13,487 results match your criteria ventricle size

Evaluation of echocardiographic derived parameters for right ventricular size and function using cardiac magnetic resonance imaging.

Echocardiography 2021 Jul 19. Epub 2021 Jul 19.

Division of Cardiology, Department of Medicine, White River Junction VA Medical Center, White River Junction, Vermont, USA.

Background: Cardiac Magnetic Resonance Imaging (cMRI) is the gold standard for right ventricular (RV) assessment due to its high spatial resolution. The American Society of Echocardiography (ASE) recommends eight structural and six functional quantitative parameters for evaluation of the RV. This study sought to simplify echocardiographic RV assessment by examining the relative diagnostic value of the echo recommended parameters by applying them to cMRI imaging of the RV. Read More

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Cerebrospinal fluid may flow out from the brain through the frontal skull base and choroid plexus: a gold colloid and cadaverine injection study in mouse fetus.

Childs Nerv Syst 2021 Jul 20. Epub 2021 Jul 20.

Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Sugitani, Toyama, Japan.

Purpose: It has been commonly accepted for a long time that the cerebrospinal fluid (CSF) drains into arachnoid granulations from the subarachnoid space to the dural venous sinus unidirectionally. However, recently, periventricular capillaries and lymphatic concepts have been introduced. The CSF moves along the perivascular space and drains into the capillary vessels or meningeal lymphatic tissues. Read More

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2D Echocardiographic Right Ventricular Size and Systolic Function Measurements Stratified by Sex, Age and Ethnicity: Results of the World Alliance of Societies of Echocardiography Study.

J Am Soc Echocardiogr 2021 Jul 15. Epub 2021 Jul 15.

University of Chicago, Chicago IL.

Background: Echocardiographic assessment of right ventricular (RV) systolic function is an important component of clinical decision-making. While societal guidelines have worked to define normal ranges of RV size and function, they have not included the impact of age, sex and ethnicity on these parameters, as they have for the left ventricle. The World Alliance of Societies of Echocardiography (WASE) study was designed to investigate the effect of age, sex and ethnicity on all cardiac chambers. Read More

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Impact of right ventricular systolic function in patients with significant tricuspid regurgitation. A cardiac magnetic resonance study.

Int J Cardiol 2021 Jul 14. Epub 2021 Jul 14.

Cardiology Department, University Hospital Ramón y Cajal, Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

Background: Right ventricle (RV) dilatation and dysfunction are established criteria for intervention in severe tricuspid regurgitation (TR); however thresholds to support intervention are lacking. New measures of RV function such as RV shortening (RVS) and effective RV ejection fraction (eRVEF) may be earlier markers of RV dysfunction.

Purpose: to compare the prognostic impact of different parameters of RV function and to describe cut-off values of RV size/function and TR severity of poor prognosis. Read More

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Preoperative mitral annulus size - Can we get it right?

Ann Card Anaesth 2021 Jul-Sep;24(3):315-318

Department of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Objective: We looked for a correlation between the surgically measured mitral valve size and the cardiac dimensions (left ventricle internal diameter, left atrial size, aorta size, and body surface area) measured by preoperative and intraoperative echocardiography. We also assessed to see if we could predict the mitral prosthesis size based on the correlation data obtained.

Methods: The hospital records of 180 patients who underwent mitral valve replacement (MVR) with TTK Chitra valve between January 2008 and December 2012 at our hospital, were studied. Read More

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Evaluation of Posterior Fossa Biometric Measurements on Fetal MRI in the Evaluation of Dandy-Walker Continuum.

AJNR Am J Neuroradiol 2021 Jul 15. Epub 2021 Jul 15.

University of Cincinnati College of Medicine (U.D.N., B.M.K.-F., P.S.H., C.V.), Cincinnati, Ohio.

Background And Purpose: Dandy-Walker malformation, vermian hypoplasia, and Blake pouch remnant represent a continuum of anomalies and are common reasons for referral for fetal MR imaging. This study aimed to determine biometric measurements that quantitatively delineate these 3 posterior fossa phenotypes.

Materials And Methods: Our single-center institutional review board approved a retrospective analysis of all fetal MRIs for posterior fossa malformations, including Dandy-Walker malformation, vermian hypoplasia, and Blake pouch remnant. Read More

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An image registration framework to estimate 3D myocardial strains from cine cardiac MRI in mice.

Funct Imaging Model Heart 2021 Jun 18;12738:273-284. Epub 2021 Jun 18.

Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA.

Accurate and efficient quantification of cardiac motion offers promising biomarkers for non-invasive diagnosis and prognosis of structural heart diseases. Cine cardiac magnetic resonance imaging remains one of the most advanced imaging tools to provide image acquisitions needed to assess and quantify in-vivo heart kinematics. The majority of cardiac motion studies are focused on human data, and there remains a need to develop and implement an image-registration pipeline to quantify full three-dimensional (3D) cardiac motion in mice where ideal image acquisition is challenged by the subject size and heart rate and the possibility of traditional tagged imaging is hampered. Read More

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Left-dominant arrhythmogenic cardiomyopathy: an association with desmoglein-2 gene mutation-a case report.

Eur Heart J Case Rep 2021 Jun 23;5(6):ytab213. Epub 2021 Jun 23.

Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Akron General, Akron, 1 Akron General Ave, Akron, OH, USA 44307, USA.

Background: Desmosomes are specialized intercellular adhesive junctions of cardiac and epithelial cells that provide intercellular mechanical coupling through glycoproteins, one of which is desmoglein (DSG). DSG-2 mutations are frequently associated with biventricular arrhythmogenic cardiomyopathy (ACM). We report a case of left-dominant ACM in a patient who initially was misclassified as dilated cardiomyopathy (DCM). Read More

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Left Ventricular Flow Dynamics with the HeartMate3 Left Ventricular Assist Device: Effect of Inflow Cannula Position and Speed Modulation.

ASAIO J 2021 Jul 8. Epub 2021 Jul 8.

From the Bioengineering Program, Department of Mechanical Engineering, San Diego State University, San Diego, California.

Improper left ventricular assist device (LVAD) inflow cannula (IC) positioning creates areas of stasis and low pulsatility that predispose thromboembolism, but may be mitigated with LVAD speed modulation. A mock loop study was performed to assess the sensitivity of left ventricle (LV) flow architecture to IC position and speed modulation during HeartMate3 support. System pressure, flow, and the time-resolved velocity field were measured within a transparent silicone LV for three IC angles and three IC insertion depths at matched levels of cardiac function and LVAD speed. Read More

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Surgical ablation supplemented by ethanol injection for ventricular tachycardia refractory to percutaneous ablation.

J Cardiovasc Electrophysiol 2021 Jul 13. Epub 2021 Jul 13.

Division of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Background: A combination of endocardial and epicardial approaches has improved the overall success rate of ventricular tachycardia (VT) ablation in patients with cardiomyopathy. However, the origins of some VTs are truly intramural or close to coronary arteries, which makes this combined strategy either prone to failure or too risky.

Objectives: This observational study aimed to explore the feasibility and efficacy of direct epicardial ablation combined with intramural ethanol injection via surgical approach for inaccessible intramural VTs or VTs too close to coronary arteries. Read More

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Real-time 3D-echocardiography of the right ventricle-paediatric reference values for right ventricular volumes using knowledge-based reconstruction: a multicentre study.

Quant Imaging Med Surg 2021 Jul;11(7):2905-2917

Department of Congenital Heart Defects, Heart and Diabetes Centre North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.

Background: Real-time 3D echocardiography is a promising method for non-invasive assessment of right ventricular performance in children with congenital heart disease. Volume quantification using knowledge-based reconstruction (KBR) enables the calculation of right ventricular dimensions by matching endocardial landmarks with a reference library of right ventricular shapes. However, paediatric reference values for volumes based on KBR are missing. Read More

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Left ventricle-mitral valve ring size mismatch following ring annuloplasty for nonischemic dilated cardiomyopathy.

J Thorac Cardiovasc Surg 2021 Jun 8. Epub 2021 Jun 8.

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. Electronic address:

Background: In patients with ischemic mitral regurgitation (MR) undergoing restrictive mitral annuloplasty (RMA), the ratio of left ventricular (LV) end-systolic dimension (LVESD) to mitral valve (MV) ring size (ie, LV-MV ring mismatch) is associated with postoperative recurrent MR. However, the impact of LV-MV ring mismatch on postoperative recurrent MR, LV function recovery, and long-term survival in patients with nonischemic dilated cardiomyopathy (DCM) remains unknown.

Methods: Sixty-six patients with nonischemic DCM (mean LVESD, 62 mm) underwent RMA (mean ring size, 26 mm) between 2003 and 2014. Read More

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Electrocardiographic changes are strongly correlated with the extent of cardiac inflammation in mice with Coxsackievirus B3-induced viral myocarditis.

Cardiovasc Pathol 2021 Jul 7:107367. Epub 2021 Jul 7.

Department of Pathology, Amsterdam University Medical Centers, location VUmc and AMC, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.

Objective: Viral myocarditis (VM) can induce changes in myocardial electrical conduction and arrhythmia. However, their relationship with myocarditis-associated arrhythmic substrates in the heart such as inflammation and fibrosis is relatively unknown. This we have analyzed in the present study. Read More

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Craniopharyngiomas primarily affecting the hypothalamus.

Handb Clin Neurol 2021 ;181:75-115

Independent Medical Translator, Jenkintown, PA, United States.

The concept of craniopharyngiomas (CPs) primarily affecting the hypothalamus, or "hypothalamic CPs" (Hy-CPs), refers, in a restrictive sense, to the subgroup of CPs originally developing within the neural tissue of the infundibulum and tuber cinereum, the components of the third ventricle floor. This subgroup, also known as infundibulo-tuberal CPs, largely occupies the third ventricle and comprises up to 40% of this pathological entity. The small subgroup of strictly intraventricular CPs (5%), lesions wholly developed within the third ventricle above an anatomically intact third ventricle floor, can also be included within the Hy-CP category. Read More

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January 2021

The median preoptic nucleus: A major regulator of fluid, temperature, sleep, and cardiovascular homeostasis.

Handb Clin Neurol 2021 ;179:435-454

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.

Located in the midline lamina terminalis of the anterior wall of the third ventricle, the median preoptic nucleus is a thin elongated nucleus stretching around the rostral border of the anterior commissure. Its neuronal elements, composed of various types of excitatory glutamatergic and inhibitory GABAergic neurons, receive afferent neural signals from (1) neighboring subfornical organ and organum vasculosum of the lamina terminalis related to plasma osmolality and hormone concentrations, e.g. Read More

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January 2021

Intramyocardial delivery of human cardiac stem cell spheroids with enhanced cell engraftment ability and cardiomyogenic potential for myocardial infarct repair.

J Control Release 2021 Jul 2;336:499-509. Epub 2021 Jul 2.

Department of Pharmacy, Ewha Womans University, 52, Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea. Electronic address:

Strategies for stem cell-based cardiac regeneration and repair are key issues for the ischemic heart disease (IHD) patients with chronic complications related to ischemic necrosis. Cardiac stem cells (CSCs) have demonstrated high therapeutic efficacy for IHD treatment owing to their specific cardiac-lineage commitment. The therapeutic potential of CSCs could be further enhanced by designing a cellular spheroid formulation. Read More

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Cardiovascular Development and Congenital Heart Disease Modeling in the Pig.

J Am Heart Assoc 2021 Jul 3;10(14):e021631. Epub 2021 Jul 3.

Department of Developmental Biology University of Pittsburgh School of Medicine Pittsburgh PA.

Background Modeling cardiovascular diseases in mice has provided invaluable insights into the cause of congenital heart disease. However, the small size of the mouse heart has precluded translational studies. Given current high-efficiency gene editing, congenital heart disease modeling in other species is possible. Read More

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A giant left atrial myxoma causing mitral valve pseudostenosis - a mimicker.

J Community Hosp Intern Med Perspect 2021 Jun 21;11(4):523-527. Epub 2021 Jun 21.

Cardiology Department, McLaren Health Care, Flint/Michigan State University, Flint, MI, USA.

The clinical features of cardiac myxoma vary significantly from asymptomatic to severe cardiovascular complications like atrioventricular valve obstruction and thromboembolism depending on the location, size, and mobility of the tumor. Echocardiography is the diagnostic study of choice, and surgical resection is the method of choice to prevent complications. We report a case of a 47-year-old female who presented with exertional dyspnea, malaise, and weight loss. Read More

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Multimodal Simulation of a Novel Device for a Safe and Effective External Ventricular Drain Placement.

Front Neurosci 2021 14;15:690705. Epub 2021 Jun 14.

Department of Medical Physics, IRCCS University Hospital of Bologna, Bologna, Italy.

Background: External ventricular drain (EVD) placement is mandatory for several pathologies. The misplacement rate of the EVD varies widely in literature, ranging from 12.3 to 60%. Read More

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Correlating computed tomographic angiography of pulmonary circulation with clinical course and disease burden in patients with tetralogy of Fallot and pulmonary atresia.

Eur J Radiol Open 2021 15;8:100363. Epub 2021 Jun 15.

Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, Bangkok, 10400, Thailand.

Purpose: To determine the type of pulmonary circulation (PC) in patients with tetralogy of Fallot (TOF) and pulmonary atresia (TOF-PA) with the use of computed tomographic angiography (CTA), and describe their clinical courses, corrective surgery and disease burden.

Methods: 145 patients (median age 4 years, interquartile range: IQR2-8 years) were analyzed for PC which divided into 5 CTA-types and 11 subtypes based on presence of main pulmonary trunk (MPA) and confluent pulmonary arteries (confluence-PAs), presence of ductus arteriosus or major aortopulmonary collateral arteries (MAPCAs), respectively. Pulmonary arteries (PAs) were assessed by McGoon ratio and arborization. Read More

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A New Model of Heart Failure Post-Myocardial Infarction in the Rat.

J Vis Exp 2021 Jun 10(172). Epub 2021 Jun 10.

College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine; Shandong Co-Innovation Center of Classic TCM Formula, Shandong Provincial Education Department;

Ligation of the left anterior descending (LAD) coronary artery has been widely used to establish the rat model of heart failure (HF) post myocardial infarction (MI). However, the disadvantages of this model include high mortality rate after ligation and larger variations both in the infarct size and the degree of impaired cardiac function. In addition, a ventilator or exteriorization of the heart is indispensable for the previous models, which complicates the procedure during the ligation. Read More

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Adult Obstructive Cor Triatriatum with Severe Mitral Regurgitation: A Case Report.

Heart Surg Forum 2021 Jun 25;24(3):E578-E579. Epub 2021 Jun 25.

Department of Cardiovascular Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Adult cor triatriatum sinister associated with severe mitral regurgitation is extremely rare. As these obstructive cor triatriatum feature hemodynamics that mimic mitral stenosis, a pressure load is theoretically generated only on the left atrial proximal chamber, and therefore the left ventricle is less likely to suffer volume loading. Here, we report a surgical case with such rare hemodynamics. Read More

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Does the size of pulmonary artery impact on recoarctation of the aorta after the Norwood procedure without patch?

Interact Cardiovasc Thorac Surg 2021 Jun 24. Epub 2021 Jun 24.

Department of Cardiovascular Surgery, Okayama University Hospital, Okayama, Japan.

Objectives: This study aimed to evaluate whether recoarctation of the aorta (reCoA) after the Norwood procedure for hypoplastic left heart syndrome correlates with pre- and postoperative anatomic factors.

Methods: This retrospective study included 48 patients who underwent Norwood procedure with right ventricle-to-pulmonary artery conduit between 2009 and 2017. Anatomical factors such as preoperative length, diameter of the main pulmonary artery (MPA), and postoperative neoaortic arch angle stratified by arch reconstruction technique were analysed using the receiver operating characteristic analysis. Read More

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The Ependymal Region Prevents Glioblastoma From Penetrating Into the Ventricle via a Nonmechanical Force.

Front Neuroanat 2021 7;15:679405. Epub 2021 Jun 7.

Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Intraventricular penetration is rare in glioblastoma (GBM). Whether the ependymal region including the ependyma and subventricular zone (SVZ) can prevent GBM invasion remains unclear.

Methods: Magnetic resonance imaging (MRI) and haematoxylin-eosin (HE) staining were performed to evaluate the size and anatomical locations of GBM. Read More

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Effect of cannulation site on emboli travel during cardiac surgery.

J Cardiothorac Surg 2021 Jun 23;16(1):181. Epub 2021 Jun 23.

Department of Cardiac Surgery, Istituto Cardiocentro Ticino, Lugano, Switzerland.

Background: During cardiac surgery, micro-air emboli regularly enter the blood stream and can cause cognitive impairment or stroke. It is not clearly understood whether the most threatening air emboli are generated by the heart-lung machine (HLM) or by the blood-air contact when opening the heart. We performed an in vitro study to assess, for the two sources, air emboli distribution in the arterial tree, especially in the brain region, during cardiac surgery with different cannulation sites. Read More

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Whole-Heart High-Resolution Late Gadolinium Enhancement: Techniques and Clinical Applications.

J Magn Reson Imaging 2021 Jun 21. Epub 2021 Jun 21.

IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Bordeaux, France.

In cardiovascular magnetic resonance, late gadolinium enhancement (LGE) has become the cornerstone of myocardial tissue characterization. It is widely used in clinical routine to diagnose and characterize the myocardial tissue in a wide range of ischemic and nonischemic cardiomyopathies. The recent growing interest in imaging left atrial fibrosis has led to the development of novel whole-heart high-resolution late gadolinium enhancement (HR-LGE) techniques. Read More

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Customising the surgical management for intraventricular meningiomas - 'one size doesn't fit all'.

Br J Neurosurg 2021 Jun 21:1-6. Epub 2021 Jun 21.

Department of Neurosurgery, PGIMER, Chandigarh, India.

Background: Intraventricular meningiomas are uncommon and gross total resection is the recommended treatment. However, total resection may not always be possible, especially in locations in which the lesions are adherent to veins and neural structures. We share our experience with intraventricular meningiomas, focusing on the management strategies and outcomes. Read More

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Tricuspid Valve Tethering Is Associated with Residual Regurgitation after Valve Repair in Hypoplastic Left Heart Syndrome: A Three-Dimensional Echocardiographic Study.

J Am Soc Echocardiogr 2021 Jun 18. Epub 2021 Jun 18.

Division of Pediatric Cardiology, Department of Pediatrics, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Background: Tricuspid valve regurgitation (TR) is a risk factor for morbidity and mortality in children with hypoplastic left heart syndrome (HLHS). Surgical tricuspid valve (TV) repair is common, but durable repair remains challenging. The aim of this study was to examine mechanisms of TR requiring surgery, features associated with unsuccessful repair, and TV changes after surgical repair. Read More

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High accessory pathway conductivity blocks antegrade conduction in Wolff-Parkinson-White syndrome: A simulation study.

J Arrhythm 2021 Jun 24;37(3):683-689. Epub 2021 Mar 24.

Department of Pediatric Cardiology Shizuoka Children's Hospital Shizuoka Japan.

Background: Wolff-Parkinson-White (WPW) syndrome is characterized by an anomalous accessory pathway (AP) that connects the atrium and ventricles, which can cause abnormal myocardial excitation and cardiac arrhythmias. The morphological and electrophysiological details of the AP remain unclear. The size and conductivity of the AP may affect conduction and WPW syndrome symptoms. Read More

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Level of kisspeptin-10 in patients with multiple sclerosis and the association between third ventricle diameter size and vitamin D level.

Physiol Int 2021 Jun 16. Epub 2021 Jun 16.

4Department of Neurology, Abdulkadir Yuksel Hospital, Gaziantep, Turkey.

Objective: Multiple sclerosis (MS) is a chronic and progressive neurological disease affecting the central nervous system (CNS). Some studies report an association between MS pathogenesis and cytokines. Here, we aimed to determine and evaluate serum kisspeptin-10 level in MS patients and its related clinic parameters. Read More

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