Am J Transl Res 2021 15;13(5):4120-4136. Epub 2021 May 15.
Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System Tongliao, Inner Mongolia Autonomous Region, China.
Objective: We aimed to investigate the mechanism of circular RNA circ_0084927 in the progression of breast cancer (BC).
Methods: The levels of circ_0084927, miR-142-3p, and ELKS/RAB6-interacting/CAST family member-1 (ERC1) mRNA in the BC tissues and cells were detected by qRT-PCR. CCK8, colony formation, Transwell, and flow cytometry assays were performed to examine the cell proliferation, colony formation, cell invasion, and apoptosis, respectively, in the BC cells with regulated expressions of circ_0084927, miR-142-3p, and ERC1. Read More