2,401 results match your criteria vur


Clinical management of vesicoureteral reflux with respect to EAU Guidelines: A multicenter study.

Int J Clin Pract 2021 May 9:e14339. Epub 2021 May 9.

Department of Pediatric Urology, Gazi University School of Medicine, Ankara.

Purpose: We designed a multicenter, retrospective study to investigate the current trends in initial management of reflux with respect to European Association of Urology (EAU) Guidelines in Urology clinics of our country.

Materials And Methods: The study group consisted of 1988 renal units (RU) of 1345 patients treated surgically due to vesicoureteral reflux (VUR) (between years 2003-2017 in 9 different institutions. Patients were divided into 2 groups according to time of initial treatment and also grouped according to risk factors by "EAU guidelines on VUR". Read More

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[Diagnosis and surgical treatment of hypospadia in girls].

Authors:
A E Soloviev

Urologiia 2021 May(2):78-81

Ryazan State Medical University, Ryazan, Russia.

Aim: To suggest new method of surgical correction of hypospadias in girls.

Materials And Methods: For 50 years under our supervision there were 220 girls diagnosed with hypospadias of various forms. In the diagnosis used anamnesis, examination, catheterization and cystoscopy of the bladder, vaginoscopy, ultrasound and X-ray research methods. Read More

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Contrast-enhanced voiding urosonography in the assessment of vesical-ureteral reflux: the time has come.

Radiol Med 2021 May 5. Epub 2021 May 5.

Section of Radiological Sciences, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, "G. Martino" Policlinic, Via Consolare Valeria 1, 98100, Messina, Italy.

Vesicoureteral reflux (VUR) is a pathological condition contradistinguished by monolateral or bilateral retrograde flow of urine from the bladder to the ureter and to the kidney. If not properly recognized and treated, VUR can potentially be associated to several complications such as recurrent infections and possible secondary scars with Chronic Kidney Disease (CKD). Furthermore, it represents an important risk factor for nephrovascular hypertension. Read More

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Global research productivity and publication trends in vesicoureteral reflux: a bibliometric analysis.

Minerva Pediatr (Torino) 2021 May 5. Epub 2021 May 5.

Department of Urology, Faculty of Medicine, Hitit University, Çorum, Turkey.

Background: To make a holistic, comprehensive analysis of scientific publications on the subject of vesicoureteral reflux (VUR) between 1980 and 2019 using bibliometric methods, and by determining global research trends, to establish an important resource for future studies.

Methods: All the scientific documents were accessed which had the key word "vesicoureteral reflux" in the "Title" section in the Web of Science (WoS) database between 1980 and 2019. Using bibliometric methods, articles related to VUR (access date:20. Read More

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Antireflux endoscopic injection therapy in post-pubertal patients via techniques adopted for the dilated ureteral orifice: a retrospective single-center study.

BMC Urol 2021 Apr 24;21(1):70. Epub 2021 Apr 24.

Department of Pediatric Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.

Background: To investigate the efficacy and safety of endoscopic injection therapy for vesicoureteral reflux in post-pubertal patients with dilated ureteral orifice via modified hydrodistension implantation techniques.

Methods: We retrospectively reviewed medical records including operational procedure and clinical course of all consecutive patients over 12 years old with a history of injection therapy. Endoscopic injection of dextranomer/hyaluronic acid copolymer was performed under hydrodistension implantation technique with some modifications in order to inject through dilated ureteral orifice align with the intramural ureter. Read More

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Contrast-enhanced voiding urosonography for the diagnosis of vesicoureteral reflux and intrarenal reflux: a comparison of diagnostic performance with fluoroscopic voiding cystourethrography.

Ultrasonography 2021 Feb 10. Epub 2021 Feb 10.

Department of Radiology, Seoul National University Hospital, Seoul, Korea.

Purpose: This study evaluated the diagnostic performance of contrast-enhanced voiding urosonography (ce-VUS) using a second-generation ultrasound contrast agent for the diagnosis of vesicoureteral reflux (VUR) and intrarenal reflux (IRR), and compared it with that of standard fluoroscopic voiding cystourethrography (VCUG).

Methods: Thirty-two consecutive children from April to September 2019 were included in this study. ce-VUS and VCUG were performed simultaneously by two operators with intravesical infusion of a mixture of ultrasound contrast medium, iodinated contrast medium and water. Read More

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February 2021

Management of Vesicoureteral Reflux: What Have We Learned Over the Last 20 Years?

Front Pediatr 2021 31;9:650326. Epub 2021 Mar 31.

Pediatric Urology, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA, United States.

Vesicoureteral reflux (VUR) is associated with increased risks of urinary tract infection, renal scarring and reflux nephropathy. We review advancements over the last two decades in our understanding and management of VUR. Over time, the condition may resolve spontaneously but it can persist for many years and bladder/bowel dysfunction is often involved. Read More

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Renal Transplant Hydroureteronephrosis as a Manifestation of Rejection: An Under-Recognized Entity?

Case Rep Nephrol Dial 2021 Jan-Apr;11(1):87-94. Epub 2021 Mar 15.

Division of Pediatric Nephrology, Department of Pediatrics, University of Florida, Gainesville, Florida, USA.

Hydroureteronephrosis (HUN) of the renal transplant (RT) can be obstructive or non-obstructive, refluxing or non-refluxing, and can cause allograft dysfunction. HUN of the RT as a manifestation of rejection is uncommon and has not been described in children. We describe two pediatric RT recipients who presented with late-onset HUN, 5 and 10 years after transplantation. Read More

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Antegrade endoscopic dilatation as an alternative approach to primary obstructive megaureter.

Cir Pediatr 2021 Apr 1;34(2):100-104. Epub 2021 Apr 1.

Interventional Radiology Department. La Paz University Hospital. Madrid (Spain).

Objectives: Congenital primary obstructive megaureter (POM) is caused by ureterovesical junction stenosis, reduced peristalsis, and the resulting dilatation. Even though ureteral re-implantation remains the current gold standard technique, retrograde dilatation is considered as an effective therapeutic alternative with good results and growing proponents - to the extent it has become the technique of choice in some healthcare facilities. The objective was to present an alternative approach for treatment purposes. Read More

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[The opportunities of pneumovesicoscopic approach for correction of disorders of vesicoureteral junction in children].

Urologiia 2021 Mar(1):95-102

N.A. Lopatkin Research Institute of Urology and Interventional Radiology branch of the National Medical Research Radiological Center, Moscow, Russia.

Background: pneumovesicoscopic approach gives new possibilities for endovideosurgical correction of congenital ureteral and bladder pathology.

Aim: To increase the efficiency of ureteral reimplantation in patients with vesicoureteral reflux (VUR), obstructive megaureter and bladder pathology by using pneumovesicoscopic access.

Materials And Methods: For the period 2014 - 2020 a total of 52 children aged from 10 months up to 15 years (median 2. Read More

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Routine evaluation of vesico-ureteric reflux in children with anorectal malformation does not reduce the rate of urinary tract infection.

J Pediatr Surg 2021 Mar 5. Epub 2021 Mar 5.

Alder Hey Children's Hospital, East Prescot Rd, Liverpool, United Kingdom.

Objective: Children with anorectal malformations (ARM) have a high rate of renal anomalies and increased risk of urinary tract infection (UTI). We aimed to determine whether using routine Micturating Cystourethrogram (MCUG) to detect VUR is effective in reducing the incidence of UTI or renal scarring in children with ARM.

Methods: A retrospective study of consecutive children diagnosed with ARM in two centres with a minimum of 3 years follow-up was performed, excluding those with cloaca or an MCUG prior to ARM repair. Read More

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Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation.

Pediatr Radiol 2021 Mar 31. Epub 2021 Mar 31.

Pediatric Ultrasound Center, Thessaloniki, Greece.

Contrast-enhanced voiding urosonography (ceVUS) is a well-established, sensitive and safe ultrasound (US) modality for detecting and grading vesicoureteral reflux (VUR) and urethral imaging in children. Nearly three decades of remarkable advances in US technology and US contrast agents have refined ceVUS's diagnostic potential. The recent approval of Lumason/SonoVue in the United States, Europe and China for pediatric intravesical applications marked the beginning of a new era for this type of contrast US imaging. Read More

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Evaluation of ventilator associated events in critically ill patients with invasive mechanical ventilation: A prospective cohort study at a resource limited setting in Northern India.

J Crit Care 2021 Mar 6;64:29-35. Epub 2021 Mar 6.

Department of Critical Care Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.

Purpose: The primary aim of this study was to identify the modifiable risk factors for acquiring ventilator associated events (VAE). Secondary aims were to investigate the intensive care unit (ICU) course and impact of VAE on patient outcome.

Methods: This prospective, observational single center cohort study included 247 patients on mechanical ventilation for 4 calendar days at a 20-bed ICU between January 2018-June 2019. Read More

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Risk factors for kidney scarring and vesicoureteral reflux in 421 children after their first acute pyelonephritis, and appraisal of international guidelines.

Pediatr Nephrol 2021 Mar 23. Epub 2021 Mar 23.

Department of Pediatric and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.

Background: Acute pyelonephritis (AP) is a common bacterial infection in childhood. Follow-up guidelines on these children are controversial. This study aimed to identify risk factors for kidney scarring and vesicoureteral reflux (VUR). Read More

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Correlation of anorectal malformation complexity and associated urologic abnormalities.

J Pediatr Surg 2021 Feb 25. Epub 2021 Feb 25.

Center for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States.

Background: Patients with anorectal malformations (ARM) commonly have associated urologic anomalies. Few large studies exist to accurately characterize the incidence or associations between severity of malformation and urologic diagnosis. The purpose of our study was to determine the incidence of urologic diagnoses in a large cohort of children with ARM and evaluate for any correlation between severity of ARM and the incidence and number of associated urologic diagnoses. Read More

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February 2021

Comparison of Subureteral Endoscopic Injection of Dextranomer/Hyaluronic Acid and Lich-Gregoir Ureteral Reimplantation in the Treatment of Pediatric Primary Vesicoureteral Reflux: A Prospective Randomized Study.

J Laparoendosc Adv Surg Tech A 2021 Mar 22. Epub 2021 Mar 22.

Department of Urology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

The gold standard of surgical intervention of vesicoureteral reflux (VUR) is open ureteral reimplantation with high success and low complication rates. However, in recent years, endoscopic injection, dextranomer/hyaluronic acid (Dx/HA), has become an effective therapy for VUR. It is noted that limited prospective randomized trials compare the different surgical techniques of especially endoscopic injection versus open procedures. Read More

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Intrarenal Reflux in the Light of Contrast-Enhanced Voiding Urosonography.

Front Pediatr 2021 2;9:642077. Epub 2021 Mar 2.

University Hospital Split, Split, Croatia.

The aim of this study was to analyze the incidence of intrarenal reflux (IRR) among vesicoureteral refluxes (VURs), diagnosed by contrast-enhanced voiding urosonography (ceVUS), to define VURs which are positive to IRR and their locations in the kidney. Seventy patients with VURs, including 103 uretero-renal units (URUs) with VURs of grades II-V (37 URUs were excluded because of renal anomalies or absence of VUR) were examined with ceVUS due to recurrent febrile UTI or first febrile UTI accompanied by abnormalities on renal ultrasonography. Patients were examined on GE Logiq S8 ultrasound machine, using second generation of ultrasound contrast agent. Read More

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Case report: The theory of post-ileocystoplasty spherical configuration in patients with low-capacity bladder.

Int J Surg Case Rep 2021 Apr 5;81:105731. Epub 2021 Mar 5.

Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara - Haji Adam Malik General Hospital Medan, Jl. Bunga Lau No.17, Kemenangan Tani, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara, 20136, Indonesia. Electronic address:

Introduction: Bladder augmentation can be performed by detubularization of the small or large intestine. A large capacity bladder is necessary to avoid frequent urination; thus, the ileal sac must be able to store the maximum volume of urine with relatively low pressure and the shortest length of the intestine. The acceptable pressure capacity should always be under ureteric pressure to avoid back pressure and kidney damage. Read More

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Incidental discovery of endourethral clip migration 10 years after radical prostatectomy: A case report and review of the literature.

Urologia 2021 Mar 10:3915603211001177. Epub 2021 Mar 10.

First Department of Urology, "G. Gennimatas" General Hospital, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki, Greece.

Introduction: Surgical clips (SCs) have been widely used for a variety of surgical procedures over the years. Despite their advantages and proven effectiveness, several clip-related complications have been reported, creating dilemmas as to their optimal use.

Case Description: Herein, we present a rare delayed and incidental discovery of two endourethral metallic SCs in a 77-year-old male seeking treatment for acute renal colic. Read More

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Factors predicting the success of intradetrusor onabotulinum toxin-A treatment in children with neurogenic bladders due to myelomeningocele: The outcomes of a large cohort.

J Pediatr Urol 2021 Feb 23. Epub 2021 Feb 23.

Department of Urology, Biruni University, Istanbul, Turkey. Electronic address:

Objective: This study aimed to determine the effectiveness of intradetrusor injections of onabotulinum toxin-A (BoNT-A) in pediatric patients with neurogenic bladders (NB) due to myelomeningocele (MMC). The factors predicting success were also evaluated.

Study Design: We retrospectively identified 62 patients with NB due to MMC who underwent intravesical BoNT-A injection (100-300 U) between May 2013 and December 2018. Read More

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February 2021

Expression of Low Affinity Nerve Growth Factor Receptor p75 in Classic Bladder Exstrophy.

Front Pediatr 2021 22;9:634343. Epub 2021 Feb 22.

Department of Pediatric Urology, Clinic St. Hedwig, University of Regensburg, Regensburg, Germany.

Successful primary closure of classic bladder exstrophy (BE) is crucial for development of bladder capacity and voided continence. It is universally agreed that an intensive pain management including the use of caudal epidural anesthesia is an essential cornerstone for the outcome of this complex surgery. Whether and to what extent pain is caused by structural or functional changes is not yet known. Read More

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February 2021

[Clinical features of neurogenic bladder with vesicoureteral reflux in children].

Zhongguo Dang Dai Er Ke Za Zhi 2021 Mar;23(3):279-282

Department of Nephrology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.

Objective: To study the clinical features of vesicoureteral reflux (VUR) in children with neurogenic bladder (NB), and to provide a reference for its early diagnosis and treatment.

Methods: Clinical data were collected from 26 children with NB and urinary tract infection who were admitted to the Department of Pediatric Nephrology from January 2014 to December 2019. According to the presence or absence of VUR, the children were divided into a VUR group with 11 children and a non-VUR group with 15 children. Read More

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Types of Parenchymal Changes Diagnosed on DMSA Scans of Kidneys Affected by Different Grades of Vesicoureteral Reflux.

Med Sci Monit 2021 Mar 1;27:e929617. Epub 2021 Mar 1.

Department of Pediatrics, University Hospital in Split, Split, Croatia.

BACKGROUND Renal parenchymal damage and scarring usually is associated with urinary tract infection (UTI), whereas the impact of vesicoureteral reflux (VUR) on the kidneys is unclear. We aimed to compare kidneys with all grades of VUR (grades Io-V) and those without VUR by using direct radionuclide cystography, voiding cystourethrography, and findings from 99mTc-DMSA scintigraphy (DMSA scan). MATERIAL AND METHODS The present analysis included 253 renal ureteral units (RUU) from 129 children with VUR and recurrent UTI and children with a single febrile UTI associated with abnormal ultrasonographic findings. Read More

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Urinary tract imaging in infants with spina bifida: a selective approach to a baseline DMSA.

J Pediatr Urol 2021 Feb 11. Epub 2021 Feb 11.

School of Mathematics and Statistics, Ireland; University College Dublin, Ireland.

Introduction: There is no general agreement among paediatric urologists on how infants with spina bifida (SB) should be investigated after birth. Recently the EUA/ESPU guidelines have been published recommending a baseline DMSA scan in the first year of life and a Voiding Cystourethrogram (VCUG) or Videourodynamic (VUD) between the second and third month of life.

Objective: The aim of this study was to evaluate the outcome of renal investigations in the first year of life in infants with SB to verify if an early DMSA scan is indicated in the management of this group of patients. Read More

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February 2021

Ureteral reimplantation aligned laparoscopically: Pneumovesicoscopic Politano-Leadbetter reimplantation in children.

J Pediatr Urol 2021 Feb 16. Epub 2021 Feb 16.

Ondokuz Mayıs University, School of Medicine, Department of Pediatric Surgery, Ondokuz Mayıs Üniversitesi Kurupelit Kampüsü, Atakum, Samsun, 55270, Turkey. Electronic address:

Introduction: Ureteroneocsytostomy is a well-established procedure for correction of certain ureterovesical conditions like vesicoureteral reflux and ureterevesical obstruction. Amazing developments in technology paved the way for minimally invasive surgery and conventional procedures are increasingly being performed minimal invasively during the recent decades. Although Politano-Leadbetter ureteroneocystostomy is an anatomical repair, lost its popularity against Cohen's technique as it is more challenging to perform and requires extravesical dissection which may increase the complication rates. Read More

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February 2021

Contrast-enhanced voiding urosonography in the diagnosis of intrarenal reflux.

J Ultrasound 2021 Feb 26. Epub 2021 Feb 26.

Children's Hospital Zagreb, Ul. Vjekoslava Klaića 16, 10000, Zagreb, Croatia.

Purpose: Although contrast-enhanced urosonography (ceVUS) has shown capable diagnostic accuracy for the diagnosis of vesicoureteral reflux (VUR) in children, the ability of ceVUS to detect intrarenal reflux (IRR) is considered limited. The purpose of our study is to assess the ability of ceVUS to detect IRR as well as its association with age, gender, and the grade of VUR.

Methods: This study included 5153 children who were referred to our clinic for ceVUS. Read More

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February 2021

Iatrogenic Ureteral Injury Treatment with Biodegradable Antireflux Heparin-Coated Ureteral Stent-Animal Model Comparative Study.

J Endourol 2021 Apr 26. Epub 2021 Apr 26.

Scientific Direction, Jesús Usón Minimally Invasive Surgery Centre, Cáceres, Spain.

The aim is to assess the effectiveness of a biodegradable antireflux ureteral stent with heparin coating in a comparative study (BraidStent-H) in an animal model for the treatment of iatrogenic ureteral perforation. A total of 24 female pigs underwent initial endoscopic, nephrosonographic, and contrast fluoroscopy assessment of the urinary tract. Afterward, unilateral iatrogenic perforation in proximal ureter model was performed. Read More

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Three different laparoscopic techniques for the management of iatrogenic ureteral injury: A multi-institutional study with medium-term outcomes.

Asian J Surg 2021 Feb 16. Epub 2021 Feb 16.

Department of Urology, Dong-a University Hospital, Busan, South Korea. Electronic address:

Background: Excellent success rates with short-term outcomes are noted for laparoscopic ureteral reconstruction (LUR) for iatrogenic ureteral injury. This multi-institutional study assessed the medium-term (>1 year) outcomes and compared three surgical techniques of LUR.

Methods: Patients who underwent LUR at five tertiary hospitals between January 2007 and June 2016 were retrospectively analyzed. Read More

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February 2021

Prevalence of high-risk bladder categorization with prenatal and postnatal myelomeningocele repair types.

Neurourol Urodyn 2021 03 19;40(3):829-839. Epub 2021 Feb 19.

Division of Urology, Department of Surgery, Texas Children's Hospital, Houston, Texas, USA.

Introduction: Urologic substudies of prenatal myelomeningocele (MMC) closure have focused primarily on continence without significant clinical benefit. Fetoscopic MMC repair (FMR) is a newer form of prenatal intervention and touts added benefits to the mother, but urological outcomes have yet to be analyzed. We set out to focus on bladder safety rather than continence and examined bladder outcomes with different prenatal MMC repairs (FMR and prenatal open [POMR]) and compared bladder-risk-categorization to traditional postnatal repair (PSTNR). Read More

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Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux.

J Am Soc Nephrol 2021 Feb 17. Epub 2021 Feb 17.

Department of Clinical Genetics, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

Background: Vesicoureteral reflux (VUR) is a common, familial genitourinary disorder, and a major cause of pediatric urinary tract infection (UTI) and kidney failure. The genetic basis of VUR is not well understood.

Methods: A diagnostic analysis sought rare, pathogenic copy number variant (CNV) disorders among 1737 patients with VUR. Read More

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February 2021