1,463 results match your criteria ventilation dialysis


Trends over time in the risk of adverse outcomes among patients with SARS-CoV-2 infection.

Clin Infect Dis 2021 May 11. Epub 2021 May 11.

Division of Gastroenterology, Veterans Affairs Puget Sound Healthcare System and University of Washington, Seattle, WA, USA.

Background: We aimed to describe trends in adverse outcomes among patients who tested positive for SARS-CoV-2 between February and September 2020 within a national healthcare system.

Methods: We identified enrollees in the national U.S. Read More

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COVID-19: Perspectives From Frontline Critical Care Nurses in New York.

Nurs Adm Q 2021 Apr 29. Epub 2021 Apr 29.

New York University Langone Health, New York.

New York City quickly became the epicenter of coronavirus disease-2019 (COVID-19) in early March of 2020. While hospitals were aware of the potential of COVID-19, the volume of critically ill patients that flooded the hospitals in the New York City area was clearly not anticipated. Hospital staff worked quickly to create COVID-19-free areas, but were overcome with the volume of COVID-positive critically ill patients. Read More

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Use of peritoneal dialysis for acute kidney injury during the COVID-19 pandemic in New York City: a multicenter observational study.

Kidney Int 2021 Apr 28. Epub 2021 Apr 28.

Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

To demonstrate feasibility of acute peritoneal dialysis (PD) for acute kidney injury during the coronavirus disease 2019 (COVID-19) pandemic, we performed a multicenter, retrospective, observational study of 94 patients who received acute PD in New York City in the spring of 2020. Patient comorbidities, severity of disease, laboratory values, kidney replacement therapy, and patient outcomes were recorded. The mean age was 61 ± 11 years; 34% were women; 94% had confirmed COVID-19; 32% required mechanical ventilation on admission. Read More

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COVID-2019 fundamentals.

J Am Dent Assoc 2021 05 5;152(5):354-363. Epub 2021 Feb 5.

Background: A novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified at the end of 2019. The disease caused by SARS-CoV-2 was named COVID-19. The main purpose of this review was to provide an overview of SARS-CoV-2. Read More

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STratification risk analysis in OPerative management (STOP score) for drug-induced endocarditis.

J Card Surg 2021 Apr 24. Epub 2021 Apr 24.

Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Background: The opioid epidemic has seen a drastic increase in the incidence of drug-associated infective endocarditis (IE). No clinical tool exists to predict operative morbidity and mortality in patients undergoing surgery.

Methods: A multi-institutional database was reviewed between 2011 and 2018. Read More

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Continuous renal replacement therapy in intensive care patients with COVID-19; survival and renal recovery.

J Crit Care 2021 Apr 16;64:125-130. Epub 2021 Apr 16.

Dept of Perioperative Medicine and Intensive Care, Karolinska University Hospital, 171 76, Stockholm, Sweden. Electronic address:

Background: Outcome for critically ill patients with COVID-19 treated with continuous renal replacement therapy (CRRT) is largely unknown. We describe mortality and renal outcome in this group.

Methods: This observational study was conducted at a university hospital in Sweden. Read More

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[Perioperative strategies: taking care of the elderly patient with severe advanced comorbidities needing acute surgery.]

Recenti Prog Med 2021 Apr;112(4):250-261

In the common clinical practice the perioperative risk assessment of an acute surgical patient with advanced chronic comorbidities is carried out independently by surgeon and anesthesiologist, usually in two different steps. While the surgeon evaluates the risk mainly in relation to the surgical outcome, the perioperative risk assessment regarding the weight of the coexisting medical condition on the quality of recovery in the short- mid- and long-term is all about the anesthesiologist evaluation. When frailty and/or comorbidities are so serious that will make surgery seem futile, the patient's assessment on one hand, and the decisions regarding the further clinical waypoint on the other, have to be discussed firstly between surgeons and anesthesiologists before being shared with the patients and their relatives. Read More

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A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structured summary of a study protocol for a randomised, controlled trial.

Trials 2021 Apr 19;22(1):288. Epub 2021 Apr 19.

Royal College of Surgeons in Ireland, Dublin, Ireland.

Objectives: The primary objective is to demonstrate that, in patients with PCR-confirmed SARS-CoV-2 resulting in Acute Respiratory Distress Syndrome (ARDS), administration of 120mg/kg of body weight of intravenous Prolastin®(plasma-purified alpha-1 antitrypsin) reduces circulating plasma levels of interleukin-6 (IL-6). Secondary objectives are to determine the effects of intravenous Prolastin® on important clinical outcomes including the incidence of adverse events (AEs) and serious adverse events (SAEs).

Trial Design: Phase 2, randomised, double-blind, placebo-controlled, pilot trial. Read More

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Risk Factors for Perioperative Morbidity in Adults Undergoing Cardiac Surgery at Children's Hospitals.

Ann Thorac Surg 2021 Apr 14. Epub 2021 Apr 14.

Division of Cardiothoracic Surgery, Department of Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA.

Background: Increasing numbers of adult with congenital heart disease (ACHD) undergo cardiac surgery in children's hospitals, yet surgical outcomes data are limited. We sought to better understand the impact of preoperative risk factors on postoperative complications and cardiac intensive care unit (CICU) length of stay (LOS).

Methods: Surgical CICU admissions for patients > 18 years in the Pediatric Cardiac Critical Care Consortium registry (8/2014-1/2019; 34 hospitals) were included. Read More

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Predictors of unplanned 30-day readmissions after coronary artery bypass graft: a systematic review and meta-analysis of cohort studies.

Eur J Cardiovasc Nurs 2021 Apr 17. Epub 2021 Apr 17.

Ajou University College of Nursing and Research Institute of Nursing Science, 164, Worldcup-Ro, Yeongtong-Gu, Suwon 16499, Republic of Korea.

Aims: Coronary artery bypass graft (CABG) is one of the most performed cardiac surgery globally. CABG is known to have a high rate of short-term readmissions. The 30-day unplanned readmission rate as a quality measure is associated with adverse health outcomes. Read More

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Surge and Mortality in ICUs in New York City's Public Healthcare System.

Crit Care Med 2021 Apr 5. Epub 2021 Apr 5.

1 Division of Pulmonary, Critical Care, and Sleep Medicine, New York University School of Medicine, Bellevue Hospital, New York, NY. 2 Office of Population Health, NYC Health + Hospitals, New York, NY. 3 Division of Infectious Diseases and Immunology, NYU Grossman School of Medicine, Bellevue Hospital, New York, NY. 4 Department of Nursing, NYC Health + Hospitals Queens, New York, NY. 5 Data & Analytics (DnA)-Epic Reporting Team, NYC Health + Hospitals, New York, NY.

Objectives: To evaluate the impact of ICU surge on mortality and to explore clinical and sociodemographic predictors of mortality.

Design: Retrospective cohort analysis.

Setting: NYC Health + Hospitals ICUs. Read More

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The use of blood and blood products in aortic surgery is associated with adverse outcomes.

J Thorac Cardiovasc Surg 2021 Mar 15. Epub 2021 Mar 15.

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pa; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa.

Objective: To report long-term outcomes after deep hypothermic circulatory arrest (DHCA) with or without perioperative blood or blood products.

Methods: All patients who underwent proximal aortic surgery with DHCA from 2011 to 2018 were propensity matched according to baseline characteristics. Primary outcomes included short- and long-term mortality. Read More

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Epidemiology of COVID-19 Infection in Hospitalized End-Stage Kidney Disease Patients in a Predominantly African-American Population.

Am J Nephrol 2021 7;52(3):190-198. Epub 2021 Apr 7.

Division of Renal Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Background: End-stage kidney disease patients on dialysis are particularly susceptible to COVID-19 infection due to comorbidities, age, and logistic constraints of dialysis making social distancing difficult. We describe our experience with hospitalized dialysis patients with COVID-19 and factors associated with mortality.

Methods: From March 1, 2020, to May 31, 2020, all dialysis patients admitted to 4 Emory Hospitals and tested for COVID-19 were identified. Read More

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Acute Renal Failure in a Patient With Severe Acute Respiratory Syndrome Coronavirus 2.

Cureus 2021 Feb 17;13(2):e13406. Epub 2021 Feb 17.

Nephrology, Trinitas Regional Medical Center, Elizabeth, USA.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious viral pathogen with high morbidity and mortality rate. The infection affects multiple organ systems leading to systemic organ failure. There is an increased incidence of acute kidney injury (AKI) in patients who become critically ill. Read More

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February 2021

Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COVID-19 disease severity and indicator of the need for mechanical ventilation, ARDS and mortality.

Ann Intensive Care 2021 Mar 22;11(1):50. Epub 2021 Mar 22.

Department of Internal Medicine IV, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Background: COVID-19 pneumonia and subsequent respiratory failure is causing an immense strain on intensive care units globally. Early prediction of severe disease enables clinicians to avoid acute respiratory distress syndrome (ARDS) development and improve management of critically ill patients. The soluble receptor of advanced glycation endproducts (sRAGE) is a biomarker shown to predict ARDS. Read More

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"Celebrating old age": an obsolete expression during the COVID-19 pandemic? Medical, social, psychological, and religious consequences of home isolation and loneliness among the elderly.

Arch Med Sci 2021 8;17(2):285-295. Epub 2020 Jun 8.

'Grigore T. Popa' University of Medicine, Iasi, Romania.

Since epidemiological arguments favouring self-isolation during the COVID-19 pandemic are widely recommended, the consequences of social isolation/loneliness of older people considered to be at higher risk for severe illness are neglected. We identified and described medical, social, psychological, and religious issues, indirectly generated by the COVID-19 lockdown. Mortality induced by SARS-CoV-2 and death from other "neglected" issues were put in balance. Read More

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The effect of body mass index on the development of acute kidney injury and mortality in intensive care unit: is obesity paradox valid?

Ren Fail 2021 Dec;43(1):543-555

Department of Anesthesiology and Reanimation, Health Sciences University, Bakırköy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Background: The conflicting results of studies on intensive care unit (ICU) mortality of obese patients and obese patients with acute kidney injury (AKI) reveal a paradox within a paradox. The aim of this study was to determine the effects of body mass index and obesity on AKI development and ICU mortality.

Methods: The 4,459 patients treated between January 2015 and December 2019 in the ICU at a Tertiary Care Center in Turkey were analyzed retrospectively. Read More

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December 2021

Prospective model for predicting renal recovery in cardiac surgery patients with acute kidney injury requiring renal replacement therapy.

Nephrology (Carlton) 2021 Mar 20. Epub 2021 Mar 20.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

Aim: To develop a model for predicting renal recovery in cardiac surgery patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT).

Methods: Data from a prospective randomized controlled trial, conducted in a tertiary hospital to compare the survival effect of two dosages of hemofiltration for continuous RRT in cardiac surgery patients between 20 March 2012 and 9 August 2015, were used to develop the model. The outcome was renal recovery defined as alive and dialysis-free 90 days after RRT initiation. Read More

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The presence of liver cirrhosis is a strong negative predictor of survival for patients admitted to the intensive care unit - Cirrhosis in intensive care patients.

Z Gastroenterol 2021 Mar 16. Epub 2021 Mar 16.

Department of Internal Medicine 1, Goethe-University Hospital Frankfurt.

Background And Aims:  Liver cirrhosis is a systemic disease that substantially impacts the body's physiology, especially in advanced stages. Accordingly, the outcome of patients with cirrhosis requiring intensive care treatment is poor. We aimed to analyze the impact of cirrhosis on mortality of intensive care unit (ICU) patients compared to other frequent chronic diseases and conditions. Read More

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Incidence, Predictors, and Impact of Postoperative Acute Kidney Injury Following Fontan Conversion Surgery in Young Adult Fontan Survivors.

Semin Thorac Cardiovasc Surg 2021 Mar 7. Epub 2021 Mar 7.

Division of Cardiology, Ann & Robert H Lurie Children's Hospital of Chicago, Department of Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Acute kidney injury (AKI) is a common complication following single ventricle congenital heart surgery. Data regarding AKI following Fontan conversion (FC) surgery are limited. This study evaluated the incidence, predictors of, and prognostic value of AKI following FC. Read More

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Infrequent use of nighttime dialysis for emergency admission due to worsening heart failure in patients on maintenance hemodialysis.

Ther Apher Dial 2021 Mar 8. Epub 2021 Mar 8.

Department of Cardiovascular Medicine, Nephrology and Neurology, University of the Ryukyus School of Medicine, Okinawa, Japan.

In the emergency admission due to worsening heart failure (HF) in patients on maintenance hemodialysis, emergent dialysis may be indicated, which increases personnel expenses. To clarify the characteristics and in-hospital management of the patients, we conducted a multicenter retrospective study including 142 patients on maintenance hemodialysis emergently admitted for worsening HF (71.6 ± 9. Read More

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Association of Race with In-Hospital and Post-Hospitalization Mortality in Patients with Acute Kidney Injury.

Nephron 2021 3;145(3):214-224. Epub 2021 Mar 3.

Department of Medicine, University of Virginia, Charlottesville, Virginia, USA,

Introduction: Acute kidney injury (AKI) is known to be associated with increased mortality, and racial differences in hospital mortality exist in patients with AKI. However, it remains to be seen whether racial differences exist in post-hospitalization mortality among AKI patients.

Methods: We analyzed data of adult AKI patients admitted to the University of Virginia Medical Center between January 1, 2001, and December 31, 2015, to compare in-hospital and post-hospitalization mortality among hospitalized black and white patients with AKI. Read More

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Telehealth's New Horizon: Providing Smart Hospital-Level Care in the Home.

Telemed J E Health 2021 Mar 3. Epub 2021 Mar 3.

William Perry Center for Hemispheric Defense Studies, National Defense University, Washington, District of Columbia, USA.

During the COVID-19 pandemic, medical providers have expanded telehealth into daily practice, with many medical and behavioral health care visits provided remotely over video or through phone. The telehealth market was already facilitating home health care with increasing levels of sophistication before COVID-19. Among the emerging telehealth practices, telephysical therapy; teleneurology; telemental health; chronic care management of congestive heart failure, chronic obstructive pulmonary disease, diabetes; home hospice; home mechanical ventilation; and home dialysis are some of the most prominent. Read More

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Timing of renal replacement therapy for patients with acute kidney injury: A systematic review and meta-analysis.

J Intensive Care Soc 2021 Feb 6;22(1):67-77. Epub 2020 Feb 6.

Academic Unit of Anaesthesia, Pain and Critical Care, University of Glasgow, Glasgow, UK.

Background: Acute kidney injury is associated with high mortality, and the optimal time to start renal replacement therapy for acute kidney injury is unknown despite several randomised controlled trials on the subject. We performed a systematic review and meta-analysis to assess the effect of earlier initiation of renal replacement therapy for acute kidney injury on mortality and reported secondary outcomes.

Methods: All literature in databases EMBASE, MEDLINE and CENTRAL was searched from January 1970 to March 2019 using terms related to renal replacement therapy, timing and randomised controlled trials. Read More

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February 2021

Clinical Characteristics and Short-Term Outcomes of Chronic Dialysis Patients Admitted for COVID-19 in Metro Manila, Philippines.

Int J Nephrol Renovasc Dis 2021 17;14:41-51. Epub 2021 Feb 17.

Division of Nephrology, Department of Medicine, Philippine General Hospital, Manila, Metro Manila, Philippines.

Aim: Data published on COVID-19 in the Filipino population, particularly those with end stage kidney disease (ESKD) are still lacking.

Methods: We performed a retrospective, observational study of 68 ESKD patients admitted with COVID-19 infection at a tertiary hospital in Metro Manila, Philippines from April 1, 2020 to July 31, 2020. We compared the clinical features, baseline laboratory data, treatment strategies and short-term outcomes between those who survived and those who died. Read More

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February 2021

Surgical outcomes during COVID-19 pandemic in a third level social security hospital in southeast Mexico.

Arch Med Res 2021 Jan 22. Epub 2021 Jan 22.

IMSS UMAE Hospital Especialidades 14 "Adolfo Ruiz Cortines" Veracruz, Mexico.

Background: In December 2019, an outbreak of a novel coronavirus (COVID-19) occurred in China and became pandemic in March 2020. Patients undergoing surgery are a vulnerable risk of COVID-19 exposure/infection. The aim of the study was to determine the characteristics and outcomes of patients undergoing surgery during the COVID-19 pandemic in a third level reference hospital in Mexico. Read More

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January 2021

The timing of continuous renal replacement therapy initiation in sepsis-associated acute kidney injury in the intensive care unit: the CRTSAKI Study (Continuous RRT Timing in Sepsis-associated AKI in ICU): study protocol for a multicentre, randomised controlled trial.

BMJ Open 2021 02 19;11(2):e040718. Epub 2021 Feb 19.

Intensive Care Unit, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

Introduction: Acute kidney injury (AKI) is one of the most common organ dysfunction in sepsis, and increases the risk of unfavourable outcomes. Renal replacement therapy (RRT) is the predominant treatment for sepsis-associated AKI (SAKI). However, to date, no prospective randomised study has adequately addressed whether initiating RRT earlier will attenuate renal injury and improve the outcome of sepsis. Read More

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February 2021

Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trial.

Trials 2021 Feb 11;22(1):131. Epub 2021 Feb 11.

Hôpital de Hautepierre, Service d'Anesthésie-Réanimation et Médecine Péri-Opératoire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.

Objectives: The main objective of this study is to evaluate the effect of intravenous lidocaine on gas exchange and inflammation in acute respiratory distress syndrome due or not to Covid-19 pneumonia.

Trial Design: This is a prospective monocentric, randomized, quadruple-blinded and placebo-controlled superiority trial. This phase 3 clinical study is based on two parallel groups received either intravenous lidocaine 2% or intravenous NaCl 0. Read More

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February 2021

Altered mental status is an independent predictor of mortality in hospitalized COVID-19 patients.

Ir J Med Sci 2021 Feb 10. Epub 2021 Feb 10.

Department of Neurology, Medical College of Georgia, Augusta, GA, USA.

Background/aims: Limited data exists on the outcomes of COVID-19 patients presenting with altered mental status (AMS). Hence, we studied the characteristics and outcomes of hospitalized COVID-19 patients who presented with AMS at our hospital in rural southwest Georgia.

Methods: Data from electronic medical records of all hospitalized COVID-19 patients from March 2, 2020, to June 17, 2020, were analyzed. Read More

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February 2021