4 results match your criteria venosa blume

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Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit.

Phytother Res 2017 Sep 13;31(9):1357-1368. Epub 2017 Jul 13.

Health Science North Research Institute, 41 Ramsey Lake Road, Sudbury, ON, P3E 5J1, Canada.

Extracts from the tubers of Stephania venosa (Blum) Spreng growing in Vietnam significantly inhibited cell proliferation against a number of cancer cells including HeLa, MDA-MB231 and MCF-7 cells. A bioassay-guided fractionation led to the isolation of four aporphine and one tetrahydroprotoberberine alkaloids: dehydrocrebanine 1, tetrahydropalmatine 2, stephanine 3, crebanine 4 and O-methylbulbocapnine 5. The characterization of these compounds was based on MS, NMR and published data. Read More

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September 2017

Acetylcholinesterase Inhibitory Activity of Alkaloids Isolated from Stephania venosa.

Nat Prod Commun 2016 Dec;11(12):1805-1806

Stephania venosa (Blume) Spreng or "Sa-Bu-Leud" is a Thai medicinal plant used for treatment of cancer and diabetes, and as a blood-tonic and aphrodisiac. This plant .ontains alkaloids as its major components and has been of interest for its acetylcholinesterase (AChE) inhibitory activity. Read More

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December 2016

Acetylcholinesterase inhibitory activity of Thai traditional nootropic remedy and its herbal ingredients.

J Med Assoc Thai 2011 Dec;94 Suppl 7:S183-9

Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Rangsit Campus, Pathumtani, Thailand.

The incidence of Alzheimer disease (AD) is increasing every year in accordance with the increasing of elderly population and could pose significant health problems in the future. The use of medicinal plants as an alternative prevention or even for a possible treatment of the AD is, therefore, becoming an interesting research issue. Acetylcholinesterase (AChE) inhibitors are well-known drugs commonly used in the treatment of AD. Read More

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December 2011

Cytotoxic and antimicrobial activities of aporphine alkaloids isolated from Stephania venosa (Blume) Spreng.

Planta Med 2011 Sep 8;77(13):1519-24. Epub 2011 Feb 8.

Chulabhorn Research Institute, Bangkok, Thailand.

The cytotoxic activity of five alkaloids, namely 4,5-dioxo-dehydrocrebanine (1), dehydrocrebanine (2), crebanine (3), oxostephanine (4), and thailandine (5) isolated from the tuber and leaves of Stephania venosa (Blume) Spreng was investigated. Thailandine showed the strongest activity against lung carcinoma cells (A549) (IC50 of 0.30 µg/mL) with very low cytotoxicity against normal embryonic lung cells (MRC-5). Read More

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September 2011
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