394,518 results match your criteria vein

Effectiveness of Microcurrent Stimulation in Preserving Retinal Function of Blind Leading Retinal Degeneration and Optic Neuropathy: A Systematic Review.

Neuromodulation 2021 May 13. Epub 2021 May 13.

Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Objectives: To systematically identify and summarize the effectiveness and the parameters of electrical stimulation (ES) for the preservation of visual function in major retinal degeneration and optic neuropathy.

Materials And Methods: A systematic review of clinical studies, using ES therapy in patients with blind leading retinal degenerations, including retinitis pigmentosa (RP), age-related macular degeneration (AMD), glaucoma, retinal vein occlusion (RVO), retinal artery occlusion (RAO), and optic neuropathy was conducted. PubMed, EMBASE, Cochrane Library, and Web of Science were searched for relevant interventional studies including randomized controlled trials (RCTs) and observational studies. Read More

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The wing venation of a new fossil species, reconstructed using geometric morphometrics, adds to the rare fossil record of Triassic Gondwanian Odonata.

Arthropod Struct Dev 2021 May 10;63:101056. Epub 2021 May 10.

Centre de Recherche en Paléontologie - Paris (CR2P), Sorbonne Université, MNHN, CNRS, 57 rue Cuvier, CP38, F-75005, Paris, France. Electronic address:

Probably the most common rock-imprint fossil-insect remain is an incomplete isolated wing. This pitfall has been traditionally addressed by manually reconstructing missing parts, which is not ideal to comprehend long-term evolutionary trends in the group, in particular for morphological diversity (i.e. Read More

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Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson.

Fitoterapia 2021 May 10:104923. Epub 2021 May 10.

Natural Product Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address:

Acmoxanthones A-E (1-5), five new lavandulylated xanthones, were isolated from the aerial parts of Hypericum acmosepalum, together with four known xanthones. Their structures with absolute configurations were elucidated on the basis of analysis of MS, NMR and chiroptical properties. A bioassay against high glucose-induced damage on human umbilical vein endothelial cells (HUVECs) showed ananixanthone (6) and osajaxanthone (7) had potential antioxidative damage activity with EC values of 10. Read More

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High-throughput fabrication of silk fibroin/hydroxypropyl methylcellulose (SF/HPMC) manofibrous scaffolds for skin tissue engineering.

Int J Biol Macromol 2021 May 10. Epub 2021 May 10.

National Engineering Laboratory for Modern Silk, College of Textile and Engineering, Soochow University, 199 Ren-ai Road, Suzhou 215123, China.

Silk fibroin (SF) is a natural macromolecule material with good biocompatibility, which can be used to prepare a variety of biological materials. In this study, hydroxypropyl methylcellulose (HPMC) was applied to improve the properties of SF nanofibrous scaffolds (NFS) for skin tissue engineering applications. SF/HPMC NFS with varying weight ratios of SF: HPMC were prepared in batches by a modified free surface electrospinning. Read More

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Racial and Ethnic Differences in Reconstructive Surgery for Apical Vaginal Prolapse.

Am J Obstet Gynecol 2021 May 10. Epub 2021 May 10.

Department of Obstetrics, Gynecology & Reproductive Science, University of California San.

Background: There is limited literature identifying racial and ethnic health disparities among surgical modalities and outcomes in the field of urogynecology and specifically pelvic organ prolapse surgery.

Objective: To evaluate differences in surgical approach for apical vaginal prolapse and postoperative complications by race and ethnicity STUDY DESIGN: This is a retrospective cohort study of women undergoing surgical repair for apical vaginal prolapse between 2014 and 2017 using data from the American College of Surgeons National Surgical Quality Improvement Program. Patients were eligible for inclusion if they underwent either a vaginal colpopexy or abdominal sacrocolpopexy (ASC). Read More

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Venous thromboembolism.

Lancet 2021 May 10. Epub 2021 May 10.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada; Department of Medicine, McGill University, Montreal, QC, Canada. Electronic address:

Venous thromboembolism, comprising both deep vein thrombosis and pulmonary embolism, is a chronic illness that affects nearly 10 million people every year worldwide. Strong provoking risk factors for venous thromboembolism include major surgery and active cancer, but most events are unprovoked. Diagnosis requires a sequential work-up that combines assessment of clinical pretest probability for venous thromboembolism using a clinical score (eg, Wells score), D-dimer testing, and imaging. Read More

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Effects of Short-Term Air Pollution Exposure on Venous Thromboembolism: A Case-Crossover Study.

Ann Am Thorac Soc 2021 May 13. Epub 2021 May 13.

University of Utah, Pulmonary and Critical Care Medicine, Salt Lake City, Utah, United States.

Rationale: Exposure to outdoor air pollution is associated with increased cardiovascular disease, respiratory illness, and mortality. The effect of air pollution on venous thromboembolism (VTE) is less certain.

Objectives: To test for associations between short-term exposure to air pollution and VTE. Read More

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Predictive factors of venous recanalization in upper-extremity vein thrombosis.

PLoS One 2021 13;16(5):e0251269. Epub 2021 May 13.

Department of Internal Medicine and Vascular Medicine, CHU de Nantes, Nantes, France.

Background: Upper extremity venous thrombosis (UEVT) represents about 10% of venous thrombo-embolic disease. This is mainly explained by the increasing use of central venous line, for oncologic or nutritional care. The factors associated with venous recanalization are not known. Read More

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The impact of genetic background and sex on the phenotype of IL-23 induced murine spondyloarthritis.

PLoS One 2021 13;16(5):e0247149. Epub 2021 May 13.

Brigham and Women's Hospital, Boston, MA, United States of America.

Background: Overexpression of IL-23 in adult mice by means of hydrodynamic tail vein injection of IL-23 minicircles has been reported to result in spondyloarthritis-like disease. The impact of genetic background and sex on the disease phenotype in this model has not been investigated.

Methods: We compared male B10. Read More

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A novel classification of portal venous tumor invasion to predict residual tumor status after surgery in patients with pancreatic neuroendocrine neoplasms.

J Cancer Res Clin Oncol 2021 May 13. Epub 2021 May 13.

Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Purpose: To elucidate whether portal venous tumor invasion (PVTI) is a prognostic factor for patients with pancreatic neuroendocrine neoplasms (Pan-NENs).

Methods: From 2002 to 2019, 240 patients with Pan-NEN were included to examine prognostic factors. PVTI based on computed tomography (CT) images are classified into four types: no PVTI (Vp0/1), PVTI not invading the superior mesenteric vein (Vp2), PVTI invading the superior mesenteric vein or portal vein (Vp3), and PVTI invading the portal bifurcation (Vp4). Read More

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Spatial Reconstruction of the Early Hepatic Transcriptomic Landscape after an Acetaminophen Overdose using Single-cell RNA Sequencing.

Toxicol Sci 2021 May 12. Epub 2021 May 12.

Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.

An acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States. A hallmark characteristic of APAP hepatotoxicity is centrilobular necrosis. General, innate mechanisms such as lower amounts of GSH and higher Cyp2e1 expression in pericentral (PC) hepatocytes are known to contribute to the differences in susceptibility to cell injury between periportal (PP) hepatocytes and PC hepatocytes. Read More

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Association between functional mitral regurgitation and recurrence of paroxysmal atrial fibrillation following catheter ablation: a prospective cohort study.

J Int Med Res 2021 May;49(5):3000605211014375

Department of Cardiology, Shanghai General Hospital, Shanghai, China.

Objective: The present study aimed to investigate the effect of functional mitral regurgitation (FMR) on recurrence of paroxysmal atrial fibrillation (PAF) in patients undergoing radiofrequency catheter ablation.

Methods: This prospective cohort study comprised 107 patients with PAF. The patients were divided into the FMR and non-FMR groups. Read More

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Balloon occlusion as an adjunctive technique during sclerotherapy of Puig's classified advanced venous malformations.

Phlebology 2021 May 13:2683555211015565. Epub 2021 May 13.

Department of Radiology, Children's Hospital of Pennsylvania, Philadelphia, PA, USA.

Objective: Puig types 2 through 4 venous malformations (VMs) are challenging to treat with sclerotherapy given their robust systemic outflow. Endovenous balloon occlusion offers a means of temporarily occluding systemic venous outflow to allow for more complete sclerotherapy. This study reviews our experience of implementing this technique in patients with Puig advanced (types 2 through 4) VMs. Read More

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Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1.

Mol Med Rep 2021 Jul 13;24(1). Epub 2021 May 13.

Department of Cardiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.

Atherosclerosis is a primary cause of multiple types of cardiovascular disease, including myocardial infarction. In addition, injury of human umbilical vein endothelial cells (HUVECs) can lead to the development of atherosclerosis. Circular (circ)RNAs participate in atherosclerosis. Read More

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Isoquercitrin protects HUVECs against high glucose‑induced apoptosis through regulating p53 proteasomal degradation.

Int J Mol Med 2021 Jul 13;48(1). Epub 2021 May 13.

Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.

High glucose (HG)‑induced endothelial apoptosis serves an important role in the vascular dysfunction associated with diabetes mellitus (DM). It has been reported that isoquercitrin (IQC), a flavonoid glucoside, possesses an anti‑DM effect, but the mechanism requires further investigation. The present study investigated the effect of IQC against HG‑induced apoptosis in human umbilical vein endothelial cells (HUVECs) and explored its molecular mechanism. Read More

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Video-assisted thoracic surgical repair of iatrogenic subclavian vein injury from central venous catheterization.

J Vasc Access 2021 May 13:11297298211015084. Epub 2021 May 13.

Department Critical Care Medicine, Chengdu Fifth People's Hospital, Chengdu, Sichuan, China.

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Barriers in systemic delivery and preclinical testing of synthetic microRNAs in animal models: an experimental study on miR-215-5p mimic.

Physiol Res 2021 May 12. Epub 2021 May 12.

Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.

Mus musculus is the most commonly used animal model in microRNA research; however, little is known about the endogenous miRNome of the animals used in the miRNA-targeting preclinical studies with the human xenografts. In the presented study, we evaluated the NOD/SCID gamma mouse model for the preclinical study of systemic miR-215-5p substitution with a semitelechelic poly[N-(2-hydroxypropyl)methacrylamide]-based carrier conjugated with miR-215-5p-mimic via a reductively degradable disulfide bond. Murine mmu-miR-215-5p and human hsa-miR-215-5p have a high homology of mature sequences with only one nucleotide substitution. Read More

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Clinical Anatomy Considerations on the Muscular and Vascular Components of the Midface by Ultrasonographic Imaging.

Clin Anat 2021 May 12. Epub 2021 May 12.

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.

Introduction: The first signs of face aging appear in the midface, so procedures such as botulinum toxin and filler injections are performed there. However, no guidelines based on clinical anatomy have been published describing the muscular and vascular components in vivo. The aim of this research is to describe the depths of the midface muscles and the locations of vessels using US imaging. Read More

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[The wearable cardioverter defibrillator as diagnostic tool : Case report from remote monitoring daily practice].

Herzschrittmacherther Elektrophysiol 2021 May 12. Epub 2021 May 12.

Katholisches Klinikum Lünen / Werne St.-Marien-Hospital Lünen, Medizinische Klinik 1, Lünen, Deutschland.

Telemedical care can point out new applications of already established therapeutics such as a wearable cardioverter-defibrillator (WCD) and improve the quality of care for chronically ill patients with heart failure through improved management of data derived from this device. The current case report describes the clinical course of a 71-year-old man, who was treated with a WCD in accordance with the current guidelines until a final decision was made about ICD implantation, after acute cardiac decompensation and lately diagnosed severe decrease of left ventricular function in the context of ischaemic cardiomyopathy. The data collected by the WCD were evaluated in a structured way via a telemedicine centre (TMC) and recurrence of the previously known paroxysmal atrial fibrillation (AF) was discovered. Read More

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The effect of perturbations of the glycocalyx on microvascular perfusion in the obese trauma population: an in vitro study.

Trauma Surg Acute Care Open 2021 26;6(1):e000711. Epub 2021 Apr 26.

Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA.

Objectives: Patients with morbid obesity have impaired responses to resuscitation following severe injury, which may contribute to adverse outcomes. Obesity is associated with microvascular dysfunction and metabolic changes associated with altered hemorheological profiles. These include decreased red blood cell (RBC) deformity associated with increased aggregation and adhesion. Read More

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Retinal Pigment Epithelium Adenoma and Adenocarcinoma: A Review.

Ocul Oncol Pathol 2021 Mar 22;7(2):121-132. Epub 2020 Dec 22.

L&T Ocular Pathology Department, Vision Research Foundation, Chennai, India.

Adenoma and adenocarcinoma of the retinal pigment epithelium (RPE) are rare intraocular tumours that are often misdiagnosed as posterior uveal melanoma or other simulating lesions. It is important to be able to differentiate these tumours from melanoma for 3 reasons. First, an inability to rule out melanoma often tilts the management towards enucleation. Read More

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Trends and In-Hospital Outcomes of Splanchnic Vein Thrombosis Associated with Gastrointestinal Malignancies: A Nationwide Analysis.

Gastrointest Tumors 2021 Apr 9;8(2):71-80. Epub 2021 Feb 9.

Department of Oncology, Kansas University Medical Center, Kansas City, Kansas, USA.

Introduction: Gastrointestinal cancers have a strong association with splanchnic vein thrombosis (SVT), yet the hospitalization data is unknown.

Objective And Methods: We analyzed around 78 million discharges from the 2007-2017 Nationwide Inpatient Sample with an inclusion criterion of adult patients admitted for portal or hepatic vein thrombosis as a primary diagnosis with a gastrointestinal or hepatobiliary malignancy as a secondary diagnosis. The outcomes were in-hospital mortality, complication rates, and resource utilization. Read More

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Brainstem Venous Infarction from Thrombosis on the Jugular Bulb as a Serious Complication of Blunt Head Trauma Injury: A Case Report.

Korean J Neurotrauma 2021 Apr 14;17(1):54-60. Epub 2021 Apr 14.

Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

The incidence of dural venous sinus thrombosis (DVST) and the cerebral venous infarct have not exactly known, but DVST is closely related to the skull fracture around the venous sinus. A 56-year-old man experienced massive watery discharge after hitting on his face by a falling machine. He was alert and no cerebrospinal fluid discharge on admission. Read More

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Acute pylephlebitis secondary to perforated sigmoid diverticulitis: A case report.

Radiol Case Rep 2021 Jun 17;16(6):1504-1507. Epub 2021 Apr 17.

Maidstone and Tunbridge Wells NHS Trust, Kent, UK.

Pylephlebitis is defined as the development of portal venous thrombosis secondary to intra-abdominal infection or inflammation. We present the case of a 69-year-old male with pylephlebitis who attended the Emergency Department with nonspecific abdominal pain, rigors and deranged liver function tests. After an initial negative ultrasound study, computed tomography (CT) scanning demonstrated perforated diverticulitis with an associated thrombus within the portal venous system. Read More

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An Overview of Venous Abnormalities Related to the Development of Lesions in Multiple Sclerosis.

Front Neurol 2021 26;12:561458. Epub 2021 Apr 26.

Vascular Diseases Center, University of Ferrara, Ferrara, Italy.

The etiology of multiple sclerosis (MS) is currently understood to be autoimmune. However, there is a long history and growing evidence for disrupted vasculature and flow within the disease pathology. A broad review of the literature related to vascular effects in MS revealed a suggestive role for abnormal flow in the medullary vein system. Read More

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Branch Retinal Vein Occlusion in a Case of Sarcoidosis.

Nepal J Ophthalmol 2021 Jan;13(25):146-151

Reiyukai Eiko Masunaga Eye Hospital, Banepa, Kavre, Nepal.

Background: Sarcoidosis is a chronic inflammatory disorder characterized by non-caseation granuloma. It is an inflammatory disorder of unknown etiology. Sarcoidosis has variable ocular presentations from anterior uveitis to rare venous occlusions. Read More

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January 2021

[Superior Mesenteric Artery Bypass Grafting from the Ascending Aorta Using a Saphenous Vein Graft for Treatment of Acute Aortic Dissection with Abdominal Malperfusion:Report of a Case].

Kyobu Geka 2021 May;74(5):388-391

Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.

A 50-year-old man presented with abdominal pain and numbness in the right leg. He was diagnosed with type A acute aortic dissection with malperfusion of the superior mesenteric artery(SMA) and the right external iliac artery. Before median sternotomy, we made median celiotomy and anastomosed a saphenous vein graft to SMA. Read More

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Unilateral frosted branch angiitis in an human immunodeficiency virus-infected patient with concurrent COVID-19 infection: a case report.

J Med Case Rep 2021 May 12;15(1):267. Epub 2021 May 12.

Department of Ophthalmology, Queen Elizabeth Hospital, Sabah, Malaysia.

Background: Frosted branch angiitis (FBA) is an uncommon ocular sign with multiple causes. With the recent outbreak of coronavirus disease 2019 (COVID-19), many cases of ocular manifestation in association with this disease have been reported. However, as yet we have no complete understanding of this condition. Read More

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Profiling of Primary and Mature miRNA Expression in Atherosclerosis Associated Cell Types.

Arterioscler Thromb Vasc Biol 2021 May 13:ATVBAHA121315579. Epub 2021 May 13.

A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (P.R.M., V.T.B., K.O., T.O., H.H.P., S.Y.-H., J.P.L., S.L.-K., M.U.K.).

Objective: Atherosclerosis is the underlying cause of most cardiovascular diseases. The main cell types associated with disease progression in the vascular wall are endothelial cells, smooth muscle cells, and macrophages. Although their role in atherogenesis has been extensively described, molecular mechanisms underlying gene expression changes remain unknown. Read More

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Correction of Familial LCAT Deficiency by AAV-hLCAT Prevents Renal Injury and Atherosclerosis in Hamsters.

Arterioscler Thromb Vasc Biol 2021 May 13:ATVBAHA120315719. Epub 2021 May 13.

Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, School of Basic Medical Sciences, Peking University, Beijing, China (M.G., W.H., Y.W., G.L., X.X.).

Objective: Familial lecithin:cholesterol acyltransferase (LCAT) deficiency is a rare human disease characterized by very low HDL (high-density lipoprotein) and elevated free cholesterol, in which renal injury has been confirmed in, but whether familial LCAT deficiency patients were at higher risk of atherosclerosis-related cardiovascular disease was highly controversial. Using CRISPR/Cas9 gene-editing technology, we established LCAT knockout (LCAT) hamster model showing both diet-induced and spontaneous atherosclerosis, indicating that this animal model provides a platform for the therapeutic study of renal disease and atherosclerosis caused by LCAT deficiency. Approach and Results: To explore an efficient therapy for familial LCAT deficiency and then investigate whether correction of LCAT deficiency will exert a beneficial role in atherosclerosis-related cardiovascular disease, herein we established a liver-specific adeno-associated virus 8 expressing human LCAT (AAV-hLCAT) to determine the efficacy of gene therapy for dyslipidemia, renal injury, and atherosclerosis-related cardiovascular disease in LCAT hamsters. Read More

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