age candidates for assisted reproduction.

Material And Methods: Using a preregistered protocol we systematically searched Medline/PubMed, Scopus and the ISI Web of Science databases to identify randomized controlled trials in which r-hFSH monotherapy protocols were compared with r-hFSH/r-hLH co-treatment in women ≥35 years undergoing fresh IVF cycles. Read More

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Pravastatin is useful for prevention of recurrent severe placenta-mediated complications - a pilot study.

J Matern Fetal Neonatal Med 2021 Jun 21:1-7. Epub 2021 Jun 21.

Department of Obstetrics and Gynecology, Lis Hospital for Women, Tel-Aviv Sourasky Medical Center, Tel Aviv University, Tel-Aviv, Israel.

Background: Preeclampsia with severe features and other severe placenta-mediated complications may be life threatening to mother and fetus, especially when they are recurrent. Recurrence of pregnancy complications is common, however, when combined treatment with low molecular weight heparin and low dose aspirin fails, there are not any proven therapeutic options for prevention of recurrence of obstetrical complications.

Objective: We aimed to determine the impact of adding pravastatin to low molecular weight heparin and low dose aspirin for improving pregnancy outcome in women with severe recurrent placenta-mediated complications. Read More

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[Expression of lncRNA MIR210HG in preeclampsia placental tissue and its functional analysis].

Zhonghua Fu Chan Ke Za Zhi 2021 Jun;56(6):425-433

Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.

To investigate the differential expression of long non-coding RNA (lncRNA) in placental tissues of women with preeclampsia (PE) and the effect of MIR210HG on the biological function of HTR8/SVneo cells. A total of 39 cases of PE women (PE group) and 39 cases of normal pregnant women (CTL group) admitted to the Affiliated Hospital of Qingdao University from July 2018 to July 2019 were collected. (1) Transcriptome sequencing (RNA-seq) was used to analyze the differentially expressed lncRNAs in the placental tissues of the two groups. Read More

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Variation in self-identified most stressful life event by outcome of previous pregnancy in a population-based sample interviewed 6-36 months following delivery.

Soc Sci Med 2021 Jun 16;282:114138. Epub 2021 Jun 16.

Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA, 30322, United States.

The majority of health research uses a deductive approach to measure stressful life events, despite evidence that perception of what is stressful varies. The goal of this project was to 1) describe the distribution of self-identified most stressful life events in a cohort of women who experienced a perinatal loss (stillbirth or neonatal death) or live birth in the previous three years and 2) test how childhood adversity influences participant selection of their most stressful life event. We used data from 987 women (282 with stillbirth, 657 without loss, and 48 with a neonatal death in the first 28 days) in the Stillbirth Collaborative Research Network - OASIS (Outcomes after Study Index Stillbirth) follow-up study, a population-based sample set in five U. Read More

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Use of thrombopoietin receptor agonists in pregnancy: A review of the literature.

Hematol Oncol Stem Cell Ther 2021 Jun 16. Epub 2021 Jun 16.

Comphrensive Cancer Center, King Fahad Medical City, Riyadh, Saudi Arabia.

The management of immune thrombocytopenic purpura (ITP) involves several lines of therapy such as corticosteroids and intravenous immunoglobulin. With the emergence of novel therapies such as thrombopoietin receptor agonists (TPO-RAs), there has been a shift in treatment modalities. Eltrombopag and romiplostim have proven to be effective in the management of ITP through clinical studies, but their safety in pregnancy remains uncertain. Read More

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Effects of prenatal and postnatal maternal multiple micronutrient supplementation on child growth and morbidity in Tanzania: a double-blind, randomized-controlled trial.

Int J Epidemiol 2021 Jun 21. Epub 2021 Jun 21.

Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.

Background: Maternal micronutrient status is critical for child growth and nutrition. It is unclear whether maternal multiple micronutrient supplementation (MMS) during pregnancy and lactation improves child growth and prevents child morbidity.

Methods: This study aimed to determine the effects of prenatal and postnatal maternal MMS on child growth and morbidity. Read More

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Maternal first antenatal care visit biometric indices as potential predictors of umbilical cord morphometric parameters.

J Neonatal Perinatal Med 2021 Jun 16. Epub 2021 Jun 16.

Department of Anatomy School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: One key factor proven to increase quality of pregnancy outcome has been antenatal care (ANC) service. The perinatal triad of mother, placenta and fetus becomes functionally complete with a functional umbilical cord. The objective of the study was to establish mathematical models to predict the outcome of umbilical cord morphometric parameters using maternal first antenatal care visit biometric indices. Read More

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Factors associated with the outcome of TOLAC after one previous caesarean section: a retrospective cohort study.

J Obstet Gynaecol 2021 Jun 21:1-7. Epub 2021 Jun 21.

Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India.

The factors associated with the outcome of trial of labour after one previous Caesarean Section; a retrospective cohort study. A retrospective observational study was performed on all eligible consecutive singleton pregnancies planned for trial of labour after one previous Caesarean Section (TOLAC) over a period of 18 months to study the success rate of vaginal birth after Caesarean Section (VBAC) and to find out the factors associated with successful and failed TOLAC. All of the data were entered in electronic format and the data was analysed in detail. Read More

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Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study.

Middle East Fertil Soc J 2021 14;26(1):17. Epub 2021 Jun 14.

Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

Background: The purpose of the present study was to evaluate obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran.

Results: A case-control study was conducted on 55 COVID-19 as the case and 55 matched control pregnant women in Hormozgan, Iran. Patients were considered to be cases if they had a positive COVID-19 test plus a positive chest X-ray result. Read More

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Early pregnancy exposure to metal mixture and birth outcomes - A prospective study in Project Viva.

Environ Int 2021 Jun 17;156:106714. Epub 2021 Jun 17.

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. Electronic address:

Background: Prenatal exposure to metals has been individually associated with birth outcomes. However, little is known about the effect of metal mixture, particularly at low exposure levels.

Objectives: To estimate individual and joint effects of metal mixture components on birth outcomes. Read More

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Associations between a mixture of phenols and phthalates and child behaviour in a French mother-child cohort with repeated assessment of exposure.

Environ Int 2021 Jun 18;156:106697. Epub 2021 Jun 18.

Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble Alpes University, Inserm, CNRS, 38700 La Tronche, France. Electronic address:

Background: Synthetic phenols and phthalates can interfere with biological pathways involved in brain development. Despite the high within-subject temporal variability of urinary concentrations observed for their metabolites, studies investigating effects of phenols and phthalates on child behaviour often relied on a limited number of spot biospecimens to assess exposure. Besides, the majority did not consider mixture effects. Read More

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The effect of music, massage, yoga and exercise on antenatal depression: A meta-analysis.

J Affect Disord 2021 Jun 8;292:592-602. Epub 2021 Jun 8.

Department of Nursing, Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Jiangsu, China. Electronic address:

Background: Prenatal depression affects 20.7 percent of women worldwide, which was associated with preterm birth, low birth weight and Apgar score, as well as cognitive, emotional and behavioral development disorders. We conducted a systematic review and meta-analysis to retrieve the latest and best evidence about music, massage, yoga and exercise in the prevention and treatment of prenatal depression, and to preliminarily compare the four methods to explore the most effective means. Read More

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Gold nanoparticle biodistribution in pregnant mice following intravenous administration varies with gestational age.

Nanomedicine 2021 Jun 17:102412. Epub 2021 Jun 17.

Department of Biomedical Engineering, University of Delaware, Newark, 19716, USA; Department of Materials Science and Engineering, University of Delaware, Newark, 19716, USA; Helen F. Cancer Research & Research Institute, University of Delaware, Newark, 19713, USA. Electronic address:

The use of nanoparticles (NPs) to deliver therapeutics to reproductive organs is an emerging approach to safely and effectively treat mothers and babies facing pregnancy complications. This study investigates the biodistribution of two different sized gold-based NPs in pregnant mice following systemic delivery as a function of gestational age. Poly(ethylene glycol)-coated 15nm gold nanoparticles or 150nm diameter silica core/gold nanoshells were intravenously administered to pregnant mice at gestational days (E)9. Read More

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