Radiology 2020 Jun 14;295(3):640-648. Epub 2020 Apr 14.
From the Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, McGovern Medical School, 6431 Fannin St, MSB 2.100 Houston, TX 77030 (L.A.K., K.M.H., R.F.R.); Cardiovascular and Vision Laboratory, NASA Johnson Space Center, Houston, Tex (M.B.S.); Kellogg Brown & Root (KBR), Houston, Tex (A.S., S.S.L., K.M., B.R.M.); Department of Teleoncology, Memorial Sloan-Kettering Cancer Center, New York, NY (C.O.); and School of Nursing, University of Michigan, Ann Arbor, Mich (R.J.P.S.).
Background Astronauts on long-duration spaceflight missions may develop changes in ocular structure and function, which can persist for years after the return to normal gravity. Chronic exposure to elevated intracranial pressure during spaceflight is hypothesized to be a contributing factor, however, the etiologic causes remain unknown. Purpose To investigate the intracranial effects of microgravity by measuring combined changes in intracranial volumetric parameters, pituitary morphologic structure, and aqueductal cerebrospinal fluid (CSF) hydrodynamics relative to spaceflight and to establish a comprehensive model of recovery after return to Earth. Read More