965,589 results match your criteria vessel


A newly intervention strategy in preeclampsia: Targeting PD-1/Tim-3 signaling pathways to modulate the polarization of decidual macrophages.

FASEB J 2022 Jan;36(1):e22073

Institute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) are important immune checkpoint receptors that prevent an overreacted maternal immune response to fetal antigens during pregnancy. Disruption of complex immune regulation mechanisms is associated with adverse pregnancy outcomes, including preeclampsia (PE). Our recent study showed that the Tim-3 pathway was involved in the regulation of decidual macrophage polarization. Read More

View Article and Full-Text PDF
January 2022

Use of the Antegrade Posterior Interosseous Artery Flap for Coverage of Complex Elbow Wounds.

Plast Reconstr Surg 2021 Dec;148(6):1316-1319

From Norton Louisville Arm and Hand; and the Department of Orthopaedic Surgery, University of Louisville.

Summary: One of the most versatile soft-tissue flaps available for elbow coverage that is reliable, quick, and easy to perform, with minimal donor defect and without the sacrifice of a major blood vessel, is the antegrade posterior interosseous artery flap. A large amount of vascularized fascia can be dissected with the flap, and it can be useful in lining the elbow joint or any exposed implant(s). After flap harvest, the donor site is often amenable to primary closure or requires a simple skin graft for closure. Read More

View Article and Full-Text PDF
December 2021

Radiotherapy alone for pediatric patients with craniopharyngioma.

J Neurooncol 2021 Nov 30. Epub 2021 Nov 30.

Department of Radiation Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 210, Memphis, TN, 38105-3678, USA.

Purpose: Radiotherapy alone, without tumor-directed surgery, may be appropriate for selected patients with craniopharyngioma reducing the risks associated with neurosurgery. Understanding outcomes for patients with craniopharyngioma treated with radiotherapy alone will further refine patient selection and treatment options.

Methods: Since 2002, 13 children, adolescents and young adults, with craniopharyngioma were treated with radiotherapy alone and followed for disease control and functional outcomes at a single institution. Read More

View Article and Full-Text PDF
November 2021

Retinal Sensitivity Correlates With the Superficial Vessel Density and Inner Layer Thickness in Diabetic Retinopathy.

Invest Ophthalmol Vis Sci 2021 Nov;62(14):28

Université de Paris, Ophthalmology Department, AP-HP, Hôpital Lariboisière, F-75010, Paris, France.

Purpose: The purpose of this paper was to present our study on the relationship between the parafoveal sensitivity measured using microperimetry and the vessel density (VD) assessed by optical coherence tomography-angiography (OCT-A) in eyes with diabetic retinopathy (DR).

Methods: The observational case series was conducted in a tertiary ophthalmology center. Eyes with DR and without macular edema were consecutively included. Read More

View Article and Full-Text PDF
November 2021

Measuring Temporal and Spatial Variability of Red Blood Cell Velocity in Human Retinal Vessels.

Invest Ophthalmol Vis Sci 2021 Nov;62(14):29

School of Optometry, Indiana University, Bloomington, Indiana, United States.

Purpose: The retinal circulation regulates blood flow through various internal and external factors; however, it is unclear how locally these factors act within the retinal microcirculation. We measured the temporal and spatial variability of blood velocity in small retinal vessels using a dual-beam adaptive optics scanning laser ophthalmoscope.

Methods: In young healthy subjects (n = 3), temporal blood velocity variability was measured in a local vascular region consisting of an arteriole, capillary, and venule repeatedly over 2 days. Read More

View Article and Full-Text PDF
November 2021

Delayed Diagnosis of Paget-Schroetter Syndrome in a Patient with COVID-19.

R I Med J (2013) 2021 Dec 1;104(10):15-17. Epub 2021 Dec 1.

Warren Alpert Medical School of Brown University, Providence, RI; Department of Medicine, Kent Hospital, Warwick, RI.

Paget-Schroetter Syndrome (PSS), a subtype of thoracic outlet syndrome, is a rare condition defined as thrombosis of the axillosubclavian vein secondary to anatomical abnormalities or repetitive injury to vessel endothelium from exertion. In the setting of the COVID-19 pandemic, venous thrombosis in COVID-positive patients may be attributed to the well-described hypercoagulability associated with the viral syndrome, increasing the rate of misdiagnosis of PSS and delaying definitive treatment. We report a case of PSS in a 19-year-old male who presented to multiple health care providers with an upper extremity thrombus and was found to be SARS-CoV-2 positive on hospitalization. Read More

View Article and Full-Text PDF
December 2021

Successful Profiling of Plasmodium falciparum Gene Expression in Clinical Samples via a Custom Capture Array.

mSystems 2021 Nov 30:e0022621. Epub 2021 Nov 30.

Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.

genes encode Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens. These highly diverse antigens are displayed on the surface of infected erythrocytes and play a critical role in immune evasion and sequestration of infected erythrocytes. Studies of expression using non-leukocyte-depleted blood are challenging because of the predominance of host genetic material and lack of conserved segments. Read More

View Article and Full-Text PDF
November 2021

Numerical insights into the determinants of stent performance for the management of aneurysm with a visceral vessel attached.

Acta Bioeng Biomech 2021 ;23(2):41-53

Department of Applied Mechanics, Sichuan University, Chengdu, China.

Purpose: As the factors affecting the efficacy of the bare-metal stent in the treatment of aneurysm with a visceral vessel attached were not fully understood, we aimed to discuss the effects of different characteristics of the stent on the hemodynamics and flexibility in the treatment of the aneurysm.

Methods: Single-layer (with different strut widths) and multi-layer (with a different number of struts) stent models divided into three porosity groups, with porosities of 72.3, 60. Read More

View Article and Full-Text PDF
January 2021

Numerical analysis of the biomechanical effects on micro-vessels by ultrasound-driven cavitation.

Acta Bioeng Biomech 2021 ;23(1):95-105

College of Mathematics and Physics, University of South China, Hengyang, China.

Purpose: The goal of this study was to evaluate the biomechanical effects such as sonoporation or permeability, produced by ultrasound- driven microbubbles (UDM) within microvessels with various parameters.

Methods: In this study, a bubble-fluid-solid coupling system was established through combination of finite element method. The stress, strain and permeability of the vessel wall were theoretically simulated for different ultrasound frequencies, vessel radius and vessel thickness. Read More

View Article and Full-Text PDF
January 2021

The effect of stenosis rate and Reynolds number on local flow characteristics and plaque formation around the atherosclerotic stenosis.

Acta Bioeng Biomech 2021 ;23(1):135-147

Institute of Biomechanics, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, China.

Purpose: Atherosclerosis causes plaque to build-up in arteries. Effect of the specific local hemodynamic environment around an atherosclerotic plaque on the thrombosis formation does not remain quite clear but is believed to be crucial. The aim of this study is to uncover the flow effects on plaques formation. Read More

View Article and Full-Text PDF
January 2021

Reversible Takotsubo cardiomyopathy with non-revascularized concomitant severe coronary artery disease.

Echocardiography 2021 Nov 29. Epub 2021 Nov 29.

Department of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.

Takotsubo cardiomyopathy is a transient cardiac condition commonly triggered by a stressor, presenting with clinical features mimicking acute coronary syndromes. We report an unusual case of Takotsubo cardiomyopathy in a man with severe three-vessel coronary artery disease awaiting coronary bypass surgery who developed rapid spontaneous recovery of cardiac function before revascularization. Read More

View Article and Full-Text PDF
November 2021

The different forms of the left brachiocephalic vein visualized during cardiovascular implantable electronic device implantation procedures.

Folia Morphol (Warsz) 2021 Nov 30. Epub 2021 Nov 30.

1st Department of Cardiology, Medical University of Warsaw, Poland, Warsaw.

Background: Among the factors ensuring successful completion of such minimally invasive procedures as cardiac implantable electronic device (CIED) implantation and central venous catheter (CVC) placement are the morphometry and topography of the vessels used for cardiac lead or catheter advancement. Venous access through the left clavipectoral triangle makes use of the left brachiocephalic vein (BCV). The purpose of this study was to present the radiology images of various individual forms of this vessel observed during CIED implantation procedures. Read More

View Article and Full-Text PDF
November 2021

Wavelength optimization for the laser treatment of port wine stains.

Lasers Med Sci 2021 Nov 29. Epub 2021 Nov 29.

Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Based on the well-known principle of selective photothermolysis, laser has been a promising way for the treatment of port wine stains (PWSs). The laser wavelengths used for PWS's clinical treatment include but are not limited to pulsed dye laser (PDL) in 585-600 nm, long-pulse 755-nm alexandrite, and 1064-nm Nd:YAG lasers. The objective of this study was to investigate the optimal wavelength for PWS's laser treatment. Read More

View Article and Full-Text PDF
November 2021

Process Factors Affecting Reperfusion Time in Patients With ST-Segment Elevation Myocardial Infarction.

J Allied Health 2021 ;50(4):292-298

Dep. of Radiation Sciences, Virginia Commonwealth University, Box 843057, Richmond, VA 23284-3057, USA. Tel 804-229-4347, fax 804-828-9104.

Objective: To determine process factors impacting myocardial infarction reperfusion time.

Background: An ST-segment elevation myocardial infarction (STEMI) is a life-threatening condition that necessitates emergent medical treatment; longer reperfusion times are associated with negative patient outcomes. Therefore, time is critical in the treatment of a STEMI. Read More

View Article and Full-Text PDF
January 2021

[Transcranial color Doppler ultrasonography: methodology and usefulness for the study of patent foramen ovale in cryptogenic stroke].

G Ital Cardiol (Rome) 2021 Dec;22(12):988-999

Dipartimento Cardiotoracovascolare "De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Milano.

Non-invasive Doppler ultrasonographic study of cerebral arteries (transcranial Doppler, TCD) has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency (≤2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays a valid indication for TCD in the outpatient setting is the research of right-to-left shunting, responsible for the so-called "paradoxical embolism", most often due to patency of foramen ovale, which is responsible for the majority of cryptogenic strokes occurring in patients younger than 55 years. Read More

View Article and Full-Text PDF
December 2021

Diagnosis and surgical treatment of a rare hepatic angiomyolipoma with internal hemorrhage.

Ann Hepatobiliary Pancreat Surg 2021 Nov;25(4):532-535

Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Although angiomyolipoma (AML) is commonly found in the kidney, its appearance in the liver is rare. The first hepatic AML was reported by Ishak in 1976. Since then, there have been various reports of AML. Read More

View Article and Full-Text PDF
November 2021

Portal vein wedge resection and patch venoplasty using autologous and homologous vein grafts during surgery for hepatobiliary malignancies.

Ann Hepatobiliary Pancreat Surg 2021 Nov;25(4):509-516

Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Obtaining tumor-free resection margins is one of the most important factors for achieving favorable prognosis of patients undergoing resection for hepatobiliary malignancies. In this study, we present our experience of portal vein (PV) wedge resection and patch venoplasty using autologous or homologous vessel grafts for resecting perihilar cholangiocarcinoma, hepatocellular carcinoma, and distal bile duct cancer. Case 1 was 68-year-old male patient with type IV perihilar cholangiocarcinoma who underwent central bisectionectomy with caudate lobectomy and bile duct resection, and PV wedge resection and patch venoplasty with a cryopreserved iliac vein allograft patch. Read More

View Article and Full-Text PDF
November 2021

Combining Transcranial Doppler and EEG Data to Predict Delayed Cerebral Ischemia After Subarachnoid Hemorrhage.

Neurology 2021 Nov 29. Epub 2021 Nov 29.

Department of Neurology, Yale University, New Haven, CT

Background And Objectives: Delayed cerebral ischemia (DCI) is the leading complication of subarachnoid hemorrhage (SAH). Because DCI was traditionally thought to be caused by large vessel vasospasm, transcranial Doppler ultrasounds (TCDs) have been the standard of care. Continuous EEG has emerged as a promising complementary monitoring modality and predicts increased DCI risk. Read More

View Article and Full-Text PDF
November 2021

Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease: A Mendelian Randomization Study.

Neurology 2021 Nov 29. Epub 2021 Nov 29.

Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.

Objective-: Cardiovascular risk factors have been implicated in the etiology of Cerebral Small Vessel Disease (CSVD), however whether the associations are causal remains unclear in part due to the susceptibility of observational studies to reverse causation and confounding. Here we use Mendelian randomization (MR) to determine which cardiovascular risk factors are likely to be involved in the etiology of CSVD.

Methods-: We used data from large scale genome-wide association studies (GWAS) of European ancestry to identify genetic proxies for blood pressure, blood lipids, body mass index (BMI), type-II diabetes, smoking initiation, cigarettes per day and alcohol consumption. Read More

View Article and Full-Text PDF
November 2021

Anlotinib induces a T cell-inflamed tumor microenvironment by facilitating vessel normalization and enhances the efficacy of PD1 checkpoint blockade in neuroblastoma.

Clin Cancer Res 2021 Nov 29. Epub 2021 Nov 29.

Department of Pediatric Oncology, Tianjin Medical University Cancer Institute and Hospital

Purpose: Anlotinib has achieved good results in clinical trials of a variety of cancers. However, the effects of anlotinib on the tumor microenvironment (TME) and systemic immunity have not been reported. There is an urgent need to identify the underlying mechanism to reveal new opportunities for its application in neuroblastoma (NB) and other cancers. Read More

View Article and Full-Text PDF
November 2021

Venoarterial extracorporeal membrane oxygenation for life-threatening complications of percutaneous coronary and structural heart interventions.

Cardiovasc Revasc Med 2021 Nov 11. Epub 2021 Nov 11.

Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, MN, USA. Electronic address:

Percutaneous coronary or structural heart interventions may lead to complications, such as perforation and acute vessel closure that may in turn lead to cardiac arrest or cardiogenic shock. Moreover, acute coronary syndrome patients presenting with cardiogenic shock can be challenging to treat due to hemodynamic instability. In such cases, venoarterial extracorporeal membrane oxygenation (V-A ECMO) can provide hemodynamic stabilization and oxygenation allowing successful treatment of the complication or culprit lesion in acute coronary syndrome patients. Read More

View Article and Full-Text PDF
November 2021

Thrombectomy With and Without Computed Tomography Perfusion Imaging in the Early Time Window: A Pooled Analysis of Patient-Level Data.

Stroke 2021 Nov 30:STROKEAHA121034331. Epub 2021 Nov 30.

Neurological Institute, Cooper University Hospital, Camden, New Jersey (T.G.J.).

Background And Purpose: The optimal imaging paradigm for endovascular thrombectomy (EVT) patient selection in early time window (0-6 hours) treated acute ischemic stroke patients remains uncertain. We aimed to compare post-EVT outcomes between patients who underwent prerandomization basic (noncontrast computed tomography [CT], CT angiography only) versus additional advanced imaging (computed tomography perfusion [CTP] imaging) and to determine the association of performance of prerandomization CTP imaging with clinical outcomes.

Methods: The HERMES collaboration (Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials) pooled patient-level data from randomized controlled trials comparing EVT with usual care for acute ischemic stroke due to anterior circulation large vessel occlusion. Read More

View Article and Full-Text PDF
November 2021

Evaluating the adsorption performance of Tenax TA® in different containers: An isolation tool to study the bioaccessibility of nitro-PAHs in spiked soil.

Sci Total Environ 2022 Feb 20;806(Pt 1):150429. Epub 2021 Sep 20.

School of Environment, Nanjing Normal University, Jiangsu Engineering Lab of Water and Soil Eco-Remediation, Nanjing 210023, China; Green Economy Development Institute, Nanjing University of Finance and Economics, Nanjing 210023, China.

The improved in vitro gastrointestinal simulation methods, with the addition of the adsorption sink, are considered as a promising tool for predicting the bioaccessibility of contaminants. However, the problem associated with the recovery of the adsorption sink from the complex matrix needs more understand. Although previous studies tried to solve this shortcoming by using the containers (a vessel to hold the adsorption sink), there is no systematic comparison study on the impact of containers on bioaccessibility till now, especially for nitro-polycyclic aromatic hydrocarbons (nitro-PAHs). Read More

View Article and Full-Text PDF
February 2022

Structural and vascular changes of the choroid in polypoidal choroidal vasculopathy after intravitreal anti-VEGF therapy.

Ophthalmologica 2021 Nov 29. Epub 2021 Nov 29.

Introduction: To identify the changes in vessel density (VD) of choriocapillaris (CC) and in subfoveal choroidal thickness (SFCT) and to evaluate their correlation with functional response after three monthly intravitreal injections of Ranibizumab (loading phase) in patients affected by Polypoidal Choroidal Vasculopathy (PCV).

Methods: A total of 30 eyes of 30 PCV patients and 30 eyes of 30 healthy subjects as control group were enrolled in this prospective study. The best corrected visual acuity (BCVA) was measured at baseline and after one month from third intravitreal injections in each patient. Read More

View Article and Full-Text PDF
November 2021

Application of C-band sentinel-1A SAR data as proxies for detecting oil spills of Chennai, East Coast of India.

Mar Pollut Bull 2021 Nov 26;174:113182. Epub 2021 Nov 26.

Department of Geology, Yogi Vemana University, Kadapa, Andhra Pradesh, India. Electronic address:

This paper presents the utilization of Synthetic Aperture Radar (SAR) data for monitoring and detection of oil spills. In this work, a case study of an oil spill has been investigated using C-band Sentinel-1A SAR data to detect the oil spill that occurred on 28 January 2017, near Ennore port, Chennai, India. Oil spill damages marine ecosystems causing serious environmental effects. Read More

View Article and Full-Text PDF
November 2021

New vascular structure in broiler breast: breast-vessel.

Poult Sci 2021 Nov 10;101(1):101565. Epub 2021 Nov 10.

Poultry Quality and Animal Nutrition Center of the Valencia Region (CECAV), Alquerías del Niño Perdido, Castellón 12539, Spain; Department of Animal Production and Health, Veterinary Public Health and Food Science and Technology, Institute of Biomedical Sciences, Faculty of Veterinary Medicine, Cardenal Herrera-CEU University, 46113 Moncada, Spain.

Chickens intensively selected for accelerating growth rate and enhanced muscle mass has resulted in the occurrence of breast alterations with a negative consumers perception. Together with the already known breast abnormalities (White Striping, Wooden Breast and Spaghetti Meat) a new one has been described by the consumers as a "long and thin worm". For this reason, the aim of this work was to macroscopically and microscopically describe this structure in broiler breast. Read More

View Article and Full-Text PDF
November 2021

Validation of the Academic Research Consortium for High Bleeding Risk criteria in Chinese patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention.

Thromb Res 2021 Nov 25;209:16-22. Epub 2021 Nov 25.

Emergency and Critical Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, People's Republic of China. Electronic address:

Background: This study aims to validate the Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria in Chinese patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) who received both oral anticoagulants (OAC) and antiplatelet therapy (APT).

Methods: 930 consecutive patients with AF and ACS or undergoing PCI receiving both OAC and APT were recruited and followed up for 1 year. The primary endpoint was BARC type 3 or 5 bleeding. Read More

View Article and Full-Text PDF
November 2021

Microsurgical Resection of a Giant Posterior Fossa Aneurysmal Malformation in a 21-Month-Old.

World Neurosurg 2021 Nov 26. Epub 2021 Nov 26.

Department of Neurosciences and Pediatrics, University of California San Diego, San Diego, California. Electronic address:

Pediatric aneurysms commonly occur in the vertebrobasilar circulation with complex morphologies. "Aneurysmal malformations", or fistulous vessel dilations without a nidus have also been described. Vessel friability and sensitivity to blood loss can complicate surgery. Read More

View Article and Full-Text PDF
November 2021

Use of Coronary Intravascular Lithotripsy: A Comprehensive Review of Literature.

Curr Probl Cardiol 2021 Nov 26:101076. Epub 2021 Nov 26.

University of Texas Medical Branch, Department of Internal Medicine, Division of Cardiovascular Diseases, Galveston, TX, USA.

Severe coronary artery calcification (CAC) is associated with high rate of procedural complications. The current techniques that facilitate PCI in moderate to severe CAC have significant risk of complications, including periprocedural myocardial infarction (MI), dissection, perforation and transient atrioventricular block. Coronary Intravascular lithotripsy (IVL) is a novel technology for the treatment of moderate to severe calcified lesions. Read More

View Article and Full-Text PDF
November 2021