434,891 results match your criteria vitamin vitamin

Ionic Hydrogels Based Wearable Sensors to Monitor the Solar Radiation Dose for Vitamin D Production and Sunburn Prevention.

ACS Appl Mater Interfaces 2021 Sep 15. Epub 2021 Sep 15.

Key Laboratory of Advanced Textile Materials & Manufacturing Technology, Ministry of Education, Zhejiang Sci-Tech University, 928 Second Avenue, 310018 Hangzhou, China.

Wearable solar radiation sensors based on ionic hydrogels are facilely prepared to simultaneously monitor the radiation dose for the production of vitamin D and the prevention of sunburn. Tetramethylethylenediamine (TEMED) is neutralized with acrylic acid (AA) to obtain tetramethylethylenediamine acrylate (TEMEDA), which is further polymerized with acrylamide by a free radical reaction. By simply adding MB or NR during the polymerization, the final obtained ionic hydrogels can indicate solar radiation. Read More

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September 2021

Characterization of Tattoo Aftercare Products: Allergenic Ingredients and Marketing Claims.

Dermatitis 2021 Sep-Oct 01;32(5):301-307

University of Minnesota Medical School.

Background: Common recommendations for tattoo aftercare to ensure proper healing include application of topical products. Little is known about tattoo aftercare products.

Methods: Tattoo aftercare products were identified from a previous study and a search on Amazon. Read More

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September 2021

Assessment of biochemical compounds and antioxidant enzyme activity in barley and wheatgrass under water deficit condition.

J Sci Food Agric 2021 Sep 15. Epub 2021 Sep 15.

Department of Food Science and Biotechnology, Gachon University, Seongnam, 13120, Republic of Korea.

Background: Wheatgrass and barley grass are freshly sprouted leaves of wheat and barley seeds and are rich sources of phytochemicals. This study was conducted to investigate the effects of drought stress on the biochemical compounds and antioxidant activities of barley and wheatgrass extracts. The grass was cultivated in the organic soil growing medium with different drought stress, mainly control with 100% water holding capacity (WHC), mild drought-stress with 75% WHC, moderate drought-stress with 50% WHC, and severe drought stress with 25% WHC in a growth chamber by controlling temperature (20/15 °C, day/night), light (12/12 h, light/dark; intensity 150 μmol m s with quantum dot light-emitting diodes), and relative humidity (60%) for 7-days. Read More

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September 2021

Hyperparathyroidism in patients with overt and mild primary aldosteronism.

Hormones (Athens) 2021 Sep 15. Epub 2021 Sep 15.

Unit of Endocrinology and Diabetes Centre, General Hospital of Athens "G Gennimatas", 154 Mesogeion Avenue, 11527, Athens, Greece.

Introduction: Increased prevalence of hyperparathyroidism (HP) has been observed in primary aldosteronism (PA) patients. However, HP prevalence in milder forms of PA has not to date been evaluated.

Objectives: The objectives of this study were to assess the prevalence of primary and secondary HP in overt and milder misdiagnosed cases of PA and to investigate the effect of treatment on parathormone (PTH) secretion. Read More

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September 2021

Contemporary management of patients with atrial fibrillation in the Netherlands and Belgium: a report from the EORP-AF long-term general registry.

Neth Heart J 2021 Sep 15. Epub 2021 Sep 15.

Arlon and Clinique Ste Thérèse, Department of Cardiology, Cliniques du Sud-Luxembourg, Bastogne, Belgium.

Background: Contemporary data regarding the characteristics, treatment and outcomes of patients with atrial fibrillation (AF) are needed. We aimed to assess these data and guideline adherence in the EURObservational Research Programme on Atrial Fibrillation (EORP-AF) long-term general registry.

Methods: We analysed 967 patients from the EORP-AF long-term general registry included in the Netherlands and Belgium from 2013 to 2016. Read More

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September 2021

[Switching from acenocoumarol to phenprocoumon: step in personalised anticoagulation?]

Ned Tijdschr Geneeskd 2021 Sep 9;165. Epub 2021 Sep 9.

UMC Groningen, afd. Hematologie, Groningen.

Acenocoumarol and phenprocoumon are vitamin K antagonists (VKA) with average half-lives of 11 hours and 160 hours, respectively. They are used to treat and prevent thrombosis in mechanical cardiac valve replacement, atrial fibrillation and venous thromboembolism. There are historical regional differences in preferred VKA in the Netherlands. Read More

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September 2021

Using a low-molecular weight heparin-calibrated anti-factor Xa assay to assess the concentration of apixaban and rivaroxaban.

Int J Lab Hematol 2021 Sep 15. Epub 2021 Sep 15.

Department of Molecular Medicine and Surgery, Karolinska Institutet & Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden.

Introduction: Direct oral anticoagulant (DOAC)-inhibiting factor Xa (FXa-DOAC) are being increasingly used as prophylaxis of venous thromboembolism and for prevention of stroke in patients with atrial fibrillation. In contrast to vitamin K antagonists, DOACs do not require monitoring in general. However, it is sometimes of value in the acute setting, for instance when considering a reversal agent in uncontrolled bleeding in patients on DOAC. Read More

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September 2021

Nutrition in Nepal: Three decades of commitment to children and women.

Matern Child Nutr 2021 Sep 15:e13229. Epub 2021 Sep 15.

Programme Division, United Nations Children's Fund (UNICEF), New York, New York, USA.

South Asia has made significant progress in reducing child undernutrition. The prevalence of stunting declined by one third between 2000 and 2019; as a result, in 2019, there were 34 million fewer stunted children than in 2000, indicating that progress for child nutrition is possible and is happening at scale. However, no country in South Asia is on track for all nutrition targets of Sustainable Development Goal 2, and the region has the highest prevalence of stunting (33. Read More

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September 2021

Corroles: The Hitherto Elusive Parent Macrocycle and its Metal Complexes.

Angew Chem Int Ed Engl 2021 Sep 15. Epub 2021 Sep 15.

Technion Israel Institute of Technology, Chemistry, ISRAEL.

The science and technology of corroles, macrocycles that owe their name to the cobalt-chelating prosthetic group of Vitamin B12 and share numerous features with the iron-chelating porphyrin present in heme proteins/enzymes, constantly crosses new boundaries ever since stable derivatives became easily accessible. Particularly important is the increasing utilization of corroles and the corresponding metal complexes for the benefit of mankind, in terms of new drug candidates for treating various diseases and as catalysts for sustainable energy relevant processes. One still unmet challenge is to gain access to the plain macrocycle, as to allow for a full elucidation of the most fundamental properties of corroles. Read More

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September 2021

Nutrient Patterns are Associated with Discordant Apolipoprotein B and Low-Density Lipoproteins: A Population-Based Analysis.

Br J Nutr 2021 Sep 15:1-21. Epub 2021 Sep 15.

School of Sports and Exercise Sciences, Faculty of Science, Liverpool John Moores University, IM Marsh Campus, Barkhill Road, Liverpool L17 6AF, United Kingdom.

Individuals with discordantly high ApoB to LDL-C levels carry a higher risk of atherosclerotic cardiovascular disease compared to those with average or discordantly low ApoB to LDL-C. We aimed to determine associations between ApoB and LDL-C discordance in relation to nutrient patterns (NPs) using National Health and Nutrition Examination Survey data. Participants were grouped by established LDL-C and ApoB cut-offs (Group 1: Low ApoB/Low LDL-C, Group 2: Low ApoB/High LDL-C, Group 3: High ApoB/Low LDL-C, Group 4: High ApoB/High LDL-C). Read More

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September 2021

Causal risk and protective factors in rheumatoid arthritis: A genetic update.

J Transl Autoimmun 2021 3;4:100119. Epub 2021 Sep 3.

Central Research Laboratory, Kazan State Medical Academy, Kazan, Russia.

The characterization of risk and protective factors in complex diseases such as rheumatoid arthritis (RA) has evolved from epidemiological studies, which test association, to the use of Mendelian randomization approaches, which test direct relationships. Indeed, direct associations with the mucosal origin of RA are retrieved with periodontal disease ( and predominantly), interstitial lung involvement, tobacco smoking and air pollutants. Next, factors directly associated with an acquired immune response include genetic factors (HLA DRB1, PTPN22), capacity to produce anti-modified protein antibodies (AMPA), and relatives with a history of autoimmune diseases. Read More

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September 2021

Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™.

Heliyon 2021 Sep 30;7(9):e07888. Epub 2021 Aug 30.

Phytor Lab for Drug Development, Hadassah Medical Center Hebrew University Biotechnology Park (JBP), Ein Kerem Campus, Jerusalem 91120, Israel.

Hair loss and predominantly female hair loss is a common dermatologic condition with serious psychosocial consequences. Effective treatments remain scarce mainly due to the multifactorial elements involved in the onset of this chronic condition. The approved drugs available are based on molecules designed towards a single pharmacological target and do not interact with the various biochemical mechanisms involved in alopecia. Read More

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September 2021

A Case of Severe Hypocalcemia Caused by Malabsorption Due to Partial Gastrectomy and Small Bowel Resection.

AACE Clin Case Rep 2021 Sep-Oct;7(5):323-326. Epub 2021 Apr 16.

Division of Endocrinology, Metabolism, and Lipids, Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia.

Objective: Calcium is an essential mineral involved in the functioning of nearly every human cell. Calcium levels are regulated by dietary absorption, vitamin D status, and parathyroid hormone (PTH). This report describes a patient in whom childhood bowel resection and partial gastrectomy resulted in malabsorptive hypocalcemia in adulthood. Read More

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A simple and sensitive method to detect vitamin D receptor expression in various disease models using stool samples.

Genes Dis 2021 Nov 17;8(6):939-945. Epub 2020 Mar 17.

Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

Vitamin D receptor (VDR) executes the main biological functions of its ligand vitamin D. VDR/vitamin D plays critical roles in regulating host immunity, maintaining barrier functions, and shaping gut microbiome. Reduction of intestinal VDR has been reported in various diseases, including inflammatory diseases and colon cancer. Read More

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November 2021

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives.

Acta Pharm Sin B 2021 Aug 29;11(8):2416-2448. Epub 2021 Apr 29.

Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastrointestinal (GI) tract and epithelia, the therapeutic PPs are usually administered by parenteral route. Given the big demand for oral administration in clinical use, a variety of researches focused on developing new technologies to overcome GI barriers of PPs, such as enteric coating, enzyme inhibitors, permeation enhancers, nanoparticles, as well as intestinal microdevices. Read More

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Pulmonary Function Testing in Patients With E-Cigarette, or Vaping, Product Use-Associated Lung Injury.

Cureus 2021 Aug 9;13(8):e17019. Epub 2021 Aug 9.

Pulmonary and Critical Care Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell/North Shore University Hospital and Long Island Jewish Medical Center, Hempstead, USA.

In 2019 there was an outbreak of respiratory illnesses amongst people who used E-cigarettes. This phenomenon was labeled 'EVALI' which stands for "Electronic cigarette (E-cigarette), or Vaping, Product Use-Associated Lung Injury" and is a life-threatening illness of the lungs associated with E-cigarette use. It is believed to be caused by certain chemicals in E-cigarette cartridges, such as vitamin E acetate, but the exact pathophysiological mechanism is yet to be elucidated. Read More

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Hyperemesis Gravidarum With Paraparesis and Tetany.

Cureus 2021 Aug 9;13(8):e17014. Epub 2021 Aug 9.

Internal Medicine, Rajah Muthiah Medical College & Hospital, Chidambaram, IND.

Subacute-onset muscle weakness can result from channelopathies, inflammatory myopathies, thyroid dysfunction, hypoparathyroidism, vitamin D deficiency, and dyselectrolytemias like hypokalemia, hypocalcemia, and hypomagnesemia. We report a curious and extremely rare case of a 29-year-old woman with hyperemesis gravidarum presenting with disabling muscle weakness involving her lower limbs and trunk, and concurrent features of tetany. Following voluminous vomiting over the last two months, she presented with history of weakness of her lower limbs of 14 days duration, resulting in difficulty in her getting out of bed or walking unassisted. Read More

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The Role of Vitamins in Non-Alcoholic Fatty Liver Disease: A Systematic Review.

Cureus 2021 Aug 3;13(8):e16855. Epub 2021 Aug 3.

Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Non-Alcoholic Fatty Liver Disease (NAFLD) emerged as the most prevalent liver disorder contributing significantly to disease burden worldwide. It manifests as a broad spectrum of hepatic damage with varying severity ranging from less serious steatosis to a more severe Non-Alcoholic Steatohepatitis (NASH), with or without fibrosis, cirrhosis, and hepatocellular carcinoma. Vitamins, on the other hand, are micronutrients that are vital for healthy well-being. Read More

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Syndrome of Inappropriate Antidiuretic Hormone Secretion and Lead Toxicity in a Child With Sickle Cell Disease and Pica.

Cureus 2021 Aug 1;13(8):e16813. Epub 2021 Aug 1.

Division of Medical Toxicology, Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Allentown, USA.

We describe the presentation and management of a three-year-old child with a history of pica, vitamin D deficiency, and sickle cell disease, who was admitted for pyelonephritis, and found to have elevated blood lead level (BLL) of 103.7 µg/dL, and who subsequently developed altered mental status and syndrome of inappropriate antidiuretic hormone secretion (SIADH). In consultation with Medical Toxicology, the patient was chelated with calcium disodium edetate (EDTA) and British Anti Lewisite (BAL). Read More

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Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with fertilization outcome: an observational pilot study.

Arch Med Sci 2021 17;17(5):1418-1422. Epub 2021 Aug 17.

Clinic for Gynaecology and Obstetrics, "Narodni front", Belgrade, Serbia.

Introduction: Follicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of fertilization (IVF) outcomes.

Methods: This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring vitamin D. Read More

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An observational and Mendelian randomisation study on vitamin D and COVID-19 risk in UK Biobank.

Sci Rep 2021 09 14;11(1):18262. Epub 2021 Sep 14.

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, Scotland, UK.

A growing body of evidence suggests that vitamin D deficiency has been associated with an increased susceptibility to viral and bacterial respiratory infections. In this study, we aimed to examine the association between vitamin D and COVID-19 risk and outcomes. We used logistic regression to identify associations between vitamin D variables and COVID-19 (risk of infection, hospitalisation and death) in 417,342 participants from UK Biobank. Read More

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September 2021

Influence of adding vitamin D3 to standard clarithromycin-based triple therapy on the eradication rates of Helicobacter pylori infection.

Arab J Gastroenterol 2021 Sep 11. Epub 2021 Sep 11.

Department of Clinical Pathology, Faculty of Medicine, AL-Azhar University, Cairo, Egypt. Electronic address:

Background And Study Aims: The successful eradication rates with standard clarithromycin-based triple therapy are declining concerning the high antibiotic resistance rate and adverse drug reactions. This study aims to evaluate the effect of adding 1,25-hydroxyvitamin D3 on the eradication rates of the standard clarithromycin-based triple therapy for Helicobacter pylori infection.

Patients And Methods: This is a randomized prospective comparative study of 150 patients diagnosed with H. Read More

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September 2021

Vitamin D deficiency and inactivated SARS-CoV-2 vaccines.

Eur J Intern Med 2021 Sep 9. Epub 2021 Sep 9.

Division of Nephrology, Department of Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan. Electronic address:

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September 2021

Vitamin D and risk of ankylosing spondylitis: A two-sample mendelian randomization study.

Hum Immunol 2021 Sep 11. Epub 2021 Sep 11.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui 230032, China. Electronic address:

Objectives: To study whether Vitamin D levels are causally associated with ankylosing spondylitis (AS).

Methods: Two-sample Mendelian randomization (TSMR) analysis was performed by employing MR-Egger regression, weighted median (WM), inverse-variance weighted (IVW), and weight mode (WM) methods. The odds ratio (OR) with 95% confidence intervals (CIs) was used to evaluate this association. Read More

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September 2021

Outbreak of oral ulcers (glossitis) among the students of three central schools under Tsirang district Bhutan, 2018.

BMC Oral Health 2021 Sep 14;21(1):444. Epub 2021 Sep 14.

Yebilaptsa Hospital, Zhemgang District, Bhutan.

Background: Nutritional deficiencies are common worldwide and is most notable in low and middle income countries. In the early weeks of September 2018, oral sores mostly affecting the tongue were reported in three central schools under Tsirang district, Bhutan. A total of 204 students were affected in the three central schools. Read More

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September 2021

An update of the efficacy and comparative characteristics of direct (new) oral anticoagulants (DOACs).

Cardiovasc Hematol Agents Med Chem 2021 Sep 13. Epub 2021 Sep 13.

Department of Emergency Medicine, Haseki Education and Research Hospital, Fatih, Istanbul. Turkey.

Direct (New-generation) Oral Anticoagulants (DOACs) have emerged as effective agents which are used in place of vitamin-K antagonists in treatment and prophylaxis of Venous Thromboembolism (VTE), atrial fibrillation and other thrombotic diseases. Among them, the FIIa-direct thrombin inhibitor dabigatran and FXa inhibitors (rivaroxaban, apixaban, edoxaban) are the most broadly used. Anticoagulant dosing may differ under special considerations. Read More

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September 2021

Improving vitamin D status in bariatric surgery subjects with monthly high-dose ergocalciferol.

Int J Vitam Nutr Res 2021 Sep 15. Epub 2021 Sep 15.

Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.

Vitamin D insufficiency is common before and after bariatric surgery. Optimal supplementation to treat vitamin D insufficiency is not clearly defined. Determine if serum 25 (OH) D levels improve by the consumption of an additional monthly ergocalciferol supplement by subjects after bariatric surgery. Read More

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September 2021

Wait-there's evidence for that? Integrative medicine treatments for major depressive disorder.

Int J Psychiatry Med 2021 Sep;56(5):334-343

Beaumont Grosse Pointe Family Medicine Residency, Grosse Pointe, MI, USA.

Depression is one of the most common mental health disorders and currently affects over 17 million Americans. Up to two-thirds of patients with depression in the United States will seek complementary and alternative or integrative medical treatments and thus medical providers who treat depression should understand that many integrative medical treatments have evidence of efficacy either as monotherapies or as add-on adjuncts to other treatments. This review references guidelines from the Canadian Network for Mood and Anxiety Treatments and Michigan Medicine, along with an updated literature review, to provide a framework for reviewing medications or herbal formulation, as well as other therapies, which have evidence in the treatment of depression. Read More

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September 2021

How Much Does Serum 25(OH)D Improve by Vitamin D Supplement and Fortified Food in Children? A Systematic Review and Meta-Analysis.

J Pediatr Gastroenterol Nutr 2021 Sep 13. Epub 2021 Sep 13.

Laboratory of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objectives: This study was conducted to respond certain important questions regarding the efficacy of vitamin D fortification and supplementation in children using a meta-analytical approach.

Methods: MEDLINE, PubMed, Embase, Cochrane Library, and Google Scholar were searched, and 2341 studies were found in a preliminary search. After screening of titles and abstracts, 31 studies were selected. Read More

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September 2021

Nutrients and Bioactive Components of Human Milk After one Year of Lactation. Implication for Human Milk Banks.

J Pediatr Gastroenterol Nutr 2021 Sep 13. Epub 2021 Sep 13.

Human Milk Bank, Ludwik Rydygier' Provincial Polyclinic Hospital in Torun, Torun, St. Jozef 53-59 St., 87-100 Torun, Poland; Department of Physiology and Toxicology, Faculty of Biological Sciences, Kazimierz Wielki University, Chodkiewicza 30 St., 85-064 Bydgoszcz, Poland; Department of Chemistry, Technology and Biotechnology of Food, Chemical Faculty, Gdansk University of Technology, Narutowicza 11/12 St. 80-233 Gdansk, Poland; Laboratory of Human Milk and Lactation Research at Regional Human Milk Bank in Holy Family Hospital; Medical University of Warsaw, The Faculty of Health Sciences, Department of Medical Biology, Litewska 16/16 St., 02-091 Warsaw, Poland; Department of Midwifery, Centre of Postgraduate Medical Education, St. Sophia's Hospital, 90 Zelazna St. 01-004 Warsaw, Poland.

Objective: Specifying the nutrient content and bioactive compounds in milk from long-term lactation for the purpose of finding additional sources of donors' milk for HMBs.

Method: Human milk samples were collected from 43 mothers of term infants (term infant human milk, TIHM) (3-6 weeks of lactation) and 50 mothers who have breastfed for over a year (long-nursing human milk, LNHM). The milk collection time was 24 hours. Read More

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September 2021