91,644 results match your criteria weight gain


Generally rare but occasionally severe weight gain after switching to an integrase inhibitor in virally suppressed AGEhIV cohort participants.

PLoS One 2021 5;16(5):e0251205. Epub 2021 May 5.

Department of Internal Medicine, Amsterdam Infection and Immunity Institute and Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Objectives: Recent studies have reported disproportionate weight gain associated with integrase strand transfer inhibitor (INSTI) initiation in antiretroviral therapy(ART)-naive people with HIV (PWH), particularly among black women. We investigated if HIV-positive AGEhIV participants with suppressed viremia switching to INSTI-containing ART experienced more weight gain compared to HIV-positive virally-suppressed non-switching and HIV-negative controls.

Methods: In the AGEhIV cohort, standardized weight measurements were performed biennially. Read More

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Weight change and glycemic control in type 2 diabetes patients during COVID-19 pandemic: the lockdown effect.

Endocrine 2021 May 5. Epub 2021 May 5.

Endocrinology, Diabetology and Andrology Unit, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy.

Purpose: The aim of this study was to evaluate the impact of the COVID-19 lockdown occurred in Italy from March 9th to May 18th, 2020 on anthropometric parameters and glycemic control in patients with type 2 diabetes mellitus (T2DM).

Methods: One hundred twenty-eight consecutive patients with T2DM (median age 70 years, 74 males) were retrospectively evaluated at the end of the lockdown period. Data on metabolic control were collected at different time: within three months before the lockdown (visit 0) and within the first six weeks after it (visit 1). Read More

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Yeast as growth promoter in two breeds of growing rabbits with special reference to its economic implications.

An Acad Bras Cienc 2021 30;93(2):e20190274. Epub 2021 Apr 30.

Faculty of Veterinary Medicine, Biochemistry Department, Damanhour University, Damanhour, 22511 Egypt.

The present study investigated the effects of dietary supplementation of Saccharomyces cerevisiae (SC) on growth performance, carcass traits, blood biochemical parameters, histological changes in intestinal wall and economic indices in two breeds of weanling rabbits (V-Line and Rex). One-hundred and twenty weaned male rabbits were allotted randomly into four groups in factorial arrangement. The results could be summarized as follows: dietary supplementation of SC significantly accelerated body weight gain (BWG), reduced feed conversion ratio (FCR) and increased profit. Read More

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Haematotoxic effects of methanolic extract of oleo gum resin (frankinccense) in rats.

Sci Prog 2021 Apr-Jun;104(2):368504211015102

Pharmaceutical Services Administration, Health Oasis Hospital, Riyadh, Saudi Arabia.

In several parts of the world, Fluck. is one of the most commonly used herbs for the treatment of arthritis. Its usage should be validated in light of recent findings of haematotoxicity. Read More

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Sizing Up Fontan Failure: Association with Increasing Weight in Adulthood.

Pediatr Cardiol 2021 May 4. Epub 2021 May 4.

Vanderbilt Heart and Vascular Institute, Vanderbilt University Medical Center, Nashville, TN, USA.

Obesity has become increasingly recognized in adults with Fontan palliation, yet the relationship between weight changes in adulthood and Fontan failure is not clearly defined. We hypothesize that increasing weight in adulthood among Fontan patients is associated with the development of Fontan failure. Single-center data from adults with Fontan palliation who were not in Fontan failure at their first clinic visit in adulthood and who received ongoing care were retrospectively collected. Read More

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Late-Onset Mirror Syndrome.

Malays Fam Physician 2021 Mar 15;16(1):129-132. Epub 2021 Feb 15.

MD (UKM) MRCOG (UK), Department of Obstetrics & Gynaecology, School of Medical Sciences, Universiti Sains Malaysia, Malaysia.

Mirror syndrome is a rare clinical condition in pregnancy associated with significant fetal mortality and maternal morbidity. It is characterized by a triad of complications: fetal hydrops, placenta oedema, and maternal oedema. We are reporting one case of late-onset Mirror syndrome in which the patient presented later in the gestation of 36 weeks due to excessive weight gain and clinical sign mimicking preeclampsia. Read More

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High-fat diet induces obesity in adult mice but fails to develop pre-penile and penile vascular dysfunction.

Int J Impot Res 2021 May 4. Epub 2021 May 4.

Department of Physiology, Brody School of Medicine at East Carolina University, Greenville, NC, USA.

Obesity can lead to cardiovascular disease, diabetes, and erectile dysfunction (ED), which decreases overall quality of life. Mechanisms responsible for obesity-induced ED are unknown. Current mouse models of high-fat diet (HFD)-induced obesity yield conflicting results. Read More

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Extensive Rearing Systems in Poultry Production: The Right Chicken for the Right Farming System. A Review of Twenty Years of Scientific Research in Perugia University, Italy.

Animals (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

Department of Agricultural, Food and Environmental Science, University of Perugia, Borgo XX Giugno, 74, 06100 Perugia, Italy.

The demand for poultry meat, being cheaper than red meat, will drive worldwide production of this product. Accordingly, an increase in production up to 16% is expected in 2025, most of which will occur in developing countries. Most poultry meat production is realized with intensive production systems, and extensive rearing systems (ERS) of poultry (organic, free-range, and low-input) represent only a small portion of poultry production in the EU (about 5%). Read More

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Family Food Environment during the COVID-19 Pandemic: A Qualitative Study.

Children (Basel) 2021 Apr 29;8(5). Epub 2021 Apr 29.

Department of Child and Family Science, California State University, Fresno, CA 93740, USA.

Background: The COVID-19 pandemic, with its cyclical lockdown restrictions and school closures, has influenced family life. The home, work, and school environments have collided and merged to form a new normal for many families. This merging extends into the family food environment, and little is known about how families are currently navigating this landscape. Read More

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Natural Autoimmunity to the Thyroid Hormone Monocarboxylate Transporters MCT8 and MCT10.

Biomedicines 2021 Apr 30;9(5). Epub 2021 Apr 30.

Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, D-10115 Berlin, Germany.

The monocarboxylate transporters 8 (MCT8) and 10 (MCT10) are important for thyroid hormone (TH) uptake and signaling. Reduced TH activity is associated with impaired development, weight gain and discomfort. We hypothesized that autoantibodies (aAb) to MCT8 or MCT10 are prevalent in thyroid disease and obesity. Read More

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Effect of Replacing in-Feed Antibiotic Growth Promoters with a Combination of Egg Immunoglobulins and Phytomolecules on the Performance, Serum Immunity, and Intestinal Health of Weaned Pigs Challenged with K88.

Animals (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

State Key Laboratory of Animal Nutrition, Institute of Animal Sciences of Chinese Academy of Agricultural Sciences, No. 2 Yuan Ming Yuan West Road, Beijing 100193, China.

The study was conducted to investigate the effects of replacing antibiotic growth promoters (AGPs) with an egg immunoglobulin (IgY) combined with phytomolecules (PM) on the growth rate, serum immunity, and intestinal health of weaned pigs challenged with K88 ( K88). A total of 192 piglets were weaned at 28 days old with an average weight of 7.29 (± 0. Read More

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Breastfeeding Practices Influence the Breast Milk Microbiota Depending on Pre-Gestational Maternal BMI and Weight Gain over Pregnancy.

Nutrients 2021 Apr 30;13(5). Epub 2021 Apr 30.

Department of Biotechnology, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), 46980 Valencia, Spain.

Breastfeeding is critical for adequate neonatal microbial and immune system development affecting neonate health outcomes in the short and long term. There is a great interest in ascertaining which are the maternal factors contributing to the milk microbiota and the potential relevance for the developing infant. Thus, our study aimed to characterize the effect of mixed and exclusive breastfeeding practices on the milk microbiota and to determine the impact of pre-pregnancy body mass index (BMI) and weight gain over pregnancy on its composition. Read More

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Assisted reproductive technology outcomes in women with a chronic viral disease.

AIDS 2021 Jun;35(7):1073-1081

Université de Paris, Faculté de Médecine.

Objective: The aim of this study was to evaluate the cumulative live birth rate in women undergoing in-vitro fertilization/intracytoplasmic-sperm-injection (IVF/ICSI) according to the type of chronic viral infection [HIV, hepatitis-B virus (HBV) and hepatitis-C virus (HCV)].

Design: A cohort study.

Setting: A tertiary-care university hospital. Read More

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Comparison of Insulin Glargine 300 U/mL versus Glargine 100 U/mL on Glycemic Control and Hypoglycemic Events in East Asian Patients with Type 2 Diabetes: A Patient-level Meta-Analysis of Phase 3 Studies.

Diabetes Res Clin Pract 2021 May 1:108848. Epub 2021 May 1.

Sanofi, Shanghai, China.

Aims: To evaluate efficacy and safety of Gla-300 with Gla-100 in a patient-level meta-analysis among large East Asian patients with type 2 diabetes mellitus (T2DM).

Methods: A patient level meta-analysis of three EDITION studies with similar design and endpoints were conducted over 6-months treatment period. The analysis included 547 patients treated with Gla-300 and 348 patients treated with Gla-100. Read More

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COVID-19-related coagulopathy: a review of pathophysiology and pharmaceutical management.

Cell Biol Int 2021 May 4. Epub 2021 May 4.

Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

December 2019 will never be forgotten in the history of medicine when an outbreak of pneumonia of unknown etiology in Wuhan, China sooner or later prompted the World Health Organization (WHO) to issue a public health warning emergency. This is not the first nor will it be the last time that a member of β-coronaviruses (CoVs) is waging a full-scale war against human health. Notwithstanding the fact that pneumonia is the primary symptom of the novel coronavirus (2019nCoV; designated as SARS-CoV-2), the emergence of severe disease mainly due to the injury of non-pulmonary organs at the shadow of coagulopathy leaves no choice, in some cases, rather than a dreadful death. Read More

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Empagliflozin ameliorates symptoms of diabetes and renal tubular dysfunction in a rat model of diabetes with enlarged kidney (DEK).

PLoS One 2021 4;16(5):e0251135. Epub 2021 May 4.

Laboratory of Veterinary Physiology, Nippon Veterinary and Life Science University, Tokyo, Japan.

Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to reduce hyperglycemia. The present study investigated the effects of a SGLT2 inhibitor, empagliflozin, on hyperglycemia in a novel rat model of non-obesity type 2 diabetes with enlarged kidney (DEK).

Methods: Male DEK rats with non-fasting blood glucose concentrations ≤300 mg/dl and >300 mg/dl were classified as nondiabetic and diabetic, respectively. Read More

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Do Antibiotics Cause Obesity Through Long-term Alterations in the Gut Microbiome? A Review of Current Evidence.

Curr Obes Rep 2021 May 4. Epub 2021 May 4.

Laboratory of Microbiology, Medical School, Democritus University of Thrace, 6th Km Alexandroupolis-Makri, Alexandroupolis, Greece.

Purpose Of Review: In this review, we summarize current evidence on the association between antibiotics and the subsequent development of obesity through modulation of the gut microbiome. Particular emphasis is given on (i) animal and human studies and their limitations; (ii) the reservoir of antibiotics in animal feed, emerging antibiotic resistance, gut dysbiosis, and obesity; (iii) the role of infections, specifically viral infections, as a cause of obesity; and (iv) the potential therapeutic approaches other than antibiotics to modulate gut microbiome.

Recent Findings: Overall, the majority of animal studies and meta-analyses of human studies on the association between antibiotics and subsequent development of obesity are suggestive of a link between exposure to antibiotics, particularly early exposure in life, and the development of subsequent obesity as a result of alterations in the diversity of gut microbiota. Read More

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Growth performances, nutrient digestibility, ruminal fermentation and energy partition of Thai native steers fed exclusive rice straw and fermented sugarcane bagasse with Lactobacillus, cellulase and molasses.

J Anim Physiol Anim Nutr (Berl) 2021 May 3. Epub 2021 May 3.

Department of Animal Science, Faculty of Agriculture, Tropical Feed Resources Research and Development Center (TROFREC), Khon Kaen University, Khon Kaen, Thailand.

The study aimed to evaluate the effect of sugarcane bagasse feeding treated with Lactobacillus casei TH14 (L. casei TH14), cellulase and molasses (BG) on nutrient digestibility, ruminal fermentation, energy partition and growth performances of Thai native steers compared to conventional feeding of rice straw (RS). Eight Thai native steers (144 ± 19. Read More

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Therapeutic use of Guggulsterone in COVID-19 induced obesity (COVIBESITY) and significant role in immunomodulatory effect.

Obes Med 2021 Apr 29:100346. Epub 2021 Apr 29.

SRM College of Pharmacy, SRM IST, Kattankulathur, Kancheepuram, Tamil Nadu, India.

COVID-19 has emerged as a major cause of health crisis around the world. Psychosocial, Behavioral and metabolic changes especially weigh gain, among variety of population was produced in this pandemic, through a variety of mechanisms. Hyperlipidemia is one of the major issues which results in serious cardiovascular complications. Read More

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Young Children's Nutrition During the COVID-19 Pandemic Lockdown: A Comparative Study.

Early Child Educ J 2021 Apr 28:1-9. Epub 2021 Apr 28.

King Saud University, Riyadh, Saudi Arabia.

During the COVID-19 pandemic, most countries took precautionary steps to save their citizens by initiating a lockdown and stopping all social activities by closing schools, companies, entertainment places, markets, gardens, and other social gathering places. As children stayed at home with no physical activities, their weight may have increased. The purpose of this study was to examine the link between fast food, sugars, or soft drinks and the ongoing domestic lockdown of the COVID-19 pandemic. Read More

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Trajectories and determinants of weight gain in two cohorts of young adult women born 16 years apart.

Int J Obes (Lond) 2021 May 3. Epub 2021 May 3.

Centre for Research on Exercise, Physical Activity and Health, School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD, Australia.

Background: The aims were to compare: (1) baseline weights and weight gain trajectories; (2) sociodemographic, behavioural and health characteristics driving weight gain; and (3) estimated average weight in 20 years' time, in two cohorts of young women.

Methods: Data were from 16066 participants in two population-based cohorts of young adult women, born in 1973-78 ("GenX") and 1989-95 ("millennials"). Weight was reported at baseline (age 18-23 in both cohorts) and 4 years later. Read More

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Quetiapine for primary insomnia: Consider the risks.

Cleve Clin J Med 2021 May 3;88(5):286-294. Epub 2021 May 3.

University of Connecticut School of Medicine, Farmington, CT.

The second-generation antipsychotic drug quetiapine (Seroquel) is increasingly being used off-label for treating insomnia in the general population, possibly to avoid standard medications with known addictive qualities and adverse side effects. However, evidence to support using it in this way is scant, and quetiapine is associated with weight gain and other metabolic effects. It must be used cautiously and with appropriate monitoring for adverse effects and abuse. Read More

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Meta-analysis of the effects of essential oil as an alternative to monensin in diets for beef cattle.

Vet J 2021 Jun 23;272:105659. Epub 2021 Mar 23.

Federal University of Espírito Santo, Department of Animal Science, Alegre, ES, Brazil.

Additives used to improve feed efficiency of beef cattle on high-grain diets requires products that not only increase animal performance but also provide food safety for consumers. Since phytogenic additives such as essential oils (EO) are the main substitutes for monensin in the diet of cattle fed high-grain diets, this study aimed to evaluate, through meta-analysis, the effects of EO as an alternative to monensin in diets for beef cattle on feed intake, performance, carcass characteristics and ruminal fermentative parameters. Ten peer-reviewed publications with 27 treatment means were included in the data set. Read More

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Environmental impact of primary beef production chain in Colombia: Carbon footprint, non-renewable energy and land use using Life Cycle Assessment.

Sci Total Environ 2021 Jun 4;773:145573. Epub 2021 Feb 4.

Compañía Nacional de Chocolates, Rionegro, Antioquia, Colombia. Electronic address:

In Colombia, the beef production chain accounts for approximately 11.6 million cattle heads and annually produces 933 million kg of the beef carcass. There are no life cycle assessment (LCA) studies that have evaluated the environmental performance of Colombian beef systems. Read More

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SERUM GLP-2 is Increased in Association with Excess Gestational Weight Gain.

Am J Perinatol 2021 May 3. Epub 2021 May 3.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

Objective:  Obesity in pregnancy bears unique maternal and fetal risks. Obesity has also been associated with chronic inflammation, including elevated serum levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). Higher serum lipopolysaccharide (LPS) levels have been implicated in driving this inflammation, a phenomenon called metabolic endotoxemia (ME). Read More

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Effect of ractopamine hydrochloride on environmental gas emissions, growth performance, and carcass characteristics in feedlot steers.

J Anim Sci 2021 May 3. Epub 2021 May 3.

Department of Animal Science, University of California, Davis, Davis, CA, USA.

With a growing global population and increased environmental concerns around animal agriculture, it is essential to humanely maximize animal performance and reduce environmental emissions. The present study aims to determine the efficacy of feeding ractopamine hydrochloride (RAC), an orally active, β1-adrenergic agonist (β1AA), to feedlot steers in the last 42 d of finishing to reduce ammonia (NH3) emissions and improve animal performance. A randomized complete block design was used to allocate 112 Angus and crossbred Angus steers (Initial BW = 566. Read More

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Estimation of direct and social effects of feeding duration in growing pigs using records from automatic feeding stations.

J Anim Sci 2021 May;99(5)

Department of Animal Science, Michigan State University, East Lansing, MI 48824.

Automatic feeding systems in pig production allow for the recording of individual feeding behavior traits, which might be influenced by the social interactions among individuals. This study fitted mixed models to estimate the direct and social effects on visit duration at the feeder of group-housed pigs. The dataset included 74,413 records of each visit duration time (min) event at the automatic feeder from 135 pigs housed in 14 pens. Read More

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Gut Microbiota Represent a Major Thermogenic Biomass.

Function (Oxf) 2021 15;2(3):zqab019. Epub 2021 Apr 15.

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.

Evidence supports various roles for microbial metabolites in the control of multiple aspects of host energy flux including feeding behaviors, digestive efficiency, and energy expenditure, but few studies have quantified the energy utilization of the biomass of the gut microbiota itself. Because gut microbiota exist in an anoxic environment, energy flux is expected to be anaerobic; unfortunately, commonly utilized O/CO respirometry-based approaches are unable to detect anaerobic energy flux. To quantify the contribution of the gut microbial biomass to whole-animal energy flux, we examined the effect of surgical reduction of gut biomass in C57BL/6J mice via cecectomy and assessed energy expenditure using methods sensitive to anaerobic flux, including bomb and direct calorimetry. Read More

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Effects of exogenous β-glucanase on ileal digesta soluble β-glucan molecular weight, digestive tract characteristics, and performance of coccidiosis vaccinated broiler chickens fed hulless barley-based diets with and without medication.

PLoS One 2021 3;16(5):e0236231. Epub 2021 May 3.

Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Introduction: Limited use of medication in poultry feed led to the investigation of exogenous enzymes as antibiotic alternatives for controlling enteric disease. The objective of this study was to evaluate the effects of diet β-glucanase (BGase) and medication on β-glucan depolymerization, digestive tract characteristics, and growth performance of broilers.

Materials And Methods: Broilers were fed hulless barley (HB) based diets with BGase (Econase GT 200P from AB Vista; 0 and 0. Read More

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Health literacy and its relation to continuing with breastfeeding at six months post-partum in a sample of Spanish women.

Nurs Open 2021 May 3. Epub 2021 May 3.

Nursing Department, Univesitat Jaume I, Castellón, Spain.

Aim: To explore the relation between health literacy (HL) and continuing breastfeeding (BF) at 6 months post-partum.

Design: Observational, longitudinal and prospective study between December 2018-May 2019. The STROBE checklist was used. Read More

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