AIDS 2021 Jun 10. Epub 2021 Jun 10.
KEMRI Wellcome Trust Research Programme, Kilifi, Kenya Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg South Africa Africa Health Research Institute, Durban, South Africa HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa Max Planck Institute for Infection Biology, Berlin, Germany Division of Infection and Immunity, University College London, London, UK Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Objectives: Antibody function has been extensively studied in HIV infected adults but is relatively understudied in children. Emerging data suggests enhanced development of broadly neutralizing antibodies (bNAbs) in children, but Fc effector functions in this group are less well-defined. Here, we profiled overall antibody function in HIV infected children. Read More