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Yoga for chronic chemotherapy-induced peripheral neuropathy pain: a pilot, randomized controlled trial.

J Cancer Surviv 2021 Sep 15. Epub 2021 Sep 15.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Purpose: To determine the feasibility of implementing a yoga intervention for cancer survivors with chronic CIPN pain, as well as the impact of the intervention on patient-reported outcomes.

Methods: Cancer survivors with chronic CIPN pain were recruited from the breast, gastrointestinal, and gynecological oncology centers at Dana-Farber Cancer Institute. Participants were randomized (2:1) to receive an 8-week yoga intervention or usual care. Read More

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September 2021

[Benefit assessment of digital health applications-challenges and opportunities].

Authors:
Lars G Hemkens

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2021 Sep 15. Epub 2021 Sep 15.

Basel Institute for Clinical Epidemiology and Biostatistics (ceb), Department of Clinical Research, University Hospital Basel, Spitalstrasse 12, 4031, Basel, Schweiz.

Digital health applications promise to improve patient health and medical care. This analysis provides a brief overview of evidence-based benefit assessment and the challenges to the underlying evidence as prerequisites for optimal patient-oriented decision making. Classical concepts in study design, recent developments, and innovative approaches are described with the aim of highlighting future areas of development in innovative study designs and strategic evaluation concepts for digital health applications. Read More

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September 2021

Ecological implications beyond the ecotoxicity of plastic debris on marine phytoplankton assemblage structure and functioning.

Environ Pollut 2021 Sep 3;290:118101. Epub 2021 Sep 3.

Department of Biomolecular Sciences, University of Urbino, Campus E. Mattei, 61121, Urbino, Italy; CoNISMa, National Inter-University Consortium for Marine Sciences, 00196, Rome, Italy; Fano Marine Center, The Inter-Institute Center for Research on Marine Biodiversity, Resources and Biotechnologies, 61032, Fano, Italy.

Plastic pollution is a global issue posing a threat to marine biota with ecological implications on ecosystem functioning. Micro and nanoplastic impact on phytoplankton autotrophic species (e.g. Read More

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September 2021

Human cortical dynamics during full-body heading changes.

Sci Rep 2021 Sep 14;11(1):18186. Epub 2021 Sep 14.

Institute of Psychology and Ergonomics, Technische Universität Berlin, Berlin, Germany.

The retrosplenial complex (RSC) plays a crucial role in spatial orientation by computing heading direction and translating between distinct spatial reference frames based on multi-sensory information. While invasive studies allow investigating heading computation in moving animals, established non-invasive analyses of human brain dynamics are restricted to stationary setups. To investigate the role of the RSC in heading computation of actively moving humans, we used a Mobile Brain/Body Imaging approach synchronizing electroencephalography with motion capture and virtual reality. Read More

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September 2021

Development of a culturally and linguistically sensitive virtual reality educational platform to improve vaccine acceptance within a refugee population: the SHIFA community engagement-public health innovation programme.

BMJ Open 2021 Sep 14;11(9):e051184. Epub 2021 Sep 14.

Healthcare Innovation and Practice Transformation Laboratory, Scripps Clinic La Jolla-Genesee Executive Plaza, San Diego, California, USA.

Objectives: To combat misinformation, engender trust and increase health literacy, we developed a culturally and linguistically appropriate virtual reality (VR) vaccination education platform using community-engaged approaches within a Somali refugee community.

Design: Community-based participatory research (CBPR) methods including focus group discussions, interviews, and surveys were conducted with Somali community members and expert advisors to design the educational content. Co-design approaches with community input were employed in a phased approach to develop the VR storyline. Read More

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September 2021

Three-dimensional stochastic numerical breast phantoms for enabling virtual imaging trials of ultrasound computed tomography.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 Sep 14;PP. Epub 2021 Sep 14.

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials, provide researchers with an economical and convenient route to systematically explore imaging system designs and image reconstruction methods. When simulating an imaging technology intended for clinical use, it is essential to employ realistic numerical phantoms that can facilitate the objective, or task-based, assessment of image quality. Read More

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September 2021

Computed tomography imaging superimposition protocols to assess outcomes in orthognathic surgery: a systematic review with comprehensive recommendations.

Dentomaxillofac Radiol 2021 Sep 14:20210340. Epub 2021 Sep 14.

Division of Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium.

Objectives: A systematic review was performed to analyze the current evidence on three-dimensional (3D) computed tomography (CT) superimposition protocols used to assess dentomaxillofacial changes after orthognathic and orthofacial surgery. Accuracy, reproducibility, and efficiency were evaluated.

Methods: The search was divided into Main Search (PubMed, EMBASE, Cochrane Library, LILACS, and SciELO), Grey Literature search (Google Scholar and Open Grey), and Manual search. Read More

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September 2021

Integration of imaging modalities in digital dental workflows - possibilities, limitations, and potential future developments.

Dentomaxillofac Radiol 2021 Sep 14:20210268. Epub 2021 Sep 14.

Department of Imaging & Pathology, Faculty of Medicine, KU Leuven & Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium.

The digital workflow process follows different steps for all dental specialties. However, the main ingredient for the diagnosis, treatment planning and follow-up workflow recipes is the imaging chain. The steps in the imaging chain usually include all or at least some of the following modalities: cone-beam computed tomographic data acquisition, segmentation of the cone-beam computed tomography image, intraoral scanning, facial three-dimensional soft tissue capture and superimposition of all the images for the creation of a virtual augmented model. Read More

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September 2021

The Impact of COVID-19 on Patients With Cancer: A National Study of Patient Experiences.

Am J Clin Oncol 2021 Sep 14. Epub 2021 Sep 14.

Division of Oncology, Department of Medicine Center for Population Health Sciences, Stanford University, Stanford Veterans Affairs Palo Alto Health Care System, Palo Alto, CA.

Objectives: The coronavirus disease 2019 (COVID-19) pandemic abruptly disrupted cancer care. The impact of these disruptions on patient experiences remain relatively understudied. The objective of this study was to assess patients' perspectives regarding the impact of COVID-19 on their experiences, including their cancer care, emotional and mental health, and social determinants of health, and to evaluate whether these outcomes differed by cancer stage. Read More

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September 2021

Promoting Physical Activity Through Conversational Agents: Mixed Methods Systematic Review.

J Med Internet Res 2021 Sep 14;23(9):e25486. Epub 2021 Sep 14.

School of Social Welfare, University of California, Berkeley, Berkeley, CA, United States.

Background: Regular physical activity (PA) is crucial for well-being; however, healthy habits are difficult to create and maintain. Interventions delivered via conversational agents (eg, chatbots or virtual agents) are a novel and potentially accessible way to promote PA. Thus, it is important to understand the evolving landscape of research that uses conversational agents. Read More

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September 2021

"It Takes Some Empathy, Sympathy, and Listening": Telephone Outreach to Older Detroiters in a Pandemic as a Modality to Gain an Understanding of Challenges and Resiliency.

J Urban Health 2021 Sep 13. Epub 2021 Sep 13.

School of Social Work, University of Michigan, Ann Arbor, USA.

This manuscript describes a telephone outreach project for members of a research registry program for older adults in Detroit, Michigan. From April until December 2020, the Healthier Black Elders Center designed and implemented a telephone outreach program, calling 1204 older adults utilizing 15 staff and volunteers. The calls served to check in on registry members and collect data on mental health, coping mechanisms, access to services, masks, testing, and tele-health. Read More

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September 2021

Clinical pharmacy specialists providing consistent comprehensive medication management with increased efficiency through telemedicine during the COVID19 pandemic.

J Am Coll Clin Pharm 2021 Aug 11;4(8):934-938. Epub 2021 Jul 11.

Tennessee Valley Healthcare System, Veterans Affairs Alvin C. York Campus Murfreesboro Tennessee USA.

Introduction: The Veterans Affairs (VA) has been at the forefront of harnessing the skills of clinical pharmacy specialists (CPS) in patient-aligned care teams (PACT) to improve patient care outcomes and create access for veterans. With the unfortunate arrival of Coronavirus disease 2019 (COVID19), PACT CPS were duty-bound to expand telehealth services at an accelerated rate. The purpose of this quality improvement analysis is to compare CPS efficiency as well as some objective patient metrics to assess for a change in the quality of care. Read More

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Temporal Profile of Pneumonia After Stroke.

Stroke 2021 Sep 14:STROKEAHA120032787. Epub 2021 Sep 14.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands (J.C.d.J., H.B.v.d.W.).

Background And Purpose: The occurrence of pneumonia after stroke is associated with a higher risk of poor outcome or death. We assessed the temporal profile of pneumonia after stroke and its association with poor outcome at several time points to identify the most optimal period for testing pneumonia prevention strategies.

Methods: We analyzed individual patient data stored in the VISTA (Virtual International Stroke Trials Archive) from randomized acute stroke trials with an inclusion window up to 24 hours after stroke onset and assessed the occurrence of pneumonia in the first 90 days after stroke. Read More

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September 2021

Modeling of an irrigation system in a virtual physical space.

Math Biosci Eng 2021 Aug;18(5):6841-6856

Plovdiv University "Paisii Hilendarski", Plovdiv 4000, Bulgaria.

One of the major challenges that smart agriculture is expected to address is the efficient use of water resources. The conservation and the efficient use of clean water is a long-term strategy worldwide. Modeling of smart agriculture systems is an important factor because the processes there are very slow and sometimes it takes a year or more for a full crop cycle. Read More

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Empowering Women as Leaders in Pediatric Anesthesiology: Methodology, Lessons, and Early Outcomes of a National Initiative.

Anesth Analg 2021 Sep 13. Epub 2021 Sep 13.

Division of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC.

Research has shown that women have leadership ability equal to or better than that of their male counterparts, yet proportionally fewer women than men achieve leadership positions and promotion in medicine. The Women's Empowerment and Leadership Initiative (WELI) was founded within the Society for Pediatric Anesthesia (SPA) in 2018 as a multidimensional program to help address the significant career development, leadership, and promotion gender gap between men and women in anesthesiology. Herein, we describe WELI's development and implementation with an early assessment of effectiveness at 2 years. Read More

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September 2021

A novel digital technique for maintaining maxillomandibular relations in fixed prosthetic rehabilitations.

J Dent 2021 Sep 10:103798. Epub 2021 Sep 10.

Research fellow and clinical lecturer, Department of Clinical and Experimental Medicine, University of Foggia School of Dentistry, Foggia, Italy. Electronic address:

Introduction: In fixed prosthetic rehabilitations, the restorations must be designed and fabricated in a proper maxillomandibular relationship, with correct vertical dimensions of occlusion (VDO) and centric relations (CR). This short communication introduces a novel digital technique that allows to obtain the maxillomandibular record and transfer it throughout the treatment procedure.

Methods: The protocol consisted of the following steps: 1. Read More

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September 2021

Expanding Role of Technology in Rehabilitation After Lower-Extremity Joint Replacement: A Systematic Review.

JBJS Rev 2021 09 13;9(9). Epub 2021 Sep 13.

Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: The effectiveness of telehealth programs in the administration of rehabilitation and the monitoring of postoperative progress after joint replacement is not well studied. The purpose of the present study was to systematically review the currently available evidence on the use of smart-device technology and telehealth programs to guide and monitor postoperative rehabilitation following total joint arthroplasty and to assess their impact on outcomes following surgery.

Methods: A literature search of the MEDLINE database was performed using keywords "mobile," "app," "telehealth," "virtual," "arthroplasty," "outcomes," "joint replacement," "web based," "telemedicine," "TKA," "THA," "activity tracker," "fitness tracker," "monitor," "rehab," "online," and "stepcounter" in all possible combinations. Read More

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September 2021

Implementation of an Internet-Based Acceptance and Commitment Therapy for Promoting Mental Health Among Migrant Live-in Caregivers in Canada: Protocol.

JMIR Res Protoc 2021 Sep 13;10(9):e31211. Epub 2021 Sep 13.

Daphne Cockwell School of Nursing, Ryerson University, Toronto, ON, Canada.

Background: Psychological distress, isolation, feelings of powerlessness, and limited social support are realities faced by temporary migrant live-in caregivers in Canada. Furthermore, they experience multiple barriers in accessing mental health services due to their long work hours, limited knowledge of health resources, precarious employment, and immigration status.

Objective: The Women Empowerment - Caregiver Acceptance & Resilience E-Learning (WE2CARE) project is a pilot intervention research project that aims to promote the mental well-being and resiliency of migrant live-in caregivers. Read More

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September 2021

Development of Virtual Surveys for the COVID-19 Wave of the AGELESS Longitudinal Study in Malaysia.

Gerontology 2021 Aug 17:1-5. Epub 2021 Aug 17.

Ageing and Age-Associated Disorders Research Group, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Background: Rapid population aging occurring in developing nations necessitates innovation to ensure we continue to gain ground on aging research despite pandemic threats. While developed nations have resorted to virtual communications, this is challenging in developing nations due to poor internet connectivity and digital literacy.

Objectives: The aim of this study was to determine the feasibility of virtual data collection for a longitudinal study of aging assessing cognitive frailty in a middle-income Southeast Asian country. Read More

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A multi-disciplinary approach to weight management of school-age girls: a study protocol.

Pediatr Endocrinol Diabetes Metab 2021 ;27(2):76-81

Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: There is lack of data about the combination of multiple approaches to control being overweight and obesity in adolescents. This study aimed to evaluate the effect of a combination program including smart-phone nutrition education, physical activity, and cognitive behavioral therapy (CBT) programs in the management of obesity and overweight among elementary school girls in comparison with a traditional education method.

Material And Methods: The primary outcome of this study is the assessment of changes in anthropometric data after 10 weeks. Read More

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January 2021

Volatile anesthetic agents for life-threatening pediatric asthma: a multicenter, retrospective cohort study and narrative review.

Paediatr Anaesth 2021 Sep 12. Epub 2021 Sep 12.

Department of Pediatrics, University of South Florida College of Medicine, Tampa.

Background: Volatile anesthetic agents are described as rescue therapy for children invasively ventilated for critical asthma. Yet, data are currently limited to case series.

Aims: Using the Virtual Pediatric Systems database, we assessed children admitted to a pediatric intensive care unit invasively ventilated for life-threatening asthma and hypothesized ventilation duration and mortality rates would be lower for subjects exposed to volatile anesthetics compared to those without exposure. Read More

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September 2021

Phase-Property Diagrams for Multicomponent Oxide Systems toward Materials Libraries.

Adv Mater 2021 Sep 12:e2102301. Epub 2021 Sep 12.

Institute of Nanotechnology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.

Exploring the vast compositional space offered by multicomponent systems or high entropy materials using the traditional route of materials discovery, one experiment at a time, is prohibitive in terms of cost and required time. Consequently, the development of high-throughput experimental methods, aided by machine learning and theoretical predictions will facilitate the search for multicomponent materials in their compositional variety. In this study, high entropy oxides are fabricated and characterized using automated high-throughput techniques. Read More

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September 2021

COVID-19 pandemic: Is teenagers' health in crisis? An investigation into the effects of COVID-19 on self-reported mental and physical health of teenagers in secondary education.

Public Health Pract (Oxf) 2021 Nov 16;2:100099. Epub 2021 Mar 16.

King Edward VI High School for Girls, Birmingham, B15 2UB, United Kingdom.

Objectives: To evaluate the effects of the COVID-19 lockdown on the self-reported perception of physical and mental health, in a cohort of teenagers. To assess the extent to which these effects are perceived as detrimental.Non-directional Hypothesis - the perception of physical and mental health will change over the duration of the eight weeks, due to the effects of the lockdown, as a result of COVID-19. Read More

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November 2021

Using Simulation-Based Methods to Support Demonstration of Competencies Required by Micro-Credential Courses.

Cureus 2021 Aug 5;13(8):e16908. Epub 2021 Aug 5.

School of Nursing, York University, Toronto, CAN.

The rise of the digital revolution has disrupted entire industries and job markets, leading individuals to either upgrade or transfer their skills in order to continue within their designated fields or transition to new workplace contexts. Employers expect their employees to apply their knowledge to real-world settings, analyze and solve problems, connect choices to actions, and innovate and create. Moreover, the COVID-19 pandemic has exacerbated changes to the educational landscape by forcing online and remote contexts; physical distancing and other preventive measures have necessitated a shift towards increasing the use of disruptive digital technologies- extended reality (e. Read More

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Virtual test occlusion for assessing ischemic tolerance using computational fluid dynamics.

Surg Neurol Int 2021 27;12:378. Epub 2021 Jul 27.

Department of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.

Background: Ischemic tolerance has been evaluated by the balloon test occlusion (BTO) for cerebral aneurysms and tumors that might require parent artery occlusion during surgery. However, because of its invasiveness, a non-invasive evaluation method is needed. In this study, we assessed the possibility of virtual test occlusion using computational fluid dynamics (CFD) as a non-invasive alternative to BTO for evaluating ischemic tolerance. Read More

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Radiomics and Digital Image Texture Analysis in Oncology (Review).

Sovrem Tekhnologii Med 2021 1;13(2):97-104. Epub 2021 Jan 1.

Oncologist, Central City Clinical Hospital, 3 Letnyaya St., Kaliningrad, 236005, Russia.

One of the most promising areas of diagnosis and prognosis of diseases is radiomics, a science combining radiology, mathematical modeling, and deep machine learning. The main concept of radiomics is image biomarkers (IBMs), the parameters characterizing various pathological changes and calculated based on the analysis of digital image texture. IBMs are used for quantitative assessment of digital imaging results (CT, MRI, ultrasound, PET). Read More

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January 2021

Estimation of Fractional Photosynthetically Active Radiation From a Canopy 3D Model; Case Study: Almond Yield Prediction.

Front Plant Sci 2021 26;12:715361. Epub 2021 Aug 26.

Department of Plant Sciences, University of California, Davis, Davis, CA, United States.

Canopy-intercepted light, or photosynthetically active radiation, is fundamentally crucial for quantifying crop biomass development and yield potential. Fractional photosynthetically active radiation (PAR) (fPAR) is conventionally obtained by measuring the PAR both below and above the canopy using a mobile lightbar platform to predict the potential yield of nut crops. This study proposed a feasible and low-cost method for accurately estimating the canopy fPAR using aerial photogrammetry-based canopy three-dimensional models. Read More

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