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Exploring experiences of COVID-19-positive individuals from social media posts.

Int J Nurs Pract 2021 Jun 14:e12986. Epub 2021 Jun 14.

College of Nursing, University of Utah, Salt Lake City, Utah, USA.

Aims: This study aimed to explore the experience of individuals who claimed to be COVID-19 positive via their Twitter feeds.

Background: Public social media data are valuable to understanding people's experiences of public health phenomena. To improve care to those with COVID-19, this study explored themes from Twitter feeds, generated by individuals who self-identified as COVID-19 positive. Read More

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Quality of web-based information at the beginning of a global pandemic: a cross-sectional infodemiology study investigating preventive measures and self care methods of the coronavirus disease 2019.

BMC Public Health 2021 06 14;21(1):1141. Epub 2021 Jun 14.

Department of Women's and Children's Health, Uppsala University, Uppsala University Hospital, SE-75185, Uppsala, Sweden.

Background: reducing the spread and impact epidemics and pandemics requires that members of the general population change their behaviors according to the recommendations, restrictions and laws provided by leading authorities. When a new epidemic or pandemic emerges, people are faced with the challenge of sorting through a great volume of varied information. Therefore, the dissemination of high-quality web-based information is essential during this time period. Read More

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TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data.

Nucleic Acids Res 2021 Jun 14. Epub 2021 Jun 14.

Center for Computational and Molecular Biology, Brown University, Providence, RI 02912, USA.

Uncovering how transcription factors regulate their targets at DNA, RNA and protein levels over time is critical to define gene regulatory networks (GRNs) and assign mechanisms in normal and diseased states. RNA-seq is a standard method measuring gene regulation using an established set of analysis stages. However, none of the currently available pipeline methods for interpreting ordered genomic data (in time or space) use time-series models to assign cause and effect relationships within GRNs, are adaptive to diverse experimental designs, or enable user interpretation through a web-based platform. Read More

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Development and implementation of a novel Web-based gaming application to enhance emergency medical technician knowledge in low- and middle-income countries.

AEM Educ Train 2021 Jul 6;5(3):e10602. Epub 2021 May 6.

Department of Emergency Medicine Stanford University Stanford California USA.

Background: Increasing access to high-quality emergency and prehospital care is an important priority in low- and middle-income countries (LMICs). However, ensuring that emergency medical technicians (EMTs) maintain their clinical knowledge and proficiency with procedural skills is challenging, as continuing education requirements are still being introduced, and clinical instructional efforts need strengthening. We describe the development and implementation of an innovative asynchronous learning tool for EMTs in the form of a Web-based trivia game. Read More

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The relationship between walk score® and perceived walkability in ultrahigh density areas.

Prev Med Rep 2021 Sep 5;23:101393. Epub 2021 May 5.

Faculty of Sport Sciences, Waseda University, Japan.

Walk Score® is a free web-based tool that provides a walkability score for any given location. A limited number of North American studies have found associations between Walk Score® and perceived built environment attributes, yet it remains unknown whether similar associations exist in Asian countries. The study's objective is to examine the covariate-adjusted correlations between the Walk Score® metric and measures of the perceived built environment in ultrahigh density areas of Japan. Read More

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September 2021

Experiences with and Perception of a Web-Based Mindfulness, Nutrition, and Fitness Platform Reported by First-Year University Students: A Qualitative Study.

J Acad Nutr Diet 2021 Jun 9. Epub 2021 Jun 9.

Background: My Viva Plan (MVP) (https://www.myvivainc.com/) is a web-based application developed by a dietitian that aims to support healthy living by providing resources and self-monitoring tools to help promote a healthy diet, healthy mind, and physical fitness. Read More

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Geostatistical analysis, web-based mapping, and environmental determinants of under-5 stunting: evidence from the 2014 Ghana Demographic and Health Survey.

Lancet Planet Health 2021 Jun;5(6):e347-e355

College of Public Health, University of South Florida, Tampa, FL, USA.

Background: Stunting rates in children younger than 5 years are among the most important health indicators globally. At the national level, malnutrition accounts for about 40% of under-5 deaths in Ghana. Disease risk mapping provides opportunities for disease surveillance and targeted interventions. Read More

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NPWT Resource Use Compared With Conventional Wound Treatment in Subcutaneous Abdominal Wounds With Healing Impairment After Surgery: SAWHI Randomized Clinical Trial Results.

Ann Surg 2021 Jun 10. Epub 2021 Jun 10.

Institute for Research in Operative Medicine, University of Witten/Herdecke, Cologne, Germany.

Objective: To compare resource utilization of NPWT and CWT for SAWHI after surgery.

Summary Of Background Data: NPWT is widely used in the management of complex wounds but high-level evidence of its resource use remains sparse.

Methods: The multicenter, multinational, randomized clinical SAWHI study enrolled a total of 539 consecutive, compliant adult patients with SAWHI after surgery without fascial dehiscence between August 2, 2011, and January 31, 2018. Read More

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SC1: A Tool for Interactive Web-Based Single-Cell RNA-Seq Data Analysis.

J Comput Biol 2021 Jun 11. Epub 2021 Jun 11.

Computer Science and Engineering Department, University of Connecticut, Storrs, Connecticut, USA.

Single-cell RNA-Seq (scRNA-Seq) is critical for studying cellular function and phenotypic heterogeneity as well as the development of tissues and tumors. In this study, we present a web-based highly interactive scRNA-Seq data analysis tool publicly accessible at https://sc1.engr. Read More

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A New Web-Based Tool for RTO-Focused Animal Shelter Data Analysis.

Authors:
Tom Kremer

Front Vet Sci 2021 25;8:669428. Epub 2021 May 25.

Minerva Schools at KGI, San Francisco, CA, United States.

Animal shelters are increasingly interested in reducing their intake and helping their communities keep and care for animals. Improving Return-to-Owner (RTO) rates of stray dogs is one path to save significant shelter space, time, and costs and keep animals with their caregivers and communities. Aggregating and visualizing RTO data spatially are useful for identifying trends and highlighting areas for potential interventions. Read More

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Development and Validation of a Practical Model to Identify Patients at Risk of Bleeding After TAVR.

JACC Cardiovasc Interv 2021 Jun;14(11):1196-1206

Department of Diagnostic and Interventional Cardiology, Gabriele Monasterio Tuscany Foundation, G. Pasquinucci Heart Hospital, Massa, Italy.

Objectives: No standardized algorithm exists to identify patients at risk of bleeding after transcatheter aortic valve replacement (TAVR). The aim of this study was to generate and validate a useful predictive model.

Background: Bleeding events after TAVR influence prognosis and quality of life and may be preventable. Read More

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Design and Assessment of a Mobile Health Care Solution for the Military Pediatrician: The DHA Pediatrics App.

Mil Med 2021 Jun 10. Epub 2021 Jun 10.

Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

Introduction: Mobile health technology design and use by patients and clinicians have rapidly evolved in the past 20 years. Nevertheless, the technology has remained in silos of practices, patients, and individual institutions. Uptake across integrated health systems has lagged. Read More

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VirusViz: comparative analysis and effective visualization of viral nucleotide and amino acid variants.

Nucleic Acids Res 2021 Jun 9. Epub 2021 Jun 9.

Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Via Ponzio 34/5, 20133 Milano, Italy.

Variant visualization plays an important role in supporting the viral evolution analysis, extremely valuable during the COVID-19 pandemic. VirusViz is a web-based application for comparing variants of selected viral populations and their sub-populations; it is primarily focused on SARS-CoV-2 variants, although the tool also supports other viral species (SARS-CoV, MERS-CoV, Dengue, Ebola). As input, VirusViz imports results of queries extracting variants and metadata from the large database ViruSurf, which integrates information about most SARS-CoV-2 sequences publicly deposited worldwide. Read More

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Building Primary-School Children's Resilience through a Web-Based Interactive Learning Environment: Quasi-Experimental Pre-Post Study.

JMIR Pediatr Parent 2021 Jun 9;4(2):e27958. Epub 2021 Jun 9.

Dyslexia Centers Limassol, Limassol, Cyprus.

Background: Resilience is a person's mental ability to deal with challenging situations adaptively and is a crucial stress management skill. Psychological resilience and finding ways to cope in crises is a highly relevant topic considering the COVID-19 pandemic, which enforced quarantine, social distancing measures, and school closures worldwide. Parents and children are currently living with increased stress due to COVID-19. Read More

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Needs and Experiences of Users of Digital Navigation Tools for Mental Health Treatment and Supportive Services: Survey Study.

JMIR Ment Health 2021 Jun 9;8(6):e27022. Epub 2021 Jun 9.

Beth Israel Deaconess Medical Center, Boston, MA, United States.

Background: Despite a recent proliferation in web-based and digital resources that are designed to assist users in finding appropriate mental health treatment and supportive services, it can be overwhelming, confusing, and difficult for an individual or family member to access and use an appropriate navigation tool. As digital resources are increasingly sought after, there is an urgent need for a clearer understanding of digital navigation tools in order to help link individuals with the tool that is best suited to their needs.

Objective: The objective of this study was to determine the needs of individuals seeking mental health treatment and supportive services and to quantify their experiences and satisfaction with available digital navigation tools. Read More

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Medical Insights from Posts About Irritable Bowel Syndrome by Adolescent Patients and Their Parents: Topic Modeling and Social Network Analysis.

Authors:
Bu Zhong Qian Liu

J Med Internet Res 2021 Jun 9;23(6):e26867. Epub 2021 Jun 9.

School of Journalism and Communication, National Media Experimental Teaching Demonstration Center, Jinan University, Guangzhou, Guangdong Province, China.

Background: Adolescents with irritable bowel syndrome (IBS) are increasingly seeking and sharing information about their symptoms in web-based health care forums. Their posts and those from their parents contain critical insights that can be used by patients, physicians, and caregivers to manage IBS symptoms.

Objective: The aim of this study is to examine the posts from adolescent patients and their parents in a health forum, IBS Group, to better understand the key challenges, concerns, and issues of interest to young patients with IBS and their caregivers. Read More

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eSkip-Finder: a machine learning-based web application and database to identify the optimal sequences of antisense oligonucleotides for exon skipping.

Nucleic Acids Res 2021 Jun 9. Epub 2021 Jun 9.

Department of Medical Genetics, University of Alberta Faculty of Medicine and Dentistry, 8613-114 St, Edmonton, AB, Canada.

Exon skipping using antisense oligonucleotides (ASOs) has recently proven to be a powerful tool for mRNA splicing modulation. Several exon-skipping ASOs have been approved to treat genetic diseases worldwide. However, a significant challenge is the difficulty in selecting an optimal sequence for exon skipping. Read More

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Perceptions of Racially and Ethnically Diverse Women at High Risk of Breast Cancer Regarding the Use of a Web-Based Decision Aid for Chemoprevention: Qualitative Study Nested Within a Randomized Controlled Trial.

J Med Internet Res 2021 Jun 8;23(6):e23839. Epub 2021 Jun 8.

Columbia University, New York, NY, United States.

Background: Chemopreventive agents such as selective estrogen receptor modulators and aromatase inhibitors have proven efficacy in reducing breast cancer risk by 41% to 79% in high-risk women. Women at high risk of developing breast cancer face the complex decision of whether to take selective estrogen receptor modulators or aromatase inhibitors for breast cancer chemoprevention. RealRisks is a patient-centered, web-based decision aid (DA) designed to promote the understanding of breast cancer risk and to engage diverse women in planning a preference-sensitive course of decision making about taking chemoprevention. Read More

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Adverse event reporting tools and regulatory measures in India through outcome of Pharmacovigilance Programme of India.

Indian J Pharmacol 2021 Mar-Apr;53(2):143-152

Central Drugs Standard Control Organization, North Zone, Ghaziabad, Uttar Pradesh, India.

The primary care medical practitioners as well as common public must be made aware of the importance and benefits of reporting adverse drug reactions (ADRs). The reporting of ADRs through periodic safety update reports is a regulatory requirement in many countries including India, however, the importance of ADR reporting through spontaneous reporting system cannot be ignored. After the initiation of Programme for International Drug Monitoring, WHO-Uppsala Monitoring Centre (UMC), Sweden, succeeded in establishing a worldwide pharmacovigilance (PV) network in >150 countries. Read More

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Web-based, rapid and contactless management of ambulatory patients for SARS-CoV-2-testing.

BMC Infect Dis 2021 Jun 7;21(1):535. Epub 2021 Jun 7.

Department for Clinical affairs and Crisis management, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 62, 50973, Cologne, Germany.

Background: During the SARS-CoV-2 pandemic a mass casualty incident of ambulatory patients occurred at the COVID-19 rapid response infrastructure (CRRI) facility at the University Hospital of Cologne (UHC). We report the development of a patient-centred mobile-device solution to support efficient management of the facility, triage of patients and rapid delivery of test results.

Methods: The UHC-Corona Web Tool (CWT) was developed as a web-based software useable on each patient's smartphone. Read More

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Factors Predicting Trial Engagement, Treatment Satisfaction, and Health-Related Quality of Life During a Web-Based Treatment and Social Networking Trial for Binge Drinking and Depression in Young Adults: Secondary Analysis of a Randomized Controlled Trial.

JMIR Ment Health 2021 Jun 7;8(6):e23986. Epub 2021 Jun 7.

Centre for Brain and Mental Health Research, School of Medicine and Public Health, The University of Newcastle, Callaghan, Australia.

Background: Mental health and alcohol use problems are among the most common causes of disease burden in young Australians, frequently co-occur (comorbidity), and lead to significant lifetime burden. However, comorbidities remain significantly underdetected and undertreated in health settings. Digital mental health tools designed to identify at-risk individuals, encourage help-seeking, or deliver treatment for comorbidity have the potential to address this service gap. Read More

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American Association of Clinical Endocrinology And Associazione Medici Endocrinologi Thyroid Nodule Algorithmic Tool.

Endocr Pract 2021 Jun 2. Epub 2021 Jun 2.

Mayo Clinic College of Medicine, Rochester, Minnesota.

Objective: The first edition of the American Association of Clinical Endocrinology/American College of Endocrinology/Associazione Medici Endocrinologi Guidelines for the Diagnosis and Management of Thyroid Nodules was published in 2006 and updated in 2010 and 2016. The American Association of Clinical Endocrinology/American College of Endocrinology/Associazione Medici Endocrinologi multidisciplinary thyroid nodules task force was charged with developing a novel interactive electronic algorithmic tool to evaluate thyroid nodules.

Methods: The Thyroid Nodule App (termed TNAPP) was based on the updated 2016 clinical practice guideline recommendations while incorporating recent scientific evidence and avoiding unnecessary diagnostic procedures and surgical overtreatment. Read More

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The Development and Usability of the AMPREDICT Decision Support Tool: A Mixed Methods Study.

Eur J Vasc Endovasc Surg 2021 Jun 1. Epub 2021 Jun 1.

VA Puget Sound Health Care System, Seattle, WA, USA; Department of Rehabilitation Medicine, University of Washington, Seattle, WA, United States; VA Centre for Limb Loss and Mobility (CLiMB), Seattle, WA, USA.

Objective: Amputation level decision making in patients with chronic limb threatening ischaemia is challenging. Currently, evidence relies on published average population risks rather than individual patient risks. The result is significant variation in the distribution of amputation levels across health systems, geographical regions, and time. Read More

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Using Virtual Patients to Explore the Clinical Reasoning Skills of Medical Students: Mixed Methods Study.

J Med Internet Res 2021 Jun 4;23(6):e24723. Epub 2021 Jun 4.

Institute of Education, University College London, London, United Kingdom.

Background: Improving clinical reasoning skills-the thought processes used by clinicians to formulate appropriate questions and diagnoses-is essential for reducing missed diagnostic opportunities. The electronic Clinical Reasoning Educational Simulation Tool (eCREST) was developed to improve the clinical reasoning of future physicians. A feasibility trial demonstrated acceptability and potential impacts; however, the processes by which students gathered data were unknown. Read More

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Medical faculty perception toward digital teaching methods during COVID-19 pandemic: Experience from India.

J Educ Health Promot 2021 31;10:95. Epub 2021 Mar 31.

Department of Pharmacology, Parul Institute of Medical Sciences and Research, Parul University, Vadodara, Gujarat, India.

Background: Videoconferencing has been used as a modality of online medical teaching by various institutes. There is a paucity of studies reporting the perception of medical teachers toward teaching using teleconferencing platforms. The objective of this survey was to evaluate the perception of medical teachers toward teaching using videoconferencing platforms such as Zoom meet, Google meet, and Google classroom during the COVID-19 pandemic. Read More

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e-Nature Positive Emotions Photography Database (e-NatPOEM): affectively rated nature images promoting positive emotions.

Sci Rep 2021 Jun 3;11(1):11696. Epub 2021 Jun 3.

Hospital Israelita Albert Einstein, Research Institute, São Paulo, Brazil.

Affectively rated image databases have their main application in studies that require inducing distinct stimuli on subjects. Widespread databases are designed to cover a broad range of stimuli, from negative to positive (valence), and relaxed to excited (arousal). The availability of narrow domain databases, designed to cover and thoroughly analyze a few categories of images that induce a particular stimulus, is limited. Read More

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Patients and Professionals as Partners in Hypertension Care: Qualitative Substudy of a Randomized Controlled Trial Using an Interactive Web-Based System Via Mobile Phone.

J Med Internet Res 2021 Jun 3;23(6):e26143. Epub 2021 Jun 3.

University of Gothenburg Centre for Person-Centred Care, University of Gothenburg, Gothenburg, Sweden.

Background: The use of technology has the potential to support the patient´s active participation regarding treatment of hypertension. This might lead to changes in the roles of the patient and health care professional and affect the partnership between them.

Objective: The aim of this qualitative study was to explore the partnership between patients and health care professionals and the roles of patients and professionals in hypertension management when using an interactive web-based system for self-management of hypertension via the patient's own mobile phone. Read More

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Development and Validation of a Machine-Learning Model for Prediction of Extubation Failure in Intensive Care Units.

Front Med (Lausanne) 2021 17;8:676343. Epub 2021 May 17.

Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.

Extubation failure (EF) can lead to an increased chance of ventilator-associated pneumonia, longer hospital stays, and a higher mortality rate. This study aimed to develop and validate an accurate machine-learning model to predict EF in intensive care units (ICUs). Patients who underwent extubation in the Medical Information Mart for Intensive Care (MIMIC)-IV database were included. Read More

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The European Rare Kidney Disease Registry (ERKReg): objectives, design and initial results.

Orphanet J Rare Dis 2021 Jun 2;16(1):251. Epub 2021 Jun 2.

Department of Renal Medicine, University College London and Paediatric Nephrology Unit, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.

Background: The European Rare Kidney Disease Reference Network (ERKNet) recently established ERKReg, a Web-based registry for all patients with rare kidney diseases. The main objectives of this core registry are to generate epidemiological information, identify current patient cohort for clinical research, explore diagnostic and therapeutic management practices, and monitor treatment performance and patient's outcomes. The registry has a modular design that allows to integrate comprehensive disease-specific registries as extensions to the core database. Read More

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Modelling tool to support decision-making in the NHS Health Check programme: workshops, systematic review and co-production with users.

Health Technol Assess 2021 May;25(35):1-234

Department of Public Health and Policy, University of Liverpool, Liverpool, UK.

Background: Local authorities in England commission the NHS Health Check programme to invite everyone aged 40-74 years without pre-existing conditions for risk assessment and eventual intervention, if needed. However, the programme's effectiveness, cost-effectiveness and equity impact remain uncertain.

Aim: To develop a validated open-access flexible web-based model that enables local commissioners to quantify the cost-effectiveness and potential for equitable population health gain of the NHS Health Check programme. Read More

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