14,639 results match your criteria venezuela [10]


Synthesis, crystal structure, Hirshfeld surface analysis and energy framework calculations of -3,7,9,9-tetra-methyl-10-(prop-2-yn-1-yl)-1,2,3,4,4a,9,9a,10-octa-hydro-acridine.

Acta Crystallogr E Crystallogr Commun 2021 Mar 5;77(Pt 3):226-232. Epub 2021 Feb 5.

Laboratorio de Cristalografía-LNDRX, Departamento de Química, Facultad de Ciencias, Universidad de los Andes, Mérida, Venezuela.

The title heterocyclic compound, CHN, has been prepared in good yield (72%) a BiCl-catalyzed cationic Povarov reaction between -propargyl-4-methyl-aniline and (±)-citronellal. The X-ray single-crystal study indicates that the structure consists of mol-ecules connected by C-H⋯π contacts to produce chains, which pack in a sandwich-herringbone fashion along the -axis direction. Hirshfeld surface analysis indicates that H⋯H inter-actions dominate by contributing 79. Read More

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Human papillomavirus and Chlamydia trachomatis in oral and genital mucosa of women with normal and abnormal cervical cytology.

BMC Infect Dis 2021 May 5;21(1):422. Epub 2021 May 5.

Facultad de Ciencias Médicas, Instituto de Virología "Dr. J. M. Vanella", Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n- Ciudad Universitaria, ZP: 5016, Córdoba, Argentina.

Background: HPV and C.trachomatis are the most prevalent, viral and bacterial STI worldwide. Both commonly have an asymptomatic development and can evolve into a persistent infection which, added to coinfections, may be important cofactors for the oncogenic transformation. Read More

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Predictors of patient safety culture in hospitals in Venezuela: A cross-sectional study.

Medicine (Baltimore) 2021 May;100(18):e25316

Methodology of Biomedical Research and Public Health programme. Universitat Autonoma de Barcelona.

Abstract: An organization's culture with regard to patient safety is important because it defines the beliefs and practices of the organization, and consequently its efficiency and productivity.Knowing the level of this and the factors that influence or not their dynamic represents a challenge, due to the degree of complexity and specificity of the elements involved.The aim of this study was to analyze predictors of patient safety culture in public and private hospitals and examining the factors that contribute to it, constructing a new and specific theoretical and methodological model. Read More

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Cone-beam computed tomography evaluation of C-shaped root and canal morphology of mandibular premolars.

BMC Oral Health 2021 May 4;21(1):236. Epub 2021 May 4.

Postgraduate Department of Endodontics, Universidad Central de Venezuela, Caracas, Venezuela.

Background: Mandibular premolars are complicated teeth to endodontically treat due to the anatomical variations that can present. The purpose of this study was to determine the presence of C-shaped configurations in mandibular premolars by cone-beam computed tomography (CBCT).

Methods: 380 mandibular first premolars and 308 mandibular second premolars cone-beam computed tomographic images were obtained from 292 patients (175 female and 117 male). Read More

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Population genomics provides insights into the evolution and adaptation to humans of the waterborne pathogen Mycobacterium kansasii.

Nat Commun 2021 05 3;12(1):2491. Epub 2021 May 3.

Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Medical College and School of Basic Medical Sciences, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.

Mycobacterium kansasii can cause serious pulmonary disease. It belongs to a group of closely-related species of non-tuberculous mycobacteria known as the M. kansasii complex (MKC). Read More

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HUMAN COSAVIRUS INFECTION IN HIV SUBJECTS WITH DIARRHOEA: PERSISTENT DETECTION ASSOCIATED WITH FATAL OUTCOME.

J Clin Virol 2021 Apr 16;139:104825. Epub 2021 Apr 16.

Servicio de Infectología. Hospital General del Oeste "Dr. José Gregorio Hernández". Catia, Sector Los Magallanes de Catia. Caracas, Venezuela.

Background: Human cosavirus (HCoSV) is a new member of the Picornaviridae family, geographically widespread among humans. It has been suggested as a causative agent of acute gastroenteritis, but its pathogenicity is not currently certain. In HIV-infected subjects, diarrhoea is one of the most frequent gastrointestinal manifestations, whose aetiology remains often unexplained. Read More

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Palliative medicine specialization in Latin America: A comparative analysis.

J Pain Symptom Manage 2021 Apr 29. Epub 2021 Apr 29.

Dieter Scheffner Center for Medical Education and Educational Research, Dean´s Office of Study Affairs, Charité - Universitätsmedizin Berlin.

Background: Formal recognition of palliative medicine as a specialty has been one of the main drivers in the development of palliative care.

Aim: To provide a comparative, comprehensive overview on the status of palliative medicine as medical specialty across Latin America.

Method: We conducted a comparative study of 19 Latin American countries. Read More

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Validation of the LupusQoL in Venezuela: A Specific Measurement of Quality of Life in Patients with Systemic Lupus Erythematosus.

Reumatol Clin 2021 Apr 27. Epub 2021 Apr 27.

Escuela de Ciencias de la Salud «Dr. Francisco Battistini Casalta», Universidad de Oriente-Núcleo Bolívar, Ciudad Bolívar, Venezuela; Centro Clínico Universitario de Oriente, Ciudad Bolívar, Venezuela.

Background And Objectives: Traditionally, the health-related quality of life (HRQoL) of patients with systemic lupus erythematosus (SLE) has been assessed using instruments that neglect the specific characteristics of the disease. This study determines the validity of the Lupus Quality of Life (LupusQoL) questionnaire as a psychometrically stable instrument to measure the HRQoL of patients with SLE in Venezuela and establishes the cutoff points of the questionnaire for the Venezuelan population.

Patients And Methods: A cross-sectional study was conducted that included patients with SLE from April to July 2018. Read More

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Synthesis of 5H-indeno[1,2-b]pyridine derivatives: Antiproliferative and antimetastatic activities against two human prostate cancer cell lines.

Arch Pharm (Weinheim) 2021 Apr 30:e2100092. Epub 2021 Apr 30.

Organic Synthesis Laboratory, Faculty of Pharmacy, Central University of Venezuela, Caracas, Venezuela.

This study describes the direct synthesis of 2-amino-4-(phenylsubstituted)-5H-indeno[1,2-b]pyridine-3-carbonitrile derivatives 5-21, through sequential multicomponent reaction of aromatic aldehydes, malononitrile, and 1-indanone in the presence of ammonium acetate and acetic acid (catalytic). The biological study showed that compound 10 significantly impeded proliferation of the cell lines PC-3, LNCaP, and MatLyLu. The antimetastatic effects of compound 10 could be related with inhibition of MMP9 in the PC-3 and LNCaP human cell lines. Read More

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Global policy for assisted colonization of species.

Science 2021 Apr;372(6541):456-458

School of Earth and Environmental Sciences, The University of Queensland, St Lucia, QLD, Australia.

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Disturbance Modelling for Minimum Variance Control in Adaptive Optics Systems Using Wavefront Sensor Sampled-Data.

Sensors (Basel) 2021 Apr 27;21(9). Epub 2021 Apr 27.

Departamento Electrónica, Universidad Técnica Federico Santa María (UTFSM), Av. España 1680, Valparaíso 2390123, Chile.

Modern large telescopes are built based on the effectiveness of adaptive optics systems in mitigating the detrimental effects of wavefront distortions on astronomical images. In astronomical adaptive optics systems, the main sources of wavefront distortions are atmospheric turbulence and mechanical vibrations that are induced by the wind or the instrumentation systems, such as fans and cooling pumps. The mitigation of wavefront distortions is typically attained via a control law that is based on an adequate and accurate model. Read More

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Accelerometer-Measured Daily Step Counts and Adiposity Indicators among Latin American Adults: A Multi-Country Study.

Int J Environ Res Public Health 2021 Apr 27;18(9). Epub 2021 Apr 27.

Centro de Excelencia em Nutrição e Dificuldades Alimentaes (CENDA), Instituto Pensi, Fundação José Luiz Egydio Setubal, Hospital Infantil Sabará, São Paulo 01228-200, Brazil.

The aim of the present study was to examine the sex-related associations between accelerometer-measured daily step counts and adiposity indicators in adults from eight Latin American countries. We analyzed data from 2524 adults (aged 18-65 years) from the Latin American Study of Nutrition and Health. Device-measured daily step counts were measured by accelerometers (ActiGraph GT3X). Read More

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Nutritive Value, In Vitro Fermentation, and Methane Production of Cactus Cladodes, Sugarcane Bagasse, and Urea.

Animals (Basel) 2021 Apr 28;11(5). Epub 2021 Apr 28.

Department of Animal Science, Federal Rural University of Pernambuco, Dom Manoel de Medeiros Street, Dois Irmãos, Recife, Pernambuco 52171-900, Brazil.

This study evaluated the effect of different roughages fed to sheep on nutrient and water intake, ingestive behavior, nitrogen balance, microbial protein synthesis, fermentation parameters, and methane production using an in vitro gas production system. The treatments consisted of five diets: cactus cladodes (NUB) and (OUB), both with the addition of sugarcane bagasse (SB) and urea/ammonium sulfate (urea/as); Tifton hay (TH); corn silage (CS); and sorghum silage (SS), also with added urea/as. The NUB provided greater ( ≤ 0. Read More

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Long-Term Iron and Vitamin B12 Deficiency Are Present after Bariatric Surgery, Despite the Widespread Use of Supplements.

Int J Environ Res Public Health 2021 Apr 25;18(9). Epub 2021 Apr 25.

Department of Systems Medicine, Tor Vergata University, 00133 Rome, Italy.

There are few long-term nutritional studies in subjects undergoing bariatric surgery that have assessed weight regain and nutritional deficiencies. In this study, we report data 8 years after surgery on weight loss, use of dietary supplements and deficit of micronutrients in a cohort of patients from five centres in central and northern Italy. The study group consisted of 52 subjects (age: 38. Read More

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Association of Urinary and Plasma Levels of Trimethylamine N-Oxide (TMAO) with Foods.

Nutrients 2021 Apr 23;13(5). Epub 2021 Apr 23.

Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Tor Vergata, via Montpellier 1, 00133 Rome, Italy.

Introduction: Trimethylamine N-oxide (TMAO) may play a key mediator role in the relationship between the diet, gut microbiota and cardiovascular diseases, particularly in people with kidney failure. The aim of this review is to evaluate which foods have a greater influence on blood or urinary trimethylamine N-oxide (TMAO) levels.

Methods: 391 language articles were screened, and 27 were analysed and summarized for this review, using the keywords "TMAO" AND "egg" OR "meat" OR "fish" OR "dairy" OR "vegetables" OR "fruit" OR "food" in December 2020. Read More

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Antibacterial Activity and Reversal of Multidrug Resistance of Tumor Cells by Essential Oils from Fresh Leaves, Flowers, and Stems of Schultz Bipontinus (Asteraceae) Collected in Mérida-Venezuela.

Biomolecules 2021 Apr 19;11(4). Epub 2021 Apr 19.

Organic Biomolecular Research Group, Faculty of Pharmacy and Bioanalysis, Research Institute, University of Los Andes, Mérida 5101, Venezuela.

Essential oils obtained by hydrodistillation of leaves, flowers, and stems were analyzed by GC and GC/MS techniques revealing myrcene, limonene, β-phellandrene, and sabinene among the main components. The aim of the present study was to evaluate the MDR modulator activity on human MDR1 gene transfected mouse lymphoma cell line and the antimicrobial activity on the essential oils obtained from different parts of the species under investigation. The results revealed that MQL caused a similar increase in the fluorescence activity of the cells at 0. Read More

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The Impact of a Plant-Based Diet on Gestational Diabetes: A Review.

Antioxidants (Basel) 2021 Apr 2;10(4). Epub 2021 Apr 2.

Independent Researcher, Via Venezuela 66, 98121 Messina, Italy.

Gestational diabetes mellitus (GDM) represents a challenging pregnancy complication in which women present a state of glucose intolerance. GDM has been associated with various obstetric complications, such as polyhydramnios, preterm delivery, and increased cesarean delivery rate. Moreover, the fetus could suffer from congenital malformation, macrosomia, neonatal respiratory distress syndrome, and intrauterine death. Read More

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A Comparative Analysis of Honeypots on Different Cloud Platforms.

Sensors (Basel) 2021 Apr 1;21(7). Epub 2021 Apr 1.

School of Computing Edinburgh Napier University, Edinburgh EH10 5DT, UK.

In 2019, the majority of companies used at least one cloud computing service and it is expected that by the end of 2021, cloud data centres will process 94% of workloads. The financial and operational advantages of moving IT infrastructure to specialised cloud providers are clearly compelling. However, with such volumes of private and personal data being stored in cloud computing infrastructures, security concerns have risen. Read More

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Evaluation of the diagnostic performance of nine commercial RT-PCR kits for the detection of SARS-CoV-2 in Colombia.

J Med Virol 2021 Apr 29. Epub 2021 Apr 29.

Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to the design and development of multiple reverse-transcription polymerase chain reaction kits aimed to facilitate the rapid scale-up of molecular testing for massive screening. We evaluated the diagnostic performance of nine commercial kits, which showed optimal performance and high discriminatory power. However, we observed differences in terms of sensitivity, specificity, and E gene Ct Values and discuss these results in light of the influence of SARS-CoV-2 genetic variability and its potential impact in current molecular diagnostic assays. Read More

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The 2-year rodent bioassay in drug and chemical carcinogenicity testing: Panorama of its concordance, utility, configuration, and provisional regulatory role.

J Pharmacol Toxicol Methods 2021 Apr 24:107070. Epub 2021 Apr 24.

Laboratory of Neuropeptides, Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.

For several intended uses of chemicals, the 2-year rodent bioassay (RCB) has been the benchmark method to screen the carcinogenicity to humans of substances (according to the hazard identification sphere). Despite the ongoing controversy around this traditional testing, the RCB is still in force and being used by stakeholders. After assembling the RCB's ability to forecast the carcinogenicity to humans of substances, the current review aimed to provide a discussion on the RCB's (1) sensitivity and specificity; (2) utility; (3) configuration, and (4) provisional role in the regulatory practice. Read More

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Revisiting the type of Cespitularia stolonifera/ Gohar, 1938 leads to the description of a new genus and a species of the family Xeniidae (Octocorallia, Alcyonacea).

Zootaxa 2021 Apr 22;4964(2):zootaxa.4964.2.5. Epub 2021 Apr 22.

School of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, 69978, Israel.

Because of the problematical identity and status of the type of the xeniid soft coral genus Cespitularia Milne-Edwards Haime, 1850, the species C. stolonifera Gohar, 1938 is revised. Examination of the type colonies has led to the establishment of the new genus Unomia gen. Read More

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A review of emCryphocricos/em Signoret, 1850 (Naucoridae: Cryphocricinae) with descriptions of three new species.

Authors:
Robert W Sites

Zootaxa 2021 Apr 14;4958(1):zootaxa.4958.1.7. Epub 2021 Apr 14.

Enns Entomology Museum University of Missouri Columbia, Missouri 65211 USA.

The genus Cryphocricos Signoret, 1850 was recently determined in a molecular phylogeny to be distantly related to other taxa of the subfamily Cryphocricinae to the extent that it is now once again the sole member of the subfamily. This exclusively New World group of aquatic bugs lives in fast and usually turbulent current and respires by means of a plastron. Efforts to identify morphological features to distinguish among the species have largely fallen short, and some species have been established based on features that exhibit a high degree of intraspecific variation overlapping those of other species. Read More

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Discovery of an additional piece of the large gymnophthalmid puzzle: a new genus and species of stream spiny lizard (Squamata: Gymnophthalmidae: Cercosaurinae) from the western Guiana Shield in Venezuela.

Zootaxa 2021 Mar 30;4950(2):zootaxa.4950.2.4. Epub 2021 Mar 30.

Museo de Historia Natural La Salle, Fundación La Salle de Ciencias Naturales, Caracas 1050, Distrito Capital, Venezuela.

Gymnophthalmids are a highly diverse group of Neotropical lizards and its species richness is still in process of discovery. The incorporation of molecular evidence and a noticeable increase in taxon and geographic sampling in systematic studies has led to the description of numerous new genera and species of gymnophthalmids (particularly in Cercosaurinae) in recent years. Herein we describe a new genus and species of cercosaurine lizard with crocodile-like morphology, from the Venezuelan Guiana Shield on the basis of molecular phylogenetic and morphological evidence. Read More

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Gender differences in the perception of asthma respiratory symptoms in five Latin American countries.

J Asthma 2021 Apr 26:1-18. Epub 2021 Apr 26.

Respiratory Division of EPM/Unifesp and Director of the Pulmonary Rehabilitation Center at Unifesp/EPM, Brazil.

To determine the differences between sexes in perceptions of asthma symptoms, asthma control, daily activities, and symptom exacerbation in Latin American countries. This cross-sectional study was performed using data from the Latin America Asthma Insight and Management (LA-AIM study ( = 2167) carried out in Argentina, Brazil, Mexico, Venezuela, and Puerto Rico. Face-to-face interviews were conducted, and patients orally completed a 53-question survey assessing five main domains of asthma: symptoms, impact on daily activities, disease control, exacerbation, and treatment/medication. Read More

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Worldwide prevalence of a lingual canal in mandibular premolars - a multi-center cross-sectional study with meta-analysis.

J Endod 2021 Apr 23. Epub 2021 Apr 23.

Dental Specialty Center, Brazilian Military Police, Minas Gerais, Brazil.

Introduction: The presence of multiple root canals is an important morphological aspect of mandibular premolars. This study aimed to perform a worldwide analysis on the prevalence of a lingual canal in mandibular premolars and evaluate its influence on patients' demographics of 23 countries using CBCT images.

Methods: Observers from 23 countries were instructed to evaluate CBCT images of 300 first and 300 second premolars (13,800 teeth) regarding the presence of a lingual canal, canal configuration, and data related to patients' ethnicity, age and gender, following a standardized screening methodology. Read More

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Lack of experience is a main cause of maternal death in placenta accreta spectrum patients.

Acta Obstet Gynecol Scand 2021 Apr 25. Epub 2021 Apr 25.

Clínica de Espectro de Acretismo Placentario, Fundación Valle del Lili, Cali, Colombia.

Introduction: Placenta accreta spectrum (PAS) is a serious condition with a mortality as high as 7%. However, the factors associated with this type of death have not been adequately described, with an almost total lack of publications analyzing the determining factors of death in this disease. The aim of our work is to describe the causes of death related to PAS and to analyze the associated diagnosis and treatment problems. Read More

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Strengthening breast surgery workforce capacity: implementation of competency-based training programme.

Ecancermedicalscience 2021 11;15:1203. Epub 2021 Mar 11.

Breast Unit, Caracas University Hospital, Caracas 1040, Venezuela.

Background And Rationale: Quality education is a prerequisite for building a sustainable health system. To address this requirement, it is necessary to strengthen capacity and expand the training opportunities to ensure equitable and efficient development of core professional competencies for specific contexts and educational needs.

Methods And Results: A competency-based training programme for Breast Surgeons was built and was applied based on the Consolidated Framework for Implementation Research (CFIR). Read More

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Mutations in the SARS-CoV-2 spike protein modulate the virus affinity to the human ACE2 receptor, an analysis.

EXCLI J 2021 8;20:585-600. Epub 2021 Mar 8.

Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Apdo 20632, Caracas 1020A, Venezuela.

The increasing number of SARS-CoV-2 variants associated with highly transmissible phenotypes is a health-public concern in the current pandemic scenario. Herein, we developed a comprehensive analysis of the changes occurring upon mutations in the viral spike. We focused on mutants located in the receptor-binding domain of the viral spike protein and analyzed whether these mutants modulate the interaction with the human host receptor angiotensin-converting enzyme II (ACE2). Read More

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A Case of Dysembryoplastic Neuroepithelial Tumor in an Adolescent Male.

Cureus 2021 Mar 16;13(3):e13917. Epub 2021 Mar 16.

Division of Multiple Sclerosis and Neuroimmunology, Department of Neurology, University of Texas Health Science Center at Houston, Houston, USA.

Dysembryoplastic neuroepithelial tumors (DNETs) are benign mixed glioneuronal neoplasms that frequently occur in children and young adults. We present the case of a 17-year-old male who arrived at the hospital following seizure-like activity. A magnetic resonance imaging (MRI) scan showed a 10 x 8 x 10 mm, oval-shaped, non-enhancing, well-defined mass within the right hippocampus. Read More

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Local adaptation of on the Tibetan Plateau.

Proc Natl Acad Sci U S A 2021 Apr;118(17)

Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology of the Ministry of Education/Ministry of Health/Chinese Academy of Medical Science (MOE/NHC/CAMS), Shanghai Medical College and School of Basic Medical Sciences, Shanghai Public Health Clinical Center, Fudan University, 200032 Shanghai, China;

During its global dispersal, () has encountered varied geographic environments and host populations. Although local adaptation seems to be a plausible model for describing long-term host-pathogen interactions, genetic evidence for this model is lacking. Here, we analyzed 576 whole-genome sequences of strains sampled from different regions of high-altitude Tibet. Read More

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