14,636 results match your criteria venous insufficiency

[The efficacy of antioxidant treatment with mexidol forte in 250 patients with chronic cerebral venous insufficiency].

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(3):57-63

Pirogov Russian National Research Medical University, Moscow, Russia.

Objective: To study the efficacy and safety of complex treatment with 2-ethyl-3-hydroxy-6-methylpyridine (mexidol forte 250) and venotonic drugs L-lysine aescinat and diosmin/hesperidin in patients with chronic cerebral venous insufficiency (CCVI).

Material And Methods: One hundred and twenty CCVI patients with clinical and ultrasonic signs of cerebral venous discirculation were studied. Patients were stratified into group 1 (=40) treated perorally with mexidol forte 250 and diosmin/hesperidin during 74 days in combination with two courses of L-lysine aescinat intravenously on the 1 and 30 days from baseline, group 2 (=40) treated with mexidol forte 250 and diosmin/hesperidin during 74 days, group 3 (=40) treated perorally with diosmin/hesperidin during 74 days. Read More

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A novel 125I seeds fixed on gastric tube for treatment of inoperable esophageal carcinoma: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25410

Department of Cardiothoracic Surgery, First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.

Abstract: To explore the treatment benefit of 125I seeds fixed on a gastric tube in the early inoperable esophageal carcinoma (EC).Three senile patients with early inoperable EC who were treated with brachytherapy between October 2017 and February 2019 were included in this study. 125I seeds were fixed on the gastric tube, which was then inserted on the surface of the EC. Read More

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Vascular Disease Patient Information Page: Compression therapy.

Vasc Med 2021 Apr 8:1358863X211002263. Epub 2021 Apr 8.

Johns Hopkins Center for Vascular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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[Pharmacological correction of total venous reflux in patients with varicose veins].

Angiol Sosud Khir 2021 ;27(1):84-89

Department of Pathological Anatomy, Altai State Medical University under the RF Ministry of Public Health, Barnaul, Russia.

Aim: To evaluate the efficacy of a micronized purified flavonoid fraction in patients with primary venous disease. The study enrolled 31 patients, with varicose veins observed in a total of 47 lower extremities which were divided into 3 groups depending on the CEAP clinical class. The group of class C2 included 19 limbs, with the groups of C3 and C4 comprising 14 limbs each. Read More

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[Efficacy of apixaban in prevention of haemorrhagic complications in treatment of deep vein thromboses with endovascular techniques].

Angiol Sosud Khir 2021 ;27(1):33-38

Department of X-ray Surgical Methods of Diagnosis and Treatment, Orel Regional Clinical Hospital, Orel, Russia.

Purpose: This study was undertaken to investigate efficacy of apixaban in prevention of haemorrhagic complications during treatment of proximal thromboses of deep veins of the lower extremities using endovascular techniques.

Patients And Methods: We retrospectively studied the results of treating a total of 50 patients presenting with deep vein thromboses at late stages of the pathological process. The patients were subdivided into 2 statistically homogeneous groups. Read More

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Ann Vasc Surg 2021 Apr 3. Epub 2021 Apr 3.

Istanbul Medipol University Faculty of Medicine, Department of Cardiovascular Surgery.

Background: There are various other collaterals draining into the venous system around the saphenofemoral junction in addition to the great saphenous vein. We aimed to determine the efficiency of prophylactic ablation of tributary veins in long term varicose vein and symptom recurrence.

Methods: Two hundred and sixty three consecutive patients whom underwent radiofrequency ablation therapy for the treatment of superficial venous reflux disease were investigated. Read More

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Aortic pathology during COVID -19 pandemics: Clinical reports in literature and open questions on the two co-occurring conditions.

Ann Vasc Surg 2021 Apr 3. Epub 2021 Apr 3.

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

Introduction: Cardiovascular involvement in SARS-CoV-2 infection has emerged as one of viral major clinical features during actual pandemic; limb arterial ischemic events, venous thrombosis, acute myocardial infection and stroke have occurred in patients. Acute aortic conditions have also been described, followed by interesting observations on cases, hypothesis, raised since the emergence of the pandemics.

Methods: a review of cases in literature of aortic pathology in patients with clinically suspected/microbiologically confirmed COVID-19 infection has been carried out to analyze anagraphic data, clinical presentation, treatment options and outcome. Read More

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Thrombus Extension After Great Saphenous Vein Mechanochemical Ablation.

Ann Vasc Surg 2021 Apr 3. Epub 2021 Apr 3.

Division of Vascular Surgery, Department of Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA. Electronic address:

Objective: To examine factors associated with thrombus extension after early experience with mechanochemical ablation, which combines mechanical damage to the venous endothelium with infusion of a sclerosant.

Methods: A retrospective review was performed of patients who underwent mechanochemical ablation to treat saphenous vein insufficiency in the thigh including the saphenofemoral junction. Data abstracted included patient demographics, procedural details, and post-procedural outcomes. Read More

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Clinical outcomes and overview of dedicated venous stents for management of chronic iliocaval and femoral deep venous disease.

Vascular 2021 Apr 4:1708538121989860. Epub 2021 Apr 4.

Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, London, UK.

Objectives: Venous stenting of the lower extremities has grown in popularity and is now considered a key component of the primary treatment strategy for the management of pathologically obstructive or stenotic lesions of the deep venous system. This review aims to provide an overview of the role of venous stenting in the management of chronic conditions affecting the deep venous system of the lower limbs.

Methods: An overview of venous stents design and current role of stenting procedure in individuals presenting with Chronic Venous Insufficiency (CVI) and presenting the current trials of dedicated venous stenting in management of chronic deep venous lesions. Read More

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Adjuvant radiofrequency thermocoagulation improves the outcome of liquid sclerotherapy in the treatment of spider veins of the leg: A pilot study.

Phlebology 2021 Apr 4:2683555211006534. Epub 2021 Apr 4.

Cardiovascular Surgery, Ministry of Health Ankara City Hospital, Ankara, Turkey.

Objective: This study evaluated the effect of low-energy radiofrequency thermocoagulation added to standard liquid sclerotherapy on clinical outcomes of patients with venous insufficiency.

Patients And Method: We included 111 patients with spider veins CEAP/C1 stage. The patients were randomized into sclerotherapy (Group 1) and sclerotherapy + sclerotherapy immediately followed by low energy percutaneous RF thermocoagulation (Group 2) groups and followed up with same protocols prospectively. Read More

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Serious adverse events and 30-day hospital readmission rate following elective total knee arthroplasty: a systematic review and meta-analysis.

J Orthop Surg Res 2021 Mar 31;16(1):236. Epub 2021 Mar 31.

Department of Orthopedic Surgery, Louisiana State University Medical Center, New Orleans, LA, USA.

Background: Elective total knee arthroplasty (TKA) is a common surgery which has evolved rapidly. However, there are no recent large systematic reviews of serious adverse event (SAE) rate and 30-day readmission rate (30-dRR) or an indication of whether surgical methods have improved.

Methods: To obtain a pooled estimate of SAE rate and 30-dRR following TKA, we searched Medline, Web of Science, Cochrane Library, and Google Scholar databases. Read More

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Prehospital emergency medical technicians can perform ultrasonography and blood analysis in prehospital evaluation of patients with chronic obstructive pulmonary disease: a feasibility study.

BMC Health Serv Res 2021 Mar 31;21(1):290. Epub 2021 Mar 31.

The Prehospital Research Unit, Region of Southern Denmark, Odense University Hospital, Odense, Denmark.

Introduction: Crowding of the emergency departments is an increasing problem. Many patients with an exacerbation of chronic obstructive pulmonary disease (COPD) are often treated in the emergency departments for a very short period before discharged to their homes. It is possible that this treatment could take place in the patients' homes with sufficient diagnostics supporting the treatment. Read More

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Development, validation and application of clinical simulation scenarios for assessment of stomatherapy specialists.

Rev Bras Enferm 2021 24;74(1):e20200360. Epub 2021 Mar 24.

Universidade Estadual de Campinas. Campinas, São Paulo, Brazil.

Objectives: to build and validate three clinical simulation scenarios and report the application with candidates for the specialist's degree in stomatherapy.

Methods: methodological study, building three scenarios and evaluation checklists; content validation with judges, using content validity index and Modified Kappa Coefficient; pre-test and application.

Results: scenarios built based on nursing care for: 1. Read More

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Use of Sponge-Foam Inserts in Compression Bandaging of Non-Healing Venous Leg Ulcers.

Ann Vasc Dis 2021 Mar;14(1):46-51

Department of Plastic and Reconstructive Surgery, Juntendo University School of Medicine, Sapporo, Hokkaido, Japan.

Venous leg ulcers (VLUs) caused by chronic venous insufficiency are difficult to treat. Outcomes after compression therapy and the current standard of care often used in conjunction with other options vary widely. We examined the effects of foam inserts on sub-bandage pressures in patients with VLUs and compared use of foam inserts in elastic and inelastic compression bandaging. Read More

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Micro-arteriovenous fistula in patients with lower limb lymphedema.

Arch Plast Surg 2021 Mar 15;48(2):219-223. Epub 2021 Mar 15.

Department of Plastic and Reconstructive Surgery, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.

Background: A micro-arteriovenous fistula (AVF) is a minute, short shunt between an artery and a vein that does not pass through a capillary. We investigated the association between micro-AVFs and lymphedema using computed tomography angiography (CTA) and venous blood gas analysis.

Methods: In 95 patients with lower limb lymphedema, the presence or absence of early venous return (EVR) was compared between patients with primary and secondary lymphedema. Read More

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Utility of high-frequency ultrasound in assessing cutaneous edema in venous ulcer patients.

Skin Res Technol 2021 Mar 25. Epub 2021 Mar 25.

Department of Dermatology and STD, JIPMER, Puducherry, India.

Background: High-frequency ultrasound (HFUS) using a 20 MHz probe is a non-invasive assessment tool. Its utility in dermatology for diagnosis of disease or for monitoring of treatment response in various dermatological conditions is still being explored. Edema secondary to venous hypertension is the main pathogenic factor in the development of venous leg ulcers. Read More

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Defining the human and health care costs of chronic venous insufficiency.

Semin Vasc Surg 2021 Mar 3;34(1):59-64. Epub 2021 Feb 3.

Division of Vascular and Endovascular Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Wang 440, Boston, MA 02114. Electronic address:

Chronic venous insufficiency (CVI) affects more than 25 million adults in the United States alone, and more 6 million with advanced stages of venous disease. The high incidence of CVI and the increasing costs of care, place a heavy financial burden on the US health care system. Recent studies estimate the total cost of care at more than $3 billion per year. Read More

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Medical Management of Heparin-Induced Thrombocytopenia Causing Acute Adrenal Insufficiency.

Cureus 2021 Feb 16;13(2):e13374. Epub 2021 Feb 16.

Critical Care Medicine, The Brooklyn Hospital Center, Brooklyn, USA.

Heparin-induced thrombocytopenia is an immune-mediated reaction to heparin and heparin analogs, which results in an acquired hypercoagulability syndrome resulting in paradoxical arterial and venous thrombosis leading to thrombocytopenia. Organs with high vascularity, such as the adrenal glands, are at an increased risk of injury in heparin-induced thrombocytopenia due to thrombus formation in the adrenal vein causing adrenal insufficiency. The standard of treatment remains discontinuation of heparin and heparin analogs and starting corticosteroids and non-heparin antithrombotic therapy such as argatroban. Read More

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February 2021

Endovascular and medical therapy of May-Thurner syndrome: Case series and scoping literature review.

J Med Vasc 2021 Apr 5;46(2):80-89. Epub 2021 Mar 5.

Surgery Department, Vascular Surgery Service, Hospital Fundación Valle del Lili, Cali, CO, Colombia. Electronic address:

Introduction: May-Thurner syndrome has been recognized as a cause of chronic venous insufficiency and a trigger for venous thromboembolism. There is no consensus about the definition, diagnosis, and therapeutic approach. We are aiming to describe its characteristics and a scoping literature review. Read More

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Prospective comparative study evaluating the role of flavonoids after endovenous thermal ablation.

Phlebology 2021 Mar 22:2683555211002331. Epub 2021 Mar 22.

Department of Vascular Surgery, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Objectives: The aim of our study was to evaluate the role of flavonoids in the improvement of post-operative symptoms after endovenous thermal ablation (EVTA).

Methods: A prospective comparative study of 120 consecutive patients undergoing EVTA of the greater saphenous vein associated with phlebectomies was undertaken. Patients were grouped in those receiving micronized purified flavonoid fraction (MPFF- 60 patients) agent 500 mg Bid 7 days pre- and 30 days post- operatively (MPFF group) and those in the control group (60 patients) who did not. Read More

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Normotensive presentation in primary aldosteronism: A report of two cases.

J Renin Angiotensin Aldosterone Syst 2021 Jan-Dec;22(1):14703203211003780

Department of Endocrinology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Normotensive patients with primary aldosteronism (PA) are relatively rare. Herein, we report two patients with normotensive PA and present a literature review to improve an understanding of the disease. Patient 1, a 56-year-old man, presented with recurrent hypokalemia that lasted for more than 2 years. Read More

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Hemolysis in patients with Extracorporeal Membrane Oxygenation therapy for severe Acute Respiratory Distress Syndrome - a systematic review of the literature.

Int J Med Sci 2021 18;18(8):1730-1738. Epub 2021 Feb 18.

Department of Anesthesiology and Operative Intensive Care Medicine CCM/CVK, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health.

The Acute Respiratory Distress Syndrome (ARDS) is common in patients on the Intensive Care Unit and associated with significant mortality rates. In situations of severe respiratory insufficiency and failure of all possible conservative therapeutic approaches, veno-venous extracorporeal membrane oxygenation (VV ECMO) is used as a final option for temporary replacement of pulmonary function. ARDS as well as sepsis and VV ECMO treatment are all associated with intravascular hemolysis. Read More

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February 2021

Pelvic venous insufficiency secondary to iliac vein stenosis and ovarian vein reflux treated with iliac vein stenting alone.

J Vasc Surg Venous Lymphat Disord 2021 Mar 18. Epub 2021 Mar 18.

Center for Vascular Medicine, 1600 Crain Hwy South, Suite 409, Glen Burnie, MD, 21061; Center for Vein Restoration, 7474 Greenway Drive, Suite 1000, Greenbelt, Maryland, 20770. Electronic address:

Introduction: We have previously reported that in women with pelvic venous disorders (PeVD) secondary to pelvic venous insufficiency (PVI), 56% present with an iliac vein stenosis (IVS) and ovarian vein reflux (OVR). The purpose of this investigation is to determine if women with combined disease can be treated with iliac vein stenting alone.

Methods: A retrospective review of prospectively collected data at the Center for Vascular Medicine was performed. Read More

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Evaluation of physical activity level and exercise capacity in patients with varicose veins and chronic venous insufficiency.

Phlebology 2021 Mar 21:2683555211002339. Epub 2021 Mar 21.

Department of Cardiovascular Surgery, Dr. Nafiz Körez Sincan Public Hospital, Ankara, Turkey.

Objective: The clinical indication of chronic venous insufficiency (CVI) is related to functional performance and the benefits of physical activity in patients with CVI are known. Despite its importance, the literature is limited in this regard. This study aimed to determine exercise capacity and physical activity level in patients with varicose veins and CVI. Read More

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A Case Report on Treatment of Nonhealing Leg Ulcer: Do Not Forget the Underlying Disease.

Int J Low Extrem Wounds 2021 Mar 20:1534734621999029. Epub 2021 Mar 20.

University of Campania "Luigi Vanvitelli", Naples, Italy.

Prevalence of nonhealing ulcers of lower extremities has increased over years causing heavy health, social, and economic burdens. Chronic ulcers are difficult to treat since they require tailored multistep treatment and patient compliance. To treat chronic wounds successfully, clinicians must keep in mind the ulcer etiology as well as the underlying diseases. Read More

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Limitations to self-management of adjustable compression wraps in the elderly: results of a prospective cohort study.

Int Angiol 2021 Mar 19. Epub 2021 Mar 19.

Private Practitioner, Marseille, France.

Background: Adjustable compression wraps are used for treating lymphedema and chronic venous insufficiency. These diseases often affect elderly patients with associated pathologies or other limiting factors. These can prevent the self-application of the device by patients on themselves. Read More

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Modified compression therapy in mixed arterial-venous leg ulcers: An integrative review.

Int Wound J 2021 Mar 18. Epub 2021 Mar 18.

FRCS Wound Healing Research Unit, Cardiff University, Cardiff, UK.

Leg ulcers remain an increased burden to healthcare cost and morbidity in modern society. While most leg ulcers are venous in origin, recognition and prompt identification of concomitant arterial occlusive disease is critical to determine underlying aetiology and subsequent management. This integrative review presents the current evidence to establish the role of modified compression therapy (MCT) in treatment of mixed arterial venous leg ulcers (MAVLU). Read More

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Insulin Dependence Increases the Risk of Complications and Death in Total Joint Arthroplasty: A Systematic Review and Meta-(Regression) Analysis.

Orthop Surg 2021 Mar 18. Epub 2021 Mar 18.

Department of Orthopaedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.

Objectives: To investigate the proportion of insulin-dependent diabetes mellitus (IDDM) patients among diabetic patients undergoing total joint arthroplasty (TJA) and whether insulin dependence is associated with postoperative complications.

Methods: A systematic literature search was performed in EMBASE, PubMed, Ovid, Medline, the Cochrane Library, Web of Science, the China Science and Technology Journal Database, and China National Knowledge Infrastructure from the inception dates to 10 September 2019. Observational studies reporting adverse events with IDDM following TJA were included. Read More

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Wound cleansing for treating venous leg ulcers.

Cochrane Database Syst Rev 2021 03 10;3:CD011675. Epub 2021 Mar 10.

School of Nursing & Midwifery, Royal College of Surgeons in Ireland, Dublin, Ireland.

Background: Leg ulcers are open skin wounds that occur below the knee but above the foot. The majority of leg ulcers are venous in origin, occurring as a result of venous insufficiency, where the flow of blood through the veins is impaired; they commonly arise due to blood clots and varicose veins. Compression therapy, using bandages or stockings, is the primary treatment for venous leg ulcers. Read More

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